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The map label for this gene is uxuA [H]

Identifier: 218928434

GI number: 218928434

Start: 1441211

End: 1442404

Strand: Direct

Name: uxuA [H]

Synonym: YPO1283

Alternate gene names: 218928434

Gene position: 1441211-1442404 (Clockwise)

Preceding gene: 218928432

Following gene: 218928437

Centisome position: 30.97

GC content: 49.83

Gene sequence:

>1194_bases
ATGGAACAAACATGGCGTTGGTATGGCCCGAATGATCCGGTGTCGTTAGATGATATCCGTCAAGCGGGTGCTACCGGAGT
AGTCACGGCGTTACACCATATCCCGAATGGTGTTGTGTGGCCAGTCAGTGAGATCAAGCAGCGTCAGGCCGAATTAGCAG
CTAAAAACCTGGTATGGTCTGTTGTGGAAAGTGTGCCTATTCATGAGGACATCAAAACTCATAGCGGTAACTATCAGCAA
TACATTGAAAATTACCAACAAACACTGCGTAACATTGCAGAATGCGGTATTGACACCGTGTGCTACAACTTCATGCCGAT
ACTGGACTGGACGCGTACTGATCTGGAATATGAATTACCAGACGGTTCTAAAGCGTTGCGTTTTGACCAGATAGCTTTTG
CCGCTTTTGAGCTGCATATTCTAAAACGCCCTGGTGCCAGCAATGACTATACGGCGGAAGAACAAGTACAGGCAGAAGCG
TATTTCAACGCGATGACTGAAGCTGATATTGCCAAGCTGACGGGCAATATTATTGCAGGTCTGCCAGGGGCTGAAGAGGG
CTATACGCTGGATCAGTTCCGTGCTCGGTTGGCTGAGTACGATGGGATTGATAAAGCGCAACTGCGTGAGAACATGGCTT
ACTTCCTGCGCGCTATCATTCCGGTGGCAGAACAAGTGGGCTTGCGTATGGCGGTGCACCCAGATGATCCACCGCGCCCA
ATCCTTGGCCTACCGCGTATCGTTTCAACCATTGAAGATATGCAGTGGCTGAAAGAGACGGTGGATAGCATTCACAACGG
TTTCACCATGTGTACCGGTTCGTATGGTGTGCGTGCTGATAACGATTTGGTGAAGATGATCGAAACCTTTGGCGATCGTA
TTCACTTCACGCATTTGCGTTCCACCTGTCGTGAAGGAAATCCAAAAACCTTCCATGAAGGGGGGCATTTGCAAGGCGAT
GTGGATATGTACTCGGTGGTAAAAGCCATTTTAACCGAAGAACAGCGCCGCCAGTCACTGGGGGATATGCGTCCAATACC
TATGCGTCCGGACCATGGTCATCAGATGCTGGACGATTTGCACAAGAAAACCAATCCGGGCTACTCGGCAATTGGGCGTC
TGAAAGGGCTGGCAGAAGTTCGTGGTGTGGAATTGGCACTGAAACGGACATTTTTCCCCGAGCTGAAGCAGTAG

Upstream 100 bases:

>100_bases
CCGTTATCGGCAGAAAAGTCCGTTATCGGCAGAAAAAGGCGGCTTTAACCGTTAGCGGGTTAATTTTATTATTGTTGCGT
ATGCAGAAGGTAAAAATAAA

Downstream 100 bases:

>100_bases
TTTTGCACGATCAGTGAAGAGATAACCGTTAAGGGCCGGTTTCCGGCTCTTAACGTAGAGAGACCCAATAGATTCAAGTT
GCAGAAGGGCGGCCAGCAAG

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MEQTWRWYGPNDPVSLDDIRQAGATGVVTALHHIPNGVVWPVSEIKQRQAELAAKNLVWSVVESVPIHEDIKTHSGNYQQ
YIENYQQTLRNIAECGIDTVCYNFMPILDWTRTDLEYELPDGSKALRFDQIAFAAFELHILKRPGASNDYTAEEQVQAEA
YFNAMTEADIAKLTGNIIAGLPGAEEGYTLDQFRARLAEYDGIDKAQLRENMAYFLRAIIPVAEQVGLRMAVHPDDPPRP
ILGLPRIVSTIEDMQWLKETVDSIHNGFTMCTGSYGVRADNDLVKMIETFGDRIHFTHLRSTCREGNPKTFHEGGHLQGD
VDMYSVVKAILTEEQRRQSLGDMRPIPMRPDHGHQMLDDLHKKTNPGYSAIGRLKGLAEVRGVELALKRTFFPELKQ

Sequences:

>Translated_397_residues
MEQTWRWYGPNDPVSLDDIRQAGATGVVTALHHIPNGVVWPVSEIKQRQAELAAKNLVWSVVESVPIHEDIKTHSGNYQQ
YIENYQQTLRNIAECGIDTVCYNFMPILDWTRTDLEYELPDGSKALRFDQIAFAAFELHILKRPGASNDYTAEEQVQAEA
YFNAMTEADIAKLTGNIIAGLPGAEEGYTLDQFRARLAEYDGIDKAQLRENMAYFLRAIIPVAEQVGLRMAVHPDDPPRP
ILGLPRIVSTIEDMQWLKETVDSIHNGFTMCTGSYGVRADNDLVKMIETFGDRIHFTHLRSTCREGNPKTFHEGGHLQGD
VDMYSVVKAILTEEQRRQSLGDMRPIPMRPDHGHQMLDDLHKKTNPGYSAIGRLKGLAEVRGVELALKRTFFPELKQ
>Mature_397_residues
MEQTWRWYGPNDPVSLDDIRQAGATGVVTALHHIPNGVVWPVSEIKQRQAELAAKNLVWSVVESVPIHEDIKTHSGNYQQ
YIENYQQTLRNIAECGIDTVCYNFMPILDWTRTDLEYELPDGSKALRFDQIAFAAFELHILKRPGASNDYTAEEQVQAEA
YFNAMTEADIAKLTGNIIAGLPGAEEGYTLDQFRARLAEYDGIDKAQLRENMAYFLRAIIPVAEQVGLRMAVHPDDPPRP
ILGLPRIVSTIEDMQWLKETVDSIHNGFTMCTGSYGVRADNDLVKMIETFGDRIHFTHLRSTCREGNPKTFHEGGHLQGD
VDMYSVVKAILTEEQRRQSLGDMRPIPMRPDHGHQMLDDLHKKTNPGYSAIGRLKGLAEVRGVELALKRTFFPELKQ

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1790778, Length=392, Percent_Identity=78.5714285714286, Blast_Score=648, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004628
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03786 UxuA [H]

EC number: =4.2.1.8 [H]

Molecular weight: Translated: 44890; Mature: 44890

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQTWRWYGPNDPVSLDDIRQAGATGVVTALHHIPNGVVWPVSEIKQRQAELAAKNLVWS
CCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHH
VVESVPIHEDIKTHSGNYQQYIENYQQTLRNIAECGIDTVCYNFMPILDWTRTDLEYELP
HHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEECC
DGSKALRFDQIAFAAFELHILKRPGASNDYTAEEQVQAEAYFNAMTEADIAKLTGNIIAG
CCCCHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCC
LPGAEEGYTLDQFRARLAEYDGIDKAQLRENMAYFLRAIIPVAEQVGLRMAVHPDDPPRP
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
ILGLPRIVSTIEDMQWLKETVDSIHNGFTMCTGSYGVRADNDLVKMIETFGDRIHFTHLR
CCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHCCCEEHHHHH
STCREGNPKTFHEGGHLQGDVDMYSVVKAILTEEQRRQSLGDMRPIPMRPDHGHQMLDDL
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
HKKTNPGYSAIGRLKGLAEVRGVELALKRTFFPELKQ
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEQTWRWYGPNDPVSLDDIRQAGATGVVTALHHIPNGVVWPVSEIKQRQAELAAKNLVWS
CCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHH
VVESVPIHEDIKTHSGNYQQYIENYQQTLRNIAECGIDTVCYNFMPILDWTRTDLEYELP
HHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEECC
DGSKALRFDQIAFAAFELHILKRPGASNDYTAEEQVQAEAYFNAMTEADIAKLTGNIIAG
CCCCHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCC
LPGAEEGYTLDQFRARLAEYDGIDKAQLRENMAYFLRAIIPVAEQVGLRMAVHPDDPPRP
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
ILGLPRIVSTIEDMQWLKETVDSIHNGFTMCTGSYGVRADNDLVKMIETFGDRIHFTHLR
CCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHCCCEEHHHHH
STCREGNPKTFHEGGHLQGDVDMYSVVKAILTEEQRRQSLGDMRPIPMRPDHGHQMLDDL
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
HKKTNPGYSAIGRLKGLAEVRGVELALKRTFFPELKQ
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA