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The map label for this gene is sglT [H]

Identifier: 16764485

GI number: 16764485

Start: 1216441

End: 1217937

Strand: Reverse

Name: sglT [H]

Synonym: STM1128

Alternate gene names: 16764485

Gene position: 1217937-1216441 (Counterclockwise)

Preceding gene: 16764486

Following gene: 16764484

Centisome position: 25.07

GC content: 45.36

Gene sequence:

>1497_bases
ATGATTACACATTCTTTCGGCATCGTTAATTATCTTGTATTATTTGGCTACCTCCTGGCCATGATGTTAGTCGGTGTCTA
TTTTTCCAGACGGCAAAAAACAGCAGACGATTATTTTCGCGGTGGTGGCCGGGTTCCTGGTTGGGCGGCTGGGGTCAGTG
TATTTGCTACTACGTTAAGCTCAATTACATTTATGTCAATTCCTGCCAAAGCGTTTACTTCCGACTGGACGTTTATCATT
GGTCAGTATCTGGCTATCGCAATTTTACCGCTGGTTTTTTATTTCTATATTCCGTTTTTTCGGAAATTGAAAGTCACATC
AGCCTATGAATATCTCGAAGCACGGTTCGATGTGCGCTGCCGTCTGTTCGCCAGCATGTCATTTATGTTGTTTCATATTG
GACGTATCGCCATTATCACTTTCCTCACCGTGCTGGCCTTGCGCCCCTTCATCGCTATAGACCCGGTGATTTTGGTACTG
TTGATTAGCGTGATGTGTATCATTTATACCTGGATGGGTGGAATTGAAGGAGTAATATGGACTGATGTTATTCAAGGCCT
CTTACTTTCTGGCAGCGCGATACTGATTTTTATAGTGATATGTCTCAAAGTCCAGGGCGGCATTGATGAAATTTTTACGG
TGACGCAGCAGGCGGATAAATTCTTTCCGGCTACGCAGTTCCACTGGAGCTGGACGGAAAGCACAGTACCTGTATTGATG
ATTGGTTTTCTGTTTGCCAATATTCAGCAATTTACTGCCAGTCAGGATGTGGTCCAACGCTATATCGTGACTGACTCCAT
AGAGGAAACGAAGAAAACATTACTTACAAATGCCAAACTGGTTGCTGTGATCCCTGTTTTCTTTTTTGCTATCGGCTCGG
CATTGTTTGTCTATTATCAGCAACATCCACAATTATTACCGGCGGGATTCAACACTGGCGGCATTTTGCCCTTATTCGTG
GTCACCGAAATGCCAGTCGGCATTGCAGGGTTGATAATCGCCGCTATTTTCGCTGCTGCGCAGTCCAGTATCTCCAGCAG
CTTAAACAGCATTTCCAGTTGTTTTAATTCCGATATCTATCAGCGTTTGAGTCATAAAAAAAGAACGCCAGAAAACCGTA
TGAAAATAGCTAAGTTAGTTATTCTGGTCGCGGGCTTGATAAGTAGCGCGGCCTCGGTATGGCTGGTCATGGCCGATGAA
TCAGAAATCTGGGATGCATTTAATAGTCTGATAGGTCTGATGGGAGGGCCAATGACCGGTCTGTTCATGCTGGGCATTTT
CTTTAAACGAGCAAATGCCGGGAGTGCGGTTTTAGGAATTATTATCAGCGTCATTACCGTGCTGGGCGCACGCTATGCCA
CTGACCTTAACTTCTTCTTTTATGGGGTCATTGGCTCGCTAAGCGTGGTGATCAGCGGCGTTATTTTCGCCCCGTTATTT
GCCCCGGCACCGCCATTGACGCTGGATGAAAAACCTGAACCAAAGGTGACATTATGA

Upstream 100 bases:

>100_bases
TATTACTTGATCTGAATATCGTATCGTCTGAATGATGGGAAGATAAAAATACACAGACGATGACCGCAACTCTACTCAAA
ACCATAAGCAGGAAAGAACT

Downstream 100 bases:

>100_bases
TTTCATGATACCACGCTATACCGACACAGCATACGGTGACGCCAACGCGCGGGGCGACAATACCGGGCCAGGTATAAACC
ATCCGTCAAATGGCGCGCTA

Product: sodium/glucose cotransporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MITHSFGIVNYLVLFGYLLAMMLVGVYFSRRQKTADDYFRGGGRVPGWAAGVSVFATTLSSITFMSIPAKAFTSDWTFII
GQYLAIAILPLVFYFYIPFFRKLKVTSAYEYLEARFDVRCRLFASMSFMLFHIGRIAIITFLTVLALRPFIAIDPVILVL
LISVMCIIYTWMGGIEGVIWTDVIQGLLLSGSAILIFIVICLKVQGGIDEIFTVTQQADKFFPATQFHWSWTESTVPVLM
IGFLFANIQQFTASQDVVQRYIVTDSIEETKKTLLTNAKLVAVIPVFFFAIGSALFVYYQQHPQLLPAGFNTGGILPLFV
VTEMPVGIAGLIIAAIFAAAQSSISSSLNSISSCFNSDIYQRLSHKKRTPENRMKIAKLVILVAGLISSAASVWLVMADE
SEIWDAFNSLIGLMGGPMTGLFMLGIFFKRANAGSAVLGIIISVITVLGARYATDLNFFFYGVIGSLSVVISGVIFAPLF
APAPPLTLDEKPEPKVTL

Sequences:

>Translated_498_residues
MITHSFGIVNYLVLFGYLLAMMLVGVYFSRRQKTADDYFRGGGRVPGWAAGVSVFATTLSSITFMSIPAKAFTSDWTFII
GQYLAIAILPLVFYFYIPFFRKLKVTSAYEYLEARFDVRCRLFASMSFMLFHIGRIAIITFLTVLALRPFIAIDPVILVL
LISVMCIIYTWMGGIEGVIWTDVIQGLLLSGSAILIFIVICLKVQGGIDEIFTVTQQADKFFPATQFHWSWTESTVPVLM
IGFLFANIQQFTASQDVVQRYIVTDSIEETKKTLLTNAKLVAVIPVFFFAIGSALFVYYQQHPQLLPAGFNTGGILPLFV
VTEMPVGIAGLIIAAIFAAAQSSISSSLNSISSCFNSDIYQRLSHKKRTPENRMKIAKLVILVAGLISSAASVWLVMADE
SEIWDAFNSLIGLMGGPMTGLFMLGIFFKRANAGSAVLGIIISVITVLGARYATDLNFFFYGVIGSLSVVISGVIFAPLF
APAPPLTLDEKPEPKVTL
>Mature_498_residues
MITHSFGIVNYLVLFGYLLAMMLVGVYFSRRQKTADDYFRGGGRVPGWAAGVSVFATTLSSITFMSIPAKAFTSDWTFII
GQYLAIAILPLVFYFYIPFFRKLKVTSAYEYLEARFDVRCRLFASMSFMLFHIGRIAIITFLTVLALRPFIAIDPVILVL
LISVMCIIYTWMGGIEGVIWTDVIQGLLLSGSAILIFIVICLKVQGGIDEIFTVTQQADKFFPATQFHWSWTESTVPVLM
IGFLFANIQQFTASQDVVQRYIVTDSIEETKKTLLTNAKLVAVIPVFFFAIGSALFVYYQQHPQLLPAGFNTGGILPLFV
VTEMPVGIAGLIIAAIFAAAQSSISSSLNSISSCFNSDIYQRLSHKKRTPENRMKIAKLVILVAGLISSAASVWLVMADE
SEIWDAFNSLIGLMGGPMTGLFMLGIFFKRANAGSAVLGIIISVITVLGARYATDLNFFFYGVIGSLSVVISGVIFAPLF
APAPPLTLDEKPEPKVTL

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI256985183, Length=463, Percent_Identity=27.2138228941685, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI167466278, Length=512, Percent_Identity=27.5390625, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI4507035, Length=452, Percent_Identity=26.9911504424779, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI157671931, Length=470, Percent_Identity=23.8297872340426, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI4507031, Length=454, Percent_Identity=25.5506607929515, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI14140236, Length=465, Percent_Identity=22.7956989247312, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI206597483, Length=447, Percent_Identity=23.9373601789709, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI109659839, Length=486, Percent_Identity=22.6337448559671, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI110835708, Length=462, Percent_Identity=23.5930735930736, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI109659836, Length=470, Percent_Identity=23.1914893617021, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4507033, Length=471, Percent_Identity=22.9299363057325, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI17941285, Length=454, Percent_Identity=22.6872246696035, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI206597487, Length=375, Percent_Identity=24.5333333333333, Blast_Score=83, Evalue=8e-16,
Organism=Escherichia coli, GI1790113, Length=463, Percent_Identity=21.5982721382289, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787251, Length=389, Percent_Identity=21.8508997429306, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI32566512, Length=372, Percent_Identity=28.494623655914, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI115533094, Length=422, Percent_Identity=23.696682464455, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI115533096, Length=314, Percent_Identity=22.2929936305732, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24651739, Length=467, Percent_Identity=28.6937901498929, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI221459588, Length=479, Percent_Identity=26.9311064718163, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI221459584, Length=479, Percent_Identity=28.1837160751566, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24645928, Length=466, Percent_Identity=26.8240343347639, Blast_Score=148, Evalue=9e-36,
Organism=Drosophila melanogaster, GI28573698, Length=450, Percent_Identity=25.1111111111111, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24651741, Length=435, Percent_Identity=25.7471264367816, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI221459586, Length=483, Percent_Identity=25.4658385093168, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI281362918, Length=468, Percent_Identity=27.5641025641026, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24640370, Length=469, Percent_Identity=25.5863539445629, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24641117, Length=451, Percent_Identity=27.0509977827051, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI221459582, Length=480, Percent_Identity=26.875, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28574994, Length=460, Percent_Identity=26.5217391304348, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI161076631, Length=486, Percent_Identity=26.3374485596708, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI221379702, Length=468, Percent_Identity=26.0683760683761, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281362054, Length=445, Percent_Identity=24.9438202247191, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI281362052, Length=445, Percent_Identity=24.9438202247191, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI281362050, Length=445, Percent_Identity=24.9438202247191, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24648056, Length=445, Percent_Identity=24.9438202247191, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI21356827, Length=445, Percent_Identity=24.9438202247191, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24650192, Length=482, Percent_Identity=22.6141078838174, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281364280, Length=484, Percent_Identity=26.0330578512397, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI19920916, Length=479, Percent_Identity=27.9749478079332, Blast_Score=112, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 54778; Mature: 54778

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure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CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]