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The map label for this gene is wzzB

Identifier: 16765409

GI number: 16765409

Start: 2156832

End: 2157815

Strand: Reverse

Name: wzzB

Synonym: STM2079

Alternate gene names: 16765409

Gene position: 2157815-2156832 (Counterclockwise)

Preceding gene: 16765410

Following gene: 16765400

Centisome position: 44.42

GC content: 50.41

Gene sequence:

>984_bases
ATGACAGTGGATAGTAATACGTCTTCCGGGCGTGGGAACGATCCGGAACAGATTGATTTGATTGAGTTATTGCTACAGTT
ATGGCGTGGGAAGATGACCATTATTGTAGCCGTTATTATCGCCATTTTGCTGGCTGTAGGCTACCTGATGATAGCCAAAG
AAAAATGGACATCCACGGCGATTATTACCCAACCTGATGCCGCGCAGGTTGCCACCTATACCAACGCGCTCAACGTCTTG
TATGGTGGGAATGCCCCCAAAATCTCTGAAGTGCAGGCGAATTTTATAAGCCGCTTTAGCTCTGCGTTTTCCGCATTATC
GGAAGTGCTGGATAATCAGAAAGAGCGGGAAAAGCTTACCATTGAACAGTCGGTAAAAGGGCAGGCGCTGCCACTCTCGG
TTTCTTATGTGAGTACTACCGCTGAAGGGGCGCAGCGTCGGCTGGCGGAATATATCCAACAGGTGGATGAAGAGGTCGCT
AAGGAACTGGAAGTTGACCTGAAAGATAACATCACGCTGCAAACCAAAACGTTGCAGGAGTCCCTTGAGACGCAGGAAGT
TGTGGCGCAGGAGCAAAAAGATCTGCGTATTAAGCAAATCGAAGAAGCGTTGCGCTATGCGGATGAGGCCAAAATCACGC
AGCCGCAGATTCAGCAAACCCAGGATGTTACCCAGGACACGATGTTCCTGTTGGGGAGCGATGCGCTAAAATCGATGATA
CAGAACGAAGCGACGCGTCCACTGGTCTTTTCTCCGGCCTATTACCAGACGAAGCAGACACTGCTGGACATTAAAAATCT
GAAAGTGACTGCCGATACGGTGCACGTCTATCGTTATGTGATGAAGCCGACGCTGCCGGTCCGTCGCGATAGCCCGAAAA
CAGCCATTACCCTTGTGCTGGCTGTATTGCTGGGTGGGATGATCGGTGCCGGGATTGTGCTGGGACGCAATGCGCTACGT
AGCTATAAGCCAAAAGCCTTGTAA

Upstream 100 bases:

>100_bases
AATGGAAATAATGTCTGATTTTTATCATTAATCCTATGGCATATATTTGCTTTATGGCTACACTGTCTCCAGCTTCATCC
TTTTTTTAGTTAGGGTATCT

Downstream 100 bases:

>100_bases
GCTTCTTTGCCGGATGGTGGTCGGCTACGACAGGTAAAATTTCTCATTAAAAAACCGGGCATTGCCCGGTTTTTTTACGC
TTATTGATGACGCTTACGAA

Product: lipopolysaccharide O-antigen chain length regulator

Products: NA

Alternate protein names: Polysaccharide antigen chain regulator

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTVDSNTSSGRGNDPEQIDLIELLLQLWRGKMTIIVAVIIAILLAVGYLMIAKEKWTSTAIITQPDAAQVATYTNALNVL
YGGNAPKISEVQANFISRFSSAFSALSEVLDNQKEREKLTIEQSVKGQALPLSVSYVSTTAEGAQRRLAEYIQQVDEEVA
KELEVDLKDNITLQTKTLQESLETQEVVAQEQKDLRIKQIEEALRYADEAKITQPQIQQTQDVTQDTMFLLGSDALKSMI
QNEATRPLVFSPAYYQTKQTLLDIKNLKVTADTVHVYRYVMKPTLPVRRDSPKTAITLVLAVLLGGMIGAGIVLGRNALR
SYKPKAL

Sequences:

>Translated_327_residues
MTVDSNTSSGRGNDPEQIDLIELLLQLWRGKMTIIVAVIIAILLAVGYLMIAKEKWTSTAIITQPDAAQVATYTNALNVL
YGGNAPKISEVQANFISRFSSAFSALSEVLDNQKEREKLTIEQSVKGQALPLSVSYVSTTAEGAQRRLAEYIQQVDEEVA
KELEVDLKDNITLQTKTLQESLETQEVVAQEQKDLRIKQIEEALRYADEAKITQPQIQQTQDVTQDTMFLLGSDALKSMI
QNEATRPLVFSPAYYQTKQTLLDIKNLKVTADTVHVYRYVMKPTLPVRRDSPKTAITLVLAVLLGGMIGAGIVLGRNALR
SYKPKAL
>Mature_326_residues
TVDSNTSSGRGNDPEQIDLIELLLQLWRGKMTIIVAVIIAILLAVGYLMIAKEKWTSTAIITQPDAAQVATYTNALNVLY
GGNAPKISEVQANFISRFSSAFSALSEVLDNQKEREKLTIEQSVKGQALPLSVSYVSTTAEGAQRRLAEYIQQVDEEVAK
ELEVDLKDNITLQTKTLQESLETQEVVAQEQKDLRIKQIEEALRYADEAKITQPQIQQTQDVTQDTMFLLGSDALKSMIQ
NEATRPLVFSPAYYQTKQTLLDIKNLKVTADTVHVYRYVMKPTLPVRRDSPKTAITLVLAVLLGGMIGAGIVLGRNALRS
YKPKAL

Specific function: Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 20

COG id: COG3765

COG function: function code M; Chain length determinant protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the wzzB/cld/rol family

Homologues:

Organism=Escherichia coli, GI87082029, Length=326, Percent_Identity=72.0858895705521, Blast_Score=474, Evalue=1e-135,
Organism=Escherichia coli, GI87082332, Length=333, Percent_Identity=27.3273273273273, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786802, Length=349, Percent_Identity=28.080229226361, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): WZZB_SALTY (Q04866)

Other databases:

- EMBL:   Z17278
- EMBL:   M89933
- EMBL:   AE006468
- RefSeq:   NP_461024.1
- PDB:   3B8P
- PDBsum:   3B8P
- ProteinModelPortal:   Q04866
- SMR:   Q04866
- DIP:   DIP-46396N
- PRIDE:   Q04866
- GeneID:   1253600
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM2079
- NMPDR:   fig|99287.1.peg.2004
- HOGENOM:   HBG417280
- OMA:   WTSTAIV
- ProtClustDB:   PRK15471
- BioCyc:   STYP99287:STM2079-MONOMER
- InterPro:   IPR003856

Pfam domain/function: PF02706 Wzz

EC number: NA

Molecular weight: Translated: 36259; Mature: 36128

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc90d154)-; HASH(0xf4f41b4)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVDSNTSSGRGNDPEQIDLIELLLQLWRGKMTIIVAVIIAILLAVGYLMIAKEKWTSTA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IITQPDAAQVATYTNALNVLYGGNAPKISEVQANFISRFSSAFSALSEVLDNQKEREKLT
EEECCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
IEQSVKGQALPLSVSYVSTTAEGAQRRLAEYIQQVDEEVAKELEVDLKDNITLQTKTLQE
HHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHH
SLETQEVVAQEQKDLRIKQIEEALRYADEAKITQPQIQQTQDVTQDTMFLLGSDALKSMI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHH
QNEATRPLVFSPAYYQTKQTLLDIKNLKVTADTVHVYRYVMKPTLPVRRDSPKTAITLVL
HCCCCCCEEECCHHHHHHHHHHHHHCCEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
AVLLGGMIGAGIVLGRNALRSYKPKAL
HHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure 
TVDSNTSSGRGNDPEQIDLIELLLQLWRGKMTIIVAVIIAILLAVGYLMIAKEKWTSTA
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IITQPDAAQVATYTNALNVLYGGNAPKISEVQANFISRFSSAFSALSEVLDNQKEREKLT
EEECCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
IEQSVKGQALPLSVSYVSTTAEGAQRRLAEYIQQVDEEVAKELEVDLKDNITLQTKTLQE
HHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHH
SLETQEVVAQEQKDLRIKQIEEALRYADEAKITQPQIQQTQDVTQDTMFLLGSDALKSMI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHH
QNEATRPLVFSPAYYQTKQTLLDIKNLKVTADTVHVYRYVMKPTLPVRRDSPKTAITLVL
HCCCCCCEEECCHHHHHHHHHHHHHCCEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
AVLLGGMIGAGIVLGRNALRSYKPKAL
HHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7682279; 1379582; 11677609