Click here to switch to the map view.

The map label for this gene is sgrR

Identifier: 218927723

GI number: 218927723

Start: 567926

End: 569587

Strand: Reverse

Name: sgrR

Synonym: YPO0524

Alternate gene names: 218927723

Gene position: 569587-567926 (Counterclockwise)

Preceding gene: 218927725

Following gene: 218927721

Centisome position: 12.24

GC content: 51.08

Gene sequence:

>1662_bases
ATGTCTACCTCGCGCCTGCAACAACAATTTATTCGTCTCTGGCAACGCTATAACGGACAGTCAACGGAAACCACATTGCA
GGCGCTGGCTGAAGTGCTGAATTGTTCACGCCGCCATGTACGTTCTCTGCTGGGCAAGATGCAGCACGCGGGCTGGCTCG
ATTGGCAGGCTGAAGCTGGCCGAGGAAAACGCTCACAATTGATCTTCTTGCGTTCCGGGCTGGCGCTGCAACAACAACGG
GCTGAAGAGTTGCTGGAGCAGGATCATATTGATCAGTTAGTCCAACTGGTCGGTGATAAAAAAGCGGTACGCCAAATGTT
GCTGTCCCAGTTGGGACGTAGCTTCCGGCAAGGAAAACATATTCTGCGGGTGCTCTATTACCGCCCATTGGAGAACTTAT
TACCCGGCACCGCCCTACGCCGCTCTGAAACCCATATGGTGCGGCAAATTTTTAACGGGCTGACACGGATAAATGAGGAA
AATGGGGAACTCGAACCGGACTTATCTCATCACTGGCAAGCGATCACCCCCTTGCATTGGCGCTTTTATTTGCGACCAGC
CATTCATTTCCACCATGGCCGGGAACTGGAAATGAGTGATGTGATTAGCAGCCTGACCCGCCTGATCCCCCAACCCCTGT
TTTCTCATATTGCGGAGGTGCGTTCACCGACACCTTATGTGATTGATGTTTATCTCCATTCGCCAGATCACTGGTTGCCA
TGGCTACTGGGCAGCGTTCACGCCATGATTTTGCCGCAAGAGTGGGAAACTCAGCCCGATTTTCACCGACAGCCTATTGG
TACCGGCCCTTATTCCGTGATCCGCAATCATCACAGCCAGCTGAAAATTCAGGCATTCGATAACTATTTTGGTTTCCGGG
CACTGATTGATGAGGTCAATATCTGGGTACTCCCAGAACTCTCCGAAGAATTGGTGTATTCCGGGGTGCAATTGCAAGCC
GACGATACGGGTAAAAATGAGCTGGAGAGCCGTTTAGAGGAAGGTTGCTACTTCTTACTGTTCGACCAACGATCCCCTCA
GGCCTGCACCCCGGAGATCCGCCGTTGGTTATGTGAATTGATCACACCGATAGCGTTACTCAGCCACGCCGCTCCCTTCT
ATCAACGTTACTGGTCACCGGCCTATGGCATGTTGCCACGCTGGCACCATAACCGACTCACCACTCAAGAGCCAAAACCC
GAAGGGCTGAACGAGCTGACACTGACGTTTTACAGCGAACATTCAGAGTTTGATGCCATCAGCCAGACACTGACCCAGTT
ATTGGCTGCTCAGGGCGTGACGTTAAAGATACAAGTCTTGGACTACACCCGCTGGTATCAGGGGGATGCACAAAGCGATA
TCTGGCTCGGCAGCGCTAACTTTTACTTGCCACTCGAATTCTCGCTATTTGCCACCCTCTATGAAATGCCGCTACTACAA
CATTGTCTGAGCGAAGAACTGCATCAAGATATTGAATCCTGGCGCAATAATACCTTACTCATGGCCGATTGGAGCCAACG
ACTGGTAAGCCAGCATCAATTCCATCCGCTATTTCATCATTGGTTAGAATTATACGGTCAACACAGTATGCGGGGAGTGC
GTATGAATACACTCGGCTGGTTTGATTTTAAATCCGCATGGTTTACCCCACCAGAGGCCTAG

Upstream 100 bases:

>100_bases
GCATAGACGTTGTCACGATAACCCGCTTTTCTTGGGGGTTAGTATCTGCGTAATATAGGGAAAGAAAAATTGATGAGATT
TCCCAAGGAGTTCCTCTTTT

Downstream 100 bases:

>100_bases
GGCGGCGTTGACTCACACGGCGCTCCCCCTGAATTTATTATACAAACGGGCTGCACTACCCCTTTCAATAATTCCATTTA
TGAGAACGAGTTAAATACTC

Product: transcriptional regulator SgrR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MSTSRLQQQFIRLWQRYNGQSTETTLQALAEVLNCSRRHVRSLLGKMQHAGWLDWQAEAGRGKRSQLIFLRSGLALQQQR
AEELLEQDHIDQLVQLVGDKKAVRQMLLSQLGRSFRQGKHILRVLYYRPLENLLPGTALRRSETHMVRQIFNGLTRINEE
NGELEPDLSHHWQAITPLHWRFYLRPAIHFHHGRELEMSDVISSLTRLIPQPLFSHIAEVRSPTPYVIDVYLHSPDHWLP
WLLGSVHAMILPQEWETQPDFHRQPIGTGPYSVIRNHHSQLKIQAFDNYFGFRALIDEVNIWVLPELSEELVYSGVQLQA
DDTGKNELESRLEEGCYFLLFDQRSPQACTPEIRRWLCELITPIALLSHAAPFYQRYWSPAYGMLPRWHHNRLTTQEPKP
EGLNELTLTFYSEHSEFDAISQTLTQLLAAQGVTLKIQVLDYTRWYQGDAQSDIWLGSANFYLPLEFSLFATLYEMPLLQ
HCLSEELHQDIESWRNNTLLMADWSQRLVSQHQFHPLFHHWLELYGQHSMRGVRMNTLGWFDFKSAWFTPPEA

Sequences:

>Translated_553_residues
MSTSRLQQQFIRLWQRYNGQSTETTLQALAEVLNCSRRHVRSLLGKMQHAGWLDWQAEAGRGKRSQLIFLRSGLALQQQR
AEELLEQDHIDQLVQLVGDKKAVRQMLLSQLGRSFRQGKHILRVLYYRPLENLLPGTALRRSETHMVRQIFNGLTRINEE
NGELEPDLSHHWQAITPLHWRFYLRPAIHFHHGRELEMSDVISSLTRLIPQPLFSHIAEVRSPTPYVIDVYLHSPDHWLP
WLLGSVHAMILPQEWETQPDFHRQPIGTGPYSVIRNHHSQLKIQAFDNYFGFRALIDEVNIWVLPELSEELVYSGVQLQA
DDTGKNELESRLEEGCYFLLFDQRSPQACTPEIRRWLCELITPIALLSHAAPFYQRYWSPAYGMLPRWHHNRLTTQEPKP
EGLNELTLTFYSEHSEFDAISQTLTQLLAAQGVTLKIQVLDYTRWYQGDAQSDIWLGSANFYLPLEFSLFATLYEMPLLQ
HCLSEELHQDIESWRNNTLLMADWSQRLVSQHQFHPLFHHWLELYGQHSMRGVRMNTLGWFDFKSAWFTPPEA
>Mature_552_residues
STSRLQQQFIRLWQRYNGQSTETTLQALAEVLNCSRRHVRSLLGKMQHAGWLDWQAEAGRGKRSQLIFLRSGLALQQQRA
EELLEQDHIDQLVQLVGDKKAVRQMLLSQLGRSFRQGKHILRVLYYRPLENLLPGTALRRSETHMVRQIFNGLTRINEEN
GELEPDLSHHWQAITPLHWRFYLRPAIHFHHGRELEMSDVISSLTRLIPQPLFSHIAEVRSPTPYVIDVYLHSPDHWLPW
LLGSVHAMILPQEWETQPDFHRQPIGTGPYSVIRNHHSQLKIQAFDNYFGFRALIDEVNIWVLPELSEELVYSGVQLQAD
DTGKNELESRLEEGCYFLLFDQRSPQACTPEIRRWLCELITPIALLSHAAPFYQRYWSPAYGMLPRWHHNRLTTQEPKPE
GLNELTLTFYSEHSEFDAISQTLTQLLAAQGVTLKIQVLDYTRWYQGDAQSDIWLGSANFYLPLEFSLFATLYEMPLLQH
CLSEELHQDIESWRNNTLLMADWSQRLVSQHQFHPLFHHWLELYGQHSMRGVRMNTLGWFDFKSAWFTPPEA

