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The map label for this gene is znuA

Identifier: 218929168

GI number: 218929168

Start: 2339124

End: 2340080

Strand: Direct

Name: znuA

Synonym: YPO2061

Alternate gene names: 218929168

Gene position: 2339124-2340080 (Clockwise)

Preceding gene: 218929165

Following gene: 218929169

Centisome position: 50.26

GC content: 44.72

Gene sequence:

>957_bases
ATGTTACATAAAAATAAATGGCTAAAACAGGCAATGCTCGCCAGCGCACTTTTACTGGCAAATCCCTTTAATCTGGCTTC
GGCGGCCGTTGTTACATCAATACGCCCGCTAGGTTTTATTGCTGCCGCCATTGCAGATGGGGTGCTGCCAACCGAGGTTT
TATTACCTGATGGCGCATCTCCCCACGATTATGCGCTTCGTCCATCGGATGTCCAGCGGTTACGTAGCGCCGAATTGGTT
ATTTGGGTCGGGCCGGAAATGGAAGCATTTCTATCAAAACCATTAACGCAAGTCGCTGAAAATAAACAGATCGCTTTATC
ACAGTTACCTTCTGTTACACCATTGTTGATGAAGAGTGATGAACATGATGAGGCTGAAGAGGGCGAGAGTGGACATCATC
ATGATCATGCTAAAGATAATCCGACTGATGACCACCATCACGGTGAGTATAACATGCATATTTGGCTGTCACCGGCCATC
GCTAAACAGGCTGCAATTGCTATACACGACAGATTATTGGAACTTACGCCACAAAATAAGGACAAATTAGATGCGAACCT
GCGTCGATTCGAGTATCAACTAGCGCAAAATGAAAAAAATATTGTTACTATGCTTAAGCCTGTCCAAGGTAAGGGATATT
TTGTTTTTCATGACGCCTATGGCTACTTTGAAAATCACTTTGGCTTGAGTCCATTAGGGCATTTTACAGTCAATCCTGAA
ATACAACCTGGTGCGCAGCGTTTACATCAAATTCGAACACAGTTGGTTGAGCATAAGGCGGTATGCGTTTTTGCTGAACC
ACAATTCAGGCCAGCGGTCATTAATGCTGTTGCCAAGGGAACTAACGTGCGTTCTGGCACACTGGATCCTTTAGGGAGCG
GTATAGTATTGGACAAGGACAGCTATGTGAACTTTTTGTCTCAGTTGTCGAACCAATATGTGAGCTGCCTGAAGTAA

Upstream 100 bases:

>100_bases
TATTAAGCGTTACCAATATGGGCATCATGATTATATTTGCAGAATCTAGTGAATGTTATAATATTACGCTTTACCCATCA
AAACGTCGAGAATTCGTATT

Downstream 100 bases:

>100_bases
GATTAAAAGGATACTCATAAGTGCAGCAGATAGTCAGAACTATCACTTTAGCATATAACAATCTTCCTCGACCCCATCGC
ATCATGTTGGGGTCGTTGAC

Product: high-affinity zinc transporter periplasmic component

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MLHKNKWLKQAMLASALLLANPFNLASAAVVTSIRPLGFIAAAIADGVLPTEVLLPDGASPHDYALRPSDVQRLRSAELV
IWVGPEMEAFLSKPLTQVAENKQIALSQLPSVTPLLMKSDEHDEAEEGESGHHHDHAKDNPTDDHHHGEYNMHIWLSPAI
AKQAAIAIHDRLLELTPQNKDKLDANLRRFEYQLAQNEKNIVTMLKPVQGKGYFVFHDAYGYFENHFGLSPLGHFTVNPE
IQPGAQRLHQIRTQLVEHKAVCVFAEPQFRPAVINAVAKGTNVRSGTLDPLGSGIVLDKDSYVNFLSQLSNQYVSCLK

Sequences:

>Translated_318_residues
MLHKNKWLKQAMLASALLLANPFNLASAAVVTSIRPLGFIAAAIADGVLPTEVLLPDGASPHDYALRPSDVQRLRSAELV
IWVGPEMEAFLSKPLTQVAENKQIALSQLPSVTPLLMKSDEHDEAEEGESGHHHDHAKDNPTDDHHHGEYNMHIWLSPAI
AKQAAIAIHDRLLELTPQNKDKLDANLRRFEYQLAQNEKNIVTMLKPVQGKGYFVFHDAYGYFENHFGLSPLGHFTVNPE
IQPGAQRLHQIRTQLVEHKAVCVFAEPQFRPAVINAVAKGTNVRSGTLDPLGSGIVLDKDSYVNFLSQLSNQYVSCLK
>Mature_318_residues
MLHKNKWLKQAMLASALLLANPFNLASAAVVTSIRPLGFIAAAIADGVLPTEVLLPDGASPHDYALRPSDVQRLRSAELV
IWVGPEMEAFLSKPLTQVAENKQIALSQLPSVTPLLMKSDEHDEAEEGESGHHHDHAKDNPTDDHHHGEYNMHIWLSPAI
AKQAAIAIHDRLLELTPQNKDKLDANLRRFEYQLAQNEKNIVTMLKPVQGKGYFVFHDAYGYFENHFGLSPLGHFTVNPE
IQPGAQRLHQIRTQLVEHKAVCVFAEPQFRPAVINAVAKGTNVRSGTLDPLGSGIVLDKDSYVNFLSQLSNQYVSCLK

Specific function: Involved in the high-affinity zinc uptake transport system

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family

Homologues:

Organism=Escherichia coli, GI87081990, Length=293, Percent_Identity=64.8464163822526, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ZNUA_YERPE (Q8ZEU2)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AE0251
- RefSeq:   NP_669558.1
- RefSeq:   NP_993245.1
- RefSeq:   YP_002347043.1
- ProteinModelPortal:   Q8ZEU2
- SMR:   Q8ZEU2
- GeneID:   1147196
- GeneID:   1174899
- GeneID:   2766421
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO2061
- KEGG:   ypk:y2249
- KEGG:   ypm:YP_1904
- HOGENOM:   HBG731008
- OMA:   KHEHKHD
- ProtClustDB:   PRK09545
- BioCyc:   YPES187410:Y2249-MONOMER
- BioCyc:   YPES214092:YPO2061-MONOMER
- InterPro:   IPR006127

Pfam domain/function: PF01297 SBP_bac_9

EC number: NA

Molecular weight: Translated: 35245; Mature: 35245

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHKNKWLKQAMLASALLLANPFNLASAAVVTSIRPLGFIAAAIADGVLPTEVLLPDGAS
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCC
PHDYALRPSDVQRLRSAELVIWVGPEMEAFLSKPLTQVAENKQIALSQLPSVTPLLMKSD
CCCCCCCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHCCCC
EHDEAEEGESGHHHDHAKDNPTDDHHHGEYNMHIWLSPAIAKQAAIAIHDRLLELTPQNK
CCCCHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCCCCC
DKLDANLRRFEYQLAQNEKNIVTMLKPVQGKGYFVFHDAYGYFENHFGLSPLGHFTVNPE
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCHHHHHCCCCCCCCCEEECCC
IQPGAQRLHQIRTQLVEHKAVCVFAEPQFRPAVINAVAKGTNVRSGTLDPLGSGIVLDKD
CCHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEECCH
SYVNFLSQLSNQYVSCLK
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLHKNKWLKQAMLASALLLANPFNLASAAVVTSIRPLGFIAAAIADGVLPTEVLLPDGAS
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCC
PHDYALRPSDVQRLRSAELVIWVGPEMEAFLSKPLTQVAENKQIALSQLPSVTPLLMKSD
CCCCCCCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHCCCC
EHDEAEEGESGHHHDHAKDNPTDDHHHGEYNMHIWLSPAIAKQAAIAIHDRLLELTPQNK
CCCCHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCCCCC
DKLDANLRRFEYQLAQNEKNIVTMLKPVQGKGYFVFHDAYGYFENHFGLSPLGHFTVNPE
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCHHHHHCCCCCCCCCEEECCC
IQPGAQRLHQIRTQLVEHKAVCVFAEPQFRPAVINAVAKGTNVRSGTLDPLGSGIVLDKD
CCHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEECCH
SYVNFLSQLSNQYVSCLK
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430