Click here to switch to the map view.

The map label for this gene is 218931067

Identifier: 218931067

GI number: 218931067

Start: 4609614

End: 4610567

Strand: Direct

Name: 218931067

Synonym: YPO4090

Alternate gene names: NA

Gene position: 4609614-4610567 (Clockwise)

Preceding gene: 218931066

Following gene: 218931068

Centisome position: 99.05

GC content: 50.52

Gene sequence:

>954_bases
ATGCTAATTCTGAATAAACAAAAAATTCTCGACAAGTTCGATGCGGATCGCATCACATTATTGCTCAAAGAGGGCTTTAT
TGCTTTTAGTCAGCAACGGGTCCAGATGCCGCCAGTACAGCATTTACTGTTTGATCAGGCCAATGGTGATTGCTGTATTA
AAAGTGGTTATTTACAGGGCGATGACCAGTTTGTCGTGAAGGTCTCCGGTGGATTTTATGATAACCCTGCTCAAGGATTA
GCCAGTAATCAAGGGGTGATGATGGCATTTTCGGCAAAAACCGGTGAACCACAAGCGATCTTACTGGATGAAGGCTGGCT
AACGGCGCTGCGCACAGCACTGGCCGGGCGAATTGTCGCCGAGCTTTGCGCGCCACAGCACATCAGCGCCCTTGGTATCG
TGGGGACAGGAATACAGGCGCGGCTGCATCTGATGTACCTGAAAAATGTGATGACTTGCCGCCAGCTATGGGTCTGGGGC
CGCAGTGAAACGGCATTAGAGGAGTATCGCCAATATGCGCAAGCAGAGGGCTTTGCAGTCAACACCACGTTGAATGCCGC
AGAGCTGGCCCATCACAGCCAATTTATTGTCACCACCACGCCAAGCCGGGAGCCTATTTTACAGGCTGAAGATATCCAGC
CGGGGACACATATTACGGCGGTTGGGGCAGATAGCGCGGGTAAGCACGAGCTCTCCGCCGAGTTAGTCGCGAGAGCCGAT
AAAATTCTGGTGGATTCAATCGCGCAATGCACCGATTTTGGCGAAGTTTCGTTAGCGTTTAAGCAAGGGCTGTTGGCTCA
TCACAACTTAACTGAGATCGGTTTAGCTTTAGCGCAAGGCATCCCTTTTAGAGAGAATGACCAACAGATTACCTTGGCGG
ATTTAACCGGGTTGGGGATTCAGGATGTGCAGATAGTGAAGGGGATTCTGGGAGATAAAAAGGGGGTGTTGTGA

Upstream 100 bases:

>100_bases
CGGCACTGAAATTGGCTCCGCAATGGCAAGGTAAGAAAGTGGCGGTGGTGTTGTGCGGTAAAAATATCGTGCTGGAGAAA
TATCTGGGAGCTGTCAGCGG

Downstream 100 bases:

>100_bases
ATCCCGGAGATATCAGTCGGTGATCGGGTTTCGGTTGATGGTGGTTTGGTGGTTTGGTGGTTTGGTGGTTTGAGTCGGTG
ATCGGGTTCGGTTGTTATGG

Product: ornithine cyclodeaminase

Products: L-proline; NH3

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MLILNKQKILDKFDADRITLLLKEGFIAFSQQRVQMPPVQHLLFDQANGDCCIKSGYLQGDDQFVVKVSGGFYDNPAQGL
ASNQGVMMAFSAKTGEPQAILLDEGWLTALRTALAGRIVAELCAPQHISALGIVGTGIQARLHLMYLKNVMTCRQLWVWG
RSETALEEYRQYAQAEGFAVNTTLNAAELAHHSQFIVTTTPSREPILQAEDIQPGTHITAVGADSAGKHELSAELVARAD
KILVDSIAQCTDFGEVSLAFKQGLLAHHNLTEIGLALAQGIPFRENDQQITLADLTGLGIQDVQIVKGILGDKKGVL

Sequences:

>Translated_317_residues
MLILNKQKILDKFDADRITLLLKEGFIAFSQQRVQMPPVQHLLFDQANGDCCIKSGYLQGDDQFVVKVSGGFYDNPAQGL
ASNQGVMMAFSAKTGEPQAILLDEGWLTALRTALAGRIVAELCAPQHISALGIVGTGIQARLHLMYLKNVMTCRQLWVWG
RSETALEEYRQYAQAEGFAVNTTLNAAELAHHSQFIVTTTPSREPILQAEDIQPGTHITAVGADSAGKHELSAELVARAD
KILVDSIAQCTDFGEVSLAFKQGLLAHHNLTEIGLALAQGIPFRENDQQITLADLTGLGIQDVQIVKGILGDKKGVL
>Mature_317_residues
MLILNKQKILDKFDADRITLLLKEGFIAFSQQRVQMPPVQHLLFDQANGDCCIKSGYLQGDDQFVVKVSGGFYDNPAQGL
ASNQGVMMAFSAKTGEPQAILLDEGWLTALRTALAGRIVAELCAPQHISALGIVGTGIQARLHLMYLKNVMTCRQLWVWG
RSETALEEYRQYAQAEGFAVNTTLNAAELAHHSQFIVTTTPSREPILQAEDIQPGTHITAVGADSAGKHELSAELVARAD
KILVDSIAQCTDFGEVSLAFKQGLLAHHNLTEIGLALAQGIPFRENDQQITLADLTGLGIQDVQIVKGILGDKKGVL

Specific function: Unknown

COG id: COG2423

COG function: function code E; Predicted ornithine cyclodeaminase, mu-crystallin homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ornithine cyclodeaminase family [H]

Homologues:

Organism=Homo sapiens, GI62241008, Length=213, Percent_Identity=27.6995305164319, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4503065, Length=213, Percent_Identity=27.6995305164319, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014334
- InterPro:   IPR016040
- InterPro:   IPR003462 [H]

Pfam domain/function: PF02423 OCD_Mu_crystall [H]

EC number: 4.3.1.12

Molecular weight: Translated: 34402; Mature: 34402

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILNKQKILDKFDADRITLLLKEGFIAFSQQRVQMPPVQHLLFDQANGDCCIKSGYLQG
CEEECHHHHHHHCCCCCEEEEEHHCHHHHHHCCCCCCHHHHHHHHCCCCCEEEECCEECC
DDQFVVKVSGGFYDNPAQGLASNQGVMMAFSAKTGEPQAILLDEGWLTALRTALAGRIVA
CCEEEEEECCCCCCCCHHCCCCCCCEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHH
ELCAPQHISALGIVGTGIQARLHLMYLKNVMTCRQLWVWGRSETALEEYRQYAQAEGFAV
HHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEE
NTTLNAAELAHHSQFIVTTTPSREPILQAEDIQPGTHITAVGADSAGKHELSAELVARAD
ECCCCHHHHHHCCEEEEEECCCCCCCEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
KILVDSIAQCTDFGEVSLAFKQGLLAHHNLTEIGLALAQGIPFRENDQQITLADLTGLGI
HHHHHHHHHHCCCCHHHHHHHHCHHHCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCC
QDVQIVKGILGDKKGVL
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLILNKQKILDKFDADRITLLLKEGFIAFSQQRVQMPPVQHLLFDQANGDCCIKSGYLQG
CEEECHHHHHHHCCCCCEEEEEHHCHHHHHHCCCCCCHHHHHHHHCCCCCEEEECCEECC
DDQFVVKVSGGFYDNPAQGLASNQGVMMAFSAKTGEPQAILLDEGWLTALRTALAGRIVA
CCEEEEEECCCCCCCCHHCCCCCCCEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHH
ELCAPQHISALGIVGTGIQARLHLMYLKNVMTCRQLWVWGRSETALEEYRQYAQAEGFAV
HHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEE
NTTLNAAELAHHSQFIVTTTPSREPILQAEDIQPGTHITAVGADSAGKHELSAELVARAD
ECCCCHHHHHHCCEEEEEECCCCCCCEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
KILVDSIAQCTDFGEVSLAFKQGLLAHHNLTEIGLALAQGIPFRENDQQITLADLTGLGI
HHHHHHHHHHCCCCHHHHHHHHCHHHCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCC
QDVQIVKGILGDKKGVL
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-ornithine

Specific reaction: L-ornithine = L-proline + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]