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The map label for this gene is panC [H]

Identifier: 16763571

GI number: 16763571

Start: 211506

End: 212360

Strand: Reverse

Name: panC [H]

Synonym: STM0181

Alternate gene names: 16763571

Gene position: 212360-211506 (Counterclockwise)

Preceding gene: 16763572

Following gene: 16763570

Centisome position: 4.37

GC content: 54.5

Gene sequence:

>855_bases
GTGCTAATCATTGAAACCCTGCCGCTGCTGCGCCAGCATATTCGTCGTCTGCGTCAGGAAGGTAAACGCGTCGCACTGGT
TCCCACCATGGGCAACCTGCACGACGGCCATATGAAGCTGGTCGATGAGGCAAAAGCCCGGGCTGATGTGGTGATCGTCA
GCATTTTCGTCAATCCGATGCAGTTTGATCGGCCGGACGATCTGGTGCGTTATCCGCGCACGCTGCAGGAAGATTGTGAA
AAGCTGAACAAACGCAAAGTCGATTATGTCTTTGCGCCAGCCGTTGAGGAAATCTACCCGCATGGGCTGGAAGGCCAGAC
GTACGTTGATGTTCCCGGCCTCTCTACCATGCTGGAAGGCGCCAGCCGTCCAGGTCATTTCCGCGGCGTCTCGACTATCG
TCAGCAAGCTGTTCAACCTGATCCAGCCGGATATCGCCTGCTTTGGCGAGAAGGATTTCCAGCAACTGGCGCTGATCCGC
AAAATGGTGGCGGATATGAGTTATGACATTGAGATCGTCGGCGTGCCGATTATTCGCGCTAAAGACGGTCTGGCGCTCAG
CTCACGTAACGCTTATCTGACCGCAGAGCAGCGCAAAATTGCGCCGGGTCTATACAACGTGATGAATAGCATCGCTGAAA
AACTGATTGCGGGTAATCGTGAGCTGCAAGAGATTATTGCCATTGCCGAACAGGAACTGAATGAAAAAGGCTTCCGTGCC
GACGACATTCAAATCCGTGATGCCGACACGCTGCTGGAGCTGACGGAAACCAGCAAACGCGCAGTGATTCTGGCTGCCGC
CTGGCTGGGTCAGGCGCGTCTGATCGATAATCAAAGCGTTACATTAGCCCAGTAG

Upstream 100 bases:

>100_bases
CGCGACGCGTCTTATCCGGCCTACAGATCCTCAACGGATGTAGGCCTGATAAGCGCAGCGCCATCGGGCAGGATCATCAA
GCAACTCAAGGAGTTTTGTT

Downstream 100 bases:

>100_bases
ACAGGGGTTAAAAATCGGGCAATACTGCCTGAGAATTTCCAAAGCAGGCCACAAGCGCCTGCTTAGCCAAGGTAAACGAC
AGGGTAAAGAAGTTATGATT

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MLIIETLPLLRQHIRRLRQEGKRVALVPTMGNLHDGHMKLVDEAKARADVVIVSIFVNPMQFDRPDDLVRYPRTLQEDCE
KLNKRKVDYVFAPAVEEIYPHGLEGQTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLIQPDIACFGEKDFQQLALIR
KMVADMSYDIEIVGVPIIRAKDGLALSSRNAYLTAEQRKIAPGLYNVMNSIAEKLIAGNRELQEIIAIAEQELNEKGFRA
DDIQIRDADTLLELTETSKRAVILAAAWLGQARLIDNQSVTLAQ

Sequences:

>Translated_284_residues
MLIIETLPLLRQHIRRLRQEGKRVALVPTMGNLHDGHMKLVDEAKARADVVIVSIFVNPMQFDRPDDLVRYPRTLQEDCE
KLNKRKVDYVFAPAVEEIYPHGLEGQTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLIQPDIACFGEKDFQQLALIR
KMVADMSYDIEIVGVPIIRAKDGLALSSRNAYLTAEQRKIAPGLYNVMNSIAEKLIAGNRELQEIIAIAEQELNEKGFRA
DDIQIRDADTLLELTETSKRAVILAAAWLGQARLIDNQSVTLAQ
>Mature_284_residues
MLIIETLPLLRQHIRRLRQEGKRVALVPTMGNLHDGHMKLVDEAKARADVVIVSIFVNPMQFDRPDDLVRYPRTLQEDCE
KLNKRKVDYVFAPAVEEIYPHGLEGQTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLIQPDIACFGEKDFQQLALIR
KMVADMSYDIEIVGVPIIRAKDGLALSSRNAYLTAEQRKIAPGLYNVMNSIAEKLIAGNRELQEIIAIAEQELNEKGFRA
DDIQIRDADTLLELTETSKRAVILAAAWLGQARLIDNQSVTLAQ

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=283, Percent_Identity=87.9858657243816, Blast_Score=514, Evalue=1e-147,
Organism=Saccharomyces cerevisiae, GI6322046, Length=292, Percent_Identity=37.6712328767123, Blast_Score=180, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 31858; Mature: 31858

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIIETLPLLRQHIRRLRQEGKRVALVPTMGNLHDGHMKLVDEAKARADVVIVSIFVNPM
CEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHCEEEEEEEECCC
QFDRPDDLVRYPRTLQEDCEKLNKRKVDYVFAPAVEEIYPHGLEGQTYVDVPGLSTMLEG
CCCCCHHHHHCCHHHHHHHHHHHHCCCCEEECCHHHHHCCCCCCCCEEECCCCHHHHHHC
ASRPGHFRGVSTIVSKLFNLIQPDIACFGEKDFQQLALIRKMVADMSYDIEIVGVPIIRA
CCCCCCCHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEC
KDGLALSSRNAYLTAEQRKIAPGLYNVMNSIAEKLIAGNRELQEIIAIAEQELNEKGFRA
CCCCEEECCCCEEEEHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
DDIQIRDADTLLELTETSKRAVILAAAWLGQARLIDNQSVTLAQ
CCEEEECHHHHHHHHHCCCCEEEEEEEHHCCCEEECCCCEEECC
>Mature Secondary Structure
MLIIETLPLLRQHIRRLRQEGKRVALVPTMGNLHDGHMKLVDEAKARADVVIVSIFVNPM
CEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHCEEEEEEEECCC
QFDRPDDLVRYPRTLQEDCEKLNKRKVDYVFAPAVEEIYPHGLEGQTYVDVPGLSTMLEG
CCCCCHHHHHCCHHHHHHHHHHHHCCCCEEECCHHHHHCCCCCCCCEEECCCCHHHHHHC
ASRPGHFRGVSTIVSKLFNLIQPDIACFGEKDFQQLALIRKMVADMSYDIEIVGVPIIRA
CCCCCCCHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEC
KDGLALSSRNAYLTAEQRKIAPGLYNVMNSIAEKLIAGNRELQEIIAIAEQELNEKGFRA
CCCCEEECCCCEEEEHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
DDIQIRDADTLLELTETSKRAVILAAAWLGQARLIDNQSVTLAQ
CCEEEECHHHHHHHHHCCCCEEEEEEEHHCCCEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA