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The map label for this gene is rcsB [H]

Identifier: 16765597

GI number: 16765597

Start: 2369994

End: 2370644

Strand: Direct

Name: rcsB [H]

Synonym: STM2270

Alternate gene names: 16765597

Gene position: 2369994-2370644 (Clockwise)

Preceding gene: 16765596

Following gene: 39546339

Centisome position: 48.79

GC content: 49.0

Gene sequence:

>651_bases
ATGAACAATATGAACGTAATTATTGCCGATGACCACCCGATTGTACTGTTCGGTATTCGCAAATCACTTGAACAAATCGA
GTGGGTGAATGTTGTCGGCGAATTTGAAGATTCCACAGCATTGATCAACAACCTGCCGAAATTAGATGCGCATGTGTTGA
TCACTGACCTCTCCATGCCGGGAGATAAATACGGCGATGGGATCACCTTGATCAAGTACATCAAGCGTCATTTTCCGAGC
CTGTCTATTATCGTTCTGACCATGAACAACAACCCGGCGATCCTGAGCGCCGTGTTGGATCTTGATATTGAAGGGATCGT
ACTCAAACAGGGTGCGCCAACCGATCTGCCTAAGGCGCTGGCCGCGCTGCAAAAAGGCAAAAAATTCACCCCAGAAAGCG
TTTCTCGTCTGCTGGAGAAAATCAGCGCAGGCGGTTACGGCGATAAGCGTCTGTCGCCAAAAGAGAGCGAAGTATTACGC
CTGTTCGCCGAGGGTTTCCTGGTCACCGAAATCGCCAAGAAGCTCAACCGCAGCATTAAGACCATCAGCAGCCAGAAGAA
ATCGGCGATGATGAAACTGGGCGTAGAGAATGATATCGCGCTGCTCAACTATCTCTCTTCTGTCACCCTGAGTCCGACAG
ACAAAGAATAA

Upstream 100 bases:

>100_bases
GAACATCTGATTCGTGAGAAAGATGCTCCAGGTATAGAAAAATATATCAGCGACATTGACGCCTACGTCAAAAGCTTGCT
GTAGCAAGGTAGCCCAATAC

Downstream 100 bases:

>100_bases
ATCGCTTTTATGTTACCCAGCCTGATGGCGCTACGCTTATCAGGCCTACCAGTCGACTCATCTTTTACAGGCCGGACAGG
CGACGCCGCCATCCGGCATT

Product: transcriptional regulator RcsB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPS
LSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLR
LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPTDKE

Sequences:

>Translated_216_residues
MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPS
LSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLR
LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPTDKE
>Mature_216_residues
MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPS
LSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLR
LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPTDKE

Specific function: Also stimulates ftsZ expression. This suggests that rcsB is a regulator implicated in the regulation of more than one cellular function [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788546, Length=216, Percent_Identity=99.0740740740741, Blast_Score=430, Evalue=1e-122,
Organism=Escherichia coli, GI1788521, Length=200, Percent_Identity=31, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788222, Length=207, Percent_Identity=26.5700483091787, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1790102, Length=199, Percent_Identity=30.1507537688442, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1786747, Length=206, Percent_Identity=27.1844660194175, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788712, Length=190, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23715; Mature: 23715

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMP
CCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEEECCCC
GDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKAL
CCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCEEHHHHHCCCCEEEEECCCCCCHHHHH
AALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIK
HHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TISSQKKSAMMKLGVENDIALLNYLSSVTLSPTDKE
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMP
CCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEEECCCC
GDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKAL
CCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCEEHHHHHCCCCEEEEECCCCCCHHHHH
AALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIK
HHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TISSQKKSAMMKLGVENDIALLNYLSSVTLSPTDKE
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]