Click here to switch to the map view.

The map label for this gene is int [H]

Identifier: 218929033

GI number: 218929033

Start: 2169863

End: 2171125

Strand: Reverse

Name: int [H]

Synonym: YPO1917

Alternate gene names: 218929033

Gene position: 2171125-2169863 (Counterclockwise)

Preceding gene: 218929034

Following gene: 218929028

Centisome position: 46.65

GC content: 52.65

Gene sequence:

>1263_bases
ATGTCCCTTACCGACGCAAAAATCCGCACCCTCAAGCCTTCTGATAAACCCTTTAAAGTCTCCGATTCTCACGGTCTGTA
TCTGCTGGTCAAGCCGGGTGGCTCCCGCCACTGGTATCTCAAATACCGTATTAGCGGTAAAGAATCCCGCATTGCGCTGG
GTGCCTATCCAGCCATCTCCCTGTCTGATGCGCGACAGCAACGTGAAGGTATCCGTAAAATGCTGGCGCTGAATATCAAC
CCGGTACAGCAGCGGGCTGCTGAACGTGGCTCACGAACACCGGAGAAAGTTTTTAAAAACGTGGCGCTGGCGTGGCATAA
AAGTAACAGGAAATGGTCGCAGAACACCGCCGACCGTCTGCTTGCCAGCCTGAACAATCACATCTTTCCGGTCATCGGGA
ACCTACCTGTATCAGAACTTAAACCCCGTCATTTCATTGACCTGCTGAAAGGGATCGAGGAAAAAGGTCTGCTGGAGGTT
GCGTCCCGCACACGGCAGCACCTGAGTAACATAATGCGCCATGCGGTCCATCAGGAGTTAATCGATACGAACCCTGCAGC
AAACCTTGGCGGCGTGACCACACCTCCTGTCAGACGGCACTATCCTGCCCTGCCGCTGGAGCGGCTGCCTGAACTGCTTG
AACGTATTGGGGCATATCATCAGGGCCGTGAACTGACCCGGCATGCCGTTCTGCTGATGCTGCATGTGTTCATTCGCTCC
AGTGAACTGCGTTTCGCCCGCTGGTCAGAGATTGATTTCACAAACCGAGTCTGGACGATACCCGCGACGCGAGAACCCAT
TATTGGCGTGCGTTATTCCGGCCGCGGGGCAAAAATGCGAATGCCGCATATCGTCCCCCTCTCAGAACAGTCCATCGCCA
TTCTGAAACAGATTAAGGATATCACCGGTAATAATGAACTGATCTTCCCCGGCGACCATAACCCGTATAAGCCAATGTGT
GAAAACACGGTCAATAAGGCACTGCGGGTGATGGGTTACGACACGAAAAAGGATATCTGCGGTCACGGCTTCCGGGCAAT
GGCATGCAGTGCGCTGATGGAATCGGGTTTATGGGCAAAGGACGCAGTAGAACGCCAGATGAGTCATCAGGAGCACAATA
CCGTGCGCATGGCTTATATTCATAAGGCAGAGCACCTAGAAGCCCGCAAAGCGATGATGCAGTGGTGGTCGGATTATCTG
GAAGCATGCCGAGAATCTTATGCACCGCCTTATACAATTGGTAAAAATAAGTTTATCCCATAG

Upstream 100 bases:

>100_bases
GAAAACTCTTCTCGGTGCATTTTGATTTTACCCTACGCATCGGGAAAAATTGGTGGTCAAATCTGGGGTCAGGTTAGTTC
GATAATGGAGTGACCCCCAT

Downstream 100 bases:

>100_bases
TATACTAACGAATCCCACACTCTGGCAAATTACCACCACCTCCACAGGAGGTGGTTCTATATAGACTTTTATCAACTTCA
TGACGAAAAACACCTATTTT

Product: integrase

Products: NA

Alternate protein names: Int(P4) [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MSLTDAKIRTLKPSDKPFKVSDSHGLYLLVKPGGSRHWYLKYRISGKESRIALGAYPAISLSDARQQREGIRKMLALNIN
PVQQRAAERGSRTPEKVFKNVALAWHKSNRKWSQNTADRLLASLNNHIFPVIGNLPVSELKPRHFIDLLKGIEEKGLLEV
ASRTRQHLSNIMRHAVHQELIDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRHAVLLMLHVFIRS
SELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRGAKMRMPHIVPLSEQSIAILKQIKDITGNNELIFPGDHNPYKPMC
ENTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAKDAVERQMSHQEHNTVRMAYIHKAEHLEARKAMMQWWSDYL
EACRESYAPPYTIGKNKFIP

Sequences:

>Translated_420_residues
MSLTDAKIRTLKPSDKPFKVSDSHGLYLLVKPGGSRHWYLKYRISGKESRIALGAYPAISLSDARQQREGIRKMLALNIN
PVQQRAAERGSRTPEKVFKNVALAWHKSNRKWSQNTADRLLASLNNHIFPVIGNLPVSELKPRHFIDLLKGIEEKGLLEV
ASRTRQHLSNIMRHAVHQELIDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRHAVLLMLHVFIRS
SELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRGAKMRMPHIVPLSEQSIAILKQIKDITGNNELIFPGDHNPYKPMC
ENTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAKDAVERQMSHQEHNTVRMAYIHKAEHLEARKAMMQWWSDYL
EACRESYAPPYTIGKNKFIP
>Mature_419_residues
SLTDAKIRTLKPSDKPFKVSDSHGLYLLVKPGGSRHWYLKYRISGKESRIALGAYPAISLSDARQQREGIRKMLALNINP
VQQRAAERGSRTPEKVFKNVALAWHKSNRKWSQNTADRLLASLNNHIFPVIGNLPVSELKPRHFIDLLKGIEEKGLLEVA
SRTRQHLSNIMRHAVHQELIDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRHAVLLMLHVFIRSS
ELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRGAKMRMPHIVPLSEQSIAILKQIKDITGNNELIFPGDHNPYKPMCE
NTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAKDAVERQMSHQEHNTVRMAYIHKAEHLEARKAMMQWWSDYLE
ACRESYAPPYTIGKNKFIP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=407, Percent_Identity=33.1695331695332, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1788690, Length=401, Percent_Identity=30.4239401496259, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI145693166, Length=411, Percent_Identity=32.1167883211679, Blast_Score=195, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 47987; Mature: 47856

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTDAKIRTLKPSDKPFKVSDSHGLYLLVKPGGSRHWYLKYRISGKESRIALGAYPAIS
CCCCCCHHEEECCCCCCEEEECCCCEEEEEECCCCEEEEEEEEECCCCCEEEEECCCCCC
LSDARQQREGIRKMLALNINPVQQRAAERGSRTPEKVFKNVALAWHKSNRKWSQNTADRL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
LASLNNHIFPVIGNLPVSELKPRHFIDLLKGIEEKGLLEVASRTRQHLSNIMRHAVHQEL
HHHHCCCEEEEECCCCHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRHAVLLMLHVFIRS
HCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHC
SELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRGAKMRMPHIVPLSEQSIAILKQIKD
CCCCEEECCCCCCCCCEEECCCCCCCEEEEEECCCCCCCCCCEECCCCCHHHHHHHHHHH
ITGNNELIFPGDHNPYKPMCENTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAK
CCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCCCHH
DAVERQMSHQEHNTVRMAYIHKAEHLEARKAMMQWWSDYLEACRESYAPPYTIGKNKFIP
HHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCC
>Mature Secondary Structure 
SLTDAKIRTLKPSDKPFKVSDSHGLYLLVKPGGSRHWYLKYRISGKESRIALGAYPAIS
CCCCCHHEEECCCCCCEEEECCCCEEEEEECCCCEEEEEEEEECCCCCEEEEECCCCCC
LSDARQQREGIRKMLALNINPVQQRAAERGSRTPEKVFKNVALAWHKSNRKWSQNTADRL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
LASLNNHIFPVIGNLPVSELKPRHFIDLLKGIEEKGLLEVASRTRQHLSNIMRHAVHQEL
HHHHCCCEEEEECCCCHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRHAVLLMLHVFIRS
HCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHC
SELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRGAKMRMPHIVPLSEQSIAILKQIKD
CCCCEEECCCCCCCCCEEECCCCCCCEEEEEECCCCCCCCCCEECCCCCHHHHHHHHHHH
ITGNNELIFPGDHNPYKPMCENTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAK
CCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCCCHH
DAVERQMSHQEHNTVRMAYIHKAEHLEARKAMMQWWSDYLEACRESYAPPYTIGKNKFIP
HHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]