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The map label for this gene is yfbT [H]

Identifier: 161353592

GI number: 161353592

Start: 2445897

End: 2446556

Strand: Reverse

Name: yfbT [H]

Synonym: STM2334

Alternate gene names: 161353592

Gene position: 2446556-2445897 (Counterclockwise)

Preceding gene: 16765662

Following gene: 16765660

Centisome position: 50.37

GC content: 57.73

Gene sequence:

>660_bases
GTGCAGTGTAAAGGTTTTCTGTTTGATCTGGATGGAACGTTGGTTGACTCATTACCTGCCGTTGAACGCGCGTGGTGTAG
CTGGGCCGATCGTTTTAACCTTGCTCATGATGAGGTGCTGGGCTTTATTCATGGCAAACAGGCGATCACCTCGTTGCGGC
ATTTTATGGCGGGTAAATCGGAGGCGGAAATTGCCGCTGAGTTTACGCGCCTGGAGCAAATAGAAGCCACTGAAACCGCA
GGGATCACCGCGCTGCCGGGGGCAGTCGATTTACTCAATCACCTGAATAAAGTGGGCATTCCGTGGGCTATCGTCACCTC
CGGTTCAATGCCGGTCGCGCGTGCGCGCCATCAGGTCGCGGGCCTTCCAGCGCCAGAGGTGTTTGTCACCGCCGAACGAG
TCAAACGCGGCAAACCGGAGCCGGATGCGTATTTGCTGGGCGCACAACTGCTTGGCCTGGCCCCTCAGGAGTGCGTCGTA
GTAGAAGATGCCCCGGCTGGCGTGCTGTCCGGGCTGGCTGCGGGCTGCCACGTCATTGCGGTCAATGCGCCGGCCGACAC
GCCGCGTCTGGCGGATGTTGATTTTGCGTTGGATAGCCTGACGCAATTATCGGTCGCTAAACAACCAAACGGCGATGTGG
TGGTGTTAAGAAAGACCTGA

Upstream 100 bases:

>100_bases
AAATACCAGCGGATGTTGAATGTCTGGCATGCCTGCCCGCGTCAGTACCACCTGAGCGCGAATGAAATCAATCAAATCAT
TAATGCCTGAGGAGGCTCGC

Downstream 100 bases:

>100_bases
TCATGATATCGCCCCGCTTTGGCGGGGCATATTTATGGCAGAATCGCGTTATCTTCTCATCTGACAAGGATATGTTGTGA
ACGGTGAATTGATTTGGGTT

Product: phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MQCKGFLFDLDGTLVDSLPAVERAWCSWADRFNLAHDEVLGFIHGKQAITSLRHFMAGKSEAEIAAEFTRLEQIEATETA
GITALPGAVDLLNHLNKVGIPWAIVTSGSMPVARARHQVAGLPAPEVFVTAERVKRGKPEPDAYLLGAQLLGLAPQECVV
VEDAPAGVLSGLAAGCHVIAVNAPADTPRLADVDFALDSLTQLSVAKQPNGDVVVLRKT

Sequences:

>Translated_219_residues
MQCKGFLFDLDGTLVDSLPAVERAWCSWADRFNLAHDEVLGFIHGKQAITSLRHFMAGKSEAEIAAEFTRLEQIEATETA
GITALPGAVDLLNHLNKVGIPWAIVTSGSMPVARARHQVAGLPAPEVFVTAERVKRGKPEPDAYLLGAQLLGLAPQECVV
VEDAPAGVLSGLAAGCHVIAVNAPADTPRLADVDFALDSLTQLSVAKQPNGDVVVLRKT
>Mature_219_residues
MQCKGFLFDLDGTLVDSLPAVERAWCSWADRFNLAHDEVLGFIHGKQAITSLRHFMAGKSEAEIAAEFTRLEQIEATETA
GITALPGAVDLLNHLNKVGIPWAIVTSGSMPVARARHQVAGLPAPEVFVTAERVKRGKPEPDAYLLGAQLLGLAPQECVV
VEDAPAGVLSGLAAGCHVIAVNAPADTPRLADVDFALDSLTQLSVAKQPNGDVVVLRKT

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrate glucose 6-phosphate [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=184, Percent_Identity=30.9782608695652, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI207113149, Length=208, Percent_Identity=27.4038461538462, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI87082080, Length=215, Percent_Identity=86.5116279069767, Blast_Score=361, Evalue=1e-101,
Organism=Escherichia coli, GI1789046, Length=189, Percent_Identity=30.1587301587302, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790151, Length=214, Percent_Identity=29.9065420560748, Blast_Score=64, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6321834, Length=228, Percent_Identity=31.5789473684211, Blast_Score=98, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321833, Length=228, Percent_Identity=30.2631578947368, Blast_Score=90, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322136, Length=191, Percent_Identity=34.5549738219895, Blast_Score=79, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6320905, Length=197, Percent_Identity=34.5177664974619, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20129151, Length=198, Percent_Identity=29.7979797979798, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 23222; Mature: 23222

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCKGFLFDLDGTLVDSLPAVERAWCSWADRFNLAHDEVLGFIHGKQAITSLRHFMAGKS
CCCCCEEEECCCHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
EAEIAAEFTRLEQIEATETAGITALPGAVDLLNHLNKVGIPWAIVTSGSMPVARARHQVA
HHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHC
GLPAPEVFVTAERVKRGKPEPDAYLLGAQLLGLAPQECVVVEDAPAGVLSGLAAGCHVIA
CCCCCHHEEEHHHHHCCCCCCCCEEHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCEEEE
VNAPADTPRLADVDFALDSLTQLSVAKQPNGDVVVLRKT
EECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECC
>Mature Secondary Structure
MQCKGFLFDLDGTLVDSLPAVERAWCSWADRFNLAHDEVLGFIHGKQAITSLRHFMAGKS
CCCCCEEEECCCHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
EAEIAAEFTRLEQIEATETAGITALPGAVDLLNHLNKVGIPWAIVTSGSMPVARARHQVA
HHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHC
GLPAPEVFVTAERVKRGKPEPDAYLLGAQLLGLAPQECVVVEDAPAGVLSGLAAGCHVIA
CCCCCHHEEEHHHHHCCCCCCCCEEHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCEEEE
VNAPADTPRLADVDFALDSLTQLSVAKQPNGDVVVLRKT
EECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 10493123 [H]