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The map label for this gene is cbiQ

Identifier: 16765351

GI number: 16765351

Start: 2102023

End: 2102700

Strand: Reverse

Name: cbiQ

Synonym: STM2021

Alternate gene names: 16765351

Gene position: 2102700-2102023 (Counterclockwise)

Preceding gene: 16765352

Following gene: 16765350

Centisome position: 43.29

GC content: 54.28

Gene sequence:

>678_bases
ATGACCGGGCTTGATCGACTCAGCTATCAAAGCCGCTGGGCACACGTTGCGCCGCAGCGCAAGTTTTTGCTGTGGCTGGC
GATGATGATACTGGCGTTTGTTCTGCCGCCTGTAGGGCAGGGCATTGAGCTGCTGATCATTGCCGGATTGAGCTGTTGGC
TATTGCGCATATCCCTCTGGCGCTGGTGTCGATGGATGGCGATACCTTTTGGATTTTTGTTGGTCGGCGTGATAACGATT
ATCTTCAGCATCAGCCGCGAGCCGCAAATGCTGCTGGCTGGCATATCTGTTGGGCCGTACTGGATCGGGATTACCCGTGC
GGGCGTGGTTACGGCGAATGAAACGTTCTGGCGTAGCCTGACGGCGCTGTCCGCGACGTTGTGGCTGGTGATGAACCTAC
CGTTTCCGCAGTTAATTAGCTTGCTTAAGCGCGCGCATATTCCACGCCTGCTTACCGAGCAAATCCTGTTAACGTGGCGC
TTTCTCTTTATTCTTCTGGATGAGGCGGTGGCAATCCGTCGTGCGCAAACGCTGCGTTTTGGTTATTGCAGCCTGCCGAA
CGGCTATCGATCTCTGGCGATGCTGGCTGGACTCCTGTTTACGCGGGTGTTAATGCGTTATCAGCAAATGACCACCACGC
TGGATATCAAACTGTATCAGGGTGATTTTCACCTGTAA

Upstream 100 bases:

>100_bases
AGCGGTGAAATTGAAAGCCTGCTGTTTACCCTTCAGGGCTCTCTTGGCGCGGCGGTGATTTTTTATATCCTGGGGTATTG
CAAAGGTAAACAACGCCGTG

Downstream 100 bases:

>100_bases
GGACTATTATGCTTGCCACTTCAGACCTGTGGTTTCGTTATCAGAATGAGCCGGTACTTAAAGGGTTAAATATGGATTTT
TCGCTTTCGCCTGTTACCGG

Product: vitamin B12 biosynthetic protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTGLDRLSYQSRWAHVAPQRKFLLWLAMMILAFVLPPVGQGIELLIIAGLSCWLLRISLWRWCRWMAIPFGFLLVGVITI
IFSISREPQMLLAGISVGPYWIGITRAGVVTANETFWRSLTALSATLWLVMNLPFPQLISLLKRAHIPRLLTEQILLTWR
FLFILLDEAVAIRRAQTLRFGYCSLPNGYRSLAMLAGLLFTRVLMRYQQMTTTLDIKLYQGDFHL

Sequences:

>Translated_225_residues
MTGLDRLSYQSRWAHVAPQRKFLLWLAMMILAFVLPPVGQGIELLIIAGLSCWLLRISLWRWCRWMAIPFGFLLVGVITI
IFSISREPQMLLAGISVGPYWIGITRAGVVTANETFWRSLTALSATLWLVMNLPFPQLISLLKRAHIPRLLTEQILLTWR
FLFILLDEAVAIRRAQTLRFGYCSLPNGYRSLAMLAGLLFTRVLMRYQQMTTTLDIKLYQGDFHL
>Mature_224_residues
TGLDRLSYQSRWAHVAPQRKFLLWLAMMILAFVLPPVGQGIELLIIAGLSCWLLRISLWRWCRWMAIPFGFLLVGVITII
FSISREPQMLLAGISVGPYWIGITRAGVVTANETFWRSLTALSATLWLVMNLPFPQLISLLKRAHIPRLLTEQILLTWRF
LFILLDEAVAIRRAQTLRFGYCSLPNGYRSLAMLAGLLFTRVLMRYQQMTTTLDIKLYQGDFHL

Specific function: May be involved with cobalt transport in association with cobalamin biosynthesis

COG id: COG0619

COG function: function code P; ABC-type cobalt transport system, permease component CbiQ and related transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiQ family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CBIQ_SALTY (Q05598)

Other databases:

- EMBL:   L12006
- EMBL:   AE006468
- RefSeq:   NP_460966.1
- GeneID:   1253542
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM2021
- NMPDR:   fig|99287.1.peg.1946
- HOGENOM:   HBG672287
- OMA:   IYRFIFI
- ProtClustDB:   PRK15485
- BioCyc:   STYP99287:STM2021-MONOMER
- InterPro:   IPR003339
- InterPro:   IPR012809
- TIGRFAMs:   TIGR02454

Pfam domain/function: PF02361 CbiQ

EC number: NA

Molecular weight: Translated: 25885; Mature: 25753

Theoretical pI: Translated: 11.07; Mature: 11.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf905fd0)-; HASH(0xf7341bc)-; HASH(0xf61a68c)-; HASH(0xf506f34)-; HASH(0xb41e514)-;

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLDRLSYQSRWAHVAPQRKFLLWLAMMILAFVLPPVGQGIELLIIAGLSCWLLRISLW
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
RWCRWMAIPFGFLLVGVITIIFSISREPQMLLAGISVGPYWIGITRAGVVTANETFWRSL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCCEEEEEEECCEEECCHHHHHHH
TALSATLWLVMNLPFPQLISLLKRAHIPRLLTEQILLTWRFLFILLDEAVAIRRAQTLRF
HHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYCSLPNGYRSLAMLAGLLFTRVLMRYQQMTTTLDIKLYQGDFHL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCH
>Mature Secondary Structure 
TGLDRLSYQSRWAHVAPQRKFLLWLAMMILAFVLPPVGQGIELLIIAGLSCWLLRISLW
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
RWCRWMAIPFGFLLVGVITIIFSISREPQMLLAGISVGPYWIGITRAGVVTANETFWRSL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCCEEEEEEECCEEECCHHHHHHH
TALSATLWLVMNLPFPQLISLLKRAHIPRLLTEQILLTWRFLFILLDEAVAIRRAQTLRF
HHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYCSLPNGYRSLAMLAGLLFTRVLMRYQQMTTTLDIKLYQGDFHL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609