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The map label for this gene is tolC [H]

Identifier: 161353585

GI number: 161353585

Start: 3348573

End: 3350042

Strand: Direct

Name: tolC [H]

Synonym: STM3186

Alternate gene names: 161353585

Gene position: 3348573-3350042 (Clockwise)

Preceding gene: 16766480

Following gene: 16766487

Centisome position: 68.94

GC content: 52.11

Gene sequence:

>1470_bases
ATGAAGAAATTGCTCCCCATCCTTATCGGCCTGAGCCTGTCGGGGTTCAGCACACTAAGCCAGGCAGAGAACCTGATGCA
AGTTTATCAGCAAGCACGCCTGAGCAACCCGGAATTGCGTAAATCCGCTGCCGATCGCGATGCTGCATTCGAAAAAATTA
ACGAAGCGCGTAGTCCTTTACTGCCGCAACTGGGTTTAGGTGCCGACTACACCTACAGCAACGGTTATCGCGATGCGAAC
GGTATCAACTCCAATGAAACCAGCGCTTCTCTGCAATTAACGCAGACGCTATTTGATATGTCGAAATGGCGTGGGCTCAC
CCTGCAAGAAAAAGCAGCAGGCATTCAGGATGTCACCTATCAGACCGATCAGCAGACGCTGATCCTCAATACCGCGAACG
CGTATTTTAAGGTATTGAACGCTATTGATGTGCTTTCCTATACCCAGGCGCAAAAAGAGGCTATCTACCGTCAGTTAGAT
CAAACGACGCAACGTTTTAACGTGGGTCTGGTCGCCATTACCGACGTGCAAAACGCCCGTGCGCAATATGATACCGTACT
GGCGAATGAAGTGACCGCCCGCAACAACCTGGATAACGCGGTAGAAGAGCTGCGCCAGGTAACCGGCAATTATTACCCGG
AGCTGGCGTCGCTTAACGTCGAGCATTTTAAAACCGACAAACCCAAAGCTGTTAATGCGCTGTTGAAGGAAGCGGAAAAC
CGTAACCTGTCGCTGTTGCAGGCGCGTTTAAGTCAGGATCTGGCGCGCGAGCAAATCCGTCAGGCGCAGGATGGTCACCT
GCCGACGCTGAATTTAACGGCCTCAACCGGCATTTCTGATACCTCTTATAGCGGTTCTAAAACCAACTCCACCCAGTACG
ACGATAGCAACATGGGGCAGAATAAAATCGGCCTTAACTTCTCCCTGCCGCTGTATCAAGGTGGGATGGTTAACTCGCAG
GTAAAACAGGCGCAGTATAACTTCGTCGGCGCAAGCGAACAGCTGGAAAGCGCGCACCGTAGCGTGGTGCAGACCGTACG
TTCTTCCTTTAACAATATTAACGCCTCCATCAGCAGCATCAACGCGTATAAACAGGCGGTCGTTTCCGCGCAAAGTTCTT
TGGATGCCATGGAAGCCGGTTACTCGGTCGGTACACGTACCATTGTTGACGTACTGGATGCCACCACCACTCTGTATGAT
GCCAAGCAGCAACTGGCCAACGCGCGTTATACCTATTTGATTAATCAGTTAAATATCAAATATGCGCTCGGTACGCTGAA
CGAGCAGGATCTGCTCGCGCTTAACAGTACGTTGGGTAAACCTATCCCGACGTCGCCGGAAAGCGTAGCGCCGGAAACGC
CAGATCAGGATGCTGCCGCAGACGGTTATAATGCTCATAGCGCCGCGCCAGCAGTACAGCCGACCGCCGCTCGCGCCAAC
AGCAATAACGGCAATCCATTCCGGCATTGA

Upstream 100 bases:

>100_bases
ACGTAACGCCAACTTTTTGCAGTGGCGGATTCTGCTAGAATCAGCAATTATTTTTACAAATTGATCAGCGCTAAATACTG
CTTCACAACAAGGAATGCAA

Downstream 100 bases:

>100_bases
TAAGTTATTCGCTGGCGCTGCGCTTATCAGACCTGTGCCCTTGTAGGTCTGGTAAGCGCGGCGCTACCTGTCATAAAGCC
GCGCCTGAACGTAAGACAAC

Product: outer membrane channel protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MKKLLPILIGLSLSGFSTLSQAENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDAN
GINSNETSASLQLTQTLFDMSKWRGLTLQEKAAGIQDVTYQTDQQTLILNTANAYFKVLNAIDVLSYTQAQKEAIYRQLD
QTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEELRQVTGNYYPELASLNVEHFKTDKPKAVNALLKEAEN
RNLSLLQARLSQDLAREQIRQAQDGHLPTLNLTASTGISDTSYSGSKTNSTQYDDSNMGQNKIGLNFSLPLYQGGMVNSQ
VKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIVDVLDATTTLYD
AKQQLANARYTYLINQLNIKYALGTLNEQDLLALNSTLGKPIPTSPESVAPETPDQDAAADGYNAHSAAPAVQPTAARAN
SNNGNPFRH

Sequences:

>Translated_489_residues
MKKLLPILIGLSLSGFSTLSQAENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDAN
GINSNETSASLQLTQTLFDMSKWRGLTLQEKAAGIQDVTYQTDQQTLILNTANAYFKVLNAIDVLSYTQAQKEAIYRQLD
QTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEELRQVTGNYYPELASLNVEHFKTDKPKAVNALLKEAEN
RNLSLLQARLSQDLAREQIRQAQDGHLPTLNLTASTGISDTSYSGSKTNSTQYDDSNMGQNKIGLNFSLPLYQGGMVNSQ
VKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIVDVLDATTTLYD
AKQQLANARYTYLINQLNIKYALGTLNEQDLLALNSTLGKPIPTSPESVAPETPDQDAAADGYNAHSAAPAVQPTAARAN
SNNGNPFRH
>Mature_489_residues
MKKLLPILIGLSLSGFSTLSQAENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDAN
GINSNETSASLQLTQTLFDMSKWRGLTLQEKAAGIQDVTYQTDQQTLILNTANAYFKVLNAIDVLSYTQAQKEAIYRQLD
QTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEELRQVTGNYYPELASLNVEHFKTDKPKAVNALLKEAEN
RNLSLLQARLSQDLAREQIRQAQDGHLPTLNLTASTGISDTSYSGSKTNSTQYDDSNMGQNKIGLNFSLPLYQGGMVNSQ
VKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIVDVLDATTTLYD
AKQQLANARYTYLINQLNIKYALGTLNEQDLLALNSTLGKPIPTSPESVAPETPDQDAAADGYNAHSAAPAVQPTAARAN
SNNGNPFRH

Specific function: Required for proper expression of outer membrane protein genes such as ompF, nmpC, protein 2, hemolysin, colicin V, or colicin E1. May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=493, Percent_Identity=89.6551724137931, Blast_Score=862, Evalue=0.0,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53427; Mature: 53427

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLPILIGLSLSGFSTLSQAENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPL
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
LPQLGLGADYTYSNGYRDANGINSNETSASLQLTQTLFDMSKWRGLTLQEKAAGIQDVTY
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHCEE
QTDQQTLILNTANAYFKVLNAIDVLSYTQAQKEAIYRQLDQTTQRFNVGLVAITDVQNAR
ECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHH
AQYDTVLANEVTARNNLDNAVEELRQVTGNYYPELASLNVEHFKTDKPKAVNALLKEAEN
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHCCHHHHCCCCCHHHHHHHHHHCC
RNLSLLQARLSQDLAREQIRQAQDGHLPTLNLTASTGISDTSYSGSKTNSTQYDDSNMGQ
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
NKIGLNFSLPLYQGGMVNSQVKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSI
CCCCCEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
NAYKQAVVSAQSSLDAMEAGYSVGTRTIVDVLDATTTLYDAKQQLANARYTYLINQLNIK
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEHHHEEE
YALGTLNEQDLLALNSTLGKPIPTSPESVAPETPDQDAAADGYNAHSAAPAVQPTAARAN
EEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCC
SNNGNPFRH
CCCCCCCCC
>Mature Secondary Structure
MKKLLPILIGLSLSGFSTLSQAENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPL
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
LPQLGLGADYTYSNGYRDANGINSNETSASLQLTQTLFDMSKWRGLTLQEKAAGIQDVTY
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHCEE
QTDQQTLILNTANAYFKVLNAIDVLSYTQAQKEAIYRQLDQTTQRFNVGLVAITDVQNAR
ECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHH
AQYDTVLANEVTARNNLDNAVEELRQVTGNYYPELASLNVEHFKTDKPKAVNALLKEAEN
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHCCHHHHCCCCCHHHHHHHHHHCC
RNLSLLQARLSQDLAREQIRQAQDGHLPTLNLTASTGISDTSYSGSKTNSTQYDDSNMGQ
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
NKIGLNFSLPLYQGGMVNSQVKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSI
CCCCCEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
NAYKQAVVSAQSSLDAMEAGYSVGTRTIVDVLDATTTLYDAKQQLANARYTYLINQLNIK
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEHHHEEE
YALGTLNEQDLLALNSTLGKPIPTSPESVAPETPDQDAAADGYNAHSAAPAVQPTAARAN
EEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCC
SNNGNPFRH
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8801424 [H]