Click here to switch to the map view.

The map label for this gene is irp8 [C]

Identifier: 218929031

GI number: 218929031

Start: 2167057

End: 2168337

Strand: Direct

Name: irp8 [C]

Synonym: YPO1915

Alternate gene names: 218929031

Gene position: 2167057-2168337 (Clockwise)

Preceding gene: 218929030

Following gene: 218929032

Centisome position: 46.57

GC content: 59.48

Gene sequence:

>1281_bases
ATGAGTGATGTTCAGTCGAATGTGAAACCGCTGACGTTGACGACCGGGCGGGTGATTTTTGCTATTGCCGGCGTCTATGT
GACGCAGAGTCTGGTATCGGCGCTGTCTATGCAGTCCTTACCCGCGCTGGTGCGCGCTGCTGGCGGTTCGCTGGCGCTTG
CCGGTGCGACAACCCTGTTTATGCTGCCCTGGGCGCTGAAGTTTATTTGGGCGCCGTGGATCGAGCGCTGGCGGCTTCCG
CCCGGTAGCCAGGAACGCCGTTCCCGCATGTTAATCCTGCGTGGTCAGGTCGCGCTAGCGGCGATCCTGACTATTGCCGC
AGCGATTGGCTGGTTTGGGCGAGAAGGGGGATTCCCCGATACGCAAATCGTCGCGTTATTTGTTCTGTTTATGGTGGCAG
GCACGGTCGCCTCCACCATTGATATCGCCAGCGACGGCTTTTGCGTCGATCAACTGACCCGCACGGGTTACGGCTGGGGA
AACAGCGTGCAGGTCGGCGGCAGCTATCTGGGAATGATGTGCGGCGGCGGGGTGTTCCTGATGCTGTCGGCGGCATCCGG
CTGGCCTGTCGCCATGCTGATGATGGCGGTGCTGATTATGGCGCTGTCACTCCCGCTGTGGCGCATTACGGAGCCGACGC
GAACAGCGACTATCCCGCATGTTCCGGCGTTAGGTTATGCGCTAAGGAGGAAGCAGGCGCGCCTGGGCTTACTGCTGGTA
TTGATGCTGAATTCAGGCATGCGGTTTGTGCTGCCTCTTCTGGCACCGCTGTTGTTGGATCATGGGTTGAGCATGTCCGC
ATTGGGCGCGCTGTTCAGCGGCGGCAATATTGCAGCGGGCATAGCAGGAACGCTGGCCGGCGGATTGCTGATGAAATACA
CCTCACCCGGCAGAGCGCTGTTGACGGCTTATGGCGTCCAGGGGATCGCGCTGCTGGCGGTGGTGATGACGCTCATGATG
GCGCCGGGTCATCTGCTGCTGCCGATTCTCCAGTGTCTGGTCATTGTCCAGTCCATTTCGCTGGCCTGCGCGCTGGTCTG
TCTTTACGCCACGCTGATGTCGCTTTCATCGCCTTTGCAGGCCGGTGTCGACTTCACCCTCTTTCAATGTACTGACGCGG
CAATCGCCATTCTGGCAGGCGTTATCGGTGGCGTTGTTGCTCAACATTTTGGCTATGCGGCCTGCTTCCTGTTTGCCGGG
GCATTCACGTTGCTGGCGGCGTGGGTTGCTTATATCCGGCTGCATTCGGCAAGAGAACTGATGACAAGCGCAATTGATTG
A

Upstream 100 bases:

>100_bases
TTGCTCTCACATCATGGACGTTATCAGGCGCTGTGGCAGGCGCAAATGGCCGCGCGCGTGTGGCGCGACGACGGGGTTTC
CGCGTCTGGAGAGTGGGTGC

Downstream 100 bases:

>100_bases
TCCGGGAATAACACAGAGAGGTAAGGGATGAAAATCAGTGAATTTCTACATCTGGCGTTACCAGAGGAACAATGGCTACC
GACGATTTCTGGCGTTTTAC

Product: putative signal transducer

Products: NA

Alternate protein names: ORF3 [H]

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MSDVQSNVKPLTLTTGRVIFAIAGVYVTQSLVSALSMQSLPALVRAAGGSLALAGATTLFMLPWALKFIWAPWIERWRLP
PGSQERRSRMLILRGQVALAAILTIAAAIGWFGREGGFPDTQIVALFVLFMVAGTVASTIDIASDGFCVDQLTRTGYGWG
NSVQVGGSYLGMMCGGGVFLMLSAASGWPVAMLMMAVLIMALSLPLWRITEPTRTATIPHVPALGYALRRKQARLGLLLV
LMLNSGMRFVLPLLAPLLLDHGLSMSALGALFSGGNIAAGIAGTLAGGLLMKYTSPGRALLTAYGVQGIALLAVVMTLMM
APGHLLLPILQCLVIVQSISLACALVCLYATLMSLSSPLQAGVDFTLFQCTDAAIAILAGVIGGVVAQHFGYAACFLFAG
AFTLLAAWVAYIRLHSARELMTSAID

Sequences:

>Translated_426_residues
MSDVQSNVKPLTLTTGRVIFAIAGVYVTQSLVSALSMQSLPALVRAAGGSLALAGATTLFMLPWALKFIWAPWIERWRLP
PGSQERRSRMLILRGQVALAAILTIAAAIGWFGREGGFPDTQIVALFVLFMVAGTVASTIDIASDGFCVDQLTRTGYGWG
NSVQVGGSYLGMMCGGGVFLMLSAASGWPVAMLMMAVLIMALSLPLWRITEPTRTATIPHVPALGYALRRKQARLGLLLV
LMLNSGMRFVLPLLAPLLLDHGLSMSALGALFSGGNIAAGIAGTLAGGLLMKYTSPGRALLTAYGVQGIALLAVVMTLMM
APGHLLLPILQCLVIVQSISLACALVCLYATLMSLSSPLQAGVDFTLFQCTDAAIAILAGVIGGVVAQHFGYAACFLFAG
AFTLLAAWVAYIRLHSARELMTSAID
>Mature_425_residues
SDVQSNVKPLTLTTGRVIFAIAGVYVTQSLVSALSMQSLPALVRAAGGSLALAGATTLFMLPWALKFIWAPWIERWRLPP
GSQERRSRMLILRGQVALAAILTIAAAIGWFGREGGFPDTQIVALFVLFMVAGTVASTIDIASDGFCVDQLTRTGYGWGN
SVQVGGSYLGMMCGGGVFLMLSAASGWPVAMLMMAVLIMALSLPLWRITEPTRTATIPHVPALGYALRRKQARLGLLLVL
MLNSGMRFVLPLLAPLLLDHGLSMSALGALFSGGNIAAGIAGTLAGGLLMKYTSPGRALLTAYGVQGIALLAVVMTLMMA
PGHLLLPILQCLVIVQSISLACALVCLYATLMSLSSPLQAGVDFTLFQCTDAAIAILAGVIGGVVAQHFGYAACFLFAGA
FTLLAAWVAYIRLHSARELMTSAID

Specific function: Probably Acts As A Permease In The Beta-Lactamase Induction System And In Peptidoglycan Recycling. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli AmpG and yeast YBR220c [H]

Homologues:

Organism=Escherichia coli, GI1786636, Length=375, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004752
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44779; Mature: 44648

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVQSNVKPLTLTTGRVIFAIAGVYVTQSLVSALSMQSLPALVRAAGGSLALAGATTLF
CCCCHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHH
MLPWALKFIWAPWIERWRLPPGSQERRSRMLILRGQVALAAILTIAAAIGWFGREGGFPD
HHHHHHHHHHHHHHHHCCCCCCCHHHHCCEEHEEHHHHHHHHHHHHHHHHHHCCCCCCCH
TQIVALFVLFMVAGTVASTIDIASDGFCVDQLTRTGYGWGNSVQVGGSYLGMMCGGGVFL
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCEEECHHHHHHHHCCCCEE
MLSAASGWPVAMLMMAVLIMALSLPLWRITEPTRTATIPHVPALGYALRRKQARLGLLLV
EEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LMLNSGMRFVLPLLAPLLLDHGLSMSALGALFSGGNIAAGIAGTLAGGLLMKYTSPGRAL
HHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCHHH
LTAYGVQGIALLAVVMTLMMAPGHLLLPILQCLVIVQSISLACALVCLYATLMSLSSPLQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AGVDFTLFQCTDAAIAILAGVIGGVVAQHFGYAACFLFAGAFTLLAAWVAYIRLHSAREL
HCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTSAID
HHHHCC
>Mature Secondary Structure 
SDVQSNVKPLTLTTGRVIFAIAGVYVTQSLVSALSMQSLPALVRAAGGSLALAGATTLF
CCCHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHH
MLPWALKFIWAPWIERWRLPPGSQERRSRMLILRGQVALAAILTIAAAIGWFGREGGFPD
HHHHHHHHHHHHHHHHCCCCCCCHHHHCCEEHEEHHHHHHHHHHHHHHHHHHCCCCCCCH
TQIVALFVLFMVAGTVASTIDIASDGFCVDQLTRTGYGWGNSVQVGGSYLGMMCGGGVFL
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCEEECHHHHHHHHCCCCEE
MLSAASGWPVAMLMMAVLIMALSLPLWRITEPTRTATIPHVPALGYALRRKQARLGLLLV
EEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LMLNSGMRFVLPLLAPLLLDHGLSMSALGALFSGGNIAAGIAGTLAGGLLMKYTSPGRAL
HHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCHHH
LTAYGVQGIALLAVVMTLMMAPGHLLLPILQCLVIVQSISLACALVCLYATLMSLSSPLQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AGVDFTLFQCTDAAIAILAGVIGGVVAQHFGYAACFLFAGAFTLLAAWVAYIRLHSAREL
HCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTSAID
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1956282; 7542800 [H]