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The map label for this gene is tpx [H]

Identifier: 16765010

GI number: 16765010

Start: 1759693

End: 1760250

Strand: Reverse

Name: tpx [H]

Synonym: STM1667

Alternate gene names: 16765010

Gene position: 1760250-1759693 (Counterclockwise)

Preceding gene: 16765011

Following gene: 16765008

Centisome position: 36.24

GC content: 44.44

Gene sequence:

>558_bases
ATGGCTAAAATAATACAAATGTTAAAAGGAGAAGTTTTTATGACGCCAACAACAACACAGGATTATATCTCATTGGGTCA
GGAACACGCTGTCACCTTTGGCAAAACGCAACTGACCCTCAAACCCGGTATACTGGCTGAAGGCGAACCATTACCCTGCA
CAAAGGGGCTGGTGAGCCATAATTTATTACCGGGTTACTGTATCCCGGGGATAAAAAAGCAGATTATTGTCGTTCCGTCA
CTGGATACGCCAGTTTGTGAATGGCAGGTAAAAGACTATAGTGACCGCCTTAAATCAGCGGGTAGCCACTCAACCCGGGC
GGTATATGTGCTGAGTATGGATACGCCATTTGCTCAGGCCCGTTTTATTCGGGAACATGATATTCATCCCGGCATAATTT
TTGTTTCTGACTACGCTTGCCGCCAGTTTTTGGATAATTCCGGGCTGAAAATTAATGAGCTCAGTATTTTTGCCAGAGCG
TTGATAGAGTGCGATGAAAACAATGTGGTTACGCGTGTTAGTGTACCACGAGATATCACTCATCTTCCTGTTTACTAA

Upstream 100 bases:

>100_bases
AAAACTATATTAATTATTATGTCTAATATAATTCTTTTTATCACCATCATCTTATTATGGATGTTCACCTGGTTTTTTAG
CGGATTGCTAAATAATTATT

Downstream 100 bases:

>100_bases
TCACTTATATCAGCACCGCCCCTGCACAGAGAACCGAATAACCGGCAATGCAGGGGCGCAGGCATTCTCTTGTGTGCCCT
CACATTTAATATATATACTA

Product: thiol peroxidase

Products: oxidized thioredoxin; H2O [C]

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MAKIIQMLKGEVFMTPTTTQDYISLGQEHAVTFGKTQLTLKPGILAEGEPLPCTKGLVSHNLLPGYCIPGIKKQIIVVPS
LDTPVCEWQVKDYSDRLKSAGSHSTRAVYVLSMDTPFAQARFIREHDIHPGIIFVSDYACRQFLDNSGLKINELSIFARA
LIECDENNVVTRVSVPRDITHLPVY

Sequences:

>Translated_185_residues
MAKIIQMLKGEVFMTPTTTQDYISLGQEHAVTFGKTQLTLKPGILAEGEPLPCTKGLVSHNLLPGYCIPGIKKQIIVVPS
LDTPVCEWQVKDYSDRLKSAGSHSTRAVYVLSMDTPFAQARFIREHDIHPGIIFVSDYACRQFLDNSGLKINELSIFARA
LIECDENNVVTRVSVPRDITHLPVY
>Mature_184_residues
AKIIQMLKGEVFMTPTTTQDYISLGQEHAVTFGKTQLTLKPGILAEGEPLPCTKGLVSHNLLPGYCIPGIKKQIIVVPSL
DTPVCEWQVKDYSDRLKSAGSHSTRAVYVLSMDTPFAQARFIREHDIHPGIIFVSDYACRQFLDNSGLKINELSIFARAL
IECDENNVVTRVSVPRDITHLPVY

Specific function: Has antioxidant activity. Could remove peroxides or H(2)O(2) [H]

COG id: COG2077

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: 2480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018219
- InterPro:   IPR002065
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: 1.11.1.- [C]

Molecular weight: Translated: 20601; Mature: 20470

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIIQMLKGEVFMTPTTTQDYISLGQEHAVTFGKTQLTLKPGILAEGEPLPCTKGLVSH
CHHHHHHHCCCEEECCCCCHHHHHCCHHHEEEECCEEEEECCCEEECCCCCCCCHHHHHC
NLLPGYCIPGIKKQIIVVPSLDTPVCEWQVKDYSDRLKSAGSHSTRAVYVLSMDTPFAQA
CCCCCCCCCCCCEEEEEEECCCCCCEEEEECCHHHHHHCCCCCCCEEEEEEECCCCHHHH
RFIREHDIHPGIIFVSDYACRQFLDNSGLKINELSIFARALIECDENNVVTRVSVPRDIT
HHHHHCCCCCCEEEEECHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCEEEEEECCCCCC
HLPVY
CCCCC
>Mature Secondary Structure 
AKIIQMLKGEVFMTPTTTQDYISLGQEHAVTFGKTQLTLKPGILAEGEPLPCTKGLVSH
HHHHHHHCCCEEECCCCCHHHHHCCHHHEEEECCEEEEECCCEEECCCCCCCCHHHHHC
NLLPGYCIPGIKKQIIVVPSLDTPVCEWQVKDYSDRLKSAGSHSTRAVYVLSMDTPFAQA
CCCCCCCCCCCCEEEEEEECCCCCCEEEEECCHHHHHHCCCCCCCEEEEEEECCCCHHHH
RFIREHDIHPGIIFVSDYACRQFLDNSGLKINELSIFARALIECDENNVVTRVSVPRDIT
HHHHHCCCCCCEEEEECHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCEEEEEECCCCCC
HLPVY
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: reduced thioredoxin; H2O2 [C]

Specific reaction: reduced thioredoxin + H2O2 = oxidized thioredoxin + H2O [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]