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The map label for this gene is mdtA [H]

Identifier: 16765456

GI number: 16765456

Start: 2214284

End: 2215525

Strand: Direct

Name: mdtA [H]

Synonym: STM2126

Alternate gene names: 16765456

Gene position: 2214284-2215525 (Clockwise)

Preceding gene: 16765455

Following gene: 16765457

Centisome position: 45.59

GC content: 58.05

Gene sequence:

>1242_bases
ATGAAAGGCAGTAATACTTTCCGCTGGGCAATAGCGATTGGGGTTGTAGTGGCCGCCGCCGCATTCTGGTTCTGGCATAG
CCGTAGCGAAAGCCCGACCGCCGCGCCAGGCGTCGCCGCGCAAGCGCCGCATACCGCCTCCGCAGGTCGCCGCGGTATGC
GCGACGGCCCTCTGGCGCCGGTACAGGCCGCGACCGCGACCACGCAGGCCGTACCGCGCTATCTGAGCGGGCTGGGTACC
GTGACCGCCGCGAATACCGTTACGGTGCGTAGCCGCGTGGATGGTCAACTCATCGCCCTGCACTTTCAGGAAGGTCAGCA
GGTCAACGCAGGCGATCTGCTGGCGCAAATCGATCCCAGCCAGTTTAAGGTCGCCCTGGCGCAGGCTCAGGGACAGTTGG
CGAAAGATAACGCTACGCTGGCGAATGCGCGTCGTGATCTGGCGCGCTATCAGCAACTGGCAAAAACCAATCTGGTTTCC
CGTCAGGAACTGGATGCGCAACAGGCGCTGGTCAACGAAACCCAGGGAACCATTAAAGCGGATGAAGCTAATGTCGCCAG
CGCGCAGTTACAGCTCGACTGGAGTCGTATCACGGCCCCGGTCTCGGGACGCGTGGGTCTGAAACAGGTGGATGTCGGCA
ACCAGATTTCCAGCAGCGATACCGCAGGTATTGTCGTCATTACGCAAACGCACCCGATTGATCTCATTTTTACTCTGCCG
GAAAGCGATATCGCGACCGTAGTTCAGGCACAGAAAGCGGGGAAAGCGCTGGTCGTAGAAGCCTGGGATCGGACTAACTC
GCACAAATTGAGCGAAGGTGTGTTGCTCAGTCTGGACAACCAGATTGATCCCACGACGGGAACGATCAAAATTAAAGCGC
GCTTTACCAATCAGGACGATACGCTGTTCCCCAATCAATTTGTGAACGCCCGGATGCTGGTCGATACCGAACAAAATGCC
GTTGTGGTGCCTGCCGCGGCGGTGCAAATGGGCAATGAGGGCCACTTTGTGTGGGTGCTGAACGACGAAAATAACGTCAG
CAAGAAGCGGGTAAAAATCGGTATTCAGGATAACCGAAACGTGGTGATCAGCGCAGGCTTATCGGCAGGCGATCGCGTCG
TTACCGATGGTATTGATCGGCTGACGGAAGGCGCAAAAGTCGAGGTCGTTGAGCCGCAAACCACCGTGGCGGATGAAAAA
TCCCCTTCCCGCCATGAAGGTCAAAAAGGAGCGCGCGCCTGA

Upstream 100 bases:

>100_bases
GACCGTGTTCCATAATTCCTCCATTTTTCTCCCTTCCCTGCTGACTACAATAGAGGAAGCAACATTCCGCAAAACGTTTC
AGGATGAGAAACTTATACCG

Downstream 100 bases:

>100_bases
TGCAGGTATTACCTCCGGGCAGCACGGGCGGCCCTTCGCGTCTGTTTATTCTGCGCCCCGTGGCCACCACTCTGCTGATG
GCGGCGATTTTACTCGCCGG

Product: multidrug efflux system subunit MdtA

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKGSNTFRWAIAIGVVVAAAAFWFWHSRSESPTAAPGVAAQAPHTASAGRRGMRDGPLAPVQAATATTQAVPRYLSGLGT
VTAANTVTVRSRVDGQLIALHFQEGQQVNAGDLLAQIDPSQFKVALAQAQGQLAKDNATLANARRDLARYQQLAKTNLVS
RQELDAQQALVNETQGTIKADEANVASAQLQLDWSRITAPVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLP
ESDIATVVQAQKAGKALVVEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDDTLFPNQFVNARMLVDTEQNA
VVVPAAAVQMGNEGHFVWVLNDENNVSKKRVKIGIQDNRNVVISAGLSAGDRVVTDGIDRLTEGAKVEVVEPQTTVADEK
SPSRHEGQKGARA

Sequences:

>Translated_413_residues
MKGSNTFRWAIAIGVVVAAAAFWFWHSRSESPTAAPGVAAQAPHTASAGRRGMRDGPLAPVQAATATTQAVPRYLSGLGT
VTAANTVTVRSRVDGQLIALHFQEGQQVNAGDLLAQIDPSQFKVALAQAQGQLAKDNATLANARRDLARYQQLAKTNLVS
RQELDAQQALVNETQGTIKADEANVASAQLQLDWSRITAPVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLP
ESDIATVVQAQKAGKALVVEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDDTLFPNQFVNARMLVDTEQNA
VVVPAAAVQMGNEGHFVWVLNDENNVSKKRVKIGIQDNRNVVISAGLSAGDRVVTDGIDRLTEGAKVEVVEPQTTVADEK
SPSRHEGQKGARA
>Mature_413_residues
MKGSNTFRWAIAIGVVVAAAAFWFWHSRSESPTAAPGVAAQAPHTASAGRRGMRDGPLAPVQAATATTQAVPRYLSGLGT
VTAANTVTVRSRVDGQLIALHFQEGQQVNAGDLLAQIDPSQFKVALAQAQGQLAKDNATLANARRDLARYQQLAKTNLVS
RQELDAQQALVNETQGTIKADEANVASAQLQLDWSRITAPVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLP
ESDIATVVQAQKAGKALVVEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDDTLFPNQFVNARMLVDTEQNA
VVVPAAAVQMGNEGHFVWVLNDENNVSKKRVKIGIQDNRNVVISAGLSAGDRVVTDGIDRLTEGAKVEVVEPQTTVADEK
SPSRHEGQKGARA

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=415, Percent_Identity=82.4096385542169, Blast_Score=666, Evalue=0.0,
Organism=Escherichia coli, GI1789929, Length=312, Percent_Identity=30.1282051282051, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1789665, Length=321, Percent_Identity=30.2180685358255, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786668, Length=322, Percent_Identity=30.4347826086957, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI87081951, Length=195, Percent_Identity=30.2564102564103, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081796, Length=315, Percent_Identity=26.031746031746, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44051; Mature: 44051

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGSNTFRWAIAIGVVVAAAAFWFWHSRSESPTAAPGVAAQAPHTASAGRRGMRDGPLAP
CCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCC
VQAATATTQAVPRYLSGLGTVTAANTVTVRSRVDGQLIALHFQEGQQVNAGDLLAQIDPS
CHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCCEEEEEEECCCCCCCCCCEEEEECHH
QFKVALAQAQGQLAKDNATLANARRDLARYQQLAKTNLVSRQELDAQQALVNETQGTIKA
HHHEEEEHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEE
DEANVASAQLQLDWSRITAPVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLP
CCCCEEEEEEEEEHHHEECCCCCCCCCEEECCCCCCCCCCCCEEEEEEECCCEEEEEECC
ESDIATVVQAQKAGKALVVEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDD
CCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCC
TLFPNQFVNARMLVDTEQNAVVVPAAAVQMGNEGHFVWVLNDENNVSKKRVKIGIQDNRN
CCCCCHHCCEEEEEECCCCEEEEEHHHEEECCCCCEEEEECCCCCCCEEEEEEEEECCCE
VVISAGLSAGDRVVTDGIDRLTEGAKVEVVEPQTTVADEKSPSRHEGQKGARA
EEEECCCCCCCEEHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHCCCCCCCC
>Mature Secondary Structure
MKGSNTFRWAIAIGVVVAAAAFWFWHSRSESPTAAPGVAAQAPHTASAGRRGMRDGPLAP
CCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCC
VQAATATTQAVPRYLSGLGTVTAANTVTVRSRVDGQLIALHFQEGQQVNAGDLLAQIDPS
CHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCCEEEEEEECCCCCCCCCCEEEEECHH
QFKVALAQAQGQLAKDNATLANARRDLARYQQLAKTNLVSRQELDAQQALVNETQGTIKA
HHHEEEEHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEE
DEANVASAQLQLDWSRITAPVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLP
CCCCEEEEEEEEEHHHEECCCCCCCCCEEECCCCCCCCCCCCEEEEEEECCCEEEEEECC
ESDIATVVQAQKAGKALVVEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDD
CCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCC
TLFPNQFVNARMLVDTEQNAVVVPAAAVQMGNEGHFVWVLNDENNVSKKRVKIGIQDNRN
CCCCCHHCCEEEEEECCCCEEEEEHHHEEECCCCCEEEEECCCCCCCEEEEEEEEECCCE
VVISAGLSAGDRVVTDGIDRLTEGAKVEVVEPQTTVADEKSPSRHEGQKGARA
EEEECCCCCCCEEHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA