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The map label for this gene is ycgR [H]

Identifier: 218930247

GI number: 218930247

Start: 3583468

End: 3584226

Strand: Reverse

Name: ycgR [H]

Synonym: YPO3220

Alternate gene names: 218930247

Gene position: 3584226-3583468 (Counterclockwise)

Preceding gene: 218930248

Following gene: 218930246

Centisome position: 77.02

GC content: 43.08

Gene sequence:

>759_bases
ATGGGGCCAGTGAGCGAAACGTCTAAAGAGCAATTTGTTAAAAAAAATAAACTAGCGATCTGTGCAATTCTTCGGGATTT
ACAGAAGAACGATACTGCCGTGATGGTTACCCATGCTCGAGGACAATTTATTAGCCGTATTCTGGATATACAGCCTGAGA
CTAATCAGTTTATTTTCGATTTCGGCAGTGTAGAAAACGAAAATGTTTTGGCTCTTGGTGCGGAGCAACTCACGATTATT
GTTGAACCTACGGGTGCCAAAATTGAATTCACCTGTAACAAGCTGAAACATGTCGAATATTTGTCACTACCCGCCTTCAG
TTCTGCCATCCCGGAACAGCTCTATTTCATTCAGCGACGGGAATATTTTCGTGTCAGTATTCCGCAATGGCCAGCTTATT
ATTGTAGTGGGAAATTCCCTGACGGCACTCAGTATAAATATACATTGGCCGACATCTCCTTGGGTGGAATGGGTTTATAT
GCCATGAAAGGTAGCGAATTTCCGCTCCAGGGATGCAGTGTTCTGCGAGATGCAGCGGTAGATTTATGTGGTTTTGGCCT
CTTTAAATTAGATCTGCAATTTATCCGGGCGCTCGATAAACAAGTGGTTAATAACAAGGGCGAAATGCTGACAGTGCAAC
GTTTGAGTTTTAAATTCTTGCGCTTAAGTCCTATTCAAGAGAAAGGCTTACAGCGAGCCATTTTTGAACTGGAAAAACAG
CAAACAGCTAAGGCGAGGAAATTTCAGGAAGGCCTGTAG

Upstream 100 bases:

>100_bases
AAACATTTAAGTAATTCTGTTAGTTGCCGATAACCTCTTTGTTATTTATACATTTTTGATGATAATCTGAGCAGATAGAC
TGATAAATTAAGAATAGGGA

Downstream 100 bases:

>100_bases
CCTCACTATATTCTGTAGCTTCACTCTATAGAGTAGCGGTCTGTCGCTTGTATGATGCGTTTTATCATTATTTACAAGCC
CACAGGGAGCGCCTCTGAGG

Product: hypothetical protein

Products: NA

Alternate protein names: Cyclic di-GMP binding protein YcgR [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MGPVSETSKEQFVKKNKLAICAILRDLQKNDTAVMVTHARGQFISRILDIQPETNQFIFDFGSVENENVLALGAEQLTII
VEPTGAKIEFTCNKLKHVEYLSLPAFSSAIPEQLYFIQRREYFRVSIPQWPAYYCSGKFPDGTQYKYTLADISLGGMGLY
AMKGSEFPLQGCSVLRDAAVDLCGFGLFKLDLQFIRALDKQVVNNKGEMLTVQRLSFKFLRLSPIQEKGLQRAIFELEKQ
QTAKARKFQEGL

Sequences:

>Translated_252_residues
MGPVSETSKEQFVKKNKLAICAILRDLQKNDTAVMVTHARGQFISRILDIQPETNQFIFDFGSVENENVLALGAEQLTII
VEPTGAKIEFTCNKLKHVEYLSLPAFSSAIPEQLYFIQRREYFRVSIPQWPAYYCSGKFPDGTQYKYTLADISLGGMGLY
AMKGSEFPLQGCSVLRDAAVDLCGFGLFKLDLQFIRALDKQVVNNKGEMLTVQRLSFKFLRLSPIQEKGLQRAIFELEKQ
QTAKARKFQEGL
>Mature_251_residues
GPVSETSKEQFVKKNKLAICAILRDLQKNDTAVMVTHARGQFISRILDIQPETNQFIFDFGSVENENVLALGAEQLTIIV
EPTGAKIEFTCNKLKHVEYLSLPAFSSAIPEQLYFIQRREYFRVSIPQWPAYYCSGKFPDGTQYKYTLADISLGGMGLYA
MKGSEFPLQGCSVLRDAAVDLCGFGLFKLDLQFIRALDKQVVNNKGEMLTVQRLSFKFLRLSPIQEKGLQRAIFELEKQQ
TAKARKFQEGL

Specific function: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility [H]

COG id: COG5581

COG function: function code M; Predicted glycosyltransferase

Gene ontology:

Cell location: Bacterial flagellum basal body [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain [H]

Homologues:

Organism=Escherichia coli, GI1787443, Length=241, Percent_Identity=40.6639004149378, Blast_Score=196, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009875
- InterPro:   IPR009926 [H]

Pfam domain/function: PF07238 PilZ; PF07317 YcgR [H]

EC number: NA

Molecular weight: Translated: 28526; Mature: 28395

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPVSETSKEQFVKKNKLAICAILRDLQKNDTAVMVTHARGQFISRILDIQPETNQFIFD
CCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHCCCCCCCEEEEE
FGSVENENVLALGAEQLTIIVEPTGAKIEFTCNKLKHVEYLSLPAFSSAIPEQLYFIQRR
ECCCCCCCEEEECCCEEEEEECCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHCC
EYFRVSIPQWPAYYCSGKFPDGTQYKYTLADISLGGMGLYAMKGSEFPLQGCSVLRDAAV
CEEEEECCCCCCEEECCCCCCCCCEEEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHHH
DLCGFGLFKLDLQFIRALDKQVVNNKGEMLTVQRLSFKFLRLSPIQEKGLQRAIFELEKQ
HHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHEEHEEECCHHHHHHHHHHHHHHHH
QTAKARKFQEGL
HHHHHHHHHHCC
>Mature Secondary Structure 
GPVSETSKEQFVKKNKLAICAILRDLQKNDTAVMVTHARGQFISRILDIQPETNQFIFD
CCCCCCHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHCCCCCCCEEEEE
FGSVENENVLALGAEQLTIIVEPTGAKIEFTCNKLKHVEYLSLPAFSSAIPEQLYFIQRR
ECCCCCCCEEEECCCEEEEEECCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHCC
EYFRVSIPQWPAYYCSGKFPDGTQYKYTLADISLGGMGLYAMKGSEFPLQGCSVLRDAAV
CEEEEECCCCCCEEECCCCCCCCCEEEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHHH
DLCGFGLFKLDLQFIRALDKQVVNNKGEMLTVQRLSFKFLRLSPIQEKGLQRAIFELEKQ
HHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHEEHEEECCHHHHHHHHHHHHHHHH
QTAKARKFQEGL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA