Click here to switch to the map view.

The map label for this gene is dinP [H]

Identifier: 218930258

GI number: 218930258

Start: 3596749

End: 3597807

Strand: Reverse

Name: dinP [H]

Synonym: YPO3231

Alternate gene names: 218930258

Gene position: 3597807-3596749 (Counterclockwise)

Preceding gene: 218930260

Following gene: 218930256

Centisome position: 77.31

GC content: 49.29

Gene sequence:

>1059_bases
ATGCGAAAAATTATTCATGTCGATATGGATTGCTTCTTCGCGGCAGTAGAAATGCGCGACGACCCTCGCCTGCGTGATAT
CCCCCTTGCGATTGGTGGCAGTAAGGAGCGGCGTGGCGTGATCAGTACCGCTAATTATCCCGCTCGGCGTTATGGTGTTC
GCAGCGCTATGCCAACGGCGATGGCGTTTAAACTCTGCCCACAGTTAACATTGCTGCCTGGTAGAATGGCGGCTTATAAA
GAGGCCTCGCAGCATATTCGCGAAATTTTTGCCCGTTATACTCCATTGATTGAACCACTGTCATTGGATGAGGCCTATTT
GGATGTTTCTGATAGCTTGGCGTGCGGTGGCTCTGCAACATTAATCGCTCAAGAGATCCGCCAGTCTATCGCTAGTGAGC
TGAACCTGACAGCCTCCGCGGGGATTGCCCCGATAAAATTTCTTGCCAAAATCGCCTCAGAGCTGAATAAACCTAATGGC
CAGTATGTGATTACACCGAATCAGATCCAGCCCTTCCTACAGGATTTACCGCTGAGTAAAATTCCCGGTGTTGGTGCCGT
CACCGCCAAACGTTTACAGGCGCTGGGGTTGGTAACCTGTGGCGATATACAAAAATATCCATTGGCAGAGTTGTTAAAAC
ATTTTGGTAAGTTTGGTCGCGTATTGTGGGAGCGTAGTCACGGTATTGATGAACGTGAAATATCCCCAGATCGTCTACGT
AAATCCGTTGGTGTGGAGAAAACACTGGCCGAGGATATTTATGACTGGGAAAGTTGTGAGGCGTTGATCGAAGAACTTTA
TCTTGAACTGGAAACTCGTTTACGTAAGGTAAAGCCGAGCCTACACATTGCCCGGCAGGGCGTTAAGCTAAAATTTCATG
ATTTTCAGCAGACCACGCAAGAACACACATGGCCAGTATTGAATAAAGTAGATTTACTGGAGATTGCCCACGCCGCATGG
CATGAACGGCGGGCCGAGCGGGGAGTCCGTTTGGTCGGGCTGCATGTTACGTTGCTGGATCCACAACTTGAGCGGCAATT
ATTGCTTGATTGGGGCTAG

Upstream 100 bases:

>100_bases
CCTTGCATGAACTCATCGGTACGACTATAGGTTAGGAGAATCTTGAATCCTTTTATTTTGACTGTATACTTATACAGCTG
TTTGTTGTGTGGGGGATTTC

Downstream 100 bases:

>100_bases
CTATTGCACGGTGTAAATAACACCCATTTGCCCGAATCACTGGTGTGTGTCAGTTCATCGGGCTTGTCTTGTAACGGTAA
TTATTTTGGCTATTAAAGCC

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTAMAFKLCPQLTLLPGRMAAYK
EASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSATLIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNG
QYVITPNQIQPFLQDLPLSKIPGVGAVTAKRLQALGLVTCGDIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLR
KSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPSLHIARQGVKLKFHDFQQTTQEHTWPVLNKVDLLEIAHAAW
HERRAERGVRLVGLHVTLLDPQLERQLLLDWG

Sequences:

>Translated_352_residues
MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTAMAFKLCPQLTLLPGRMAAYK
EASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSATLIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNG
QYVITPNQIQPFLQDLPLSKIPGVGAVTAKRLQALGLVTCGDIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLR
KSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPSLHIARQGVKLKFHDFQQTTQEHTWPVLNKVDLLEIAHAAW
HERRAERGVRLVGLHVTLLDPQLERQLLLDWG
>Mature_352_residues
MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTAMAFKLCPQLTLLPGRMAAYK
EASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSATLIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNG
QYVITPNQIQPFLQDLPLSKIPGVGAVTAKRLQALGLVTCGDIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLR
KSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPSLHIARQGVKLKFHDFQQTTQEHTWPVLNKVDLLEIAHAAW
HERRAERGVRLVGLHVTLLDPQLERQLLLDWG

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI7705344, Length=383, Percent_Identity=33.9425587467363, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI84043967, Length=324, Percent_Identity=29.9382716049383, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI7706681, Length=325, Percent_Identity=30.1538461538462, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI154350220, Length=251, Percent_Identity=34.2629482071713, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI5729982, Length=120, Percent_Identity=40, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1786425, Length=349, Percent_Identity=76.2177650429799, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI1787432, Length=219, Percent_Identity=25.5707762557078, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193205700, Length=404, Percent_Identity=32.1782178217822, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17537959, Length=259, Percent_Identity=30.8880308880309, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI193205702, Length=349, Percent_Identity=26.647564469914, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI115534089, Length=164, Percent_Identity=31.0975609756098, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324921, Length=300, Percent_Identity=29, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19923006, Length=328, Percent_Identity=30.1829268292683, Blast_Score=158, Evalue=5e-39,
Organism=Drosophila melanogaster, GI21355641, Length=283, Percent_Identity=31.4487632508834, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24644984, Length=283, Percent_Identity=31.4487632508834, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24668444, Length=120, Percent_Identity=35.8333333333333, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39657; Mature: 39657

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTA
CCCEEEECHHHHHHHHHCCCCCCCEECCEEECCCCCCCCCEECCCCCHHHHHHHHHHHHH
MAFKLCPQLTLLPGRMAAYKEASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSAT
HHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCHH
LIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNGQYVITPNQIQPFLQDLPLSK
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHCCHHH
IPGVGAVTAKRLQALGLVTCGDIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLR
CCCCCHHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPSLHIARQGVKLKFHDFQQTTQ
HHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEHHHHHHHH
EHTWPVLNKVDLLEIAHAAWHERRAERGVRLVGLHVTLLDPQLERQLLLDWG
HCCCHHHCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECHHHHHHHHCCCC
>Mature Secondary Structure
MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTA
CCCEEEECHHHHHHHHHCCCCCCCEECCEEECCCCCCCCCEECCCCCHHHHHHHHHHHHH
MAFKLCPQLTLLPGRMAAYKEASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSAT
HHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCHH
LIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNGQYVITPNQIQPFLQDLPLSK
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHCCHHH
IPGVGAVTAKRLQALGLVTCGDIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLR
CCCCCHHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPSLHIARQGVKLKFHDFQQTTQ
HHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEHHHHHHHH
EHTWPVLNKVDLLEIAHAAWHERRAERGVRLVGLHVTLLDPQLERQLLLDWG
HCCCHHHCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA