Click here to switch to the map view.

The map label for this gene is lolC [H]

Identifier: 218928762

GI number: 218928762

Start: 1850489

End: 1851691

Strand: Direct

Name: lolC [H]

Synonym: YPO1626

Alternate gene names: 218928762

Gene position: 1850489-1851691 (Clockwise)

Preceding gene: 218928760

Following gene: 218928763

Centisome position: 39.76

GC content: 52.04

Gene sequence:

>1203_bases
ATGTATCAACCTGTCGCCCTATTTATCGGCCTGCGTTATATGCGTGGGCGTGCTTCTGACCGCTTCGGTCGGTTTGTTTC
GTGGCTTTCTACCATTGGCATTACGCTGGGGGTGATGGCTCTTATCACGGTATTGTCTGTGATGAATGGTTTTGAGCGTA
ATCTGCAAGATACGATTTTGGGGCTTATGCCACAGGCGCTGATTACCACACCACAAGGTTCTTTGGATCCAAACAAGATA
CCGGCTTCAACCCTAAAATCGCTGAGCGGTGTCAGTGATATTGTGCCGTTGACCACGGCGGATGTGGTGTTACAAAGTGC
GCGTAATTTGGCCGCCGGTGTGATGCTGGGGGTTGATCCACAGCAGCATGAACCATTGGCCAATTATTTGGTTAACGTGG
ATATAAAAGCGTTAGCGCCAGGTAGCTACAACATCATCCTCGGCGAGAAGTTAGCGGGCCAGCTCGGGGTTAAACGCGGT
GAAACACTGCGTTTGATGGTACCGAGTGCCAGCCAATTCACGCCAATGGGCCGTATTCCCAGCCAGCGTGTGTTTAATAT
TATCGGCACCTTTGCAGCGAATAGCGAAGTTGATGGCTATCAAATTTTGGTTAACCAGCAGGATGCATCACGCCTGATGC
GTTACCCTCTTGGGAATATTACCGGCTGGCGCTTATTCCTCTCGCAGCCGCTGTCGGTCGATAGCCTGAGCCAGCAGAGT
TTGCCAGAAGGCACCGTATGGAAAGACTGGCGTGACCGTAAAGGTGAGCTTTTCCAGGCCGTGCGGATGGAAAAGAACAT
GATGGGGTTATTGCTCAGTCTGATTATTGCTGTCGCAGCCTTTAATATCATTACGTCACTGGGGCTGTTAGTGATGGAAA
AACAAGGCGAGGTGGCGATTTTGCAGACTCAAGGGTTGAGTCGCCGGCAAATTATGTTGGTGTTTATGGTGCAAGGTGCC
ACCGCTGGGGTTATCGGCGCATTGCTAGGGGCAGGGCTGGGGGTTTTACTCGCCAGCCAATTGAACACCCTGATCCCTAT
TTTGGGCGTATTGATTGATGGCGCAACGCTACCCGTGGAGATTGACCCACTTCAGGTTACGGTCATTGCACTGCTAGCCA
TGGTGATCGCTCTGTTGTCCACGCTGTACCCTTCTTGGCGCGCCGCCGCCGCACAACCCGCAGAGGCTTTACGCTATGAG
TAA

Upstream 100 bases:

>100_bases
TAAAAGCCGGAGATATAGACGGTTAATGGTTCCATAAAGCGGGAGTACCCTTTATTATCCTCGATCACTTTGTTTTAGCA
ACAGGATCTAAACAGATTTC

Downstream 100 bases:

>100_bases
TCATCCTTTATTACAATGTATAAACCTGTGCAAGCGTTATCAGGAAGGCCAACTGCATACTGATGTCCTGCGCAATGTCT
CTTTCGCTATCGAGCCTGGT

Product: outer membrane-specific lipoprotein transporter subunit LolC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MYQPVALFIGLRYMRGRASDRFGRFVSWLSTIGITLGVMALITVLSVMNGFERNLQDTILGLMPQALITTPQGSLDPNKI
PASTLKSLSGVSDIVPLTTADVVLQSARNLAAGVMLGVDPQQHEPLANYLVNVDIKALAPGSYNIILGEKLAGQLGVKRG
ETLRLMVPSASQFTPMGRIPSQRVFNIIGTFAANSEVDGYQILVNQQDASRLMRYPLGNITGWRLFLSQPLSVDSLSQQS
LPEGTVWKDWRDRKGELFQAVRMEKNMMGLLLSLIIAVAAFNIITSLGLLVMEKQGEVAILQTQGLSRRQIMLVFMVQGA
TAGVIGALLGAGLGVLLASQLNTLIPILGVLIDGATLPVEIDPLQVTVIALLAMVIALLSTLYPSWRAAAAQPAEALRYE

Sequences:

>Translated_400_residues
MYQPVALFIGLRYMRGRASDRFGRFVSWLSTIGITLGVMALITVLSVMNGFERNLQDTILGLMPQALITTPQGSLDPNKI
PASTLKSLSGVSDIVPLTTADVVLQSARNLAAGVMLGVDPQQHEPLANYLVNVDIKALAPGSYNIILGEKLAGQLGVKRG
ETLRLMVPSASQFTPMGRIPSQRVFNIIGTFAANSEVDGYQILVNQQDASRLMRYPLGNITGWRLFLSQPLSVDSLSQQS
LPEGTVWKDWRDRKGELFQAVRMEKNMMGLLLSLIIAVAAFNIITSLGLLVMEKQGEVAILQTQGLSRRQIMLVFMVQGA
TAGVIGALLGAGLGVLLASQLNTLIPILGVLIDGATLPVEIDPLQVTVIALLAMVIALLSTLYPSWRAAAAQPAEALRYE
>Mature_400_residues
MYQPVALFIGLRYMRGRASDRFGRFVSWLSTIGITLGVMALITVLSVMNGFERNLQDTILGLMPQALITTPQGSLDPNKI
PASTLKSLSGVSDIVPLTTADVVLQSARNLAAGVMLGVDPQQHEPLANYLVNVDIKALAPGSYNIILGEKLAGQLGVKRG
ETLRLMVPSASQFTPMGRIPSQRVFNIIGTFAANSEVDGYQILVNQQDASRLMRYPLGNITGWRLFLSQPLSVDSLSQQS
LPEGTVWKDWRDRKGELFQAVRMEKNMMGLLLSLIIAVAAFNIITSLGLLVMEKQGEVAILQTQGLSRRQIMLVFMVQGA
TAGVIGALLGAGLGVLLASQLNTLIPILGVLIDGATLPVEIDPLQVTVIALLAMVIALLSTLYPSWRAAAAQPAEALRYE

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=400, Percent_Identity=78.5, Blast_Score=614, Evalue=1e-177,
Organism=Escherichia coli, GI1787362, Length=423, Percent_Identity=29.3144208037825, Blast_Score=140, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43134; Mature: 43134

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQPVALFIGLRYMRGRASDRFGRFVSWLSTIGITLGVMALITVLSVMNGFERNLQDTIL
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLMPQALITTPQGSLDPNKIPASTLKSLSGVSDIVPLTTADVVLQSARNLAAGVMLGVDP
HHCCHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
QQHEPLANYLVNVDIKALAPGSYNIILGEKLAGQLGVKRGETLRLMVPSASQFTPMGRIP
HHCCCHHHHHEECEEEEECCCCEEEEECHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCC
SQRVFNIIGTFAANSEVDGYQILVNQQDASRLMRYPLGNITGWRLFLSQPLSVDSLSQQS
HHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCHHC
LPEGTVWKDWRDRKGELFQAVRMEKNMMGLLLSLIIAVAAFNIITSLGLLVMEKQGEVAI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEE
LQTQGLSRRQIMLVFMVQGATAGVIGALLGAGLGVLLASQLNTLIPILGVLIDGATLPVE
EECCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
IDPLQVTVIALLAMVIALLSTLYPSWRAAAAQPAEALRYE
ECHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHCCC
>Mature Secondary Structure
MYQPVALFIGLRYMRGRASDRFGRFVSWLSTIGITLGVMALITVLSVMNGFERNLQDTIL
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLMPQALITTPQGSLDPNKIPASTLKSLSGVSDIVPLTTADVVLQSARNLAAGVMLGVDP
HHCCHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
QQHEPLANYLVNVDIKALAPGSYNIILGEKLAGQLGVKRGETLRLMVPSASQFTPMGRIP
HHCCCHHHHHEECEEEEECCCCEEEEECHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCC
SQRVFNIIGTFAANSEVDGYQILVNQQDASRLMRYPLGNITGWRLFLSQPLSVDSLSQQS
HHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCHHC
LPEGTVWKDWRDRKGELFQAVRMEKNMMGLLLSLIIAVAAFNIITSLGLLVMEKQGEVAI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEE
LQTQGLSRRQIMLVFMVQGATAGVIGALLGAGLGVLLASQLNTLIPILGVLIDGATLPVE
EECCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
IDPLQVTVIALLAMVIALLSTLYPSWRAAAAQPAEALRYE
ECHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]