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The map label for this gene is argD [H]

Identifier: 16764654

GI number: 16764654

Start: 1382194

End: 1383420

Strand: Direct

Name: argD [H]

Synonym: STM1303

Alternate gene names: 16764654

Gene position: 1382194-1383420 (Clockwise)

Preceding gene: 16764651

Following gene: 16764655

Centisome position: 28.46

GC content: 56.23

Gene sequence:

>1227_bases
ATGTCTCTGTCAGTTACGCGCGAAAACTTTGATGAATGGATGGTGCCGGTATACGTTCCCGCGCCTTTTATTCCTGTACG
CGGAGAAGGCTCACGCCTGTGGGATCAGCAGGGGAAAGAGTATATTGATTTTGCTGGTGGGATCGCGGTCAACGCCTTGG
GACATGCGCATCCGGCGCTGCGCGAGGCGTTAAATGAACAGGCGAATCGCTTCTGGCATATCGGGAACGGTTACACCAAT
GAACCGGCGCTGCGACTGGCGAAAAAACTGATCGACGCGACCTTCGCCGAACGCGTTTTCTTTTGTAATTCAGGCGCTGA
AGCAAATGAAGCTGCATTAAAACTGGCGCGCAAATATGCCCACGATCGTGTCGGCAACCATAAAAGCGGCATTGTGGCCT
TTAAAAACGCGTTCCATGGCCGCACGCTCTTTACCGTCAGCGCTGGCGGTCAACCCACCTATTCACAGGACTTTGCGCCG
CTGCCGCCGGATATTCGTCATGCAGCCTATAACGATCTGAACTCCGCCAGCGCGCTCATTGATGACAATACCTGCGCCGT
GATCGTAGAACCGGTGCAGGGCGAGGGCGGCGTGATCCCCGCCACGAAAGCTTTTTTGCAGGGGCTGCGTGAATTGTGCG
ACCGGCATCAGGCGTTACTGATTTTTGATGAGGTGCAGACGGGCGTCGGACGTACCGGCGAACTGTATGCATATATGCAT
TATGGCGTTACGCCCGATATCCTGACGACCGCTAAAGCGTTGGGCGGCGGCTTCCCGATCGGCGCGATGCTGACCACGCA
AGACTATGCCAGCGTCATGACGCCAGGCACGCATGGCACCACCTACGGCGGTAATCCGCTGGCGACGGCAGTTGCCGGAA
AAGTACTGGATATCATCAATACGCCGGAGATGCAAAACGGCGTCAGACAGCGCCACGATGCGTTTATTGAACGTCTAAAT
ACCCTTAATGTGCGTTTTGGCATGTTCAGTGAAATTCGCGGGCTGGGGCTACTGCTTGGCTGTGTGCTACAGACGGAGTT
TGCCGGAAAAGCCAAACTCATCGCCCAGGAAGCGGCAAAAGCAGGCGTGATGGTGCTCATTGCCGGTGGCGACGTGGTGC
GTTTTGCGCCAGCGTTAAATGTGAGCGACGAGGAGATAGCCACCGGGCTTGATCGTTTTGCCCTGGCGTGCGAACGCCTT
CAGACGGGAGGCGTACCATGCGGGTGA

Upstream 100 bases:

>100_bases
TTAACGCTGGCTGGCACGAATGCTGCAATCTACATTTACAGCGCAAACACTCATATTAATTAACATATAAATAACTTTAT
TTTTACCAAAAGAGGTCGCT

Downstream 100 bases:

>100_bases
TTCGTCCTGTCGAACATGCGGATATCGCCGCGCTGATGCAGCTTGCAGGCAAAACGGGCGGCGGCTTAACCTCGCTACCG
GCAAATGAAGCGACGCTGGC

Product: bifunctional succinylornithine transaminase/acetylornithine transaminase

Products: NA

Alternate protein names: Succinylornithine aminotransferase [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MSLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPALREALNEQANRFWHIGNGYTN
EPALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYAHDRVGNHKSGIVAFKNAFHGRTLFTVSAGGQPTYSQDFAP
LPPDIRHAAYNDLNSASALIDDNTCAVIVEPVQGEGGVIPATKAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMH
YGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIINTPEMQNGVRQRHDAFIERLN
TLNVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAKAGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERL
QTGGVPCG

Sequences:

>Translated_408_residues
MSLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPALREALNEQANRFWHIGNGYTN
EPALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYAHDRVGNHKSGIVAFKNAFHGRTLFTVSAGGQPTYSQDFAP
LPPDIRHAAYNDLNSASALIDDNTCAVIVEPVQGEGGVIPATKAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMH
YGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIINTPEMQNGVRQRHDAFIERLN
TLNVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAKAGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERL
QTGGVPCG
>Mature_407_residues
SLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPALREALNEQANRFWHIGNGYTNE
PALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYAHDRVGNHKSGIVAFKNAFHGRTLFTVSAGGQPTYSQDFAPL
PPDIRHAAYNDLNSASALIDDNTCAVIVEPVQGEGGVIPATKAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMHY
GVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIINTPEMQNGVRQRHDAFIERLNT
LNVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAKAGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERLQ
TGGVPCG

Specific function: Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=378, Percent_Identity=34.3915343915344, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI284507298, Length=293, Percent_Identity=36.8600682593857, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI13994255, Length=443, Percent_Identity=27.0880361173815, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI37574042, Length=422, Percent_Identity=27.2511848341232, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI226442705, Length=422, Percent_Identity=27.4881516587678, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI24119277, Length=430, Percent_Identity=26.2790697674419, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI226442709, Length=387, Percent_Identity=27.6485788113695, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI188536080, Length=428, Percent_Identity=25, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI38679950, Length=428, Percent_Identity=25, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI38679946, Length=428, Percent_Identity=25, Blast_Score=99, Evalue=7e-21,
Organism=Escherichia coli, GI1788044, Length=404, Percent_Identity=84.4059405940594, Blast_Score=726, Evalue=0.0,
Organism=Escherichia coli, GI1789759, Length=397, Percent_Identity=62.4685138539043, Blast_Score=525, Evalue=1e-150,
Organism=Escherichia coli, GI145693181, Length=390, Percent_Identity=35.3846153846154, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1789016, Length=398, Percent_Identity=32.9145728643216, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1787560, Length=394, Percent_Identity=34.5177664974619, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1786349, Length=312, Percent_Identity=33.6538461538462, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1786991, Length=316, Percent_Identity=33.8607594936709, Blast_Score=136, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI25144271, Length=378, Percent_Identity=34.1269841269841, Blast_Score=231, Evalue=5e-61,
Organism=Caenorhabditis elegans, GI32564660, Length=436, Percent_Identity=28.4403669724771, Blast_Score=181, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI25144274, Length=276, Percent_Identity=34.4202898550725, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=362, Percent_Identity=28.7292817679558, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=372, Percent_Identity=25.2688172043011, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71981843, Length=164, Percent_Identity=31.0975609756098, Blast_Score=91, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6324432, Length=395, Percent_Identity=41.5189873417722, Blast_Score=288, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6323470, Length=422, Percent_Identity=33.8862559241706, Blast_Score=219, Evalue=4e-58,
Organism=Saccharomyces cerevisiae, GI6324386, Length=318, Percent_Identity=30.5031446540881, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6321456, Length=363, Percent_Identity=25.8953168044077, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21357415, Length=379, Percent_Identity=34.0369393139842, Blast_Score=221, Evalue=8e-58,
Organism=Drosophila melanogaster, GI28574759, Length=446, Percent_Identity=29.8206278026906, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI161085790, Length=441, Percent_Identity=29.7052154195011, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI21356575, Length=363, Percent_Identity=30.3030303030303, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI281366494, Length=429, Percent_Identity=24.2424242424242, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24667139, Length=429, Percent_Identity=24.2424242424242, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24667143, Length=429, Percent_Identity=24.2424242424242, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.81 [H]

Molecular weight: Translated: 43832; Mature: 43701

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPAL
CCCCCCHHCHHHCEEEEEECCCEEEECCCCCHHHHHCCCHHHHHCCCCCEEHHHCCCHHH
REALNEQANRFWHIGNGYTNEPALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYA
HHHHHHHHHCEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHH
HDRVGNHKSGIVAFKNAFHGRTLFTVSAGGQPTYSQDFAPLPPDIRHAAYNDLNSASALI
HHHCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEE
DDNTCAVIVEPVQGEGGVIPATKAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMH
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCEEEEEE
YGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIIN
CCCCHHHHHHHHHHCCCCCCCEEEECHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHC
TPEMQNGVRQRHDAFIERLNTLNVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAK
CCHHHHHHHHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
AGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERLQTGGVPCG
CCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPAL
CCCCCHHCHHHCEEEEEECCCEEEECCCCCHHHHHCCCHHHHHCCCCCEEHHHCCCHHH
REALNEQANRFWHIGNGYTNEPALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYA
HHHHHHHHHCEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHH
HDRVGNHKSGIVAFKNAFHGRTLFTVSAGGQPTYSQDFAPLPPDIRHAAYNDLNSASALI
HHHCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEE
DDNTCAVIVEPVQGEGGVIPATKAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMH
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCEEEEEE
YGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIIN
CCCCHHHHHHHHHHCCCCCCCEEEECHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHC
TPEMQNGVRQRHDAFIERLNTLNVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAK
CCHHHHHHHHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
AGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERLQTGGVPCG
CCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA