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The map label for this gene is ispD [H]

Identifier: 218930379

GI number: 218930379

Start: 3749432

End: 3750157

Strand: Reverse

Name: ispD [H]

Synonym: YPO3361

Alternate gene names: 218930379

Gene position: 3750157-3749432 (Counterclockwise)

Preceding gene: 218930380

Following gene: 218930378

Centisome position: 80.58

GC content: 50.69

Gene sequence:

>726_bases
ATGAGTAACTTCGCAGTTTCCCTTCCTGAAGTGATCGCTGTATTACCGGCTGCGGGTATTGGTAGCCGTATGTTGGTGGA
TTGCCCTAAGCAGTATTTAACTGTGGGGGGCAAAACAATCATTGAACATGCTATTTTTTCTTTGCTTCACCACCCACGAA
TTCAGCGGGTTATCGTTGTGATCCATCCGCAGGACACACAATTCTCTAGGTTGTCCGTTGCGCAGGATCCACGTATCAGT
ACAGTTTACGGTGGCGATCAACGGGCTAACTCCGTGATGGCGGGTTTACAATTGGCAGGGCAGGCTGAATGGGTGTTAGT
TCATGATGCGGCACGCCCCTGTTTGCACCTTGATGATCTCAGCCGGCTGTTATCGATTACCGAATGCAGTCAGGTGGGGG
GAATTCTGGCGGCCCCTGTGCGTGATACGATGAAACGTGCCGAGCCGGGTATTCAAGCCATCGCTCATACGGTGGATCGT
CAGGACCTGTGGCATGCGCTGACGCCTCAACTTTTCCCGCTAGAATTATTAAAATTGTGCTTATCCCGTGCGTTAAGAGA
AGGGGTGGCGGTGACTGATGAGGCCTCTGCATTAGAGCATTGCGGTTATCATCCGATATTGGTTACCGGCCGTTCTGATA
ATATTAAAGTGACGCGCCCAGAAGATCTGGCATTGGCGGAGTTTTATTTAACCCAGCGGCAGTCTCTCAATAACGACAGT
CTCTGA

Upstream 100 bases:

>100_bases
GGGCATGATTAAGCCCGGCGAAAGTTTCTATCGTCTGGTTCCTGACCAATCCAGACGCAATGCGGGTACCCCTTCGACAC
AAAATAACGCGCAATAAATA

Downstream 100 bases:

>100_bases
ATAATGACGGTCTCTAAATAACGATAGCCGCTAAACAGCGACAAGTCAGTGAGATGGGTAAGCGGAAGTCGTGAACGTTA
ATCAAGACTAACGGCACTGC

Product: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

Products: NA

Alternate protein names: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MSNFAVSLPEVIAVLPAAGIGSRMLVDCPKQYLTVGGKTIIEHAIFSLLHHPRIQRVIVVIHPQDTQFSRLSVAQDPRIS
TVYGGDQRANSVMAGLQLAGQAEWVLVHDAARPCLHLDDLSRLLSITECSQVGGILAAPVRDTMKRAEPGIQAIAHTVDR
QDLWHALTPQLFPLELLKLCLSRALREGVAVTDEASALEHCGYHPILVTGRSDNIKVTRPEDLALAEFYLTQRQSLNNDS
L

Sequences:

>Translated_241_residues
MSNFAVSLPEVIAVLPAAGIGSRMLVDCPKQYLTVGGKTIIEHAIFSLLHHPRIQRVIVVIHPQDTQFSRLSVAQDPRIS
TVYGGDQRANSVMAGLQLAGQAEWVLVHDAARPCLHLDDLSRLLSITECSQVGGILAAPVRDTMKRAEPGIQAIAHTVDR
QDLWHALTPQLFPLELLKLCLSRALREGVAVTDEASALEHCGYHPILVTGRSDNIKVTRPEDLALAEFYLTQRQSLNNDS
L
>Mature_240_residues
SNFAVSLPEVIAVLPAAGIGSRMLVDCPKQYLTVGGKTIIEHAIFSLLHHPRIQRVIVVIHPQDTQFSRLSVAQDPRIST
VYGGDQRANSVMAGLQLAGQAEWVLVHDAARPCLHLDDLSRLLSITECSQVGGILAAPVRDTMKRAEPGIQAIAHTVDRQ
DLWHALTPQLFPLELLKLCLSRALREGVAVTDEASALEHCGYHPILVTGRSDNIKVTRPEDLALAEFYLTQRQSLNNDSL

Specific function: Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) [H]

COG id: COG1211

COG function: function code I; 4-diphosphocytidyl-2-methyl-D-erithritol synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispD family [H]

Homologues:

Organism=Escherichia coli, GI1789104, Length=223, Percent_Identity=68.1614349775785, Blast_Score=330, Evalue=4e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001228
- InterPro:   IPR018294 [H]

Pfam domain/function: PF01128 IspD [H]

EC number: =2.7.7.60 [H]

Molecular weight: Translated: 26402; Mature: 26271

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS01295 ISPD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFAVSLPEVIAVLPAAGIGSRMLVDCPKQYLTVGGKTIIEHAIFSLLHHPRIQRVIVV
CCCCCCHHHHHHHHHCCCCCCCHHHHHCCHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEE
IHPQDTQFSRLSVAQDPRISTVYGGDQRANSVMAGLQLAGQAEWVLVHDAARPCLHLDDL
ECCCCCCHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
SRLLSITECSQVGGILAAPVRDTMKRAEPGIQAIAHTVDRQDLWHALTPQLFPLELLKLC
HHHHHHHHHHHHCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LSRALREGVAVTDEASALEHCGYHPILVTGRSDNIKVTRPEDLALAEFYLTQRQSLNNDS
HHHHHHCCCCCCCHHHHHHHCCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHCCCCCC
L
C
>Mature Secondary Structure 
SNFAVSLPEVIAVLPAAGIGSRMLVDCPKQYLTVGGKTIIEHAIFSLLHHPRIQRVIVV
CCCCCHHHHHHHHHCCCCCCCHHHHHCCHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEE
IHPQDTQFSRLSVAQDPRISTVYGGDQRANSVMAGLQLAGQAEWVLVHDAARPCLHLDDL
ECCCCCCHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
SRLLSITECSQVGGILAAPVRDTMKRAEPGIQAIAHTVDRQDLWHALTPQLFPLELLKLC
HHHHHHHHHHHHCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LSRALREGVAVTDEASALEHCGYHPILVTGRSDNIKVTRPEDLALAEFYLTQRQSLNNDS
HHHHHHCCCCCCCHHHHHHHCCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHCCCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA