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The map label for this gene is dhaK [H]

Identifier: 218930368

GI number: 218930368

Start: 3736573

End: 3737574

Strand: Reverse

Name: dhaK [H]

Synonym: YPO3350

Alternate gene names: 218930368

Gene position: 3737574-3736573 (Counterclockwise)

Preceding gene: 218930369

Following gene: 218930367

Centisome position: 80.31

GC content: 49.7

Gene sequence:

>1002_bases
ATGAATCGAATTATTAACGATCCGGATCAGGTTGTGGAAGAGGCGATAAAAGGCTATTTAGCGGCTTATCCACATTTTTT
TGCTAAAACCGCGCATGAGAAAGTATTGAAGTATCCAGAGATACCCCTCCAAGGGAAAGTAGGCGTAGTGACCGGGGGCG
GTTCTGGCCATGAACCCGCGTTTCTGGGCTATATCGGTAAAAATATGCTGGATGCCGTAGCGGTTGGTGAGATCTTCTCC
TCCCCGGCGGCTGGGGCATTTTTAGAAGCGTTTAAAGTTGCCGACGGCGGTGCGGGTGTTGCTTGTCTGTACGGTAATTA
CGCCGGGGACAATATGAACGTCAAAATGGCGGCAAAAAAAGCCGAGGCCATGGGGATAAGGGTTCGCACCGTGGTTGCTA
ATGATGATGTGGCCTCTGCACCACCGTCGGAAAGAGAGAAACGCCGAGGTGTGGCGGGTGAAATTTTTATGTGGAAAGTG
GGCGCAGCAGCGGCGTCTCAAGGCTACGCTCTGGATAATGTCATAGAGGTTGCTCAGAAAGCGATTGATCACTGCCGTTC
AATCGGCGTGGGCTTAACCTCCTGTACCATCCCGGCGGTGGGTAAACCTAATTTCTCGATAGAAGACGGCATGATGGAAG
TGGGGATTGGTCATCACGGAGAACCGGGTATTCGGGTTGAGTCGCTACAGAATGCACATCAGATGGCAAAGACCATGGTG
GATTTGGTGGTCGCTGATAGGCCGTTTAGCCAAGGCGATGAGGTAGCGGTGTTGATCTCTGGGCTCGGTGCCACGCCGAC
CATTGAGCTGTATATCTATTATGCAGAAGTCGCCAAATTATTAGAGGCGCAGGGGATAACAATATATCGCCCTTATATTG
GTAATTATTTTACCTCGCTAGACATGATGGGGGTCACGCTGACGCTGATGAAACTGGATGATGAATTAAAATCTTTAATT
GATGTACCCACTCATTCATTAGGCTTAACCCAGTTGGAGTAA

Upstream 100 bases:

>100_bases
ATACCATCCAATAGTGCTGTCGTTGCGCGCGCTAAATTACCGCGGCATCCAGTTAACTCACCCACTGTTTTTATTTATTT
TCCATTTTAACGAGATTGCT

Downstream 100 bases:

>100_bases
GGGATTATGAAGGCATTGTTGATAACCGATGGATCTATAAAAGATAAGTGCATAACCGACGGTACCCCGATCATTGAAGA
GATGGCCAATACGATCCTCG

Product: putative dihydroxyacetone kinase

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MNRIINDPDQVVEEAIKGYLAAYPHFFAKTAHEKVLKYPEIPLQGKVGVVTGGGSGHEPAFLGYIGKNMLDAVAVGEIFS
SPAAGAFLEAFKVADGGAGVACLYGNYAGDNMNVKMAAKKAEAMGIRVRTVVANDDVASAPPSEREKRRGVAGEIFMWKV
GAAAASQGYALDNVIEVAQKAIDHCRSIGVGLTSCTIPAVGKPNFSIEDGMMEVGIGHHGEPGIRVESLQNAHQMAKTMV
DLVVADRPFSQGDEVAVLISGLGATPTIELYIYYAEVAKLLEAQGITIYRPYIGNYFTSLDMMGVTLTLMKLDDELKSLI
DVPTHSLGLTQLE

Sequences:

>Translated_333_residues
MNRIINDPDQVVEEAIKGYLAAYPHFFAKTAHEKVLKYPEIPLQGKVGVVTGGGSGHEPAFLGYIGKNMLDAVAVGEIFS
SPAAGAFLEAFKVADGGAGVACLYGNYAGDNMNVKMAAKKAEAMGIRVRTVVANDDVASAPPSEREKRRGVAGEIFMWKV
GAAAASQGYALDNVIEVAQKAIDHCRSIGVGLTSCTIPAVGKPNFSIEDGMMEVGIGHHGEPGIRVESLQNAHQMAKTMV
DLVVADRPFSQGDEVAVLISGLGATPTIELYIYYAEVAKLLEAQGITIYRPYIGNYFTSLDMMGVTLTLMKLDDELKSLI
DVPTHSLGLTQLE
>Mature_333_residues
MNRIINDPDQVVEEAIKGYLAAYPHFFAKTAHEKVLKYPEIPLQGKVGVVTGGGSGHEPAFLGYIGKNMLDAVAVGEIFS
SPAAGAFLEAFKVADGGAGVACLYGNYAGDNMNVKMAAKKAEAMGIRVRTVVANDDVASAPPSEREKRRGVAGEIFMWKV
GAAAASQGYALDNVIEVAQKAIDHCRSIGVGLTSCTIPAVGKPNFSIEDGMMEVGIGHHGEPGIRVESLQNAHQMAKTMV
DLVVADRPFSQGDEVAVLISGLGATPTIELYIYYAEVAKLLEAQGITIYRPYIGNYFTSLDMMGVTLTLMKLDDELKSLI
DVPTHSLGLTQLE

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=330, Percent_Identity=33.6363636363636, Blast_Score=189, Evalue=4e-48,
Organism=Escherichia coli, GI87081857, Length=355, Percent_Identity=37.7464788732394, Blast_Score=237, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI17565018, Length=321, Percent_Identity=31.1526479750779, Blast_Score=184, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6323570, Length=335, Percent_Identity=32.5373134328358, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6321055, Length=300, Percent_Identity=33, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 35451; Mature: 35451

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIINDPDQVVEEAIKGYLAAYPHFFAKTAHEKVLKYPEIPLQGKVGVVTGGGSGHEPA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCH
FLGYIGKNMLDAVAVGEIFSSPAAGAFLEAFKVADGGAGVACLYGNYAGDNMNVKMAAKK
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEHHH
AEAMGIRVRTVVANDDVASAPPSEREKRRGVAGEIFMWKVGAAAASQGYALDNVIEVAQK
HHHCCEEEEEEEECCCCCCCCCCHHHHHCCCCCEEEEEEECCHHCCCCCHHHHHHHHHHH
AIDHCRSIGVGLTSCTIPAVGKPNFSIEDGMMEVGIGHHGEPGIRVESLQNAHQMAKTMV
HHHHHHHHCCCHHHEECCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHH
DLVVADRPFSQGDEVAVLISGLGATPTIELYIYYAEVAKLLEAQGITIYRPYIGNYFTSL
HHHHCCCCCCCCCCEEEEEECCCCCCEEEEEEEHHHHHHHHHHCCCEEECCCHHHHHHHH
DMMGVTLTLMKLDDELKSLIDVPTHSLGLTQLE
HHHHHEEEEHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNRIINDPDQVVEEAIKGYLAAYPHFFAKTAHEKVLKYPEIPLQGKVGVVTGGGSGHEPA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCH
FLGYIGKNMLDAVAVGEIFSSPAAGAFLEAFKVADGGAGVACLYGNYAGDNMNVKMAAKK
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEHHH
AEAMGIRVRTVVANDDVASAPPSEREKRRGVAGEIFMWKVGAAAASQGYALDNVIEVAQK
HHHCCEEEEEEEECCCCCCCCCCHHHHHCCCCCEEEEEEECCHHCCCCCHHHHHHHHHHH
AIDHCRSIGVGLTSCTIPAVGKPNFSIEDGMMEVGIGHHGEPGIRVESLQNAHQMAKTMV
HHHHHHHHCCCHHHEECCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHH
DLVVADRPFSQGDEVAVLISGLGATPTIELYIYYAEVAKLLEAQGITIYRPYIGNYFTSL
HHHHCCCCCCCCCCEEEEEECCCCCCEEEEEEEHHHHHHHHHHCCCEEECCCHHHHHHHH
DMMGVTLTLMKLDDELKSLIDVPTHSLGLTQLE
HHHHHEEEEHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]