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The map label for this gene is yncB [H]

Identifier: 16764933

GI number: 16764933

Start: 1677096

End: 1678166

Strand: Reverse

Name: yncB [H]

Synonym: STM1589

Alternate gene names: 16764933

Gene position: 1678166-1677096 (Counterclockwise)

Preceding gene: 16764936

Following gene: 16764932

Centisome position: 34.55

GC content: 53.31

Gene sequence:

>1071_bases
TTGATGGATTATGCCAGGCATGAGGAGAATAGAATGAAGCAACAGACCAACCGAAATCGTCGTTGGGTTTTGGCCTCGCG
TCCCCACGGCGCGCCGCAGATGGATAACTTCCGCCTCGAAGAAGATGACGTCGCGACGCCCGGTGAAGGGCAGGTGCTAT
TGCGTACCGTTTTTTTATCACTCGACCCTTATATGCGTGGCCGCATGAGCGATGAACCCTCTTATGCGCCGCCTGTTGAA
CCTGGCTGCGTTATGGTTGGCGGTACGGTCAGTCGCGTTGTCGCGTCGAATCATCCTGATTACCGACCAGACGAATGGGT
GTTGAGTTACAATGGTTGGCAGGATTATGACATTTCAGATGGCGAAGGGTTGGTAAAGCTGGGTGATAATCCGCAACATC
CTTCCTGGTCATTGGGTATTTTAGGAATGCCGGGGTTTACCGCCTATATGGGGTTACTGGATATCGGCCAGCCGAAAGAG
GGCGAAACGCTGGTTGTCGCCGCCGCCACCGGCCCCGTAGGCGCAACGGTTGGGCAAATTGGCAAGCTGAAGGGCTGCCG
GGTCGTGGGTATTGCTGGCGGCGCGGAAAAATGCCGTCATGCGACAGACGTTTTGGGATTTGATCTGTGCCTTGATCATC
ACGCTGATAATTTCCCACAACAGCTTGCGCAGGCCTGCCCGCAGGGTATCGATATCTATTATGAGAATGTCGGTGGTAAA
GTCTTTGACGCCGTCTTACCGCTACTGAATACGTCGGCGCGGATTCCGCTCTGCGGTCTGGTCAGCGGCTACAATGCGAC
AGCGTTGCCGGACGGTCCAGACAGACTGCCTCTGCTGATGGCGACATTACTTAAAAAGCGTATTCGTCTGCAAGGTTTTA
TCATCAACCAGGACTATGGTCACCGGATACATGAGTTTCAGCAAGAAATGGGGCGTTGGATCAAAGAAGGGAAAATACAT
TATCGGGAACAGATTACTGATGGGCTGGAAAATGCGCCAGAAGCGTTTATGGGGCTGCTGGCGGGGAAGAACTTTGGCAA
AGTCGTGATACGTTTAGCGGACGATGCGTAA

Upstream 100 bases:

>100_bases
TTCATATTTAGCGAGAAGGGGGAGAAAGTCGTTCATAAAAGCGCACAGCCTGATATCTGAGAGTGTTTAACTCCCTCAGA
AAGCTAATGTTCGACTATTA

Downstream 100 bases:

>100_bases
AGAAAAAATGGCGGCATTATGTCGCCATAAAAATGTGCAAATTTTAAAATTGCGGCTTTACTTATATTCATCATTCAGAT
CGCGGTGGGGCAGCTTATCT

Product: NADP-dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MMDYARHEENRMKQQTNRNRRWVLASRPHGAPQMDNFRLEEDDVATPGEGQVLLRTVFLSLDPYMRGRMSDEPSYAPPVE
PGCVMVGGTVSRVVASNHPDYRPDEWVLSYNGWQDYDISDGEGLVKLGDNPQHPSWSLGILGMPGFTAYMGLLDIGQPKE
GETLVVAAATGPVGATVGQIGKLKGCRVVGIAGGAEKCRHATDVLGFDLCLDHHADNFPQQLAQACPQGIDIYYENVGGK
VFDAVLPLLNTSARIPLCGLVSGYNATALPDGPDRLPLLMATLLKKRIRLQGFIINQDYGHRIHEFQQEMGRWIKEGKIH
YREQITDGLENAPEAFMGLLAGKNFGKVVIRLADDA

Sequences:

