Click here to switch to the map view.

The map label for this gene is ttrS [H]

Identifier: 16764736

GI number: 16764736

Start: 1471349

End: 1473127

Strand: Direct

Name: ttrS [H]

Synonym: STM1386

Alternate gene names: 16764736

Gene position: 1471349-1473127 (Clockwise)

Preceding gene: 16764725

Following gene: 39546316

Centisome position: 30.29

GC content: 56.77

Gene sequence:

>1779_bases
GTGAGAGGTAAAACCGTAAGGCGCCTGGCGGTGTTGGCGGCAGTAGGGCTACTTTGTCATGGCGCGTGGGCAGGGACGTG
GAATATCGGTATTTTGGCCATGCGCGGCGAGGCGTCTACGCGTAGCCACTGGCAACCGTTGGCAAAGACATTAAGCCAAC
AGCTTCCAGGCGAAACCTTTCACATCCAGCCGCTGGATCTGCATCAAATGCAGGAGGCCGTTAACCAGGGAACCGTGCAG
TTTGTGATAACCAACCCGGCGCAATTTGTCCAACTGAACAGCCATGCGCCGCTGCGCTGGTTAGCTTCCCTGCGCTCCAC
GCGCGATGGGAAAGCGGTGAGTAATGTTATTGGCAGCGTGATTTTGACCCGGCGCGATAGCGGCATCACCACGGCGCATG
ATCTCATCGGTAAGACCGTCGGCGCGATTGATGCTCAGGCGTTTGGCGGCTATTTATTAGGCTATAAAGCGCTCAGCGAC
GCGGGCTTACGCCCGGAGCGCGATTTTCATCTCCGTTTTACCGGATTTCCTGGCGATGCCTTAGTCTATATGCTGCGCGA
AAAAGCGGTGCAGGCGGCAATTGTGCCAGTGTGCCTGTTAGAAAATATGGATCAGGAAGGATTGATTAATAAAAAGGACT
TTATCGCGCTGCTTTCCCGACCGACGCCCCTGCCTTGCTTAACCAGTACGCCGTTATATCCTGACTGGTCGTTCGCGGCG
CTACCTGCGGTAAGCGATGCGCTGGCGGATCGCGTAACGCGAGCGCTATTCAACGCGCCCGCCGCCGCGTCATTTCACTG
GGGCGCGCCTGCGTCCACCAGTCAGGTGGAAGCCTTGCTGCGTGATGTTCGTCAGCACCCTCAGCAGCGTCGACTGTGGC
TGGATGTCAAAAGTTGGTTAATCCAGCACCAGCTAATGGTCGGCGGCGTGATTCTGGCGTTCTTGTTGCTCACGCTCAAT
TATATTTGGGTCATGCTGCTGGTGCGTCGACGTGGAAAGCAACTGGAACGTAATAGCGTAGTTCTTCATCAGCATGAGCG
GGCGCTGGAAACCGCCCGGCAAATGAGCGTGTTGGGTGAAATGACCTCCGGGTTTGCCCATGAGCTTAATCAGCCGCTTT
CCGCGATTCGACATTATGCCCAGGGGTGCCTGATTCGACTGCGCGCTGCAGATGAACAGCATCCCTTGCTGCCGGCGCTG
GAGCAGATTGACCAGCAGGCGCAACGCGGTGCGGATACTCTGCGTAACCTGCGTCACTGGGTCAGCCAGGCGCAGGGCAA
CCCGGTGCTAACCGAAGCGTGGAAGGCCATAGCCATTCGCGAGGCGATTGATCATGTCTGGCAATTGTTGCGTATGGCGC
AACAGTTTCCGACAGTGACTCTGCATACCGAGGTTAGCGCTGCGCTGCGCGTAACGCTGCCGTCAGTGCTGCTGGAACAG
GTGCTGGCGAATATCATTCTTAATGCGGCTCAGGCGGGCGCCACCCATTTATGGATCGTTGCTGAACGCACTGAAAACGG
CATCAGTATTGTTTTACAGGATAACGCCGGGGGAATCGATGAGGCGCTATTACGTCAGGCGTTTCAGCCGTTTATGACCA
CCCGTAAAGAGGGGATGGGCTTAGGGCTGGCGATTTGCCAGCGGCTGGTGCGGTATGGGCGGGGCGATATCAGCATCAGG
AACCAGACCGCGCCGGACGGTCTGTCGGGAACGGTGGTTACGATACATTTCTTACATGAAAATGGGGGCAGGGATGGCGA
CAATTCATCTACTGGATGA

Upstream 100 bases:

>100_bases
TTTACAGTGTAAAAATCGAGGCGGGGTGCGCTCTATTGTGGTTAACCACATACCCGGCTTGTTGTTGATCTAAAACAACA
TAATTGACAGGGATATTGGG

Downstream 100 bases:

>100_bases
TGATACGGCGGTCACTAACGCGTGCGCGTTTTTACTGGAAAGTCTGGGATATGACGTAAAATGCTGGACGCAGGGGGCGG
ATTTTTTGGCGCAGGCCAGT

Product: sensory histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MRGKTVRRLAVLAAVGLLCHGAWAGTWNIGILAMRGEASTRSHWQPLAKTLSQQLPGETFHIQPLDLHQMQEAVNQGTVQ
FVITNPAQFVQLNSHAPLRWLASLRSTRDGKAVSNVIGSVILTRRDSGITTAHDLIGKTVGAIDAQAFGGYLLGYKALSD
AGLRPERDFHLRFTGFPGDALVYMLREKAVQAAIVPVCLLENMDQEGLINKKDFIALLSRPTPLPCLTSTPLYPDWSFAA
LPAVSDALADRVTRALFNAPAAASFHWGAPASTSQVEALLRDVRQHPQQRRLWLDVKSWLIQHQLMVGGVILAFLLLTLN
YIWVMLLVRRRGKQLERNSVVLHQHERALETARQMSVLGEMTSGFAHELNQPLSAIRHYAQGCLIRLRAADEQHPLLPAL
EQIDQQAQRGADTLRNLRHWVSQAQGNPVLTEAWKAIAIREAIDHVWQLLRMAQQFPTVTLHTEVSAALRVTLPSVLLEQ
VLANIILNAAQAGATHLWIVAERTENGISIVLQDNAGGIDEALLRQAFQPFMTTRKEGMGLGLAICQRLVRYGRGDISIR
NQTAPDGLSGTVVTIHFLHENGGRDGDNSSTG

Sequences:

>Translated_592_residues
MRGKTVRRLAVLAAVGLLCHGAWAGTWNIGILAMRGEASTRSHWQPLAKTLSQQLPGETFHIQPLDLHQMQEAVNQGTVQ
FVITNPAQFVQLNSHAPLRWLASLRSTRDGKAVSNVIGSVILTRRDSGITTAHDLIGKTVGAIDAQAFGGYLLGYKALSD
AGLRPERDFHLRFTGFPGDALVYMLREKAVQAAIVPVCLLENMDQEGLINKKDFIALLSRPTPLPCLTSTPLYPDWSFAA
LPAVSDALADRVTRALFNAPAAASFHWGAPASTSQVEALLRDVRQHPQQRRLWLDVKSWLIQHQLMVGGVILAFLLLTLN
YIWVMLLVRRRGKQLERNSVVLHQHERALETARQMSVLGEMTSGFAHELNQPLSAIRHYAQGCLIRLRAADEQHPLLPAL
EQIDQQAQRGADTLRNLRHWVSQAQGNPVLTEAWKAIAIREAIDHVWQLLRMAQQFPTVTLHTEVSAALRVTLPSVLLEQ
VLANIILNAAQAGATHLWIVAERTENGISIVLQDNAGGIDEALLRQAFQPFMTTRKEGMGLGLAICQRLVRYGRGDISIR
NQTAPDGLSGTVVTIHFLHENGGRDGDNSSTG
>Mature_592_residues
MRGKTVRRLAVLAAVGLLCHGAWAGTWNIGILAMRGEASTRSHWQPLAKTLSQQLPGETFHIQPLDLHQMQEAVNQGTVQ
FVITNPAQFVQLNSHAPLRWLASLRSTRDGKAVSNVIGSVILTRRDSGITTAHDLIGKTVGAIDAQAFGGYLLGYKALSD
AGLRPERDFHLRFTGFPGDALVYMLREKAVQAAIVPVCLLENMDQEGLINKKDFIALLSRPTPLPCLTSTPLYPDWSFAA
LPAVSDALADRVTRALFNAPAAASFHWGAPASTSQVEALLRDVRQHPQQRRLWLDVKSWLIQHQLMVGGVILAFLLLTLN
YIWVMLLVRRRGKQLERNSVVLHQHERALETARQMSVLGEMTSGFAHELNQPLSAIRHYAQGCLIRLRAADEQHPLLPAL
EQIDQQAQRGADTLRNLRHWVSQAQGNPVLTEAWKAIAIREAIDHVWQLLRMAQQFPTVTLHTEVSAALRVTLPSVLLEQ
VLANIILNAAQAGATHLWIVAERTENGISIVLQDNAGGIDEALLRQAFQPFMTTRKEGMGLGLAICQRLVRYGRGDISIR
NQTAPDGLSGTVVTIHFLHENGGRDGDNSSTG

