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The map label for this gene is mppA [H]

Identifier: 16765022

GI number: 16765022

Start: 1771997

End: 1773610

Strand: Reverse

Name: mppA [H]

Synonym: STM1679

Alternate gene names: 16765022

Gene position: 1773610-1771997 (Counterclockwise)

Preceding gene: 16765024

Following gene: 16765020

Centisome position: 36.51

GC content: 48.82

Gene sequence:

>1614_bases
ATGAGGCATTCTGTTTCAGTAACCTGTTGTGCGCTGTTGGTTAGCAGCTTTTCCCTGGCATATGCTGCGGATGTTCCCGG
CGGAACGGTACTGGCAGAAAAACAAGAACTGGTGCGTCATATCAAAGATGAGCCCGCTTCGTTAGATCCAGCGAAAGCCG
TTGGGCTGCCTGAAATTCAGGTGATCCGCGATCTGTTTGAAGGGCTGGTTAACCAGAACGAAAAGGGTGAAATTATCCCT
GGCGTCGCCAGCCAGTGGAAGAGCAATGATAATCGTATCTGGACGTTTACGTTGCGGGATGATGCGCAATGGGCCGATGG
AACGCCGGTGACCGCCCAGGATTTTGTCTATAGCTGGCAACGCCTCGTTGATCCCAAAACGCTTTCCCCCTTCGCCTGGT
TTGCCGCTCTGGCTGGCATCACTAATGCACAAGCCATTATCGACGGTAAAGTCACGCCGGATCAGCTTGGCGTCAGTGCC
GTGGACGCGCACACTTTGCGTGTTCAGCTTGACAAGCCGTTGCCCTGGTTTGCCAGTCTGACCGCCAGTTTTGCCTTTTA
TCCGGTCCAAAAAGCGAATGTTGAAAGCGGCAAAGACTGGATGAAGCCGGGAAAACTGATTGGCAATGGCGCGTATGTTC
TTAAAGAGCGCGTGGTAAATGAAAAACTGGTGGTCGTGCCTAATACGCATTACTGGGATAACGCGAAAACGGTACTGCAA
AAAGTAACATTTTTACCCATTAACCAGGAATCGGCTGCGACGAAACGTTACCTTGCCGGTGATATTGATATCACCGAATC
TTTCCCTAAAAATATGTACCAGAAATTATTGAAGGATATTCCAGGGCAAGTTTATACACCGCCGCAATTAGGGACTTATT
ATTATGCGTTTAATACGCAGAAAGGGCCGACGGCGGATTCCCGCGTTCGTCTGGCGCTAAGTATGACCATTGATCGCCGT
TTGATGGCGGAAAAAGTCTTAGGTACCGGTGAAAAACCGGCCTGGCATTTTACACCGGATGTCACGGCAGGATTTACGCC
CGATCCTTCACCGTTTGAACAAATGAGCCAGGAAGAACTTAATGCCCAGGCGAAAACATTGCTGCGTGCAGCAGGCTACG
GATCGCAGAAGCCGCTTAAATTAACCCTGCTTTACAATACCTCAGAAAACCATCAGAAAATCGCGATTGCGGTGGCGTCA
ATGTGGAAGAAAAATCTGGGGGTGGATGTGAAATTGCAAAACCAGGAGTGGAAAACGTATATCGACAGCCGGAATACCGG
TAATTTTGATGTTATTCGCGCCTCCTGGGTGGGTGATTACAACGAACCGTCGACTTTCTTATCCTTATTAACGTCCACGC
ATACGGGGAATATTTCACGCTTTACTAATCCGACTTATGACAAAATCCTGACGCAAGCGACGATGGAAAATACTGCCGAA
GCGCGTAACGCGGATTACAATGCAGCGGAGAAAATTTTAACGGAACAAGCGCCTATAGCGCCTATTTATCAGTATACCAA
TGGCCGGTTAATTAAACCGTGGGTAAAGGGATACCCCATTACTAACCCGGAAGATGTGGCCTATAGCCGTACAATGTATA
TCGTGAAGCACTGA

Upstream 100 bases:

>100_bases
TGTATGGCGCGATATCAACTTTCTGGCGGAAGATAATTGCATTTCTTTCTGCTGAAACAAATAATTACGTTGTCATTTAA
CTCATCTTTGAGGAACTTCT

Downstream 100 bases:

>100_bases
TGCGTACTGGTTTCTTGTTAACGCAAGGTAGCCACGCCCGCCGCCTGATGCTGGCAGAAGGCATGGGGATTAAGCGAGCG
CCTGATGCCGCCGTTCTCAT

Product: periplasmic murein tripeptide transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 537

Protein sequence:

>537_residues
MRHSVSVTCCALLVSSFSLAYAADVPGGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIIP
GVASQWKSNDNRIWTFTLRDDAQWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGITNAQAIIDGKVTPDQLGVSA
VDAHTLRVQLDKPLPWFASLTASFAFYPVQKANVESGKDWMKPGKLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQ
KVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADSRVRLALSMTIDRR
LMAEKVLGTGEKPAWHFTPDVTAGFTPDPSPFEQMSQEELNAQAKTLLRAAGYGSQKPLKLTLLYNTSENHQKIAIAVAS
MWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLSLLTSTHTGNISRFTNPTYDKILTQATMENTAE
ARNADYNAAEKILTEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSRTMYIVKH

Sequences:

>Translated_537_residues
MRHSVSVTCCALLVSSFSLAYAADVPGGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIIP
GVASQWKSNDNRIWTFTLRDDAQWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGITNAQAIIDGKVTPDQLGVSA
VDAHTLRVQLDKPLPWFASLTASFAFYPVQKANVESGKDWMKPGKLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQ
KVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADSRVRLALSMTIDRR
LMAEKVLGTGEKPAWHFTPDVTAGFTPDPSPFEQMSQEELNAQAKTLLRAAGYGSQKPLKLTLLYNTSENHQKIAIAVAS
MWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLSLLTSTHTGNISRFTNPTYDKILTQATMENTAE
ARNADYNAAEKILTEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSRTMYIVKH
>Mature_537_residues
MRHSVSVTCCALLVSSFSLAYAADVPGGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIIP
GVASQWKSNDNRIWTFTLRDDAQWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGITNAQAIIDGKVTPDQLGVSA
VDAHTLRVQLDKPLPWFASLTASFAFYPVQKANVESGKDWMKPGKLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQ
KVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADSRVRLALSMTIDRR
LMAEKVLGTGEKPAWHFTPDVTAGFTPDPSPFEQMSQEELNAQAKTLLRAAGYGSQKPLKLTLLYNTSENHQKIAIAVAS
MWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLSLLTSTHTGNISRFTNPTYDKILTQATMENTAE
ARNADYNAAEKILTEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSRTMYIVKH

Specific function: Essential for the uptake of the murein peptide L-alanyl- gamma-D-glutamyl-meso-diaminopimelate. Also transports some alpha- linked peptides such as Pro-Phe-Lys with low affinity. The transport is effected by the oligopeptide permease system [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI87081878, Length=537, Percent_Identity=92.7374301675978, Blast_Score=1050, Evalue=0.0,
Organism=Escherichia coli, GI1787495, Length=539, Percent_Identity=48.4230055658627, Blast_Score=505, Evalue=1e-144,
Organism=Escherichia coli, GI1789397, Length=529, Percent_Identity=43.1001890359168, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1787762, Length=541, Percent_Identity=28.4658040665434, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1789887, Length=480, Percent_Identity=23.9583333333333, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1789966, Length=466, Percent_Identity=22.7467811158798, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59878; Mature: 59878

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHSVSVTCCALLVSSFSLAYAADVPGGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQ
CCCCCHHHHHHHHHHHCCCEEEECCCCCCEEHHHHHHHHHHCCCCCCCCHHHHCCCCHHH
VIRDLFEGLVNQNEKGEIIPGVASQWKSNDNRIWTFTLRDDAQWADGTPVTAQDFVYSWQ
HHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHH
RLVDPKTLSPFAWFAALAGITNAQAIIDGKVTPDQLGVSAVDAHTLRVQLDKPLPWFASL
HHCCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHCCEEECCEEEEEEECCCCCHHHHH
TASFAFYPVQKANVESGKDWMKPGKLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQ
HHHHEEEECCCCCCCCCHHHCCCCCEECCCHHHHHHHHCCCEEEEECCCCCCCCHHHHHH
KVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQ
HHHEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEECC
KGPTADSRVRLALSMTIDRRLMAEKVLGTGEKPAWHFTPDVTAGFTPDPSPFEQMSQEEL
CCCCCCCEEEEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHH
NAQAKTLLRAAGYGSQKPLKLTLLYNTSENHQKIAIAVASMWKKNLGVDVKLQNQEWKTY
HHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHCCCEEEEECCCHHHHH
IDSRNTGNFDVIRASWVGDYNEPSTFLSLLTSTHTGNISRFTNPTYDKILTQATMENTAE
HCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ARNADYNAAEKILTEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSRTMYIVKH
HCCCCCHHHHHHHHCCCCCCCEEEECCCEEECHHHCCCCCCCCCCCEEEEEEEEEEC
>Mature Secondary Structure
MRHSVSVTCCALLVSSFSLAYAADVPGGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQ
CCCCCHHHHHHHHHHHCCCEEEECCCCCCEEHHHHHHHHHHCCCCCCCCHHHHCCCCHHH
VIRDLFEGLVNQNEKGEIIPGVASQWKSNDNRIWTFTLRDDAQWADGTPVTAQDFVYSWQ
HHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHH
RLVDPKTLSPFAWFAALAGITNAQAIIDGKVTPDQLGVSAVDAHTLRVQLDKPLPWFASL
HHCCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHCCEEECCEEEEEEECCCCCHHHHH
TASFAFYPVQKANVESGKDWMKPGKLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQ
HHHHEEEECCCCCCCCCHHHCCCCCEECCCHHHHHHHHCCCEEEEECCCCCCCCHHHHHH
KVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQ
HHHEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEECC
KGPTADSRVRLALSMTIDRRLMAEKVLGTGEKPAWHFTPDVTAGFTPDPSPFEQMSQEEL
CCCCCCCEEEEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHH
NAQAKTLLRAAGYGSQKPLKLTLLYNTSENHQKIAIAVASMWKKNLGVDVKLQNQEWKTY
HHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHCCCEEEEECCCHHHHH
IDSRNTGNFDVIRASWVGDYNEPSTFLSLLTSTHTGNISRFTNPTYDKILTQATMENTAE
HCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ARNADYNAAEKILTEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSRTMYIVKH
HCCCCCHHHHHHHHCCCCCCCEEEECCCEEECHHHCCCCCCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9495761; 9097039; 9278503 [H]