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The map label for this gene is dipZ

Identifier: 218927548

GI number: 218927548

Start: 354798

End: 356585

Strand: Reverse

Name: dipZ

Synonym: YPO0345

Alternate gene names: 218927548

Gene position: 356585-354798 (Counterclockwise)

Preceding gene: 218927549

Following gene: 218927544

Centisome position: 7.66

GC content: 52.24

Gene sequence:

>1788_bases
ATGGCTCAACGCTTCATTACTCTGATCCTGCTGCTGTGCAGCGTATTACTCGCCCCGCACAGCGCCCAGTCCTCACTCTT
TGGTGAGAACGCCTCTTTTGGTACCAAAAACAGTCAGAGCCGGTTTATTCCGGTCGATCAAGCGTTCGCCTTTGATTTCC
ACCAGCAAGGCGATCAGCTGAATCTGAGTTGGCAAATCCATCCCGGTTACTACCTGTATCGCCAGCAAATAAAAATTGTA
CCGCAGCAAGCGGCTCTGGGAGCATTCACCCTGCCGGAAGGCATTACGCATCATGATGAGTTCTATGGTGAAGTCGAGAT
TTTCAAGCAGCAGTTAACCCTGAAAATCCCCATTACGCAGGCGGCTGAACAGGCTAGCGTCAGTGTGACCTATCAGGGCT
GTGCGGAAGCCGGCTTCTGTTATCCACCAGAAACGCGGGTGATCCCACTTGATGTGGTCGTTGCTGCTTCCACGGCTTCA
GGCACTGCTGCCGTCAATTCGTCCGCTACCGTCAATCCACCAGCGACAACACAGCCAGAGGGCGATGCCACACCAGTACC
GTCTACGTTACCCTTCTCTCCCTTGTGGGCGCTGCTAATCGGTATCGGGATTGCGTTTACCCCCTGTGTTTTACCGATGT
ATCCATTGATTTCAGCCGTCATTCTTGGCCGTGAAAAACCACACAGCCAACGGCGAATACTGATATTAGCGGTGGTGTAC
GTACAAGGGATGGCGCTGACCTATACCTTGCTAGGGTTAGTGGTTGCGGCAGCAGGTTTACAGTTCCAGGCCGCGCTACA
GCATCCTTATGTGTTGATTGGCTTGTCGGTATTATTCGTGCTGTTGGCATTATCAATGTTCGGCCTGTATTCATTGCAAT
TACCTTCATCGTTACAGACCCGCCTGACACAGTGGAGTAATAGCCAACGTGGCGGCTCACTGGCCGGTGTATTTGCGATG
GGTGCACTGGCGGGTCTGATTTGTTCTCCCTGCACTACCGCACCGCTGAGCGCGATCCTGCTCTATATTGCCCAAAGCGG
TAATATGCTGGCCGGTGGTGGGACCTTGTACCTATATGCGCTTGGGATGGGGATCCCGCTAGTGGTTGTCACCCTGTTCG
GCAACAAGCTCATTCCACGCAGCGGTCCGTGGATGCAATATGTCAAAGAGGCTTTTGGTTTTGTGATCCTGGCGCTGCCC
GTGTTTTTACTGGAAAGGGTGCTGGGGGATGTCTGGGGTTTACGTTTATGGAGCCTGCTGGCCGTCGCGTTCTTTGGCTG
GGCGTTTGTATTGAGCCTGAAAGCGCACGCTGGTTGGGTGCGGGTCTGCCAGTTATTGCTCTTGGCCGCACTGTTGATCG
TGGCTCGCCCCTTGCAAGATTGGGCCTTTAACGGCAACACGCAGCAGAACGCAGTCAAGCATATAAACTTTCAACCAGTG
GCTAATTTACCCCAATTGCAAGCCGTATTAGCGCAGGCGCAGGGTAAACCGGTGATGCTCGATCTGTATGCAGACTGGTG
TGTGGCCTGTAAAGAGTTTGAGAAATACACTTTCAGTGATGATAAGGTCCAGCGCCAGTTAGCCAATACCCTGTTGCTGC
AAGCGGATGTCACCGCCAACAATGCTGAACATGCCACATTATTGAAGAAATTTAACGTGTTAGGTTTACCCACTATTCTG
TTTTTTGATTCTCAGGGCAACGAGATCACTGCCGCACGGGTCACCGGGTTTATGGACGCTGCGCAATTCTTACAGCATTT
ACAAAACACCCCCGCGGTTACAAAATAA

Upstream 100 bases:

>100_bases
ATCAGCAGGCCCTTCTCACTTATATCAAACAACATCACCCCTACCAGACGCCGGAATTACTGGTGCTACCGGTACGAGAC
GGAGATAAAGATTACCTGTC

Downstream 100 bases:

>100_bases
ATAGCTGTCGCCACGGCGAGTAGGTCTCGCCGTGGCATAATCAACGCTCAATCACGACAAGTCATGGTACAACTGCGGCG
TCTGATAACCGTTTTTTCAA

Product: thiol:disulfide interchange protein precursor

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase

Number of amino acids: Translated: 595; Mature: 594

Protein sequence:

>595_residues
MAQRFITLILLLCSVLLAPHSAQSSLFGENASFGTKNSQSRFIPVDQAFAFDFHQQGDQLNLSWQIHPGYYLYRQQIKIV
PQQAALGAFTLPEGITHHDEFYGEVEIFKQQLTLKIPITQAAEQASVSVTYQGCAEAGFCYPPETRVIPLDVVVAASTAS
GTAAVNSSATVNPPATTQPEGDATPVPSTLPFSPLWALLIGIGIAFTPCVLPMYPLISAVILGREKPHSQRRILILAVVY
VQGMALTYTLLGLVVAAAGLQFQAALQHPYVLIGLSVLFVLLALSMFGLYSLQLPSSLQTRLTQWSNSQRGGSLAGVFAM
GALAGLICSPCTTAPLSAILLYIAQSGNMLAGGGTLYLYALGMGIPLVVVTLFGNKLIPRSGPWMQYVKEAFGFVILALP
VFLLERVLGDVWGLRLWSLLAVAFFGWAFVLSLKAHAGWVRVCQLLLLAALLIVARPLQDWAFNGNTQQNAVKHINFQPV
ANLPQLQAVLAQAQGKPVMLDLYADWCVACKEFEKYTFSDDKVQRQLANTLLLQADVTANNAEHATLLKKFNVLGLPTIL
FFDSQGNEITAARVTGFMDAAQFLQHLQNTPAVTK

Sequences:

>Translated_595_residues
MAQRFITLILLLCSVLLAPHSAQSSLFGENASFGTKNSQSRFIPVDQAFAFDFHQQGDQLNLSWQIHPGYYLYRQQIKIV
PQQAALGAFTLPEGITHHDEFYGEVEIFKQQLTLKIPITQAAEQASVSVTYQGCAEAGFCYPPETRVIPLDVVVAASTAS
GTAAVNSSATVNPPATTQPEGDATPVPSTLPFSPLWALLIGIGIAFTPCVLPMYPLISAVILGREKPHSQRRILILAVVY
VQGMALTYTLLGLVVAAAGLQFQAALQHPYVLIGLSVLFVLLALSMFGLYSLQLPSSLQTRLTQWSNSQRGGSLAGVFAM
GALAGLICSPCTTAPLSAILLYIAQSGNMLAGGGTLYLYALGMGIPLVVVTLFGNKLIPRSGPWMQYVKEAFGFVILALP
VFLLERVLGDVWGLRLWSLLAVAFFGWAFVLSLKAHAGWVRVCQLLLLAALLIVARPLQDWAFNGNTQQNAVKHINFQPV
ANLPQLQAVLAQAQGKPVMLDLYADWCVACKEFEKYTFSDDKVQRQLANTLLLQADVTANNAEHATLLKKFNVLGLPTIL
FFDSQGNEITAARVTGFMDAAQFLQHLQNTPAVTK
>Mature_594_residues
AQRFITLILLLCSVLLAPHSAQSSLFGENASFGTKNSQSRFIPVDQAFAFDFHQQGDQLNLSWQIHPGYYLYRQQIKIVP
QQAALGAFTLPEGITHHDEFYGEVEIFKQQLTLKIPITQAAEQASVSVTYQGCAEAGFCYPPETRVIPLDVVVAASTASG
TAAVNSSATVNPPATTQPEGDATPVPSTLPFSPLWALLIGIGIAFTPCVLPMYPLISAVILGREKPHSQRRILILAVVYV
QGMALTYTLLGLVVAAAGLQFQAALQHPYVLIGLSVLFVLLALSMFGLYSLQLPSSLQTRLTQWSNSQRGGSLAGVFAMG
ALAGLICSPCTTAPLSAILLYIAQSGNMLAGGGTLYLYALGMGIPLVVVTLFGNKLIPRSGPWMQYVKEAFGFVILALPV
FLLERVLGDVWGLRLWSLLAVAFFGWAFVLSLKAHAGWVRVCQLLLLAALLIVARPLQDWAFNGNTQQNAVKHINFQPVA
NLPQLQAVLAQAQGKPVMLDLYADWCVACKEFEKYTFSDDKVQRQLANTLLLQADVTANNAEHATLLKKFNVLGLPTILF
FDSQGNEITAARVTGFMDAAQFLQHLQNTPAVTK

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain

Homologues:

Organism=Escherichia coli, GI1790578, Length=589, Percent_Identity=63.8370118845501, Blast_Score=754, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBD_YERPA (Q1C0X4)

Other databases:

- EMBL:   CP000308
- RefSeq:   YP_653843.1
- ProteinModelPortal:   Q1C0X4
- STRING:   Q1C0X4
- GeneID:   4119501
- GenomeReviews:   CP000308_GR
- KEGG:   ypa:YPA_3937
- eggNOG:   COG4232
- HOGENOM:   HBG640883
- OMA:   HTDEYFG
- ProtClustDB:   PRK00293
- BioCyc:   YPES360102:YPA_3937-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00399
- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin; SSF52833 Thiordxn-like_fd

EC number: =1.8.1.8

Molecular weight: Translated: 64507; Mature: 64376

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS00194 THIOREDOXIN_1; PS51352 THIOREDOXIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb25b330)-; HASH(0xb26d90c)-; HASH(0xc21f05c)-; HASH(0xbfa7fec)-; HASH(0xb00cdd4)-; HASH(0xb2f7574)-; HASH(0xc3f5374)-; HASH(0xc1e6ad4)-; HASH(0xc791504)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRFITLILLLCSVLLAPHSAQSSLFGENASFGTKNSQSRFIPVDQAFAFDFHQQGDQL
CHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCCEE
NLSWQIHPGYYLYRQQIKIVPQQAALGAFTLPEGITHHDEFYGEVEIFKQQLTLKIPITQ
EEEEEECCCCCEEEHHHHCCCHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHEEEECCHH
AAEQASVSVTYQGCAEAGFCYPPETRVIPLDVVVAASTASGTAAVNSSATVNPPATTQPE
HHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEEEECCCCCCEEECCCCCCCCCCCCCCC
GDATPVPSTLPFSPLWALLIGIGIAFTPCVLPMYPLISAVILGREKPHSQRRILILAVVY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
VQGMALTYTLLGLVVAAAGLQFQAALQHPYVLIGLSVLFVLLALSMFGLYSLQLPSSLQT
HHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RLTQWSNSQRGGSLAGVFAMGALAGLICSPCTTAPLSAILLYIAQSGNMLAGGGTLYLYA
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCEEEEHH
LGMGIPLVVVTLFGNKLIPRSGPWMQYVKEAFGFVILALPVFLLERVLGDVWGLRLWSLL
HHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAFFGWAFVLSLKAHAGWVRVCQLLLLAALLIVARPLQDWAFNGNTQQNAVKHINFQPV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHCCCCCCC
ANLPQLQAVLAQAQGKPVMLDLYADWCVACKEFEKYTFSDDKVQRQLANTLLLQADVTAN
CCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEECCCCC
NAEHATLLKKFNVLGLPTILFFDSQGNEITAARVTGFMDAAQFLQHLQNTPAVTK
CCHHHHHHHHHCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure 
AQRFITLILLLCSVLLAPHSAQSSLFGENASFGTKNSQSRFIPVDQAFAFDFHQQGDQL
HHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCCEE
NLSWQIHPGYYLYRQQIKIVPQQAALGAFTLPEGITHHDEFYGEVEIFKQQLTLKIPITQ
EEEEEECCCCCEEEHHHHCCCHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHEEEECCHH
AAEQASVSVTYQGCAEAGFCYPPETRVIPLDVVVAASTASGTAAVNSSATVNPPATTQPE
HHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEEEECCCCCCEEECCCCCCCCCCCCCCC
GDATPVPSTLPFSPLWALLIGIGIAFTPCVLPMYPLISAVILGREKPHSQRRILILAVVY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
VQGMALTYTLLGLVVAAAGLQFQAALQHPYVLIGLSVLFVLLALSMFGLYSLQLPSSLQT
HHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RLTQWSNSQRGGSLAGVFAMGALAGLICSPCTTAPLSAILLYIAQSGNMLAGGGTLYLYA
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCEEEEHH
LGMGIPLVVVTLFGNKLIPRSGPWMQYVKEAFGFVILALPVFLLERVLGDVWGLRLWSLL
HHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAFFGWAFVLSLKAHAGWVRVCQLLLLAALLIVARPLQDWAFNGNTQQNAVKHINFQPV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHCCCCCCC
ANLPQLQAVLAQAQGKPVMLDLYADWCVACKEFEKYTFSDDKVQRQLANTLLLQADVTAN
CCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEECCCCC
NAEHATLLKKFNVLGLPTILFFDSQGNEITAARVTGFMDAAQFLQHLQNTPAVTK
CCHHHHHHHHHCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA