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The map label for this gene is orf48 [H]

Identifier: 16764729

GI number: 16764729

Start: 1461740

End: 1463083

Strand: Reverse

Name: orf48 [H]

Synonym: STM1379

Alternate gene names: 16764729

Gene position: 1463083-1461740 (Counterclockwise)

Preceding gene: 16764730

Following gene: 16764728

Centisome position: 30.12

GC content: 50.82

Gene sequence:

>1344_bases
ATGAAAAAAGTCAAAAAATTGTCTCTTACCGATTTAGTGCTTTATGGTCTGGTGTTTATGGTGCCTATCGCGCCAGTCTC
TCTTTATGGCGTCGTTTATAATCTTTCGCACGGTATGGTTGCGCTGGTTTATATTATTGGCGCGATCGCGATGTTTTTTA
CCGCGTACAGCTACTCTACCTTATCGCAGCATATCTCCTCGTCGGGTTCGGCCTATGCGTATGCTGGCGTATGCATTAAT
CCCGCCGTAGGGTTTCTGACCGGATGGATATTACTGCTGGATTATCTTTTGTTCCCTACGCTCGTGGCAGTGCTGGGCGG
CGTCGCGGTCCACGCTATTTTACCGCAAATCCCGGTCTGGGTCTGGCCGTTGATTTATGTGGCTATTGGCACCGGAGTCA
ACTATCTCGGGATACAGCAAACGGCGAAATTCGATAAGTTACTGGTCTTTATTCAACTCGGTATTCTGGCGATTTTCGTG
CTACTCATTGTCCGTCTGATGCTGCTGGACAGTAGTCAGATAACGCTTTCCTTCCGGCCTTTTTTCGATTCACAGTGGTT
CACCCCAGGGCTCATCGCGACGGCGATTTCGGTGGCTGCGCTGAACTTTCTCGGCTTTGACGCTATCAGTACATTAAGTG
AAGAAAGCGAAGGCGGGGGACGCGCCGTCAGTAAAGCAACGCTGTTGGCGTTAGTTTTGGCGACGGTACTGTTTATTATC
GTTGTGGCGTTTGCGGCGTTCGCCACCGGTAACGTCGACCGCTTCGCGGAAGGTAATGCGACGAATGAAGCATTTTTCAC
CATTGCCGGCAACGTTGGCGGTATCTGGCTCAAAGTGGCGTTTTCCATCATTGTGGCGTTTGTGTGCGCCGTCGGCAACA
TTATTACCGCGCAAACGGCGGTGTCCAGAGTGTTATTTTCAATGGGGCGCGACCGAATGTTGCCCGCCTTCCTCGCTCAC
GTCCATACCACGCGTAAAACGCCGGATTATGCCATTCTGTTTACCGGCGGCGTCACCCTGCTGCTCAGCTACCTGTTTTC
CGGCAAGATTGAATCTATCTCCACGCTGGTGAACTTTGGCGCGCTTTTCGCTTTTTTTGTCGTGAACCTGTGTGTGTTTA
TCCTGTTCAATTTCCGGATGAAAGCCCAGCGGCGCATTTTCGCCCATGTCATTTCGCCGATCATGGGGATGATCGTCATC
GGCTACGTCTGTTTAAACATGAACATTCACGCTCTGATACTCGGAATTAGCTGGGCGGCCATCGGGATAGCGATTCTGTG
CTATCGAAAAGCACACAACCAAAACATCGCCATCGACCTGGAAGGCAAAAAGTTGCTCGATTGA

Upstream 100 bases:

>100_bases
CAGCAGCCATAACCCGCATGAAGAAAATATCGCGCCCTGCCTCGCAGCGGTAAGCGCGTTTTTACGCGATCTGGCATAAA
AAGCCATTAAGGTATTTATC

Downstream 100 bases:

>100_bases
CATTATGCGCAACAACACCCGCTGTTGCGCAACGCCGCCCCTGTTCGGGCGGCGTTATCGCCAGCGACATCGTAAACAGC
GTAATAACAAACCGTTGTGG

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MKKVKKLSLTDLVLYGLVFMVPIAPVSLYGVVYNLSHGMVALVYIIGAIAMFFTAYSYSTLSQHISSSGSAYAYAGVCIN
PAVGFLTGWILLLDYLLFPTLVAVLGGVAVHAILPQIPVWVWPLIYVAIGTGVNYLGIQQTAKFDKLLVFIQLGILAIFV
LLIVRLMLLDSSQITLSFRPFFDSQWFTPGLIATAISVAALNFLGFDAISTLSEESEGGGRAVSKATLLALVLATVLFII
VVAFAAFATGNVDRFAEGNATNEAFFTIAGNVGGIWLKVAFSIIVAFVCAVGNIITAQTAVSRVLFSMGRDRMLPAFLAH
VHTTRKTPDYAILFTGGVTLLLSYLFSGKIESISTLVNFGALFAFFVVNLCVFILFNFRMKAQRRIFAHVISPIMGMIVI
GYVCLNMNIHALILGISWAAIGIAILCYRKAHNQNIAIDLEGKKLLD

Sequences:

>Translated_447_residues
MKKVKKLSLTDLVLYGLVFMVPIAPVSLYGVVYNLSHGMVALVYIIGAIAMFFTAYSYSTLSQHISSSGSAYAYAGVCIN
PAVGFLTGWILLLDYLLFPTLVAVLGGVAVHAILPQIPVWVWPLIYVAIGTGVNYLGIQQTAKFDKLLVFIQLGILAIFV
LLIVRLMLLDSSQITLSFRPFFDSQWFTPGLIATAISVAALNFLGFDAISTLSEESEGGGRAVSKATLLALVLATVLFII
VVAFAAFATGNVDRFAEGNATNEAFFTIAGNVGGIWLKVAFSIIVAFVCAVGNIITAQTAVSRVLFSMGRDRMLPAFLAH
VHTTRKTPDYAILFTGGVTLLLSYLFSGKIESISTLVNFGALFAFFVVNLCVFILFNFRMKAQRRIFAHVISPIMGMIVI
GYVCLNMNIHALILGISWAAIGIAILCYRKAHNQNIAIDLEGKKLLD
>Mature_447_residues
MKKVKKLSLTDLVLYGLVFMVPIAPVSLYGVVYNLSHGMVALVYIIGAIAMFFTAYSYSTLSQHISSSGSAYAYAGVCIN
PAVGFLTGWILLLDYLLFPTLVAVLGGVAVHAILPQIPVWVWPLIYVAIGTGVNYLGIQQTAKFDKLLVFIQLGILAIFV
LLIVRLMLLDSSQITLSFRPFFDSQWFTPGLIATAISVAALNFLGFDAISTLSEESEGGGRAVSKATLLALVLATVLFII
VVAFAAFATGNVDRFAEGNATNEAFFTIAGNVGGIWLKVAFSIIVAFVCAVGNIITAQTAVSRVLFSMGRDRMLPAFLAH
VHTTRKTPDYAILFTGGVTLLLSYLFSGKIESISTLVNFGALFAFFVVNLCVFILFNFRMKAQRRIFAHVISPIMGMIVI
GYVCLNMNIHALILGISWAAIGIAILCYRKAHNQNIAIDLEGKKLLD

Specific function: Imports putrescine [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI115648063, Length=371, Percent_Identity=25.3369272237197, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI115648022, Length=371, Percent_Identity=25.3369272237197, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI7657683, Length=367, Percent_Identity=23.9782016348774, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI186910308, Length=373, Percent_Identity=24.9329758713137, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI186910306, Length=373, Percent_Identity=24.9329758713137, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI186910304, Length=373, Percent_Identity=24.9329758713137, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081869, Length=430, Percent_Identity=34.4186046511628, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI87082023, Length=439, Percent_Identity=31.2072892938497, Blast_Score=197, Evalue=8e-52,
Organism=Escherichia coli, GI87081708, Length=414, Percent_Identity=22.7053140096618, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32566699, Length=347, Percent_Identity=23.6311239193084, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=415, Percent_Identity=24.0963855421687, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17533459, Length=370, Percent_Identity=23.5135135135135, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24666159, Length=416, Percent_Identity=24.2788461538462, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221512776, Length=416, Percent_Identity=24.2788461538462, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24667468, Length=418, Percent_Identity=24.1626794258373, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48399; Mature: 48399

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVKKLSLTDLVLYGLVFMVPIAPVSLYGVVYNLSHGMVALVYIIGAIAMFFTAYSYST
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LSQHISSSGSAYAYAGVCINPAVGFLTGWILLLDYLLFPTLVAVLGGVAVHAILPQIPVW
HHHHHHCCCCEEEEECEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VWPLIYVAIGTGVNYLGIQQTAKFDKLLVFIQLGILAIFVLLIVRLMLLDSSQITLSFRP
HHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
FFDSQWFTPGLIATAISVAALNFLGFDAISTLSEESEGGGRAVSKATLLALVLATVLFII
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
VVAFAAFATGNVDRFAEGNATNEAFFTIAGNVGGIWLKVAFSIIVAFVCAVGNIITAQTA
HHHHHHHHCCCCHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
VSRVLFSMGRDRMLPAFLAHVHTTRKTPDYAILFTGGVTLLLSYLFSGKIESISTLVNFG
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCCHHHHHHHHHHH
ALFAFFVVNLCVFILFNFRMKAQRRIFAHVISPIMGMIVIGYVCLNMNIHALILGISWAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IGIAILCYRKAHNQNIAIDLEGKKLLD
HHHHHHHHHHHCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKKVKKLSLTDLVLYGLVFMVPIAPVSLYGVVYNLSHGMVALVYIIGAIAMFFTAYSYST
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LSQHISSSGSAYAYAGVCINPAVGFLTGWILLLDYLLFPTLVAVLGGVAVHAILPQIPVW
HHHHHHCCCCEEEEECEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VWPLIYVAIGTGVNYLGIQQTAKFDKLLVFIQLGILAIFVLLIVRLMLLDSSQITLSFRP
HHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
FFDSQWFTPGLIATAISVAALNFLGFDAISTLSEESEGGGRAVSKATLLALVLATVLFII
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
VVAFAAFATGNVDRFAEGNATNEAFFTIAGNVGGIWLKVAFSIIVAFVCAVGNIITAQTA
HHHHHHHHCCCCHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
VSRVLFSMGRDRMLPAFLAHVHTTRKTPDYAILFTGGVTLLLSYLFSGKIESISTLVNFG
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCCHHHHHHHHHHH
ALFAFFVVNLCVFILFNFRMKAQRRIFAHVISPIMGMIVIGYVCLNMNIHALILGISWAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IGIAILCYRKAHNQNIAIDLEGKKLLD
HHHHHHHHHHHCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]