Specific function: Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding

COG id: COG4533

COG function: function code R; ABC-type uncharacterized transport system, periplasmic component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1786256, Length=552, Percent_Identity=62.8623188405797, Blast_Score=728, Evalue=0.0,
Organism=Escherichia coli, GI1786650, Length=572, Percent_Identity=29.020979020979, Blast_Score=201, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SGRR_YERPA (Q1C1Y8)

Other databases:

- EMBL:   CP000308
- RefSeq:   YP_653479.1
- ProteinModelPortal:   Q1C1Y8
- STRING:   Q1C1Y8
- GeneID:   4121513
- GenomeReviews:   CP000308_GR
- KEGG:   ypa:YPA_3572
- eggNOG:   COG4533
- HOGENOM:   HBG303837
- OMA:   QRSMRGV
- ProtClustDB:   PRK13626
- BioCyc:   YPES360102:YPA_3572-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_01449
- InterPro:   IPR000914

Pfam domain/function: PF00496 SBP_bac_5

EC number: NA

Molecular weight: Translated: 64850; Mature: 64718

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS01117 HTH_MARR_1; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSRLQQQFIRLWQRYNGQSTETTLQALAEVLNCSRRHVRSLLGKMQHAGWLDWQAEAG
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RGKRSQLIFLRSGLALQQQRAEELLEQDHIDQLVQLVGDKKAVRQMLLSQLGRSFRQGKH
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ILRVLYYRPLENLLPGTALRRSETHMVRQIFNGLTRINEENGELEPDLSHHWQAITPLHW
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHH
RFYLRPAIHFHHGRELEMSDVISSLTRLIPQPLFSHIAEVRSPTPYVIDVYLHSPDHWLP
HEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHH
WLLGSVHAMILPQEWETQPDFHRQPIGTGPYSVIRNHHSQLKIQAFDNYFGFRALIDEVN
HHHHHHHHEECCCCCCCCCCCCCCCCCCCHHHHHHCCCHHEEEEEHHHHHHHHHHHHHCC
IWVLPELSEELVYSGVQLQADDTGKNELESRLEEGCYFLLFDQRSPQACTPEIRRWLCEL
EEECCCHHHHHHHCCCEEEECCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHH
ITPIALLSHAAPFYQRYWSPAYGMLPRWHHNRLTTQEPKPEGLNELTLTFYSEHSEFDAI
HHHHHHHHHCCHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHH
SQTLTQLLAAQGVTLKIQVLDYTRWYQGDAQSDIWLGSANFYLPLEFSLFATLYEMPLLQ
HHHHHHHHHHCCCEEEEEEEECHHHCCCCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHH
HCLSEELHQDIESWRNNTLLMADWSQRLVSQHQFHPLFHHWLELYGQHSMRGVRMNTLGW
HHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEECCCCC
FDFKSAWFTPPEA
EECCCCCCCCCCC
>Mature Secondary Structure 
STSRLQQQFIRLWQRYNGQSTETTLQALAEVLNCSRRHVRSLLGKMQHAGWLDWQAEAG
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RGKRSQLIFLRSGLALQQQRAEELLEQDHIDQLVQLVGDKKAVRQMLLSQLGRSFRQGKH
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ILRVLYYRPLENLLPGTALRRSETHMVRQIFNGLTRINEENGELEPDLSHHWQAITPLHW
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHH
RFYLRPAIHFHHGRELEMSDVISSLTRLIPQPLFSHIAEVRSPTPYVIDVYLHSPDHWLP
HEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHH
WLLGSVHAMILPQEWETQPDFHRQPIGTGPYSVIRNHHSQLKIQAFDNYFGFRALIDEVN
HHHHHHHHEECCCCCCCCCCCCCCCCCCCHHHHHHCCCHHEEEEEHHHHHHHHHHHHHCC
IWVLPELSEELVYSGVQLQADDTGKNELESRLEEGCYFLLFDQRSPQACTPEIRRWLCEL
EEECCCHHHHHHHCCCEEEECCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHH
ITPIALLSHAAPFYQRYWSPAYGMLPRWHHNRLTTQEPKPEGLNELTLTFYSEHSEFDAI
HHHHHHHHHCCHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHH
SQTLTQLLAAQGVTLKIQVLDYTRWYQGDAQSDIWLGSANFYLPLEFSLFATLYEMPLLQ
HHHHHHHHHHCCCEEEEEEEECHHHCCCCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHH
HCLSEELHQDIESWRNNTLLMADWSQRLVSQHQFHPLFHHWLELYGQHSMRGVRMNTLGW
HHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEECCCCC
FDFKSAWFTPPEA
EECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA