Click here to switch to the map view.

The map label for this gene is fepD [C]

Identifier: 218928492

GI number: 218928492

Start: 1508555

End: 1509460

Strand: Direct

Name: fepD [C]

Synonym: YPO1344

Alternate gene names: 218928492

Gene position: 1508555-1509460 (Clockwise)

Preceding gene: 218928491

Following gene: 218928493

Centisome position: 32.42

GC content: 51.55

Gene sequence:

>906_bases
TTGATGTATTGCGACTGTTTCTGGTGGATTCTTCGCAGCATGATGAACTACACCAGATCATTTTTGGTCCATTCGTTTGC
CGATGACGTTAACCGCCGTGGTGGTGGGCGCGAGTTTGGGTTTGGCTGGCTTGTTGATGCAAACCGTACTGGCGAATCCG
TTAGCCAGTCCTTATACCTTGGGGATTTCAGCCGCGGCAGGATTTGGTGCCGCATTATCGATCATCACTGGCTTCAGCGT
GGGGGGAGTCTTGTCATTAGGCACCCCATTATTGGCTTCACTGATGGCATTACTGGCCTGCCTGCCCATTTACTTTCTGG
GCCAACGGCAGGGGATGACACCGCAAATTCTGGTGTTGAGCGGCATTGTGGTGCTGTTCTTCTTCCAGTCGTTGCAATCA
CTCATGTTATTTCGGCCTCACCAGAAGCGATGCAACAAATTGTATTCTGGCTGTTTGGCAGCCTGCTAAAAGCCAATATG
CAGGGGGTGCTAATGACGGGCAGCGTACTGGCTTGTTCACTGGTTATCTGTTTGCAGCAGGCATGGCGATTGACCGCGCT
TTCAGCGGGGGAGGAGCAAGCGCTAGGTTTGGGGATTAACGTAAGCGCCTTACGTAAGTTAGCGTTTCTTCTGGCGACCT
TGTTGACCGCCGCCTCTGTGTCTTTTGTCGGCACTATCGGCTTTATCGGTTTGGTCGCCCCTCACTTCGCCCGTATGTTG
GTCGGCGAAGATCAACGCTATCTGATCGGTATTTCGGCACTTTGTGGCAGCCTGCTATTGGTTCTGGCCTCTATCATTTC
CAAACTCATACTGCCAAATGGTGTCGTGCCGATCGGCATTATTATTGCGCTGATCGGTGTCCCGGTATTGTTCTATTTTG
TGACTAAACAGGTGAAACGGGCATGA

Upstream 100 bases:

>100_bases
CTTCATCTACGACGCGGGTTATTCACACTGGCATTGATCGGCTCGCTACTGGCCGCTATGGTCATCGATCTGGCCACTGG
CGCGGCCAACCTTAGCCCAC

Downstream 100 bases:

>100_bases
CGCAACTGACGTTAAAGCACGTCGGCGTCACGCTTCATAAACGCCCACTGCTCACCGATATTTCTCTAACGTGGCCTGCG
GCACAGGTGAGCGGCATTAT

Product: FecCD transport family protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MMYCDCFWWILRSMMNYTRSFLVHSFADDVNRRGGGREFGFGWLVDANRTGESVSQSLYLGDFSRGRIWCRIIDHHWLQR
GGSLVIRHPIIGFTDGITGLPAHLLSGPTAGDDTANSGVERHCGAVLLPVVAITHVISASPEAMQQIVFWLFGSLLKANM
QGVLMTGSVLACSLVICLQQAWRLTALSAGEEQALGLGINVSALRKLAFLLATLLTAASVSFVGTIGFIGLVAPHFARML
VGEDQRYLIGISALCGSLLLVLASIISKLILPNGVVPIGIIIALIGVPVLFYFVTKQVKRA

Sequences:

>Translated_301_residues
MMYCDCFWWILRSMMNYTRSFLVHSFADDVNRRGGGREFGFGWLVDANRTGESVSQSLYLGDFSRGRIWCRIIDHHWLQR
GGSLVIRHPIIGFTDGITGLPAHLLSGPTAGDDTANSGVERHCGAVLLPVVAITHVISASPEAMQQIVFWLFGSLLKANM
QGVLMTGSVLACSLVICLQQAWRLTALSAGEEQALGLGINVSALRKLAFLLATLLTAASVSFVGTIGFIGLVAPHFARML
VGEDQRYLIGISALCGSLLLVLASIISKLILPNGVVPIGIIIALIGVPVLFYFVTKQVKRA
>Mature_301_residues
MMYCDCFWWILRSMMNYTRSFLVHSFADDVNRRGGGREFGFGWLVDANRTGESVSQSLYLGDFSRGRIWCRIIDHHWLQR
GGSLVIRHPIIGFTDGITGLPAHLLSGPTAGDDTANSGVERHCGAVLLPVVAITHVISASPEAMQQIVFWLFGSLLKANM
QGVLMTGSVLACSLVICLQQAWRLTALSAGEEQALGLGINVSALRKLAFLLATLLTAASVSFVGTIGFIGLVAPHFARML
VGEDQRYLIGISALCGSLLLVLASIISKLILPNGVVPIGIIIALIGVPVLFYFVTKQVKRA

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=162, Percent_Identity=33.9506172839506, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790741, Length=151, Percent_Identity=34.4370860927152, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790740, Length=211, Percent_Identity=30.8056872037915, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786347, Length=163, Percent_Identity=36.1963190184049, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 32556; Mature: 32556

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMYCDCFWWILRSMMNYTRSFLVHSFADDVNRRGGGREFGFGWLVDANRTGESVSQSLYL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHC
GDFSRGRIWCRIIDHHWLQRGGSLVIRHPIIGFTDGITGLPAHLLSGPTAGDDTANSGVE
CCCCCCEEEEEHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHH
RHCGAVLLPVVAITHVISASPEAMQQIVFWLFGSLLKANMQGVLMTGSVLACSLVICLQQ
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHH
AWRLTALSAGEEQALGLGINVSALRKLAFLLATLLTAASVSFVGTIGFIGLVAPHFARML
HHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGEDQRYLIGISALCGSLLLVLASIISKLILPNGVVPIGIIIALIGVPVLFYFVTKQVKR
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
A
C
>Mature Secondary Structure
MMYCDCFWWILRSMMNYTRSFLVHSFADDVNRRGGGREFGFGWLVDANRTGESVSQSLYL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHC
GDFSRGRIWCRIIDHHWLQRGGSLVIRHPIIGFTDGITGLPAHLLSGPTAGDDTANSGVE
CCCCCCEEEEEHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHH
RHCGAVLLPVVAITHVISASPEAMQQIVFWLFGSLLKANMQGVLMTGSVLACSLVICLQQ
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHH
AWRLTALSAGEEQALGLGINVSALRKLAFLLATLLTAASVSFVGTIGFIGLVAPHFARML
HHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGEDQRYLIGISALCGSLLLVLASIISKLILPNGVVPIGIIIALIGVPVLFYFVTKQVKR
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]