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The map label for this gene is hpaH [H]

Identifier: 16764463

GI number: 16764463

Start: 1192359

End: 1193162

Strand: Direct

Name: hpaH [H]

Synonym: STM1105

Alternate gene names: 16764463

Gene position: 1192359-1193162 (Clockwise)

Preceding gene: 16764462

Following gene: 16764464

Centisome position: 24.55

GC content: 59.08

Gene sequence:

>804_bases
ATGCTCGATAAACAGACCCATACCCTGATCGCCCAGCGACTTAATCAGGCTGAAAAACAGCGCGAACAGATTCGCGCAGT
GTCGCTGGATTATCCCAACATCACTATTGAAGATGCCTATGCCGTACAGCGTGAATGGGTCAATATCAAGATTGCCGAAG
GGCGCACGCTCAAAGGCCACAAAATCGGCCTGACCTCAAAAGCGATGCAGGCCAGCTCGCAAATCAGCGAACCGGATTAC
GGCGCGCTGCTTGACGATATGTTCTTCCATGACGGCGGCGATATCCCCACCGACCGTTTTATCGTCCCGCGTATTGAAGT
GGAGCTGGCGTTCGTGCTGGCGAAACCGCTGCGCGGCCCTCACTGCACGCTGTTCGACGTCTACAACGCCACGGATTATG
TGATTCCGGCGCTGGAACTGATTGACGCCCGCAGCCACAACATCGACCCGGAAACCCAGCGTCCGCGCAAAGTGTTCGAC
ACCATTTCCGACAACGCCGCCAACGCCGGGGTGATCCTCGGTGGTCGTCCCATCAAACCAGACGAGCTGGATCTGCGCTG
GATCTCCGCGCTGCTCTATCGCAACGGCGTGATCGAAGAAACCGGCGTCGCCGCAGGCGTGCTGAATCATCCGGCCAACG
GCGTGGCGTGGCTGGCGAACAAGCTTGCCCCCTACGATGTCCAGCTTGAAGCCGGGCAGATCATCCTCGGCGGCTCGTTC
ACCCGCCCGGTGCCGGCGCGCAAGGGCGACACCTTCCATGTCGATTACGGCAACATGGGCGCGATCAGTTGCCGGTTTGT
GTAA

Upstream 100 bases:

>100_bases
AAAAAACGATGCACGAAGCAATACCGAACCGTAGGCCGGGTAAGACGCACCCGCGTCGCCACCCGGCACAGCAGCACCGA
ATGACGTAACAGGAAACACT

Downstream 100 bases:

>100_bases
GGAAAAAACGATGAAAAATGCTTTCAAAGACGCGTTAAAAGCGGGGCGTCCGCAAATCGGTTTGTGGCTGGGGCTTGCCA
ACAGTTACAGCGCTGAACTG

Product: 4-hydroxyphenylacetate catabolism

Products: NA

Alternate protein names: OHED hydratase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MLDKQTHTLIAQRLNQAEKQREQIRAVSLDYPNITIEDAYAVQREWVNIKIAEGRTLKGHKIGLTSKAMQASSQISEPDY
GALLDDMFFHDGGDIPTDRFIVPRIEVELAFVLAKPLRGPHCTLFDVYNATDYVIPALELIDARSHNIDPETQRPRKVFD
TISDNAANAGVILGGRPIKPDELDLRWISALLYRNGVIEETGVAAGVLNHPANGVAWLANKLAPYDVQLEAGQIILGGSF
TRPVPARKGDTFHVDYGNMGAISCRFV

Sequences:

>Translated_267_residues
MLDKQTHTLIAQRLNQAEKQREQIRAVSLDYPNITIEDAYAVQREWVNIKIAEGRTLKGHKIGLTSKAMQASSQISEPDY
GALLDDMFFHDGGDIPTDRFIVPRIEVELAFVLAKPLRGPHCTLFDVYNATDYVIPALELIDARSHNIDPETQRPRKVFD
TISDNAANAGVILGGRPIKPDELDLRWISALLYRNGVIEETGVAAGVLNHPANGVAWLANKLAPYDVQLEAGQIILGGSF
TRPVPARKGDTFHVDYGNMGAISCRFV
>Mature_267_residues
MLDKQTHTLIAQRLNQAEKQREQIRAVSLDYPNITIEDAYAVQREWVNIKIAEGRTLKGHKIGLTSKAMQASSQISEPDY
GALLDDMFFHDGGDIPTDRFIVPRIEVELAFVLAKPLRGPHCTLFDVYNATDYVIPALELIDARSHNIDPETQRPRKVFD
TISDNAANAGVILGGRPIKPDELDLRWISALLYRNGVIEETGVAAGVLNHPANGVAWLANKLAPYDVQLEAGQIILGGSF
TRPVPARKGDTFHVDYGNMGAISCRFV

Specific function: Transforms 2-oxo-hept-3-ene-1,7-dioate (OHED) into 2,4- dihydoxy-hept-2-ene-1,7-dioic acid (HHED) [H]

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hydratase/decarboxylase family [H]

Homologues:

Organism=Escherichia coli, GI87081722, Length=266, Percent_Identity=33.4586466165414, Blast_Score=141, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234
- InterPro:   IPR012690 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: 4.2.1.-

Molecular weight: Translated: 29543; Mature: 29543

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKQTHTLIAQRLNQAEKQREQIRAVSLDYPNITIEDAYAVQREWVNIKIAEGRTLKGH
CCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEECCHHHEEEEEEEEEEECCCEECCC
KIGLTSKAMQASSQISEPDYGALLDDMFFHDGGDIPTDRFIVPRIEVELAFVLAKPLRGP
EECCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCEEECEEHEEEEEEECCCCCCC
HCTLFDVYNATDYVIPALELIDARSHNIDPETQRPRKVFDTISDNAANAGVILGGRPIKP
CEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEECCCCCCC
DELDLRWISALLYRNGVIEETGVAAGVLNHPANGVAWLANKLAPYDVQLEAGQIILGGSF
CCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHCCCCCEEEEECCEEEECCCC
TRPVPARKGDTFHVDYGNMGAISCRFV
CCCCCCCCCCEEEEECCCCCEEEEEEC
>Mature Secondary Structure
MLDKQTHTLIAQRLNQAEKQREQIRAVSLDYPNITIEDAYAVQREWVNIKIAEGRTLKGH
CCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEECCHHHEEEEEEEEEEECCCEECCC
KIGLTSKAMQASSQISEPDYGALLDDMFFHDGGDIPTDRFIVPRIEVELAFVLAKPLRGP
EECCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCEEECEEHEEEEEEECCCCCCC
HCTLFDVYNATDYVIPALELIDARSHNIDPETQRPRKVFDTISDNAANAGVILGGRPIKP
CEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEECCCCCCC
DELDLRWISALLYRNGVIEETGVAAGVLNHPANGVAWLANKLAPYDVQLEAGQIILGGSF
CCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHCCCCCEEEEECCEEEECCCC
TRPVPARKGDTFHVDYGNMGAISCRFV
CCCCCCCCCCEEEEECCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7737515 [H]