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The map label for this gene is nudG [H]

Identifier: 16764652

GI number: 16764652

Start: 1380453

End: 1380869

Strand: Reverse

Name: nudG [H]

Synonym: STM1301

Alternate gene names: 16764652

Gene position: 1380869-1380453 (Counterclockwise)

Preceding gene: 16764653

Following gene: 16764650

Centisome position: 28.43

GC content: 57.31

Gene sequence:

>417_bases
ATGATAAAAAAACTCGATGTTGTTGCCGCCATCATTGAATGCGACGGCAAAATTCTGCTGGCCCAGCGCCCAGCTCATGC
GGATCAAGCCGGTTTATGGGAGTTTGCCGGCGGTAAAGTCGAACCCGGCGAAACCCAGCCGCAGGCGCTTATCCGCGAGC
TACGCGAAGAGTTAGGGATTGACGCCACGCCCGGCGTCTATATCGCCAGCCATCAACGCGACGTGTCTGGCCGACGAATT
CATTTGCACGCCTGGCATGTGCCTGCGTTTAACGGTCTGATACGTGCGCTGGAACATCAGGCATTAGCCTGGTGTACGCC
GGAAGAGGCGCTGGAGTACCCCCTCGCCCCGGCGGATATTCCGCTATTGCAGGCGTTTATAGCTTTACGCGACGCCAGAC
TAACGGATTCGTGCTGA

Upstream 100 bases:

>100_bases
GCCGGTCTGGGCGACGTTTCGTGTTTGATTCCGCTTTCTGATTAACCGTAAGGCCGGGATAGCGCGACGCTTCCCGGCAG
GAATAACGACCTTAACGACA

Downstream 100 bases:

>100_bases
TGGTTTTTTCGTCACGCTGGCACTGGAGCAAGACGCCTTCCACTTTTATTACCGCGCCTTCGGAGTAATTCTGATCCTGG
TAAACGCAGCACTGAATGCA

Product: pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MIKKLDVVAAIIECDGKILLAQRPAHADQAGLWEFAGGKVEPGETQPQALIRELREELGIDATPGVYIASHQRDVSGRRI
HLHAWHVPAFNGLIRALEHQALAWCTPEEALEYPLAPADIPLLQAFIALRDARLTDSC

Sequences:

>Translated_138_residues
MIKKLDVVAAIIECDGKILLAQRPAHADQAGLWEFAGGKVEPGETQPQALIRELREELGIDATPGVYIASHQRDVSGRRI
HLHAWHVPAFNGLIRALEHQALAWCTPEEALEYPLAPADIPLLQAFIALRDARLTDSC
>Mature_138_residues
MIKKLDVVAAIIECDGKILLAQRPAHADQAGLWEFAGGKVEPGETQPQALIRELREELGIDATPGVYIASHQRDVSGRRI
HLHAWHVPAFNGLIRALEHQALAWCTPEEALEYPLAPADIPLLQAFIALRDARLTDSC

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=135, Percent_Identity=77.037037037037, Blast_Score=212, Evalue=6e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 15188; Mature: 15188

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKLDVVAAIIECDGKILLAQRPAHADQAGLWEFAGGKVEPGETQPQALIRELREELGI
CCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHCC
DATPGVYIASHQRDVSGRRIHLHAWHVPAFNGLIRALEHQALAWCTPEEALEYPLAPADI
CCCCCEEEECCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHEECCCHHHHCCCCCCCCH
PLLQAFIALRDARLTDSC
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIKKLDVVAAIIECDGKILLAQRPAHADQAGLWEFAGGKVEPGETQPQALIRELREELGI
CCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHCC
DATPGVYIASHQRDVSGRRIHLHAWHVPAFNGLIRALEHQALAWCTPEEALEYPLAPADI
CCCCCEEEECCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHEECCCHHHHCCCCCCCCH
PLLQAFIALRDARLTDSC
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]