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The map label for this gene is yehW [H]

Identifier: 218928360

GI number: 218928360

Start: 1348777

End: 1349613

Strand: Direct

Name: yehW [H]

Synonym: YPO1199

Alternate gene names: 218928360

Gene position: 1348777-1349613 (Clockwise)

Preceding gene: 218928359

Following gene: 218928361

Centisome position: 28.98

GC content: 50.3

Gene sequence:

>837_bases
ATGAAGCCAGCAGAAACCAAACCTGATAATACAGCAGTGGGTGATGTGAAAAGTATTAAACCGGGGCTGCGGTTTTGGTT
TTGGCTAAAAGATCCTCTGTGTTGGGCGCTGCTCATCCTGTGTGGGTTGGTCTTCGGTATGACCTCACTACAGCGTTTCT
TTACCGCATTGTTCCCAGAACTTGATCGGCCTATCTATTTGCAAGATACCTTTTTTTCATTGGTGGTCGCTCATGTATTA
CTGGTATTGGCCTCCAGTAGTATTGCTGTTTTCATCGGTGTTACTACCGGGATTGCAGTAACGCGCCCGGCAGGAAAGGA
GTTTCGTTCGGTAGTGGAAACGGTTGTGGCGATGGGGCAAACATTTCCCCCTGTAGCGGTACTCGCCATTGCGGTTCCTG
TGATGGGGTTCAGTGAGAAACCGGCGATTATTGCACTGGTGCTTTATGGCTTATTGCCGATTTTACAAGGCACCATTGCG
GGTATTGAATCCGTTTCGACCAGTATCCGTGAAGTGGCGGCAGGTGTTGGGATGAGTGCGAGGCAGATCCTCTGGCAGGT
GGAATTACCTTTGGCTGCGCCAGTGATTGTGGCGGGTATTCGCACTTCGGTAATCATCAATATAGGTACTGCGGCTATCG
CATCGACAGTAGGGACCAAGACGCTTGGCTCTCCAATTATTATCGGCCTCAGTGGCTTTAATACCGCTTACGTTATTCAG
GGGGCCGCCGTTGTTGCGCTCTTGGCGATTATTACTGATATGATTTTCGACCGTTGGACTCGGCGGTTGTCACGCTGGAG
GGAACGACACTCTCTTTCTGCTCCCCGAACGGATTAA

Upstream 100 bases:

>100_bases
TTGTTTCCCGTCAGACGGATAAATTACCGGTTGCTGATGAACACGGGCAGCCACTAGGCGTTCTCTATTTTGCTGATTTG
GTTGCGAATAAGGAAAGAGT

Downstream 100 bases:

>100_bases
TGATGCTATCAATGGCGATTAATGGTGCTACCAATGGTTCTCCTTGATCTGAATTATCGATGTGAGCCAGTGGTTCGGTA
TTCACTCTTTTTACTTGGTC

Product: putative ABC transport integral membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MKPAETKPDNTAVGDVKSIKPGLRFWFWLKDPLCWALLILCGLVFGMTSLQRFFTALFPELDRPIYLQDTFFSLVVAHVL
LVLASSSIAVFIGVTTGIAVTRPAGKEFRSVVETVVAMGQTFPPVAVLAIAVPVMGFSEKPAIIALVLYGLLPILQGTIA
GIESVSTSIREVAAGVGMSARQILWQVELPLAAPVIVAGIRTSVIINIGTAAIASTVGTKTLGSPIIIGLSGFNTAYVIQ
GAAVVALLAIITDMIFDRWTRRLSRWRERHSLSAPRTD

Sequences:

>Translated_278_residues
MKPAETKPDNTAVGDVKSIKPGLRFWFWLKDPLCWALLILCGLVFGMTSLQRFFTALFPELDRPIYLQDTFFSLVVAHVL
LVLASSSIAVFIGVTTGIAVTRPAGKEFRSVVETVVAMGQTFPPVAVLAIAVPVMGFSEKPAIIALVLYGLLPILQGTIA
GIESVSTSIREVAAGVGMSARQILWQVELPLAAPVIVAGIRTSVIINIGTAAIASTVGTKTLGSPIIIGLSGFNTAYVIQ
GAAVVALLAIITDMIFDRWTRRLSRWRERHSLSAPRTD
>Mature_278_residues
MKPAETKPDNTAVGDVKSIKPGLRFWFWLKDPLCWALLILCGLVFGMTSLQRFFTALFPELDRPIYLQDTFFSLVVAHVL
LVLASSSIAVFIGVTTGIAVTRPAGKEFRSVVETVVAMGQTFPPVAVLAIAVPVMGFSEKPAIIALVLYGLLPILQGTIA
GIESVSTSIREVAAGVGMSARQILWQVELPLAAPVIVAGIRTSVIINIGTAAIASTVGTKTLGSPIIIGLSGFNTAYVIQ
GAAVVALLAIITDMIFDRWTRRLSRWRERHSLSAPRTD

Specific function: May be part of an ABC transporter complex involved in uptake of osmoprotectant molecules. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=237, Percent_Identity=62.8691983122363, Blast_Score=282, Evalue=2e-77,
Organism=Escherichia coli, GI1788451, Length=204, Percent_Identity=32.843137254902, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789033, Length=185, Percent_Identity=29.1891891891892, Blast_Score=74, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29801; Mature: 29801

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPAETKPDNTAVGDVKSIKPGLRFWFWLKDPLCWALLILCGLVFGMTSLQRFFTALFPE
CCCCCCCCCCCCCCCHHHCCCCHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDRPIYLQDTFFSLVVAHVLLVLASSSIAVFIGVTTGIAVTRPAGKEFRSVVETVVAMGQ
CCCCEEEHHHHHHHHHHHHHHHHHCCCEEEEEEEECCEEEECCCCHHHHHHHHHHHHCCC
TFPPVAVLAIAVPVMGFSEKPAIIALVLYGLLPILQGTIAGIESVSTSIREVAAGVGMSA
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
RQILWQVELPLAAPVIVAGIRTSVIINIGTAAIASTVGTKTLGSPIIIGLSGFNTAYVIQ
HHHHHHCCCCHHHHHHHHHHHHHEEEECHHHHHHHHHCHHHCCCCEEEEECCCCCHHHHH
GAAVVALLAIITDMIFDRWTRRLSRWRERHSLSAPRTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKPAETKPDNTAVGDVKSIKPGLRFWFWLKDPLCWALLILCGLVFGMTSLQRFFTALFPE
CCCCCCCCCCCCCCCHHHCCCCHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDRPIYLQDTFFSLVVAHVLLVLASSSIAVFIGVTTGIAVTRPAGKEFRSVVETVVAMGQ
CCCCEEEHHHHHHHHHHHHHHHHHCCCEEEEEEEECCEEEECCCCHHHHHHHHHHHHCCC
TFPPVAVLAIAVPVMGFSEKPAIIALVLYGLLPILQGTIAGIESVSTSIREVAAGVGMSA
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
RQILWQVELPLAAPVIVAGIRTSVIINIGTAAIASTVGTKTLGSPIIIGLSGFNTAYVIQ
HHHHHHCCCCHHHHHHHHHHHHHEEEECHHHHHHHHHCHHHCCCCEEEEECCCCCHHHHH
GAAVVALLAIITDMIFDRWTRRLSRWRERHSLSAPRTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]