Click here to switch to the map view.

The map label for this gene is yciA [H]

Identifier: 218929293

GI number: 218929293

Start: 2471565

End: 2472014

Strand: Reverse

Name: yciA [H]

Synonym: YPO2195

Alternate gene names: 218929293

Gene position: 2472014-2471565 (Counterclockwise)

Preceding gene: 218929294

Following gene: 218929292

Centisome position: 53.12

GC content: 47.56

Gene sequence:

>450_bases
ATGACTCAGGAACAACAACTATCTGGCGGTGAACTTTCATTACCTAACGGTGAGTTAGTGCTTCGCACTCTGGCAATGCC
AGCAGACACCAACGCCAACGGGGATATATTTGGCGGTTGGTTGATGTCTCAAATGGATATTGGTGGCGCTATCCAAGCTA
AAGAAATTGCACAGGGTCGCGTTGTGACGGTTCGTGTTGATGGCATGACGTTTCTTAAGCCTGTGGCTGTTGGTGACGTT
GTTTGCTGCTATGCACGCTGTATTAAAACCGGGCACAGCTCTATCACCATTAACATTGAAGTATGGGTAAAAAAGGTTTC
TTCTGAGCCAATAGGGCAGCGTTATCGTGCTACTGAAGCGGTATTCACCTATGTCGCGGTTGATGATGCGGGTAAACCCC
GTGGATTACCGAGCGGTAAAGGTAATTTCGAAGTAGGTGCGACTCAATAA

Upstream 100 bases:

>100_bases
GAAGAGCAGAAGAAGTCTTAAATAAACGTTATTTTGATGCTCACTGAACGCTCAGTGGGCCGCCCTTAGTCAGTGGATTA
ACTTTTAAAAGCAGACAGAA

Downstream 100 bases:

>100_bases
TGAATGTGAGAGTATTGATCAAACAAGAAGGGCCGCAAAAGCGGCCCTGAGGTTGGTGACAGTCTTATTTAATTCAGAGA
CTGTAAACAATATTGTGTAA

Product: acyl-CoA thioester hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MTQEQQLSGGELSLPNGELVLRTLAMPADTNANGDIFGGWLMSQMDIGGAIQAKEIAQGRVVTVRVDGMTFLKPVAVGDV
VCCYARCIKTGHSSITINIEVWVKKVSSEPIGQRYRATEAVFTYVAVDDAGKPRGLPSGKGNFEVGATQ

Sequences:

>Translated_149_residues
MTQEQQLSGGELSLPNGELVLRTLAMPADTNANGDIFGGWLMSQMDIGGAIQAKEIAQGRVVTVRVDGMTFLKPVAVGDV
VCCYARCIKTGHSSITINIEVWVKKVSSEPIGQRYRATEAVFTYVAVDDAGKPRGLPSGKGNFEVGATQ
>Mature_148_residues
TQEQQLSGGELSLPNGELVLRTLAMPADTNANGDIFGGWLMSQMDIGGAIQAKEIAQGRVVTVRVDGMTFLKPVAVGDVV
CCYARCIKTGHSSITINIEVWVKKVSSEPIGQRYRATEAVFTYVAVDDAGKPRGLPSGKGNFEVGATQ

Specific function: Catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA [H]

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1787506, Length=125, Percent_Identity=82.4, Blast_Score=223, Evalue=4e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 15860; Mature: 15729

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQEQQLSGGELSLPNGELVLRTLAMPADTNANGDIFGGWLMSQMDIGGAIQAKEIAQGR
CCCCCCCCCCEEECCCCCEEEEEECCCCCCCCCCCEEEHEEEECCCCCCCEEHHHHCCCC
VVTVRVDGMTFLKPVAVGDVVCCYARCIKTGHSSITINIEVWVKKVSSEPIGQRYRATEA
EEEEEECCEEEECHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCHHHHHHEE
VFTYVAVDDAGKPRGLPSGKGNFEVGATQ
EEEEEEECCCCCCCCCCCCCCCEEECCCC
>Mature Secondary Structure 
TQEQQLSGGELSLPNGELVLRTLAMPADTNANGDIFGGWLMSQMDIGGAIQAKEIAQGR
CCCCCCCCCEEECCCCCEEEEEECCCCCCCCCCCEEEHEEEECCCCCCCEEHHHHCCCC
VVTVRVDGMTFLKPVAVGDVVCCYARCIKTGHSSITINIEVWVKKVSSEPIGQRYRATEA
EEEEEECCEEEECHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCHHHHHHEE
VFTYVAVDDAGKPRGLPSGKGNFEVGATQ
EEEEEEECCCCCCCCCCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]