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The map label for this gene is yoaE [H]

Identifier: 218928883

GI number: 218928883

Start: 2004523

End: 2005917

Strand: Direct

Name: yoaE [H]

Synonym: YPO1759

Alternate gene names: 218928883

Gene position: 2004523-2005917 (Clockwise)

Preceding gene: 218928877

Following gene: 218928885

Centisome position: 43.07

GC content: 51.97

Gene sequence:

>1395_bases
TTGTTCTGGGCATTGATCATGCGTTTGGGGCTGTTGTCGGTCATTTCATGGATGGTCACGCTTACGACACCGCTGTTCAG
CGTCGGTGCGTTTAATTTCGCTGGGCGAGATTTGATTTTGCTGGTGGGGGGGTTGTTCCTGCTGTTTAAAGCCACCACCG
AGCTACATGAACGGTTAGAAGGTAATCAGCACAATGATGGGGCGAACCGGGGCTATGCCAGCTTCTGGGCGGTCGTGGTC
CAAATTGTCATCCTGGATGCGGTCTTCTCCCTGGATGCAGTGATTACGGCGGTAGGGATGGTCAACGACTTGCCTATCAT
GATGACAGCCGTGGTGATTGCCATGGGGGTCATGTTACTGGCCTCGAAATCCCTGACCCGATTTGTGAACGAGCACCCAA
CGGTGGTCGTGCTATGTCTGAGCTTCCTGTTGATGATCGGCTTGAGTTTGATTGCCGAAGGTTTTGGCTTCCACATTCCG
AAAGGTTACCTGTATGCCGCGATTGGCTTCTCAATCTTGATTGAGTTGTTTAACCAGATTGCGCGTCGTAACTTCATCAA
ACATGAATCGCGTTTACCAAGACGTCAACGTACAGCAGAAGCGATCATCCGTCTGATGGGTGGGCGTCAGCAGCAGGAAC
AACAGAGTGGTGACCCTCAACAGGCAGTACCAACAGAAGCCTTTGCTGAAGAAGAACGCTATATGATCAGCGGGGTATTA
ACGCTGGCCTCGCGATCATTACGCAGCGTAATGACGCCGCGTACCGAAATTTCTTGGGTTGATTGCAACCGTTCACAAGC
CGAAATTCGCGAGCAGTTGTTAGATACCCCACACAGTTTGTTCCCTGTTTGCCGCGACTCTTTGGATCAAATCATTGGTG
TGGTTCGCGCTAAAGACCTGCTGGTGGCGATTGAGCGGGGTGAGTCTATTTGTGATTTTGCCGCGACAACCCCGCCAATC
GTGGTGCCTGATACCATGGATGTGATTAATCTGTTGGGGGTATTGCGCAAAGCCAAGGGCCGCCTGGTGGTGGTGAATGA
CGAGTTCGGCGTGGTGCAGGGTCTGGTAACACCGCTGGATGTCCTGGAAGCGATTGCCGGTGAATTCCCTGATGAAGATG
AAACGCCAGATATTATTGCCGATGGTGATGGTTGGTTGGTGAAAGGGGGGGCAGATCTGCACTCGTTGGAACAGGCGCTG
GATTGCCAGACACTGGTTAGCCCAACCGCTGATTATGCCTCGTTAGCCGGTTTACTGTTGTCTCATTCGGGCCATATGCC
AACGGCAGGGGATGTGATTGAGCTGCATAACCTGCGCTTCCAGATTATGGACGTCTCAGATTACCGTATTGAGCTGGTGC
GCATTACCAAGCTGAGTAATGAGTTGGAAGAGTAA

Upstream 100 bases:

>100_bases
CGCATCATCTGGATCATGTTCTTATTTTCGGAGTCTGACATGGAACTTTTAATGGACCCCTCAATTTGGGCAGGGTTGCT
TACACTGGTGGTATTAGAGA

Downstream 100 bases:

>100_bases
GCAGAGAGTGGAACCTCAGGGGCGCTTCGGCTCCCCTGAGGTTATTGACAACGTACCCGCGACGGAGGTAACAGACAGAA
CGCAAAGACGCCGTAAACCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MFWALIMRLGLLSVISWMVTLTTPLFSVGAFNFAGRDLILLVGGLFLLFKATTELHERLEGNQHNDGANRGYASFWAVVV
QIVILDAVFSLDAVITAVGMVNDLPIMMTAVVIAMGVMLLASKSLTRFVNEHPTVVVLCLSFLLMIGLSLIAEGFGFHIP
KGYLYAAIGFSILIELFNQIARRNFIKHESRLPRRQRTAEAIIRLMGGRQQQEQQSGDPQQAVPTEAFAEEERYMISGVL
TLASRSLRSVMTPRTEISWVDCNRSQAEIREQLLDTPHSLFPVCRDSLDQIIGVVRAKDLLVAIERGESICDFAATTPPI
VVPDTMDVINLLGVLRKAKGRLVVVNDEFGVVQGLVTPLDVLEAIAGEFPDEDETPDIIADGDGWLVKGGADLHSLEQAL
DCQTLVSPTADYASLAGLLLSHSGHMPTAGDVIELHNLRFQIMDVSDYRIELVRITKLSNELEE

Sequences:

>Translated_464_residues
MFWALIMRLGLLSVISWMVTLTTPLFSVGAFNFAGRDLILLVGGLFLLFKATTELHERLEGNQHNDGANRGYASFWAVVV
QIVILDAVFSLDAVITAVGMVNDLPIMMTAVVIAMGVMLLASKSLTRFVNEHPTVVVLCLSFLLMIGLSLIAEGFGFHIP
KGYLYAAIGFSILIELFNQIARRNFIKHESRLPRRQRTAEAIIRLMGGRQQQEQQSGDPQQAVPTEAFAEEERYMISGVL
TLASRSLRSVMTPRTEISWVDCNRSQAEIREQLLDTPHSLFPVCRDSLDQIIGVVRAKDLLVAIERGESICDFAATTPPI
VVPDTMDVINLLGVLRKAKGRLVVVNDEFGVVQGLVTPLDVLEAIAGEFPDEDETPDIIADGDGWLVKGGADLHSLEQAL
DCQTLVSPTADYASLAGLLLSHSGHMPTAGDVIELHNLRFQIMDVSDYRIELVRITKLSNELEE
>Mature_464_residues
MFWALIMRLGLLSVISWMVTLTTPLFSVGAFNFAGRDLILLVGGLFLLFKATTELHERLEGNQHNDGANRGYASFWAVVV
QIVILDAVFSLDAVITAVGMVNDLPIMMTAVVIAMGVMLLASKSLTRFVNEHPTVVVLCLSFLLMIGLSLIAEGFGFHIP
KGYLYAAIGFSILIELFNQIARRNFIKHESRLPRRQRTAEAIIRLMGGRQQQEQQSGDPQQAVPTEAFAEEERYMISGVL
TLASRSLRSVMTPRTEISWVDCNRSQAEIREQLLDTPHSLFPVCRDSLDQIIGVVRAKDLLVAIERGESICDFAATTPPI
VVPDTMDVINLLGVLRKAKGRLVVVNDEFGVVQGLVTPLDVLEAIAGEFPDEDETPDIIADGDGWLVKGGADLHSLEQAL
DCQTLVSPTADYASLAGLLLSHSGHMPTAGDVIELHNLRFQIMDVSDYRIELVRITKLSNELEE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Escherichia coli, GI1788119, Length=457, Percent_Identity=71.5536105032823, Blast_Score=650, Evalue=0.0,
Organism=Escherichia coli, GI87082033, Length=464, Percent_Identity=45.9051724137931, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI1789197, Length=181, Percent_Identity=50.2762430939227, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790664, Length=235, Percent_Identity=26.3829787234043, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1786879, Length=226, Percent_Identity=29.2035398230088, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI145693175, Length=231, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005496
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF03741 TerC [H]

EC number: NA

Molecular weight: Translated: 51096; Mature: 51096

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCCCCCCCHHHHCCCEEEEEECCCCEEEEHHHHHHHHHHCC
>Mature Secondary Structure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HCCCCCCCCCCHHHHCCCEEEEEECCCCEEEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]