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The map label for this gene is sseI

Identifier: 16764411

GI number: 16764411

Start: 1139971

End: 1140939

Strand: Direct

Name: sseI

Synonym: STM1051

Alternate gene names: 16764411

Gene position: 1139971-1140939 (Clockwise)

Preceding gene: 16764410

Following gene: 16764416

Centisome position: 23.47

GC content: 41.07

Gene sequence:

>969_bases
ATGCCCTTTCATATTGGAAGCGGATGTCTTCCCGCCATCATCAGTAACCGCCGCATTTATCGTATTGCCTGGTCTGATAC
CCCCCCTGAAATGAGTTCCTGGGAAAAAATGAAGGAATTTTTTTGCTCAACGCACCAGGCTGAAGCGCTGGAGTGCATCT
GGACGATTTGTCACCCGCCGGCCGGAACGACGCGGGAGGATGTGGTCAGCAGATTTGAACTGCTCAGGACGCTCGCGTAT
GACGGATGGGAGGAAAACATTCATTCCGGCCTGCACGGGGAAAACTACTTCTGTATTCTGGATGAAGACAGTCAGGAGAT
ATTATCAGTCACCCTGGATGACGTCGGGAACTATACCGTAAATTGCCAGGGGTACAGTGAAACACATCACTTAACCATGG
CAACAGAACCGGGAGTGGAACGCACAGATATAACTTACAACCTAACCAGTGATATTGATGCTGCGGCCTATCTGGAGGAA
TTGAAACAGAATCCAATTATAAATAATAAAATAATGAATCCGGTAGGGCAGTGTGAGTCATTAATGACTCCTGTAAGCAA
TTTTATGAATGAAAAAGGGTTCGATAATATTCGTTATCGAGGTATATTTATCTGGGATAAACCAACAGAGGAAATACCAA
CAAATCATTTTGCAGTGGTTGGAAATAAAGAAGGAAAAGACTATGTGTTTGATGTTTCAGCCCATCAGTTTGAAAATAGA
GGTATGAGTAATCTGAATGGCCCATTAATTCTTTCAGCAGATGAATGGGTTTGTAAATATAGAATGGCAACAAGAAGGAA
ACTTATTTATTATACTGATTTTAGTAATTCAAGTATAGCAGCTAATGCCTATGATGCATTACCACGAGAATTAGAATCAG
AATCTATGGCAGGGAAAGTTTTTGTTACATCACCGAGATGGTTTAATACCTTTAAAAAGCAAAAATATTCCTTAATAGGT
AAAATGTAA

Upstream 100 bases:

>100_bases
GACCATGAATCCGCCGATAACCTTATTGTGAAATTAAGGCCAGGAAGAGATGATGTCTGTCGGACAGATACTATATGTAA
ATTTATAAAGGTTTTTTGTT

Downstream 100 bases:

>100_bases
GCGCACCGTGGAGGACGTCTGTCAGAACCCTGTCAATCCGGCGATGATAGTGTCCACTTAAATTTTGATGGACACTATCA
CAGATGACAGAGTCCACAGC

Product: secreted effector protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MPFHIGSGCLPAIISNRRIYRIAWSDTPPEMSSWEKMKEFFCSTHQAEALECIWTICHPPAGTTREDVVSRFELLRTLAY
DGWEENIHSGLHGENYFCILDEDSQEILSVTLDDVGNYTVNCQGYSETHHLTMATEPGVERTDITYNLTSDIDAAAYLEE
LKQNPIINNKIMNPVGQCESLMTPVSNFMNEKGFDNIRYRGIFIWDKPTEEIPTNHFAVVGNKEGKDYVFDVSAHQFENR
GMSNLNGPLILSADEWVCKYRMATRRKLIYYTDFSNSSIAANAYDALPRELESESMAGKVFVTSPRWFNTFKKQKYSLIG
KM

Sequences:

>Translated_322_residues
MPFHIGSGCLPAIISNRRIYRIAWSDTPPEMSSWEKMKEFFCSTHQAEALECIWTICHPPAGTTREDVVSRFELLRTLAY
DGWEENIHSGLHGENYFCILDEDSQEILSVTLDDVGNYTVNCQGYSETHHLTMATEPGVERTDITYNLTSDIDAAAYLEE
LKQNPIINNKIMNPVGQCESLMTPVSNFMNEKGFDNIRYRGIFIWDKPTEEIPTNHFAVVGNKEGKDYVFDVSAHQFENR
GMSNLNGPLILSADEWVCKYRMATRRKLIYYTDFSNSSIAANAYDALPRELESESMAGKVFVTSPRWFNTFKKQKYSLIG
KM
>Mature_321_residues
PFHIGSGCLPAIISNRRIYRIAWSDTPPEMSSWEKMKEFFCSTHQAEALECIWTICHPPAGTTREDVVSRFELLRTLAYD
GWEENIHSGLHGENYFCILDEDSQEILSVTLDDVGNYTVNCQGYSETHHLTMATEPGVERTDITYNLTSDIDAAAYLEEL
KQNPIINNKIMNPVGQCESLMTPVSNFMNEKGFDNIRYRGIFIWDKPTEEIPTNHFAVVGNKEGKDYVFDVSAHQFENRG
MSNLNGPLILSADEWVCKYRMATRRKLIYYTDFSNSSIAANAYDALPRELESESMAGKVFVTSPRWFNTFKKQKYSLIGK
M

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is required to maintain a long-term chronic systemic infection in mice. It inhibits normal cell migration of primary macrophages and dend

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cytoplasm. Note=Secreted via type III secretion system 2 (SPI-2 TTSS), and delivered into the host cytoplasm. Colocalizes with IQGAP1 and actin at the cell periphery

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SSEI_SALTY (Q8ZQ79)

Other databases:

- EMBL:   AF231470
- EMBL:   AF236075
- EMBL:   AE006468
- RefSeq:   NP_460026.1
- GeneID:   1252569
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM1051
- NMPDR:   fig|99287.1.peg.1019
- HOGENOM:   HBG673361
- OMA:   ILSADEW
- ProtClustDB:   PRK15372
- BioCyc:   STYP99287:STM1051-MONOMER
- GO:   GO:0009405

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 36831; Mature: 36700

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFHIGSGCLPAIISNRRIYRIAWSDTPPEMSSWEKMKEFFCSTHQAEALECIWTICHPP
CCCCCCCCCHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
AGTTREDVVSRFELLRTLAYDGWEENIHSGLHGENYFCILDEDSQEILSVTLDDVGNYTV
CCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEEECCCCHHHHHEECCCCCCEEE
NCQGYSETHHLTMATEPGVERTDITYNLTSDIDAAAYLEELKQNPIINNKIMNPVGQCES
EEECCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCHHHCCHHHHHHH
LMTPVSNFMNEKGFDNIRYRGIFIWDKPTEEIPTNHFAVVGNKEGKDYVFDVSAHQFENR
HHHHHHHHHHCCCCCCEEEEEEEEECCCHHHCCCCCEEEEECCCCCCEEEECHHHHHHHC
GMSNLNGPLILSADEWVCKYRMATRRKLIYYTDFSNSSIAANAYDALPRELESESMAGKV
CCCCCCCCEEEECCHHHHHHHHHHCCEEEEEEECCCCCEECCHHHHHHHHHCCCCCCCEE
FVTSPRWFNTFKKQKYSLIGKM
EEECCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PFHIGSGCLPAIISNRRIYRIAWSDTPPEMSSWEKMKEFFCSTHQAEALECIWTICHPP
CCCCCCCCHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
AGTTREDVVSRFELLRTLAYDGWEENIHSGLHGENYFCILDEDSQEILSVTLDDVGNYTV
CCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEEECCCCHHHHHEECCCCCCEEE
NCQGYSETHHLTMATEPGVERTDITYNLTSDIDAAAYLEELKQNPIINNKIMNPVGQCES
EEECCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCHHHCCHHHHHHH
LMTPVSNFMNEKGFDNIRYRGIFIWDKPTEEIPTNHFAVVGNKEGKDYVFDVSAHQFENR
HHHHHHHHHHCCCCCCEEEEEEEEECCCHHHCCCCCEEEEECCCCCCEEEECHHHHHHHC
GMSNLNGPLILSADEWVCKYRMATRRKLIYYTDFSNSSIAANAYDALPRELESESMAGKV
CCCCCCCCEEEECCHHHHHHHHHHCCEEEEEEECCCCCEECCHHHHHHHHHCCCCCCCEE
FVTSPRWFNTFKKQKYSLIGKM
EEECCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10844662; 10861017; 11677609