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The map label for this gene is mukE

Identifier: 218928552

GI number: 218928552

Start: 1587825

End: 1588526

Strand: Direct

Name: mukE

Synonym: YPO1404

Alternate gene names: 218928552

Gene position: 1587825-1588526 (Clockwise)

Preceding gene: 218928551

Following gene: 218928553

Centisome position: 34.12

GC content: 47.86

Gene sequence:

>702_bases
ATGCCCGTTAAGCTGGCTCAGGCATTAGCCAACACATTATTTCCGGCATTAGACAGCCAGTTACGTGCTGGCCGTCATAT
TGGTATTGATGAGTTGGATAATCATGCTTTTTTGATGGATTTTCAGGAGCAACTGGAAGAATTTTACGCTCGCTATAATG
TCGAGTTAATCCGTGCGCCGGAAGGTTTCTTCTATTTGCGTCCTCGTTCAACCACGCTTATTCCGCGCTCAGTTTTATCT
GAGTTGGATATGATGGTCGGCAAAATTCTCTGTTATCTCTACCTCAGCCCGGAACGGCTGGCTCATGAAGGTATCTTCTC
TCAGCAAGAGCTGTACGAAGAGTTACTGAGCCTGGCCGATGAGAGCAAATTGCTGAAGTTTGTTAACCAGCGCTCGACCG
GGTCTGATTTGGATAAACAGAAGTTACAGGAAAAAGTCCGGACGTCACTTAACCGGCTGCGTCGGTTGGGCATGATTTAT
TTTATGGGCAACGACAGCACCAAGTTTCGCATCACTGAAGCGGTATTCCGTTTTGGTGCGGATGTACGCAGCGGTGATGA
TCAACGTGAAGCCCAGCTACGCATGATCCGTGATGGCGAAGCCATGGCGGTAGAAAATAGTCTGTCACTTCATGATGAAA
GTGATGATGCTGATGTCACCATGGGCAATGCAGCGGACAGTGTAGAGGATGAACAGGAATGA

Upstream 100 bases:

>100_bases
GCCGAAGCCGATTTCTCAGGGTTGCCAGCCGAATGGTTAGCAATCAATGATTACGGAGCCAAGGTGCAGGCACATGTCAT
CAACAAATATTGAAGTAGTA

Downstream 100 bases:

>100_bases
TTGAACGCGGTAAATTTCGCTCACTGACCTTGGTTAACTGGAATGGTTTCTTTGCCCGAACATTCGATCTTGATGAGCTG
GTAACAACCCTCTCCGGCGG

Product: condesin subunit E

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MPVKLAQALANTLFPALDSQLRAGRHIGIDELDNHAFLMDFQEQLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLS
ELDMMVGKILCYLYLSPERLAHEGIFSQQELYEELLSLADESKLLKFVNQRSTGSDLDKQKLQEKVRTSLNRLRRLGMIY
FMGNDSTKFRITEAVFRFGADVRSGDDQREAQLRMIRDGEAMAVENSLSLHDESDDADVTMGNAADSVEDEQE

Sequences:

>Translated_233_residues
MPVKLAQALANTLFPALDSQLRAGRHIGIDELDNHAFLMDFQEQLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLS
ELDMMVGKILCYLYLSPERLAHEGIFSQQELYEELLSLADESKLLKFVNQRSTGSDLDKQKLQEKVRTSLNRLRRLGMIY
FMGNDSTKFRITEAVFRFGADVRSGDDQREAQLRMIRDGEAMAVENSLSLHDESDDADVTMGNAADSVEDEQE
>Mature_232_residues
PVKLAQALANTLFPALDSQLRAGRHIGIDELDNHAFLMDFQEQLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLSE
LDMMVGKILCYLYLSPERLAHEGIFSQQELYEELLSLADESKLLKFVNQRSTGSDLDKQKLQEKVRTSLNRLRRLGMIYF
MGNDSTKFRITEAVFRFGADVRSGDDQREAQLRMIRDGEAMAVENSLSLHDESDDADVTMGNAADSVEDEQE

Specific function: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interactio

COG id: COG3095

COG function: function code D; Uncharacterized protein involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm, nucleoid. Note=Restricted to the nucleoid region (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mukE family

Homologues:

Organism=Escherichia coli, GI226510932, Length=231, Percent_Identity=81.8181818181818, Blast_Score=390, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MUKE_YERPE (Q8D049)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AF0171
- RefSeq:   NP_670067.1
- RefSeq:   NP_992555.1
- RefSeq:   YP_002346427.1
- ProteinModelPortal:   Q8D049
- GeneID:   1147713
- GeneID:   1174245
- GeneID:   2766263
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO1404
- KEGG:   ypk:y2766
- KEGG:   ypm:YP_1189
- HOGENOM:   HBG296837
- OMA:   GKVLCYL
- ProtClustDB:   PRK05256
- BioCyc:   YPES187410:Y2766-MONOMER
- BioCyc:   YPES214092:YPO1404-MONOMER
- GO:   GO:0005737
- GO:   GO:0009295
- HAMAP:   MF_01802
- InterPro:   IPR007385

Pfam domain/function: PF04288 MukE

EC number: NA

Molecular weight: Translated: 26683; Mature: 26551

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVKLAQALANTLFPALDSQLRAGRHIGIDELDNHAFLMDFQEQLEEFYARYNVELIRAP
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHCEEEEECC
EGFFYLRPRSTTLIPRSVLSELDMMVGKILCYLYLSPERLAHEGIFSQQELYEELLSLAD
CCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHC
ESKLLKFVNQRSTGSDLDKQKLQEKVRTSLNRLRRLGMIYFMGNDSTKFRITEAVFRFGA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCC
DVRSGDDQREAQLRMIRDGEAMAVENSLSLHDESDDADVTMGNAADSVEDEQE
CCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCC
>Mature Secondary Structure 
PVKLAQALANTLFPALDSQLRAGRHIGIDELDNHAFLMDFQEQLEEFYARYNVELIRAP
CHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHCEEEEECC
EGFFYLRPRSTTLIPRSVLSELDMMVGKILCYLYLSPERLAHEGIFSQQELYEELLSLAD
CCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHC
ESKLLKFVNQRSTGSDLDKQKLQEKVRTSLNRLRRLGMIYFMGNDSTKFRITEAVFRFGA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCC
DVRSGDDQREAQLRMIRDGEAMAVENSLSLHDESDDADVTMGNAADSVEDEQE
CCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430