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The map label for this gene is hypA [H]

Identifier: 16764876

GI number: 16764876

Start: 1607674

End: 1608015

Strand: Reverse

Name: hypA [H]

Synonym: STM1531

Alternate gene names: 16764876

Gene position: 1608015-1607674 (Counterclockwise)

Preceding gene: 16764877

Following gene: 16764873

Centisome position: 33.1

GC content: 50.58

Gene sequence:

>342_bases
ATGCATGAATTAGCCCTGGCGCAAAATATTATCGAATTGCTGGAGGAACAGGCAGTAAATCACCAGTTCAGCAAGGTAAA
GCAAGTCTGGCTGGAGATTGGCGTTATGGCCTGTGTTGAGGTGCCGGCGCTGCATTTTGGCCTGGACGTCGCCGCTCGTC
ATACCCTTGCTGACAATGCGCGTTTCCACATTACTATCGCACCGGCGCAAGGTTGGTGTCTGTCCTGTAATCAACCCTTC
ACCTCTCAAACATCCACACTCTGTTGTCCCCTTTGTCATTCAGGCAAAGTGCAGATAGATGACAGTAGCAGAATGCGCAT
TCGCGAGATCGAAGTCGAATAG

Upstream 100 bases:

>100_bases
TCGCGAACTGGCCACTATTCCACTCTCATTGTGGTCGCAACAGTTACAGGTAATTGATCCTTGTGTCGCCGTAAATATTG
TTGAATGAAGGAGCTGGCCC

Downstream 100 bases:

>100_bases
TCAACGAATAGTCAATAAAAAAGGACGCCAGAAGCGTCCTGAAATAATAAAAGAATAAATTAACAATAATAAAGGTTAAG
CAGTGACACAGTTTTGGGAA

Product: hydrogenase

Products: NA

Alternate protein names: Protein hupA [H]

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MHELALAQNIIELLEEQAVNHQFSKVKQVWLEIGVMACVEVPALHFGLDVAARHTLADNARFHITIAPAQGWCLSCNQPF
TSQTSTLCCPLCHSGKVQIDDSSRMRIREIEVE

Sequences:

>Translated_113_residues
MHELALAQNIIELLEEQAVNHQFSKVKQVWLEIGVMACVEVPALHFGLDVAARHTLADNARFHITIAPAQGWCLSCNQPF
TSQTSTLCCPLCHSGKVQIDDSSRMRIREIEVE
>Mature_113_residues
MHELALAQNIIELLEEQAVNHQFSKVKQVWLEIGVMACVEVPALHFGLDVAARHTLADNARFHITIAPAQGWCLSCNQPF
TSQTSTLCCPLCHSGKVQIDDSSRMRIREIEVE

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

Organism=Escherichia coli, GI1789365, Length=113, Percent_Identity=38.0530973451327, Blast_Score=97, Evalue=3e-22,
Organism=Escherichia coli, GI1789081, Length=114, Percent_Identity=37.719298245614, Blast_Score=87, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR020538 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 12640; Mature: 12640

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELALAQNIIELLEEQAVNHQFSKVKQVWLEIGVMACVEVPALHFGLDVAARHTLADNA
CCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCHHHHCHHHHHHHHCCCCC
RFHITIAPAQGWCLSCNQPFTSQTSTLCCPLCHSGKVQIDDSSRMRIREIEVE
EEEEEEECCCCEEEECCCCCCCCCCCEEEECCCCCEEEECCCCCEEEEEEECC
>Mature Secondary Structure
MHELALAQNIIELLEEQAVNHQFSKVKQVWLEIGVMACVEVPALHFGLDVAARHTLADNA
CCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCHHHHCHHHHHHHHCCCCC
RFHITIAPAQGWCLSCNQPFTSQTSTLCCPLCHSGKVQIDDSSRMRIREIEVE
EEEEEEECCCCEEEECCCCCCCCCCCEEEECCCCCEEEECCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]