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The map label for this gene is pbpG [H]

Identifier: 218928339

GI number: 218928339

Start: 1324904

End: 1325839

Strand: Direct

Name: pbpG [H]

Synonym: YPO1176

Alternate gene names: 218928339

Gene position: 1324904-1325839 (Clockwise)

Preceding gene: 218928338

Following gene: 218928341

Centisome position: 28.47

GC content: 45.73

Gene sequence:

>936_bases
ATGTATGTAAAAATCCGTTTTGCACTATTGAGCTTTTTGCTTTTATCCACCGGTATCAGTGTTGCGCCTTTGGCCATTGC
CCGGGGATCAGCGGTTGAGGTTAAAGGGACGGCACCTTTGGAATTGGCATCGGGTAGCGCTATGGTGGTTGATTTACAAA
CGAATAAAGTCATTTATGCCAATAATGCAGATAAAGTTGTGCCTATTGCCTCAATCACTAAACTGATGACGGCCATGGTG
GTATTAGATGCCAAATTGCCTCTTGATGAAATTCTCTCCGTAGATATTGATCAAACTAAAGAGTTGAAAGGGGTGTTTTC
CCGCGTTCGTGTTAACAGTGAAATTAGCCGTAAGGACATGCTGCTACTGACACTGATGTCGTCAGAAAATCGTGCTGCGG
CCAGCCTGGCCCACCATTACCCTGGGGGCTACAACGCATTTATAAAAGCCATGAATGCAAAAGCCAAGTCTTTGGGCATG
AACAGTACGCATTATGTTGAGCCAACAGGGCTGTCGATTAATAACGTCTCGACAGCGCGTGATTTAGCCAAATTACTGAT
GGCGACCAAACAGTATCCGTTAATTGGCCAGTTAAGTACCACTACCGAAAAAATGGCTACTTTCCGTGAACCAAATTATA
CGTTGCCATTCCGCAATACTAACCATTTGGTTTATAACGACAAATGGAATATTCAACTGACCAAAACCGGTTTTACCAAC
CAGGCTGGACACTGCTTGGTCATGCGTACCGTGATTGGCAAGCGGCCGGTCGCATTGGTGGTATTGGATGCTTTTGGTAA
ATATACCCATTTTGCGGATGCAAACCGCCTGCGTAGCTGGATCGAAACAGGTAAAGCGGCGCCCATCCCTGGTGCTGCCA
AAAGTTATCGTCAGCAAAAAGATTCACAGGGCCGTTTAGCGCAGGTATCAGAATAA

Upstream 100 bases:

>100_bases
CAATCATTTAAAGAAACCGTGATGCGTGCGTCAGGCCGGTAATTTATAATGCGCGACACCAATCATGTCCACTCCCGATA
ATTTATTTAAGCTGACAAAC

Downstream 100 bases:

>100_bases
GAGCAGCGCATCGCGACTGAGAAGCGGAATTTGCTAGCAGAGGCAAATTCCGCTTTAGTGACTAATTGTTTGCTTTCAGA
TAATGCCTAAGCCTAATGGT

Product: D-alanyl-D-alanine endopeptidase

Products: NA

Alternate protein names: DD-endopeptidase; Penicillin-binding protein 7; PBP-7 [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MYVKIRFALLSFLLLSTGISVAPLAIARGSAVEVKGTAPLELASGSAMVVDLQTNKVIYANNADKVVPIASITKLMTAMV
VLDAKLPLDEILSVDIDQTKELKGVFSRVRVNSEISRKDMLLLTLMSSENRAAASLAHHYPGGYNAFIKAMNAKAKSLGM
NSTHYVEPTGLSINNVSTARDLAKLLMATKQYPLIGQLSTTTEKMATFREPNYTLPFRNTNHLVYNDKWNIQLTKTGFTN
QAGHCLVMRTVIGKRPVALVVLDAFGKYTHFADANRLRSWIETGKAAPIPGAAKSYRQQKDSQGRLAQVSE

Sequences:

>Translated_311_residues
MYVKIRFALLSFLLLSTGISVAPLAIARGSAVEVKGTAPLELASGSAMVVDLQTNKVIYANNADKVVPIASITKLMTAMV
VLDAKLPLDEILSVDIDQTKELKGVFSRVRVNSEISRKDMLLLTLMSSENRAAASLAHHYPGGYNAFIKAMNAKAKSLGM
NSTHYVEPTGLSINNVSTARDLAKLLMATKQYPLIGQLSTTTEKMATFREPNYTLPFRNTNHLVYNDKWNIQLTKTGFTN
QAGHCLVMRTVIGKRPVALVVLDAFGKYTHFADANRLRSWIETGKAAPIPGAAKSYRQQKDSQGRLAQVSE
>Mature_311_residues
MYVKIRFALLSFLLLSTGISVAPLAIARGSAVEVKGTAPLELASGSAMVVDLQTNKVIYANNADKVVPIASITKLMTAMV
VLDAKLPLDEILSVDIDQTKELKGVFSRVRVNSEISRKDMLLLTLMSSENRAAASLAHHYPGGYNAFIKAMNAKAKSLGM
NSTHYVEPTGLSINNVSTARDLAKLLMATKQYPLIGQLSTTTEKMATFREPNYTLPFRNTNHLVYNDKWNIQLTKTGFTN
QAGHCLVMRTVIGKRPVALVVLDAFGKYTHFADANRLRSWIETGKAAPIPGAAKSYRQQKDSQGRLAQVSE

Specific function: Cell wall formation. May play a specialized role in remodeling the cell wall. Specifically hydrolyze the DD- diaminopimelate-alanine bonds in high-molecular-mass murein sacculi [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI87082054, Length=256, Percent_Identity=82.03125, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1787062, Length=285, Percent_Identity=30.1754385964912, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082022, Length=255, Percent_Identity=28.2352941176471, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786851, Length=285, Percent_Identity=24.5614035087719, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR018044
- InterPro:   IPR001967 [H]

Pfam domain/function: PF00768 Peptidase_S11 [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 34003; Mature: 34003

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVKIRFALLSFLLLSTGISVAPLAIARGSAVEVKGTAPLELASGSAMVVDLQTNKVIYA
CEEEEHHHHHHHHHHHCCCCEEEHEEECCCEEEEECCCCEEECCCCEEEEEEECCEEEEE
NNADKVVPIASITKLMTAMVVLDAKLPLDEILSVDIDQTKELKGVFSRVRVNSEISRKDM
CCCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCE
LLLTLMSSENRAAASLAHHYPGGYNAFIKAMNAKAKSLGMNSTHYVEPTGLSINNVSTAR
EEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHCCCCCCEEECCCCCEECCCHHHH
DLAKLLMATKQYPLIGQLSTTTEKMATFREPNYTLPFRNTNHLVYNDKWNIQLTKTGFTN
HHHHHHHHHCCCCCEECCHHHHHHHHHHCCCCEEECCCCCCEEEECCCEEEEEEECCCCC
QAGHCLVMRTVIGKRPVALVVLDAFGKYTHFADANRLRSWIETGKAAPIPGAAKSYRQQK
CCCCEEEEEHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHC
DSQGRLAQVSE
CCCCCEEECCC
>Mature Secondary Structure
MYVKIRFALLSFLLLSTGISVAPLAIARGSAVEVKGTAPLELASGSAMVVDLQTNKVIYA
CEEEEHHHHHHHHHHHCCCCEEEHEEECCCEEEEECCCCEEECCCCEEEEEEECCEEEEE
NNADKVVPIASITKLMTAMVVLDAKLPLDEILSVDIDQTKELKGVFSRVRVNSEISRKDM
CCCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCE
LLLTLMSSENRAAASLAHHYPGGYNAFIKAMNAKAKSLGMNSTHYVEPTGLSINNVSTAR
EEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHCCCCCCEEECCCCCEECCCHHHH
DLAKLLMATKQYPLIGQLSTTTEKMATFREPNYTLPFRNTNHLVYNDKWNIQLTKTGFTN
HHHHHHHHHCCCCCEECCHHHHHHHHHHCCCCEEECCCCCCEEEECCCEEEEEEECCCCC
QAGHCLVMRTVIGKRPVALVVLDAFGKYTHFADANRLRSWIETGKAAPIPGAAKSYRQQK
CCCCEEEEEHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHC
DSQGRLAQVSE
CCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 6386470; 7721700; 7925376 [H]