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The map label for this gene is selA [H]

Identifier: 218931038

GI number: 218931038

Start: 4571507

End: 4572895

Strand: Reverse

Name: selA [H]

Synonym: YPO4054

Alternate gene names: 218931038

Gene position: 4572895-4571507 (Counterclockwise)

Preceding gene: 218931039

Following gene: 218931036

Centisome position: 98.26

GC content: 54.79

Gene sequence:

>1389_bases
ATGAGCGCAGAACCACACCCATTATATCGCCAGTTACCGGCCATTGATCGCTTACTGAATGAGCCTGAAATGGCCCCTTT
ATTGGCGGAGTATGGCCCCGTTCTTTTGGCCGATACCCTACGTCAATTACAGGCAGAAGCTCGTGAATATATCGGTCAAT
TTCATACTCTGGCTGATTGGTGTGCGGACTGGCCTGCCGCTTTACGTCAACGATTGAATCAACGGCAACCCGCGTTAAAA
CCTGTGTTTAATCTTACTGGCACGGTGCTGCACACCAATTTGGGCCGTGCACCGCTGGCAGAATCTGCTATCGCGGCGGT
GACCGATGCCATGCGAAGTGCGGTCACCTTGGAATACTCCTTAGAGGGCGCGGGCCGTGGGCACCGTGATCGGGCTGTCG
CCGATTTACTCTGTGCCCTGACCGGTGCGGAAGATGCCTGTATCGTCAATAACAATGCGGCGGCGGTCTTCTTGTTGTTA
ACGGTCATGGCGGCGGGCAAGCAAGTCGTGGTCTCCCGTGGTGAACTGGTCGAGATTGGCGGTGCGTTTCGTATTCCTGA
TGTCATGCGTCAGGCAGGGTGTGAGCTGGTCGAAGTGGGTACCACGAACCGAACACATCTGAAAGATTATCGGCAGGCCA
TCAATGAAAATACGGGTCTGCTGATGAAAGTTCATACCAGCAATTACAGTATCGAGGGTTTCACGGCCGCAGTATCCGAA
CAGCAACTGGCGGCATTGGGGCAAGAGTGTTCCATCCCGACCGCGACCGATTTAGGCAGTGGTTCGCTGGTGGATATGAC
CCGTTACGGTTTACCCGCCGAGCCCATGCCACAACAGTTGATTGCGGCAGGCGTAGATTTAGTGACCTTCTCCGGTGATA
AACTGTTAGGTGGGCCGCAAGCGGGGATCATTCTCGGTAAAAAACAGTGGATTGAGCGGTTACAGCAACATCCGCTGAAG
CGAGCATTGCGGGCCGATAAAATGACACTGGCAGCTTTGGACGCCACCTTGCGCCTCTATCAGCAGCCAGATCGGTTGGT
TGAACAACTGCCATCTCTGCGGCTACTGACCCGCCCCGCCTCAGAGATTGCCGCGTGTGCACAACGCCTGCTGGCCCCAC
TGATTGCCTGTTATGGCACAGATTTCACTTTGGATATTGAATCATGTTGGTCACAAATTGGCAGTGGTTCGCTGCCGGTT
GATCGCTTGCCCAGTTGGGCGCTGACGTTTACGCCTAAAGATGGGCGCGGTAGTACATTGGAAGCCTTAACGGCGCGTTG
GCGCACACTGACGAAGCCGGTCATTGGTCGTGTGGCTGATGGGCGTTTGTGGCTGGATTTACGCTGTCTGGAGGATGAGG
CGGCGTTGCTAAGGGAATTGGCATCATGA

Upstream 100 bases:

>100_bases
TAAGGTCAATGACCAATCAGTGATGGGGGTGAGGGCAATCAACGCACAGGCAACTCGACGTATGGCGGGTATATCGTTTA
ATTAATTTGTTTGAGTGACT

Downstream 100 bases:

>100_bases
TTATTGTCACCGCAGGCCATGTCGATCATGGCAAAACCACACTTTTACAGGCCATTACCGGGGTTAATGCGGATCGGTTG
CCGGAAGAGAAGCAGCGGGG

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSAEPHPLYRQLPAIDRLLNEPEMAPLLAEYGPVLLADTLRQLQAEAREYIGQFHTLADWCADWPAALRQRLNQRQPALK
PVFNLTGTVLHTNLGRAPLAESAIAAVTDAMRSAVTLEYSLEGAGRGHRDRAVADLLCALTGAEDACIVNNNAAAVFLLL
TVMAAGKQVVVSRGELVEIGGAFRIPDVMRQAGCELVEVGTTNRTHLKDYRQAINENTGLLMKVHTSNYSIEGFTAAVSE
QQLAALGQECSIPTATDLGSGSLVDMTRYGLPAEPMPQQLIAAGVDLVTFSGDKLLGGPQAGIILGKKQWIERLQQHPLK
RALRADKMTLAALDATLRLYQQPDRLVEQLPSLRLLTRPASEIAACAQRLLAPLIACYGTDFTLDIESCWSQIGSGSLPV
DRLPSWALTFTPKDGRGSTLEALTARWRTLTKPVIGRVADGRLWLDLRCLEDEAALLRELAS

Sequences:

>Translated_462_residues
MSAEPHPLYRQLPAIDRLLNEPEMAPLLAEYGPVLLADTLRQLQAEAREYIGQFHTLADWCADWPAALRQRLNQRQPALK
PVFNLTGTVLHTNLGRAPLAESAIAAVTDAMRSAVTLEYSLEGAGRGHRDRAVADLLCALTGAEDACIVNNNAAAVFLLL
TVMAAGKQVVVSRGELVEIGGAFRIPDVMRQAGCELVEVGTTNRTHLKDYRQAINENTGLLMKVHTSNYSIEGFTAAVSE
QQLAALGQECSIPTATDLGSGSLVDMTRYGLPAEPMPQQLIAAGVDLVTFSGDKLLGGPQAGIILGKKQWIERLQQHPLK
RALRADKMTLAALDATLRLYQQPDRLVEQLPSLRLLTRPASEIAACAQRLLAPLIACYGTDFTLDIESCWSQIGSGSLPV
DRLPSWALTFTPKDGRGSTLEALTARWRTLTKPVIGRVADGRLWLDLRCLEDEAALLRELAS
>Mature_461_residues
SAEPHPLYRQLPAIDRLLNEPEMAPLLAEYGPVLLADTLRQLQAEAREYIGQFHTLADWCADWPAALRQRLNQRQPALKP
VFNLTGTVLHTNLGRAPLAESAIAAVTDAMRSAVTLEYSLEGAGRGHRDRAVADLLCALTGAEDACIVNNNAAAVFLLLT
VMAAGKQVVVSRGELVEIGGAFRIPDVMRQAGCELVEVGTTNRTHLKDYRQAINENTGLLMKVHTSNYSIEGFTAAVSEQ
QLAALGQECSIPTATDLGSGSLVDMTRYGLPAEPMPQQLIAAGVDLVTFSGDKLLGGPQAGIILGKKQWIERLQQHPLKR
ALRADKMTLAALDATLRLYQQPDRLVEQLPSLRLLTRPASEIAACAQRLLAPLIACYGTDFTLDIESCWSQIGSGSLPVD
RLPSWALTFTPKDGRGSTLEALTARWRTLTKPVIGRVADGRLWLDLRCLEDEAALLRELAS

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=461, Percent_Identity=69.1973969631237, Blast_Score=602, Evalue=1e-173,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 50209; Mature: 50078

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAEPHPLYRQLPAIDRLLNEPEMAPLLAEYGPVLLADTLRQLQAEAREYIGQFHTLADW
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
CADWPAALRQRLNQRQPALKPVFNLTGTVLHTNLGRAPLAESAIAAVTDAMRSAVTLEYS
HCCCHHHHHHHHHHCCCHHHHHHHCCHHHEECCCCCCCHHHHHHHHHHHHHHHHEEEEEE
LEGAGRGHRDRAVADLLCALTGAEDACIVNNNAAAVFLLLTVMAAGKQVVVSRGELVEIG
ECCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCEEECCCCEEEEC
GAFRIPDVMRQAGCELVEVGTTNRTHLKDYRQAINENTGLLMKVHTSNYSIEGFTAAVSE
CCCCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHH
QQLAALGQECSIPTATDLGSGSLVDMTRYGLPAEPMPQQLIAAGVDLVTFSGDKLLGGPQ
HHHHHCCCCCCCCCCCCCCCCCEEHHHHCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCC
AGIILGKKQWIERLQQHPLKRALRADKMTLAALDATLRLYQQPDRLVEQLPSLRLLTRPA
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCEEHHCCH
SEIAACAQRLLAPLIACYGTDFTLDIESCWSQIGSGSLPVDRLPSWALTFTPKDGRGSTL
HHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCHHHCCCCEEEECCCCCCCCHH
EALTARWRTLTKPVIGRVADGRLWLDLRCLEDEAALLRELAS
HHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHCC
>Mature Secondary Structure 
SAEPHPLYRQLPAIDRLLNEPEMAPLLAEYGPVLLADTLRQLQAEAREYIGQFHTLADW
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
CADWPAALRQRLNQRQPALKPVFNLTGTVLHTNLGRAPLAESAIAAVTDAMRSAVTLEYS
HCCCHHHHHHHHHHCCCHHHHHHHCCHHHEECCCCCCCHHHHHHHHHHHHHHHHEEEEEE
LEGAGRGHRDRAVADLLCALTGAEDACIVNNNAAAVFLLLTVMAAGKQVVVSRGELVEIG
ECCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCEEECCCCEEEEC
GAFRIPDVMRQAGCELVEVGTTNRTHLKDYRQAINENTGLLMKVHTSNYSIEGFTAAVSE
CCCCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHH
QQLAALGQECSIPTATDLGSGSLVDMTRYGLPAEPMPQQLIAAGVDLVTFSGDKLLGGPQ
HHHHHCCCCCCCCCCCCCCCCCEEHHHHCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCC
AGIILGKKQWIERLQQHPLKRALRADKMTLAALDATLRLYQQPDRLVEQLPSLRLLTRPA
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCEEHHCCH
SEIAACAQRLLAPLIACYGTDFTLDIESCWSQIGSGSLPVDRLPSWALTFTPKDGRGSTL
HHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCHHHCCCCEEEECCCCCCCCHH
EALTARWRTLTKPVIGRVADGRLWLDLRCLEDEAALLRELAS
HHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA