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The map label for this gene is hpaX [H]

Identifier: 16764465

GI number: 16764465

Start: 1194036

End: 1195412

Strand: Direct

Name: hpaX [H]

Synonym: STM1107

Alternate gene names: 16764465

Gene position: 1194036-1195412 (Clockwise)

Preceding gene: 16764464

Following gene: 16764466

Centisome position: 24.58

GC content: 53.09

Gene sequence:

>1377_bases
ATGAGCGACACATCATCTGCACTTCCGGAAAGCCCCGAGTCTGTCAGTTCGCACAACGCGCTCAGCACGGGTCAACAAAC
CGTCATAAATAAACTGTTCCGCCGACTGATCGTATTTTTATTCGTGTTGTTTATCTTCTCGTTTTTAGACCGTATCAACA
TCGGTTTTGCCGGGTTGACGATGGGGCAGGATCTGGGGTTAAGCGCCACCATGTTTGGTCTTGCCACGACGCTGTTTTAC
GCTACCTACGTCATTTTCGGCATTCCCAGCAACGTGATGTTGAGCATCGTCGGCGCCCGCCACTGGATTGCGACCATTAT
GGTGCTATGGGGCATTGCATCTACCGCCACGATGTTCGCGGTGGGACCGAAAAGCCTGTATGTGCTGCGAATGCTGGTGG
GCATTACCGAAGCGGGCTTTTTGCCAGGAATATTGCTCTATTTAACCTACTGGTTCCCGGCATTTTTCCGCGCCCGCGCC
AACGCATTATTTATGATTGCCATGCCGGCCACTACCGCGTTGGGGTCGATTGTCTCCGGCTATATTTTATCGCTGGACGG
CATATTCAATCTGCATGGATGGCAGTGGTTATTCCTGTTGGAAGGATTTCCGTCAGTTTTGTTAGGCATTATGGTCTGGT
TTTACCTGGATGATACCCCGGCAAAAGCCAAATGGCTGACGGCAGAGGATAAAAAATGTTTGCAGGAGATGATGGATAGT
GACCGCCTGACGCTGGTTCAGCCGGAGGGGGCCATCAGCCATAACGCCATGCAGCAGCGTAGTCTGTGGCGCGAAGTATT
CACGCCAATTGTACTGATGTATACGCTGGCCTATTTTTGCCTTACCAATACGCTTAGCGCCATTAGTATCTGGACGCCGC
AAATCCTGAAAAGTTTTAATGAAGGCAGCAGCAATATCACCATCGGCCTGCTGGCGGCGATCCCGCAGATTTGTACTATT
CTGGGCATGATTTACTGGAGCCGCCATTCGGACAAACATCAGGAGCGTAAACATCACACGGCGTTGCCGTTCCTGTTTGC
CGCCGCGGGCTGGCTGCTGGCGTCGGCGACCGACCATAACCTGATCCAGCTCCTGGGGATCGTGATGGCATCCACGGGTT
CCTTTAGCGCGATGGCGATCTTCTGGACCACGCCGGATCAGTCGATCAGTTTACGCGCCAGGGCGATAGGCATTGCGGTC
ATCAATGCCACCGGCAATATTGGCTCCGCGCTCAGCCCGTTTATGATTGGCTGGCTAAAAGATATCACCGGTAGCTTCAA
TAGCGGACTCTGGTTTGTCGCTTCTCTGTTAGTCGTCGGCGCCGCCATTATCTGGCTTATTCCCATGAAAGCATCGCGTC
CGCGCGCCACCCCTTGA

Upstream 100 bases:

>100_bases
AACTGTCCGGTGCGTCCGGCGTCTATTAAGCCTGGCCCCGTAAGCGCAGCGCTACCGGGCAACCGTAGTACCCTACAAAA
TTCCCATCAGAGGAAAAAAA

Downstream 100 bases:

>100_bases
GGAGAAACTATGTGCCAACGTGCGATCGCCAATATTGATATCAGCAAAGAGTATGACGAAAGCATGGGCAGTAACGATGT
GCATTATCAGTCGTTTGCTC

Product: 4-hydroxyphenylacetate catabolism

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MSDTSSALPESPESVSSHNALSTGQQTVINKLFRRLIVFLFVLFIFSFLDRINIGFAGLTMGQDLGLSATMFGLATTLFY
ATYVIFGIPSNVMLSIVGARHWIATIMVLWGIASTATMFAVGPKSLYVLRMLVGITEAGFLPGILLYLTYWFPAFFRARA
NALFMIAMPATTALGSIVSGYILSLDGIFNLHGWQWLFLLEGFPSVLLGIMVWFYLDDTPAKAKWLTAEDKKCLQEMMDS
DRLTLVQPEGAISHNAMQQRSLWREVFTPIVLMYTLAYFCLTNTLSAISIWTPQILKSFNEGSSNITIGLLAAIPQICTI
LGMIYWSRHSDKHQERKHHTALPFLFAAAGWLLASATDHNLIQLLGIVMASTGSFSAMAIFWTTPDQSISLRARAIGIAV
INATGNIGSALSPFMIGWLKDITGSFNSGLWFVASLLVVGAAIIWLIPMKASRPRATP

Sequences:

>Translated_458_residues
MSDTSSALPESPESVSSHNALSTGQQTVINKLFRRLIVFLFVLFIFSFLDRINIGFAGLTMGQDLGLSATMFGLATTLFY
ATYVIFGIPSNVMLSIVGARHWIATIMVLWGIASTATMFAVGPKSLYVLRMLVGITEAGFLPGILLYLTYWFPAFFRARA
NALFMIAMPATTALGSIVSGYILSLDGIFNLHGWQWLFLLEGFPSVLLGIMVWFYLDDTPAKAKWLTAEDKKCLQEMMDS
DRLTLVQPEGAISHNAMQQRSLWREVFTPIVLMYTLAYFCLTNTLSAISIWTPQILKSFNEGSSNITIGLLAAIPQICTI
LGMIYWSRHSDKHQERKHHTALPFLFAAAGWLLASATDHNLIQLLGIVMASTGSFSAMAIFWTTPDQSISLRARAIGIAV
INATGNIGSALSPFMIGWLKDITGSFNSGLWFVASLLVVGAAIIWLIPMKASRPRATP
>Mature_457_residues
SDTSSALPESPESVSSHNALSTGQQTVINKLFRRLIVFLFVLFIFSFLDRINIGFAGLTMGQDLGLSATMFGLATTLFYA
TYVIFGIPSNVMLSIVGARHWIATIMVLWGIASTATMFAVGPKSLYVLRMLVGITEAGFLPGILLYLTYWFPAFFRARAN
ALFMIAMPATTALGSIVSGYILSLDGIFNLHGWQWLFLLEGFPSVLLGIMVWFYLDDTPAKAKWLTAEDKKCLQEMMDSD
RLTLVQPEGAISHNAMQQRSLWREVFTPIVLMYTLAYFCLTNTLSAISIWTPQILKSFNEGSSNITIGLLAAIPQICTIL
GMIYWSRHSDKHQERKHHTALPFLFAAAGWLLASATDHNLIQLLGIVMASTGSFSAMAIFWTTPDQSISLRARAIGIAVI
NATGNIGSALSPFMIGWLKDITGSFNSGLWFVASLLVVGAAIIWLIPMKASRPRATP

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=420, Percent_Identity=30.4761904761905, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1789515, Length=424, Percent_Identity=24.2924528301887, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI87082320, Length=434, Percent_Identity=21.6589861751152, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789152, Length=453, Percent_Identity=22.5165562913907, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI2367379, Length=463, Percent_Identity=22.6781857451404, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322025, Length=436, Percent_Identity=25.9174311926606, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321698, Length=213, Percent_Identity=25.3521126760563, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324410, Length=168, Percent_Identity=25, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50353; Mature: 50222

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTSSALPESPESVSSHNALSTGQQTVINKLFRRLIVFLFVLFIFSFLDRINIGFAGLT
CCCCCCCCCCCCCHHHCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
MGQDLGLSATMFGLATTLFYATYVIFGIPSNVMLSIVGARHWIATIMVLWGIASTATMFA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
VGPKSLYVLRMLVGITEAGFLPGILLYLTYWFPAFFRARANALFMIAMPATTALGSIVSG
ECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHH
YILSLDGIFNLHGWQWLFLLEGFPSVLLGIMVWFYLDDTPAKAKWLTAEDKKCLQEMMDS
HHHHCCCEEECCCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHCC
DRLTLVQPEGAISHNAMQQRSLWREVFTPIVLMYTLAYFCLTNTLSAISIWTPQILKSFN
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
EGSSNITIGLLAAIPQICTILGMIYWSRHSDKHQERKHHTALPFLFAAAGWLLASATDHN
CCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LIQLLGIVMASTGSFSAMAIFWTTPDQSISLRARAIGIAVINATGNIGSALSPFMIGWLK
HHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHHH
DITGSFNSGLWFVASLLVVGAAIIWLIPMKASRPRATP
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SDTSSALPESPESVSSHNALSTGQQTVINKLFRRLIVFLFVLFIFSFLDRINIGFAGLT
CCCCCCCCCCCCHHHCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
MGQDLGLSATMFGLATTLFYATYVIFGIPSNVMLSIVGARHWIATIMVLWGIASTATMFA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
VGPKSLYVLRMLVGITEAGFLPGILLYLTYWFPAFFRARANALFMIAMPATTALGSIVSG
ECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHH
YILSLDGIFNLHGWQWLFLLEGFPSVLLGIMVWFYLDDTPAKAKWLTAEDKKCLQEMMDS
HHHHCCCEEECCCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHCC
DRLTLVQPEGAISHNAMQQRSLWREVFTPIVLMYTLAYFCLTNTLSAISIWTPQILKSFN
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
EGSSNITIGLLAAIPQICTILGMIYWSRHSDKHQERKHHTALPFLFAAAGWLLASATDHN
CCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LIQLLGIVMASTGSFSAMAIFWTTPDQSISLRARAIGIAVINATGNIGSALSPFMIGWLK
HHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHHH
DITGSFNSGLWFVASLLVVGAAIIWLIPMKASRPRATP
HHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]