Specific function: Putative oxygen sensor; modulates the activity of fixJ, a transcriptional activator of nitrogen fixation fixK gene. FixL probably acts as a kinase that phosphorylates fixJ [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=30.6306306306306, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1790436, Length=270, Percent_Identity=28.5185185185185, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65240; Mature: 65240

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGKTVRRLAVLAAVGLLCHGAWAGTWNIGILAMRGEASTRSHWQPLAKTLSQQLPGETF
CCCHHHHHHHHHHHHHHHHHCCCCCEECEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEE
HIQPLDLHQMQEAVNQGTVQFVITNPAQFVQLNSHAPLRWLASLRSTRDGKAVSNVIGSV
EECCCCHHHHHHHHCCCCEEEEEECCHHEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHH
ILTRRDSGITTAHDLIGKTVGAIDAQAFGGYLLGYKALSDAGLRPERDFHLRFTGFPGDA
HHEECCCCCCHHHHHHHHHHHHCHHHHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCHHH
LVYMLREKAVQAAIVPVCLLENMDQEGLINKKDFIALLSRPTPLPCLTSTPLYPDWSFAA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
LPAVSDALADRVTRALFNAPAAASFHWGAPASTSQVEALLRDVRQHPQQRRLWLDVKSWL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHH
IQHQLMVGGVILAFLLLTLNYIWVMLLVRRRGKQLERNSVVLHQHERALETARQMSVLGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
MTSGFAHELNQPLSAIRHYAQGCLIRLRAADEQHPLLPALEQIDQQAQRGADTLRNLRHW
HHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VSQAQGNPVLTEAWKAIAIREAIDHVWQLLRMAQQFPTVTLHTEVSAALRVTLPSVLLEQ
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHH
VLANIILNAAQAGATHLWIVAERTENGISIVLQDNAGGIDEALLRQAFQPFMTTRKEGMG
HHHHHHHHHHHCCCEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
LGLAICQRLVRYGRGDISIRNQTAPDGLSGTVVTIHFLHENGGRDGDNSSTG
CHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MRGKTVRRLAVLAAVGLLCHGAWAGTWNIGILAMRGEASTRSHWQPLAKTLSQQLPGETF
CCCHHHHHHHHHHHHHHHHHCCCCCEECEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEE
HIQPLDLHQMQEAVNQGTVQFVITNPAQFVQLNSHAPLRWLASLRSTRDGKAVSNVIGSV
EECCCCHHHHHHHHCCCCEEEEEECCHHEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHH
ILTRRDSGITTAHDLIGKTVGAIDAQAFGGYLLGYKALSDAGLRPERDFHLRFTGFPGDA
HHEECCCCCCHHHHHHHHHHHHCHHHHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCHHH
LVYMLREKAVQAAIVPVCLLENMDQEGLINKKDFIALLSRPTPLPCLTSTPLYPDWSFAA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
LPAVSDALADRVTRALFNAPAAASFHWGAPASTSQVEALLRDVRQHPQQRRLWLDVKSWL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHH
IQHQLMVGGVILAFLLLTLNYIWVMLLVRRRGKQLERNSVVLHQHERALETARQMSVLGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
MTSGFAHELNQPLSAIRHYAQGCLIRLRAADEQHPLLPALEQIDQQAQRGADTLRNLRHW
HHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VSQAQGNPVLTEAWKAIAIREAIDHVWQLLRMAQQFPTVTLHTEVSAALRVTLPSVLLEQ
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHH
VLANIILNAAQAGATHLWIVAERTENGISIVLQDNAGGIDEALLRQAFQPFMTTRKEGMG
HHHHHHHHHHHCCCEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
LGLAICQRLVRYGRGDISIRNQTAPDGLSGTVVTIHFLHENGGRDGDNSSTG
CHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2842062; 11481432; 8432704 [H]