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The map label for this gene is lrhA [H]

Identifier: 16765657

GI number: 16765657

Start: 2440125

End: 2441063

Strand: Reverse

Name: lrhA [H]

Synonym: STM2330

Alternate gene names: 16765657

Gene position: 2441063-2440125 (Counterclockwise)

Preceding gene: 16765660

Following gene: 16765656

Centisome position: 50.25

GC content: 52.93

Gene sequence:

>939_bases
ATGATAAATGCAAATCGTCCGATAATTAACCTCGATCTCGATCTGCTGAGAACGTTCGTGGCCGTTGCCGATCTGAACAC
CTTCGCCGCGGCGGCGGCGGCGGTATGTCGTACTCAGTCTGCGGTCAGTCAGCAAATGCAGCGTCTTGAGCAACTCGTGG
GAAAGGAATTGTTCGCCCGCCATGGCCGTAACAAACTTTTGACCGAACACGGTATCCAGCTTCTGGGGTACGCCAGAAAA
ATCCTGCGTTTTAATGATGAGGCGTGTTCATCATTAATGTTCAGTAATCTTCAGGGAGTGTTAACAATCGGCGCTTCTGA
TGAATCAGCTGATACTATCCTGCCTTTTTTGCTTAGCCGAATCAGCTCGGTTTATCCGAAACTCGCGCTTGATGTACGGG
TAAAACGCAACGCCTATATGGTGGACATGGTTAAATCGCAGGAAGTAGATTTGGTGGTGACGACTAACCAACCTCATTCG
CTGGACTGTCTGAATTTGCGGACCTCGCCCACCCATTGGTATTGTGCGGCTGAGTATGTTTTGCAAAGGGGAGAGCCCGT
ACCACTAGTCCTGCTGGACGATCCCAGCCCATTCCGCGATATGGTGCTGGAGACGCTAAATGCAGCGGGTATTCCCTGGC
GGCTGGCCTATGTGGCGTCTACATTACCGGCGGTACGCGCGGCCGTTAAAGCCGGTCTTGGCGTAACGGCTCGACCTGTC
GAAATGATGAGTCCCGACCTTCGCGTGCTGGGCGCCGCAGACGGATTACCGCCTTTGCCGGATACGGAATATCTGTTGTG
CCGCGATCCCAATAGCCAGAACGAGCTGGCGATGGTGATTTTCCATGCGATGGAAAGCTACCAAAACCCATGGCATTACA
ACCAGTTTTCTGCAGAGGGCGGAGATGATCCGCTGATGGTGGAAGGGGGTTTTGAGTAG

Upstream 100 bases:

>100_bases
GGTACTGCGAAGGATGCACATTACAAATGGAATTGCTTGTTTCTGAATGCACAGCATTAACCAGGTCAGCCCGATATGAC
CCGCCAGTAAGTGAAAAATT

Downstream 100 bases:

>100_bases
CTCGCAGGCAAAAGGCGCTAAGTCGTAAATGTAAAAAAGAGCCGCTGGCGATGAAAAAACGCTCAGTGGCTCTTTTTTTG
TGCCCATCTGTACGCGCTTA

Product: NADH dehydrogenase transcriptional repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MINANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFARHGRNKLLTEHGIQLLGYARK
ILRFNDEACSSLMFSNLQGVLTIGASDESADTILPFLLSRISSVYPKLALDVRVKRNAYMVDMVKSQEVDLVVTTNQPHS
LDCLNLRTSPTHWYCAAEYVLQRGEPVPLVLLDDPSPFRDMVLETLNAAGIPWRLAYVASTLPAVRAAVKAGLGVTARPV
EMMSPDLRVLGAADGLPPLPDTEYLLCRDPNSQNELAMVIFHAMESYQNPWHYNQFSAEGGDDPLMVEGGFE

Sequences:

>Translated_312_residues
MINANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFARHGRNKLLTEHGIQLLGYARK
ILRFNDEACSSLMFSNLQGVLTIGASDESADTILPFLLSRISSVYPKLALDVRVKRNAYMVDMVKSQEVDLVVTTNQPHS
LDCLNLRTSPTHWYCAAEYVLQRGEPVPLVLLDDPSPFRDMVLETLNAAGIPWRLAYVASTLPAVRAAVKAGLGVTARPV
EMMSPDLRVLGAADGLPPLPDTEYLLCRDPNSQNELAMVIFHAMESYQNPWHYNQFSAEGGDDPLMVEGGFE
>Mature_312_residues
MINANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFARHGRNKLLTEHGIQLLGYARK
ILRFNDEACSSLMFSNLQGVLTIGASDESADTILPFLLSRISSVYPKLALDVRVKRNAYMVDMVKSQEVDLVVTTNQPHS
LDCLNLRTSPTHWYCAAEYVLQRGEPVPLVLLDDPSPFRDMVLETLNAAGIPWRLAYVASTLPAVRAAVKAGLGVTARPV
EMMSPDLRVLGAADGLPPLPDTEYLLCRDPNSQNELAMVIFHAMESYQNPWHYNQFSAEGGDDPLMVEGGFE

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=312, Percent_Identity=86.2179487179487, Blast_Score=547, Evalue=1e-157,
Organism=Escherichia coli, GI48994962, Length=151, Percent_Identity=30.4635761589404, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787806, Length=134, Percent_Identity=30.5970149253731, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788481, Length=278, Percent_Identity=24.1007194244604, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI145693105, Length=242, Percent_Identity=23.9669421487603, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787879, Length=133, Percent_Identity=36.8421052631579, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790399, Length=276, Percent_Identity=23.5507246376812, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34429; Mature: 34429

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFAR
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGRNKLLTEHGIQLLGYARKILRFNDEACSSLMFSNLQGVLTIGASDESADTILPFLLSR
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHH
ISSVYPKLALDVRVKRNAYMVDMVKSQEVDLVVTTNQPHSLDCLNLRTSPTHWYCAAEYV
HHHHCCHHEEEEEECCCEEEEEEECCCCEEEEEECCCCCCEEEEECCCCCCCCHHHHHHH
LQRGEPVPLVLLDDPSPFRDMVLETLNAAGIPWRLAYVASTLPAVRAAVKAGLGVTARPV
HHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCH
EMMSPDLRVLGAADGLPPLPDTEYLLCRDPNSQNELAMVIFHAMESYQNPWHYNQFSAEG
HHCCCCCEEEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
GDDPLMVEGGFE
CCCCEEEECCCC
>Mature Secondary Structure
MINANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFAR
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGRNKLLTEHGIQLLGYARKILRFNDEACSSLMFSNLQGVLTIGASDESADTILPFLLSR
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHH
ISSVYPKLALDVRVKRNAYMVDMVKSQEVDLVVTTNQPHSLDCLNLRTSPTHWYCAAEYV
HHHHCCHHEEEEEECCCEEEEEEECCCCEEEEEECCCCCCEEEEECCCCCCCCHHHHHHH
LQRGEPVPLVLLDDPSPFRDMVLETLNAAGIPWRLAYVASTLPAVRAAVKAGLGVTARPV
HHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCH
EMMSPDLRVLGAADGLPPLPDTEYLLCRDPNSQNELAMVIFHAMESYQNPWHYNQFSAEG
HHCCCCCEEEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
GDDPLMVEGGFE
CCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]