Click here to switch to the map view.

The map label for this gene is nikD [H]

Identifier: 16764610

GI number: 16764610

Start: 1342527

End: 1343324

Strand: Direct

Name: nikD [H]

Synonym: STM1258

Alternate gene names: 16764610

Gene position: 1342527-1343324 (Clockwise)

Preceding gene: 16764609

Following gene: 16764611

Centisome position: 27.64

GC content: 55.39

Gene sequence:

>798_bases
ATGCTGAGTTTACAACAGGTTACGCTGGAAAGCGCGCGTTATCGCTGGTATGGCGCGAGACGCTGGTCGCCGTTATTACA
GAATGTCTCTTTTGATATCGCGCCCGGCGAAATGGTGGCATTGGTTGGCGGCAGCGGGGAGGGCAAAAGTCTGCTGCTGC
AATGCCTGCTCGATCTGCTGCCGGAAAATTTACGCTTTCGGGGGGAGATTACGCTTGATGGCAACCGGCTGGACAGACAT
ACCATCAGGCAGCTTAGGGGCAATACGTTTAGCTACGTGCCGCAGGGGGTACAGGCGCTTAATCCCATGCTGAATATCAG
AAAACATTTGAACAGAGCATGTCATCTGACCGGACGCGCCTGGGATGAGACGCAAATGGTACAGCTATTACAGCAAAGCG
ATCTTGAACCGACAGTCCTGGAACGCTTTCCCCGCCAGCTCTCCGGTGGGATGGCTAAACGAATTCTGGCGTGCCACGCC
TCGCTTAGCCAGGCACGTTATATCCTCGCGGATGAGATCACCGCCTGGCTTGATACCGCACTGGCAAACCAGTTGCTCGA
GCACTTGCGAGGCCTCTGCGAGCGGGGATGCGGCGTGCTGTGGGTGACTCATGACCTGCTGCTGGCGGCGCGGTATGCCG
ATCGCATTGTGGCGCTGCATCAGGGTTATATCACGGACAATATCCGCTGCGAGCAGTTACAGCCGGAAGAGATGAGTGAA
CCGTTAAAACGGCAATGGCAAGCATTGCCTGAACTAAACCCGTTATTTATGCCGACCGGAGAGGGAATAGAATGCTGA

Upstream 100 bases:

>100_bases
GGTGGCTGGTGCTATTTCCCGGCCTAATGTTATTCACGCTGGTGATGCTCTTCGATCAGTTTGCGCGCGCCATTCAGCGG
CTGTGGCTAAGGAGTGACGT

Downstream 100 bases:

>100_bases
GCTGCCGCGACCTCGTTATTCGTCAGGGCGGGAAAGTCTTATGGCAGAACCTGACGTTTACGATTTCTGCCGGTGAACGG
GTAGGAATTCATGCGCCAAG

Product: ABC-type transport system ATPase component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MLSLQQVTLESARYRWYGARRWSPLLQNVSFDIAPGEMVALVGGSGEGKSLLLQCLLDLLPENLRFRGEITLDGNRLDRH
TIRQLRGNTFSYVPQGVQALNPMLNIRKHLNRACHLTGRAWDETQMVQLLQQSDLEPTVLERFPRQLSGGMAKRILACHA
SLSQARYILADEITAWLDTALANQLLEHLRGLCERGCGVLWVTHDLLLAARYADRIVALHQGYITDNIRCEQLQPEEMSE
PLKRQWQALPELNPLFMPTGEGIEC

Sequences:

>Translated_265_residues
MLSLQQVTLESARYRWYGARRWSPLLQNVSFDIAPGEMVALVGGSGEGKSLLLQCLLDLLPENLRFRGEITLDGNRLDRH
TIRQLRGNTFSYVPQGVQALNPMLNIRKHLNRACHLTGRAWDETQMVQLLQQSDLEPTVLERFPRQLSGGMAKRILACHA
SLSQARYILADEITAWLDTALANQLLEHLRGLCERGCGVLWVTHDLLLAARYADRIVALHQGYITDNIRCEQLQPEEMSE
PLKRQWQALPELNPLFMPTGEGIEC
>Mature_265_residues
MLSLQQVTLESARYRWYGARRWSPLLQNVSFDIAPGEMVALVGGSGEGKSLLLQCLLDLLPENLRFRGEITLDGNRLDRH
TIRQLRGNTFSYVPQGVQALNPMLNIRKHLNRACHLTGRAWDETQMVQLLQQSDLEPTVLERFPRQLSGGMAKRILACHA
SLSQARYILADEITAWLDTALANQLLEHLRGLCERGCGVLWVTHDLLLAARYADRIVALHQGYITDNIRCEQLQPEEMSE
PLKRQWQALPELNPLFMPTGEGIEC

Specific function: Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system [H]

COG id: COG1123

COG function: function code R; ATPase components of various ABC-type transport systems, contain duplicated ATPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI90421313, Length=165, Percent_Identity=32.1212121212121, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1789890, Length=223, Percent_Identity=31.8385650224215, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI145693107, Length=225, Percent_Identity=29.7777777777778, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788506, Length=213, Percent_Identity=31.4553990610329, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789891, Length=219, Percent_Identity=30.5936073059361, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787105, Length=252, Percent_Identity=31.7460317460317, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787759, Length=218, Percent_Identity=30.2752293577982, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789672, Length=240, Percent_Identity=27.9166666666667, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI48994883, Length=210, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787089, Length=220, Percent_Identity=31.3636363636364, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1789963, Length=232, Percent_Identity=29.3103448275862, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787029, Length=219, Percent_Identity=28.310502283105, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788225, Length=232, Percent_Identity=29.7413793103448, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI48994997, Length=213, Percent_Identity=27.6995305164319, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790544, Length=228, Percent_Identity=30.7017543859649, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789991, Length=239, Percent_Identity=22.1757322175732, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788761, Length=210, Percent_Identity=30.4761904761905, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786872, Length=235, Percent_Identity=28.5106382978723, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787370, Length=197, Percent_Identity=29.9492385786802, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786703, Length=208, Percent_Identity=33.1730769230769, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787548, Length=249, Percent_Identity=24.4979919678715, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790467, Length=208, Percent_Identity=30.2884615384615, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787547, Length=243, Percent_Identity=24.2798353909465, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790739, Length=254, Percent_Identity=28.3464566929134, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI87081709, Length=203, Percent_Identity=27.5862068965517, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787758, Length=232, Percent_Identity=25.8620689655172, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789962, Length=250, Percent_Identity=25.2, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI48995001, Length=240, Percent_Identity=28.3333333333333, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788472, Length=203, Percent_Identity=25.615763546798, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787792, Length=218, Percent_Identity=27.9816513761468, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1789032, Length=206, Percent_Identity=26.2135922330097, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787500, Length=209, Percent_Identity=23.444976076555, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790190, Length=223, Percent_Identity=20.627802690583, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786345, Length=223, Percent_Identity=30.0448430493274, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71992285, Length=209, Percent_Identity=30.622009569378, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17552010, Length=199, Percent_Identity=29.6482412060301, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323959, Length=235, Percent_Identity=27.2340425531915, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17647219, Length=176, Percent_Identity=28.9772727272727, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45552805, Length=194, Percent_Identity=27.8350515463918, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015857
- InterPro:   IPR003593
- InterPro:   IPR014138 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.24 [H]

Molecular weight: Translated: 30078; Mature: 30078

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLQQVTLESARYRWYGARRWSPLLQNVSFDIAPGEMVALVGGSGEGKSLLLQCLLDLL
CCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHC
PENLRFRGEITLDGNRLDRHTIRQLRGNTFSYVPQGVQALNPMLNIRKHLNRACHLTGRA
CCCCEEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
WDETQMVQLLQQSDLEPTVLERFPRQLSGGMAKRILACHASLSQARYILADEITAWLDTA
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANQLLEHLRGLCERGCGVLWVTHDLLLAARYADRIVALHQGYITDNIRCEQLQPEEMSE
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHH
PLKRQWQALPELNPLFMPTGEGIEC
HHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLSLQQVTLESARYRWYGARRWSPLLQNVSFDIAPGEMVALVGGSGEGKSLLLQCLLDLL
CCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHC
PENLRFRGEITLDGNRLDRHTIRQLRGNTFSYVPQGVQALNPMLNIRKHLNRACHLTGRA
CCCCEEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
WDETQMVQLLQQSDLEPTVLERFPRQLSGGMAKRILACHASLSQARYILADEITAWLDTA
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANQLLEHLRGLCERGCGVLWVTHDLLLAARYADRIVALHQGYITDNIRCEQLQPEEMSE
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHH
PLKRQWQALPELNPLFMPTGEGIEC
HHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]