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The map label for this gene is yfaX [H]

Identifier: 16765619

GI number: 16765619

Start: 2399433

End: 2400215

Strand: Reverse

Name: yfaX [H]

Synonym: STM2292

Alternate gene names: 16765619

Gene position: 2400215-2399433 (Counterclockwise)

Preceding gene: 16765620

Following gene: 16765618

Centisome position: 49.41

GC content: 51.47

Gene sequence:

>783_bases
ATGTTGGAATCAAGTAAAGTCCCGGCTCTTACTCGCGCAATCGACATCCTCAATTTGATCGCGCGTATTGGCCCATGCAG
CGCGGCAATCATTATTGAAACGCTGCGTATTCCAAAAAGCACCGCGTACCTGCTGTTGAATGAATTAAAACGTCAGCGAT
TTATTAGCCTCGATCATCAGGATAACTACTGCCTGTGGACTAAGCTCGTTGAATTGTCGGGTCATGCGCTCAGCAAGATG
GATCTGCGGGAGCTGGCGCGTCCTCGTCTAACACAACTGATGGATGAAACCGGGCTGCTGTGTCACTTGGGGATCATCGA
CCACGAAAATGCGTATTACATACTGAAAGTGGAATCCTCATCCACTATCAGCGTGCGCTCGCATGAGGGGAAAAGCCTCT
CTCTTTATCGTTCCGGCATCGGCAAATGCCTGCTGGCATGGCAGCCGGCCGCCGTACGCAAAGCCATTATTGAACAACTG
GTATGGGAGCGAGCCACGCTGACCACCATCACCGAGCCGCAACAATTGAATGATGAGCTGGAGCGCATTCGCCAGCGAGG
ATGGAGCTTTGATAACGGGGAGGATTATCCGGATGTCCGCTGCGTTGCCGCACCGGTATTTAATGCCAGAAACGAACTGA
CCGCGGCAATTTCAGTGGTCGGCACGCGCCTGCAAATCAACGAAGAGAATCTAGATTATTTGGCCGGTAAAGCTATTGCC
TGTGCCAAAGATATTTCACGCCTGTTGGGATGGAAAAGTCCCTTCGACTCACTCGCATCTTAA

Upstream 100 bases:

>100_bases
CTTCCACTCCGTTGGAAGGCGGATAAGCTTTGACGCGCTTCACAATTTTTTCCCTACTGACCTTTCACACTGATTCCAGT
GTCTCAGACTGGAGTCCAAT

Downstream 100 bases:

>100_bases
AATGGAGAATATTATGACTCTTCCTAAAATTAAACACGTTCGAGCCTGGTTTATTGGGGGCGCTACCGCAGAGAAAGGGG
CTGGCGGCGGGGATTATCAC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLESSKVPALTRAIDILNLIARIGPCSAAIIIETLRIPKSTAYLLLNELKRQRFISLDHQDNYCLWTKLVELSGHALSKM
DLRELARPRLTQLMDETGLLCHLGIIDHENAYYILKVESSSTISVRSHEGKSLSLYRSGIGKCLLAWQPAAVRKAIIEQL
VWERATLTTITEPQQLNDELERIRQRGWSFDNGEDYPDVRCVAAPVFNARNELTAAISVVGTRLQINEENLDYLAGKAIA
CAKDISRLLGWKSPFDSLAS

Sequences:

>Translated_260_residues
MLESSKVPALTRAIDILNLIARIGPCSAAIIIETLRIPKSTAYLLLNELKRQRFISLDHQDNYCLWTKLVELSGHALSKM
DLRELARPRLTQLMDETGLLCHLGIIDHENAYYILKVESSSTISVRSHEGKSLSLYRSGIGKCLLAWQPAAVRKAIIEQL
VWERATLTTITEPQQLNDELERIRQRGWSFDNGEDYPDVRCVAAPVFNARNELTAAISVVGTRLQINEENLDYLAGKAIA
CAKDISRLLGWKSPFDSLAS
>Mature_260_residues
MLESSKVPALTRAIDILNLIARIGPCSAAIIIETLRIPKSTAYLLLNELKRQRFISLDHQDNYCLWTKLVELSGHALSKM
DLRELARPRLTQLMDETGLLCHLGIIDHENAYYILKVESSSTISVRSHEGKSLSLYRSGIGKCLLAWQPAAVRKAIIEQL
VWERATLTTITEPQQLNDELERIRQRGWSFDNGEDYPDVRCVAAPVFNARNELTAAISVVGTRLQINEENLDYLAGKAIA
CAKDISRLLGWKSPFDSLAS

Specific function: Unknown

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788581, Length=260, Percent_Identity=87.3076923076923, Blast_Score=466, Evalue=1e-133,
Organism=Escherichia coli, GI1790752, Length=251, Percent_Identity=31.4741035856574, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788131, Length=221, Percent_Identity=32.1266968325792, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786468, Length=247, Percent_Identity=29.1497975708502, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI87082359, Length=251, Percent_Identity=25.0996015936255, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1789999, Length=213, Percent_Identity=30.9859154929577, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786715, Length=250, Percent_Identity=27.2, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29173; Mature: 29173

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLESSKVPALTRAIDILNLIARIGPCSAAIIIETLRIPKSTAYLLLNELKRQRFISLDHQ
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCC
DNYCLWTKLVELSGHALSKMDLRELARPRLTQLMDETGLLCHLGIIDHENAYYILKVESS
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCC
STISVRSHEGKSLSLYRSGIGKCLLAWQPAAVRKAIIEQLVWERATLTTITEPQQLNDEL
CEEEEECCCCCCHHHHHHCHHHEEEECCCHHHHHHHHHHHHHHHHHHEECCCHHHHHHHH
ERIRQRGWSFDNGEDYPDVRCVAAPVFNARNELTAAISVVGTRLQINEENLDYLAGKAIA
HHHHHHCCCCCCCCCCCCCEEEEHHHHCCHHHHHHHHHHHHEEEEECCCCHHHHHCHHHH
CAKDISRLLGWKSPFDSLAS
HHHHHHHHHCCCCCHHHHCC
>Mature Secondary Structure
MLESSKVPALTRAIDILNLIARIGPCSAAIIIETLRIPKSTAYLLLNELKRQRFISLDHQ
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCC
DNYCLWTKLVELSGHALSKMDLRELARPRLTQLMDETGLLCHLGIIDHENAYYILKVESS
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCC
STISVRSHEGKSLSLYRSGIGKCLLAWQPAAVRKAIIEQLVWERATLTTITEPQQLNDEL
CEEEEECCCCCCHHHHHHCHHHEEEECCCHHHHHHHHHHHHHHHHHHEECCCHHHHHHHH
ERIRQRGWSFDNGEDYPDVRCVAAPVFNARNELTAAISVVGTRLQINEENLDYLAGKAIA
HHHHHHCCCCCCCCCCCCCEEEEHHHHCCHHHHHHHHHHHHEEEEECCCCHHHHHCHHHH
CAKDISRLLGWKSPFDSLAS
HHHHHHHHHCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]