Click here to switch to the map view.

The map label for this gene is ssaU

Identifier: 16764772

GI number: 16764772

Start: 1500431

End: 1501489

Strand: Direct

Name: ssaU

Synonym: STM1422

Alternate gene names: 16764772

Gene position: 1500431-1501489 (Clockwise)

Preceding gene: 16764771

Following gene: 16764774

Centisome position: 30.89

GC content: 39.66

Gene sequence:

>1059_bases
ATGAGCGAGAAAACAGAACAGCCTACAGAAAAGAAATTACGTGATGGCCGTAAGGAAGGGCAGGTTGTCAAAAGTATTGA
AATAACATCATTATTTCAGCTGATTGCGCTTTATTTGTATTTTCATTTCTTTACTGAAAAGATGATTTTGATACTGATTG
AGTCAATAACTTTCACATTACAATTAGTAAATAAACCATTTTCTTATGCATTAACGCAATTGAGTCATGCTTTAATAGAG
TCACTGACTTCTGCACTGCTGTTTCTGGGCGCTGGGGTAATAGTTGCTACTGTGGGTAGCGTGTTTCTTCAGGTGGGGGT
GGTTATTGCCAGCAAGGCCATTGGTTTTAAAAGCGAGCATATAAATCCGGTAAGTAATTTTAAGCAGATATTCTCTTTAC
ATAGCGTAGTAGAATTATGTAAATCCAGCCTAAAAGTTATCATGCTATCTCTTATCTTTGCCTTTTTCTTTTATTATTAT
GCCAGTACTTTTCGGGCGCTACCGTACTGTGGGTTAGCCTGTGGCGTGCTTGTGGTTTCTTCTTTAATAAAATGGTTATG
GGTAGGGGTGATGGTTTTTTATATCGTCGTTGGCATACTGGACTATTCTTTTCAATATTATAAGATTAGAAAAGATCTAA
AAATGAGTAAAGATGACGTAAAACAGGAGCATAAAGATCTGGAGGGCGACCCTCAAATGAAGACGCGGCGTCGGGAAATG
CAGAGTGAAATACAAAGTGGGAGTTTAGCTCAATCTGTTAAACAATCTGTTGCGGTAGTGCGTAATCCAACGCATATTGC
GGTTTGTCTTGGCTATCATCCCACCGATATGCCAATACCACGCGTCCTGGAAAAAGGCAGTGATGCTCAAGCTAACTATA
TTGTTAACATCGCTGAACGCAACTGCATCCCCGTTGTTGAAAATGTTGAGCTGGCCCGCTCATTATTTTTTGAAGTGGAA
CGCGGAGATAAAATTCCTGAAACGTTATTTGAACCCGTTGCAGCCTTGTTACGTATGGTGATGAAGATAGATTATGCGCA
TTCTACCGAAACACCATAA

Upstream 100 bases:

>100_bases
TTCTACTGACGCTCCTGATCTCATTCCCTTATGCTCTTCATCACTATTTGGTTGAAAGCGATAAATTTTATATTTATCTA
AAAGACTGGTTTCCATCTGT

Downstream 100 bases:

>100_bases
ATGCTTTTGGTATGCTTCTTCAGGCCACTGCGAAGGTTAAGAGGGTAATAGCGTATAGAGCAGTGCTTGACGATAAAGGT
GAGAGACTGAAAATAATCGC

Product: secretion system apparatus protein SsaU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSEKTEQPTEKKLRDGRKEGQVVKSIEITSLFQLIALYLYFHFFTEKMILILIESITFTLQLVNKPFSYALTQLSHALIE
SLTSALLFLGAGVIVATVGSVFLQVGVVIASKAIGFKSEHINPVSNFKQIFSLHSVVELCKSSLKVIMLSLIFAFFFYYY
ASTFRALPYCGLACGVLVVSSLIKWLWVGVMVFYIVVGILDYSFQYYKIRKDLKMSKDDVKQEHKDLEGDPQMKTRRREM
QSEIQSGSLAQSVKQSVAVVRNPTHIAVCLGYHPTDMPIPRVLEKGSDAQANYIVNIAERNCIPVVENVELARSLFFEVE
RGDKIPETLFEPVAALLRMVMKIDYAHSTETP

Sequences:

>Translated_352_residues
MSEKTEQPTEKKLRDGRKEGQVVKSIEITSLFQLIALYLYFHFFTEKMILILIESITFTLQLVNKPFSYALTQLSHALIE
SLTSALLFLGAGVIVATVGSVFLQVGVVIASKAIGFKSEHINPVSNFKQIFSLHSVVELCKSSLKVIMLSLIFAFFFYYY
ASTFRALPYCGLACGVLVVSSLIKWLWVGVMVFYIVVGILDYSFQYYKIRKDLKMSKDDVKQEHKDLEGDPQMKTRRREM
QSEIQSGSLAQSVKQSVAVVRNPTHIAVCLGYHPTDMPIPRVLEKGSDAQANYIVNIAERNCIPVVENVELARSLFFEVE
RGDKIPETLFEPVAALLRMVMKIDYAHSTETP
>Mature_351_residues
SEKTEQPTEKKLRDGRKEGQVVKSIEITSLFQLIALYLYFHFFTEKMILILIESITFTLQLVNKPFSYALTQLSHALIES
LTSALLFLGAGVIVATVGSVFLQVGVVIASKAIGFKSEHINPVSNFKQIFSLHSVVELCKSSLKVIMLSLIFAFFFYYYA
STFRALPYCGLACGVLVVSSLIKWLWVGVMVFYIVVGILDYSFQYYKIRKDLKMSKDDVKQEHKDLEGDPQMKTRRREMQ
SEIQSGSLAQSVKQSVAVVRNPTHIAVCLGYHPTDMPIPRVLEKGSDAQANYIVNIAERNCIPVVENVELARSLFFEVER
GDKIPETLFEPVAALLRMVMKIDYAHSTETP

Specific function: Part of a type III secretion system

COG id: COG4792

COG function: function code U; Type III secretory pathway, component EscU

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III secretion exporter family

Homologues:

Organism=Escherichia coli, GI1788188, Length=355, Percent_Identity=29.5774647887324, Blast_Score=144, Evalue=8e-36,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): SSAU_SALTY (P96069)

Other databases:

- EMBL:   X99944
- EMBL:   AE006468
- RefSeq:   NP_460387.1
- ProteinModelPortal:   P96069
- SMR:   P96069
- PRIDE:   P96069
- GeneID:   1252940
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM1422
- NMPDR:   fig|99287.1.peg.1378
- HOGENOM:   HBG529770
- OMA:   PPRQRVG
- ProtClustDB:   PRK12721
- BioCyc:   STYP99287:STM1422-MONOMER
- InterPro:   IPR006135
- InterPro:   IPR006307
- PRINTS:   PR00950
- TIGRFAMs:   TIGR01404

Pfam domain/function: PF01312 Bac_export_2

EC number: NA

Molecular weight: Translated: 39761; Mature: 39630

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd0a3de8)-; HASH(0xe1befd8)-; HASH(0xe503240)-; HASH(0xe63d494)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKTEQPTEKKLRDGRKEGQVVKSIEITSLFQLIALYLYFHFFTEKMILILIESITFTL
CCCCCCCCHHHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLVNKPFSYALTQLSHALIESLTSALLFLGAGVIVATVGSVFLQVGVVIASKAIGFKSEH
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHC
INPVSNFKQIFSLHSVVELCKSSLKVIMLSLIFAFFFYYYASTFRALPYCGLACGVLVVS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLIKWLWVGVMVFYIVVGILDYSFQYYKIRKDLKMSKDDVKQEHKDLEGDPQMKTRRREM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHH
QSEIQSGSLAQSVKQSVAVVRNPTHIAVCLGYHPTDMPIPRVLEKGSDAQANYIVNIAER
HHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCHHEEEECCC
NCIPVVENVELARSLFFEVERGDKIPETLFEPVAALLRMVMKIDYAHSTETP
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure 
SEKTEQPTEKKLRDGRKEGQVVKSIEITSLFQLIALYLYFHFFTEKMILILIESITFTL
CCCCCCCHHHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9140973; 11677609