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The map label for this gene is uxuR [H]

Identifier: 218928432

GI number: 218928432

Start: 1438210

End: 1439010

Strand: Direct

Name: uxuR [H]

Synonym: YPO1279

Alternate gene names: 218928432

Gene position: 1438210-1439010 (Clockwise)

Preceding gene: 218928431

Following gene: 218928434

Centisome position: 30.9

GC content: 49.31

Gene sequence:

>801_bases
TTGGTCAGATCAATTTGGTATTTTCTACGCCAATGTCTGATGCAGGAAATTAAGGTTATGCGGTTATATCAGGAAGTGGG
CAGCCAACTGCGGGAAGCGATTGTCAGTGGGCGATACTCAGTGGGCGATCGTTTACCACCGGAGCGTGATATTGCCGAAA
ATTTCAGTGTCAGCCGTAGTGTGGTGCGTGAAGCCCTGATTATGCTCGAGCTGGAGAAGCTGGTAGAAGTACGCAAAGGC
TCCGGTGTTTACGTGGTGAATGTGCCCACGATGTCGCTTAATGGTGAGTCGGCTACGTCAATCGATAGTGGCTACGGCCC
GTTTGAACTGCTACAAGCCCGGCAATTGTTAGAGAGCGAAGTCGCGGCTTTTGCCGCAATGCAAGCCACCAAAGCCGATA
TCATTAAAATGCGTAATGCTATTGAGCAGGGAAAAGCCGCACTGACGGCTGGCGCGATAGATGAAAGCGCTGATGAGTTG
TTTCATTGTTTGTTAGCGCAATCGACACAAAATAGTGTGCTGGCCAATATGGTTGCGCAGACCTGGCAAGTCCGGAAAAG
TAGTGCAATGTGGCAGGGGGCGCATAGTCATACCGCCGATTTTAGCTACCGTTGGCAATGGTTGGATGATCACCAAAAAA
TCTTGCAAGCCGTGCTTCGCCGCGACAGTAAAGCCGCTAAGCAGGCCATGTGGCAGCATTTGGAGAATGTAAAATTGAAG
TTGCTGGAGATCTCTGATGCTGACCATCCAGATTTTGATGGCTACTTATTTGAGTCTGCGCCATATCAGATTGAAGAGTA
A

Upstream 100 bases:

>100_bases
AACATGTTTGGGCATCACGGTTTATCGACGTGATAAACCGTGATTTATCACCTGAAGTTGTTTGACCACATGATATACTC
GACGCCATTCATACACCCTT

Downstream 100 bases:

>100_bases
AAGATAACGTAAAAACCAACCGTAGTCGCACCAAGAGTACTAACGTCAACAGAACTAATATCAACAGAACTAATATCAAC
AGAACTAAACGCCAACAATA

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MVRSIWYFLRQCLMQEIKVMRLYQEVGSQLREAIVSGRYSVGDRLPPERDIAENFSVSRSVVREALIMLELEKLVEVRKG
SGVYVVNVPTMSLNGESATSIDSGYGPFELLQARQLLESEVAAFAAMQATKADIIKMRNAIEQGKAALTAGAIDESADEL
FHCLLAQSTQNSVLANMVAQTWQVRKSSAMWQGAHSHTADFSYRWQWLDDHQKILQAVLRRDSKAAKQAMWQHLENVKLK
LLEISDADHPDFDGYLFESAPYQIEE

Sequences:

>Translated_266_residues
MVRSIWYFLRQCLMQEIKVMRLYQEVGSQLREAIVSGRYSVGDRLPPERDIAENFSVSRSVVREALIMLELEKLVEVRKG
SGVYVVNVPTMSLNGESATSIDSGYGPFELLQARQLLESEVAAFAAMQATKADIIKMRNAIEQGKAALTAGAIDESADEL
FHCLLAQSTQNSVLANMVAQTWQVRKSSAMWQGAHSHTADFSYRWQWLDDHQKILQAVLRRDSKAAKQAMWQHLENVKLK
LLEISDADHPDFDGYLFESAPYQIEE
>Mature_266_residues
MVRSIWYFLRQCLMQEIKVMRLYQEVGSQLREAIVSGRYSVGDRLPPERDIAENFSVSRSVVREALIMLELEKLVEVRKG
SGVYVVNVPTMSLNGESATSIDSGYGPFELLQARQLLESEVAAFAAMQATKADIIKMRNAIEQGKAALTAGAIDESADEL
FHCLLAQSTQNSVLANMVAQTWQVRKSSAMWQGAHSHTADFSYRWQWLDDHQKILQAVLRRDSKAAKQAMWQHLENVKLK
LLEISDADHPDFDGYLFESAPYQIEE

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=243, Percent_Identity=51.8518518518518, Blast_Score=254, Evalue=5e-69,
Organism=Escherichia coli, GI87082208, Length=243, Percent_Identity=48.1481481481481, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1790032, Length=229, Percent_Identity=29.2576419213974, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI48994955, Length=237, Percent_Identity=25.3164556962025, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789353, Length=240, Percent_Identity=27.5, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786303, Length=166, Percent_Identity=27.710843373494, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789621, Length=226, Percent_Identity=28.3185840707965, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 30101; Mature: 30101

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRSIWYFLRQCLMQEIKVMRLYQEVGSQLREAIVSGRYSVGDRLPPERDIAENFSVSRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
VVREALIMLELEKLVEVRKGSGVYVVNVPTMSLNGESATSIDSGYGPFELLQARQLLESE
HHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
VAAFAAMQATKADIIKMRNAIEQGKAALTAGAIDESADELFHCLLAQSTQNSVLANMVAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
TWQVRKSSAMWQGAHSHTADFSYRWQWLDDHQKILQAVLRRDSKAAKQAMWQHLENVKLK
HHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEE
LLEISDADHPDFDGYLFESAPYQIEE
EEEECCCCCCCCCCEEECCCCCCCCC
>Mature Secondary Structure
MVRSIWYFLRQCLMQEIKVMRLYQEVGSQLREAIVSGRYSVGDRLPPERDIAENFSVSRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
VVREALIMLELEKLVEVRKGSGVYVVNVPTMSLNGESATSIDSGYGPFELLQARQLLESE
HHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
VAAFAAMQATKADIIKMRNAIEQGKAALTAGAIDESADELFHCLLAQSTQNSVLANMVAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
TWQVRKSSAMWQGAHSHTADFSYRWQWLDDHQKILQAVLRRDSKAAKQAMWQHLENVKLK
HHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEE
LLEISDADHPDFDGYLFESAPYQIEE
EEEECCCCCCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]