>Translated_356_residues
MMDYARHEENRMKQQTNRNRRWVLASRPHGAPQMDNFRLEEDDVATPGEGQVLLRTVFLSLDPYMRGRMSDEPSYAPPVE
PGCVMVGGTVSRVVASNHPDYRPDEWVLSYNGWQDYDISDGEGLVKLGDNPQHPSWSLGILGMPGFTAYMGLLDIGQPKE
GETLVVAAATGPVGATVGQIGKLKGCRVVGIAGGAEKCRHATDVLGFDLCLDHHADNFPQQLAQACPQGIDIYYENVGGK
VFDAVLPLLNTSARIPLCGLVSGYNATALPDGPDRLPLLMATLLKKRIRLQGFIINQDYGHRIHEFQQEMGRWIKEGKIH
YREQITDGLENAPEAFMGLLAGKNFGKVVIRLADDA
>Mature_356_residues
MMDYARHEENRMKQQTNRNRRWVLASRPHGAPQMDNFRLEEDDVATPGEGQVLLRTVFLSLDPYMRGRMSDEPSYAPPVE
PGCVMVGGTVSRVVASNHPDYRPDEWVLSYNGWQDYDISDGEGLVKLGDNPQHPSWSLGILGMPGFTAYMGLLDIGQPKE
GETLVVAAATGPVGATVGQIGKLKGCRVVGIAGGAEKCRHATDVLGFDLCLDHHADNFPQQLAQACPQGIDIYYENVGGK
VFDAVLPLLNTSARIPLCGLVSGYNATALPDGPDRLPLLMATLLKKRIRLQGFIINQDYGHRIHEFQQEMGRWIKEGKIH
YREQITDGLENAPEAFMGLLAGKNFGKVVIRLADDA

Specific function: Unknown

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226246682, Length=351, Percent_Identity=37.8917378917379, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI226246680, Length=351, Percent_Identity=37.8917378917379, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI22748929, Length=351, Percent_Identity=37.8917378917379, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI226059159, Length=338, Percent_Identity=36.6863905325444, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI226059133, Length=338, Percent_Identity=36.6863905325444, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI226056130, Length=310, Percent_Identity=34.5161290322581, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI28557745, Length=375, Percent_Identity=28, Blast_Score=108, Evalue=7e-24,
Organism=Escherichia coli, GI226510941, Length=344, Percent_Identity=85.7558139534884, Blast_Score=618, Evalue=1e-178,
Organism=Caenorhabditis elegans, GI133901712, Length=358, Percent_Identity=32.9608938547486, Blast_Score=165, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI133901710, Length=358, Percent_Identity=32.9608938547486, Blast_Score=165, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6323504, Length=370, Percent_Identity=27.027027027027, Blast_Score=123, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39196; Mature: 39196

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDYARHEENRMKQQTNRNRRWVLASRPHGAPQMDNFRLEEDDVATPGEGQVLLRTVFLS
CCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEECCCCCCCCCCCCEEHHHHHHH
LDPYMRGRMSDEPSYAPPVEPGCVMVGGTVSRVVASNHPDYRPDEWVLSYNGWQDYDISD
CCHHHHCCCCCCCCCCCCCCCCEEEECCHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCC
GEGLVKLGDNPQHPSWSLGILGMPGFTAYMGLLDIGQPKEGETLVVAAATGPVGATVGQI
CCCEEEECCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHH
GKLKGCRVVGIAGGAEKCRHATDVLGFDLCLDHHADNFPQQLAQACPQGIDIYYENVGGK
HCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCHH
VFDAVLPLLNTSARIPLCGLVSGYNATALPDGPDRLPLLMATLLKKRIRLQGFIINQDYG
HHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCC
HRIHEFQQEMGRWIKEGKIHYREQITDGLENAPEAFMGLLAGKNFGKVVIRLADDA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
>Mature Secondary Structure
MMDYARHEENRMKQQTNRNRRWVLASRPHGAPQMDNFRLEEDDVATPGEGQVLLRTVFLS
CCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEECCCCCCCCCCCCEEHHHHHHH
LDPYMRGRMSDEPSYAPPVEPGCVMVGGTVSRVVASNHPDYRPDEWVLSYNGWQDYDISD
CCHHHHCCCCCCCCCCCCCCCCEEEECCHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCC
GEGLVKLGDNPQHPSWSLGILGMPGFTAYMGLLDIGQPKEGETLVVAAATGPVGATVGQI
CCCEEEECCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHH
GKLKGCRVVGIAGGAEKCRHATDVLGFDLCLDHHADNFPQQLAQACPQGIDIYYENVGGK
HCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCHH
VFDAVLPLLNTSARIPLCGLVSGYNATALPDGPDRLPLLMATLLKKRIRLQGFIINQDYG
HHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCC
HRIHEFQQEMGRWIKEGKIHYREQITDGLENAPEAFMGLLAGKNFGKVVIRLADDA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]