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The map label for this gene is pdgL [H]

Identifier: 16764943

GI number: 16764943

Start: 1689954

End: 1690724

Strand: Reverse

Name: pdgL [H]

Synonym: STM1599

Alternate gene names: 16764943

Gene position: 1690724-1689954 (Counterclockwise)

Preceding gene: 16764945

Following gene: 16764942

Centisome position: 34.81

GC content: 47.47

Gene sequence:

>771_bases
ATGGTAAAATGCGTATCTTCTTTCCTCCTGTTCAGCCTGTTGTCCGTTCAGGCAATGTCAGCTGAAAACCATATTGATCT
CCACCAGCCAAAAGACTTTGTCGATATTACTACGGTCGCCCCCGACGTACAGGTAGACATGCGATACTTCAGTTCCCATA
ACTTTATTGGTCGCCCCATTAAAGGCTATAACGCGCCTGTTTGCCTGTTAACACGACCAGCCGCGAACGCAGTGAAGCAG
GTCGCCGATCGTTTACGCCCCTTCGGACTTACCTTAAAAATATATGATTGCTACCGTCCGCAAAGCGCAGTGAACGACTT
TATCGCGTGGGCCAAAGATCCTTCTCAAAACCAAATGAAAAACGAATTTTATCCGCAGGTAGAGAAAAATCGTCTGTTTG
AGGAAGGTTATCTTGCCGCCAGATCCGGCCACAGTCGGGGAAGTACGCTTGATCTAACGATTGTTCCACTTGACAGTAAA
ATACCAATATACGATCCCGGACGACCACTGGTGAATTGTACTGCGTCCGCGGCGCAACGCTCGCCAGATAATAGTCTGGA
TTTTGGTACCGGCTTTGACTGTTTTAGTCCGTTATCCCATCCCGATAATGTCATACTTACCGCTCAGCAACGCGCAAATA
GGTTGTTATTACAAACATTGATGCGTGATGCGGGTTTTACGCCACTGGATACTGAATGGTGGCACTTCTCTCTTACTCAT
GAACCATACCCGAACACTTGGTTTGACTTTCCCGTTAAGCAGAGACCCTGA

Upstream 100 bases:

>100_bases
GGGAAAGATGTTTATTTTAACCATCTGTTTAAGCGGTGTCCGCTAATCTTTACCTGCTCAAATACATAATCACCCCTGTG
ACTCTCGCGAGGTGTAACAT

Downstream 100 bases:

>100_bases
AACGGCGTTTTGTTGCGAAATCTAATCATTACGCCTGTTGGAAAGCACCATAACAGTTAGCAAATCATTGTTAATTTTAA
CAACTGATATACACTGCGGT

Product: periplasmic dipeptidase precursor

Products: NA

Alternate protein names: D-Ala-D-Ala dipeptidase [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MVKCVSSFLLFSLLSVQAMSAENHIDLHQPKDFVDITTVAPDVQVDMRYFSSHNFIGRPIKGYNAPVCLLTRPAANAVKQ
VADRLRPFGLTLKIYDCYRPQSAVNDFIAWAKDPSQNQMKNEFYPQVEKNRLFEEGYLAARSGHSRGSTLDLTIVPLDSK
IPIYDPGRPLVNCTASAAQRSPDNSLDFGTGFDCFSPLSHPDNVILTAQQRANRLLLQTLMRDAGFTPLDTEWWHFSLTH
EPYPNTWFDFPVKQRP

Sequences:

>Translated_256_residues
MVKCVSSFLLFSLLSVQAMSAENHIDLHQPKDFVDITTVAPDVQVDMRYFSSHNFIGRPIKGYNAPVCLLTRPAANAVKQ
VADRLRPFGLTLKIYDCYRPQSAVNDFIAWAKDPSQNQMKNEFYPQVEKNRLFEEGYLAARSGHSRGSTLDLTIVPLDSK
IPIYDPGRPLVNCTASAAQRSPDNSLDFGTGFDCFSPLSHPDNVILTAQQRANRLLLQTLMRDAGFTPLDTEWWHFSLTH
EPYPNTWFDFPVKQRP
>Mature_256_residues
MVKCVSSFLLFSLLSVQAMSAENHIDLHQPKDFVDITTVAPDVQVDMRYFSSHNFIGRPIKGYNAPVCLLTRPAANAVKQ
VADRLRPFGLTLKIYDCYRPQSAVNDFIAWAKDPSQNQMKNEFYPQVEKNRLFEEGYLAARSGHSRGSTLDLTIVPLDSK
IPIYDPGRPLVNCTASAAQRSPDNSLDFGTGFDCFSPLSHPDNVILTAQQRANRLLLQTLMRDAGFTPLDTEWWHFSLTH
EPYPNTWFDFPVKQRP

Specific function: Hydrolyzes the cellular pool of D-Ala-D-Ala dipeptides. May play a role in immunity or defense against glycopeptide antibiotics (perhaps at a moderate level) in the soil environment. Might confer vancomycin resistance to S.coelicolor [H]

COG id: COG2173

COG function: function code M; D-alanyl-D-alanine dipeptidase

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M15D family [H]

Homologues:

Organism=Escherichia coli, GI1787763, Length=207, Percent_Identity=28.9855072463768, Blast_Score=88, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009045
- InterPro:   IPR000755 [H]

Pfam domain/function: PF01427 Peptidase_M15 [H]

EC number: =3.4.13.22 [H]

Molecular weight: Translated: 28996; Mature: 28996

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKCVSSFLLFSLLSVQAMSAENHIDLHQPKDFVDITTVAPDVQVDMRYFSSHNFIGRPI
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEEHHHHHCCCCCCCCCC
KGYNAPVCLLTRPAANAVKQVADRLRPFGLTLKIYDCYRPQSAVNDFIAWAKDPSQNQMK
CCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCHHHHH
NEFYPQVEKNRLFEEGYLAARSGHSRGSTLDLTIVPLDSKIPIYDPGRPLVNCTASAAQR
HHHCCCHHHHHHHHHCCCEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEECHHHHHC
SPDNSLDFGTGFDCFSPLSHPDNVILTAQQRANRLLLQTLMRDAGFTPLDTEWWHFSLTH
CCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECC
EPYPNTWFDFPVKQRP
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVKCVSSFLLFSLLSVQAMSAENHIDLHQPKDFVDITTVAPDVQVDMRYFSSHNFIGRPI
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEEHHHHHCCCCCCCCCC
KGYNAPVCLLTRPAANAVKQVADRLRPFGLTLKIYDCYRPQSAVNDFIAWAKDPSQNQMK
CCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCHHHHH
NEFYPQVEKNRLFEEGYLAARSGHSRGSTLDLTIVPLDSKIPIYDPGRPLVNCTASAAQR
HHHCCCHHHHHHHHHCCCEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEECHHHHHC
SPDNSLDFGTGFDCFSPLSHPDNVILTAQQRANRLLLQTLMRDAGFTPLDTEWWHFSLTH
CCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECC
EPYPNTWFDFPVKQRP
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11881895; 12000953 [H]