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The map label for this gene is pabA [H]

Identifier: 218927380

GI number: 218927380

Start: 188810

End: 189385

Strand: Direct

Name: pabA [H]

Synonym: YPO0169

Alternate gene names: 218927380

Gene position: 188810-189385 (Clockwise)

Preceding gene: 218927379

Following gene: 218927381

Centisome position: 4.06

GC content: 52.08

Gene sequence:

>576_bases
ATGCTACTGCTGATCGACAACTACGATTCATTTACTTACAACCTGTACCAGTATTTTTGTGAGCTGGGTACTGAGGTGAT
GGTTAAGCGCAACGATGAGTTGCAACTGACGGATATTGAACAACTGGCTCCCTCACATGTGGTGATCTCTCCCGGCCCTT
GTACCCCTAACGAGGCTGGGATCTCATTGGCGGTTATCCGCCACTTTGCCGATAAACTGCCTATTCTGGGGGTCTGCCTT
GGTCATCAGGCTCTGGGGCAGGCTTTTGGTGCGCGCGTGGTGCGTGCGCGTCAGGTGATGCACGGCAAAACCTCGGCGAT
TTGCCATTCTGGGCAAGGGGTTTTTCGCGGGCTTAATCAGCCATTGACGGTGACCCGTTACCACTCTTTAGTCATTGCCA
CCGACTCCCTACCGGGCCGTTTTGAGCTGACTGCCTGGACGGAGCGGGGCGGTGAGATGGATGAGATTATGGGGATTCGC
CATCGCACATTGCCACTGGAAGGGGTGCAATTCCATCCAGAAAGTATTCTCAGTGAACAGGGCCATCAATTACTGGATAA
TTTTCTTAAAAATTAA

Upstream 100 bases:

>100_bases
TTGGGGTATAGATAATTGGGGTATAGATAAAAATGAATAGTGGGTGTTGGGAATCTATTAAATCATTTATAACTCTAATA
ATCAGTGGGATAAATTAACG

Downstream 100 bases:

>100_bases
TCGGTTGGGCCAATATTATCCCATGACATCATTTATCATTTGCTTGCGGATGATTTTTTATGCATATTTTGTGAGTATAT
TTTCACGCATCAATAAATAA

Product: para-aminobenzoate synthase component II

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MLLLIDNYDSFTYNLYQYFCELGTEVMVKRNDELQLTDIEQLAPSHVVISPGPCTPNEAGISLAVIRHFADKLPILGVCL
GHQALGQAFGARVVRARQVMHGKTSAICHSGQGVFRGLNQPLTVTRYHSLVIATDSLPGRFELTAWTERGGEMDEIMGIR
HRTLPLEGVQFHPESILSEQGHQLLDNFLKN

Sequences:

>Translated_191_residues
MLLLIDNYDSFTYNLYQYFCELGTEVMVKRNDELQLTDIEQLAPSHVVISPGPCTPNEAGISLAVIRHFADKLPILGVCL
GHQALGQAFGARVVRARQVMHGKTSAICHSGQGVFRGLNQPLTVTRYHSLVIATDSLPGRFELTAWTERGGEMDEIMGIR
HRTLPLEGVQFHPESILSEQGHQLLDNFLKN
>Mature_191_residues
MLLLIDNYDSFTYNLYQYFCELGTEVMVKRNDELQLTDIEQLAPSHVVISPGPCTPNEAGISLAVIRHFADKLPILGVCL
GHQALGQAFGARVVRARQVMHGKTSAICHSGQGVFRGLNQPLTVTRYHSLVIATDSLPGRFELTAWTERGGEMDEIMGIR
HRTLPLEGVQFHPESILSEQGHQLLDNFLKN

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=189, Percent_Identity=74.0740740740741, Blast_Score=293, Evalue=5e-81,
Organism=Escherichia coli, GI1787517, Length=191, Percent_Identity=42.9319371727749, Blast_Score=143, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6322638, Length=189, Percent_Identity=47.6190476190476, Blast_Score=189, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6324361, Length=214, Percent_Identity=32.7102803738318, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 21268; Mature: 21268

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLIDNYDSFTYNLYQYFCELGTEVMVKRNDELQLTDIEQLAPSHVVISPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCEEEECHHHCCCCEEEEECCCCCCCCCC
ISLAVIRHFADKLPILGVCLGHQALGQAFGARVVRARQVMHGKTSAICHSGQGVFRGLNQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCHHHHCCCC
PLTVTRYHSLVIATDSLPGRFELTAWTERGGEMDEIMGIRHRTLPLEGVQFHPESILSEQ
CEEEEEEEEEEEEECCCCCEEEEEEECCCCCCHHHHHCCHHCCCCCCCCEECHHHHHHHH
GHQLLDNFLKN
HHHHHHHHHCC
>Mature Secondary Structure
MLLLIDNYDSFTYNLYQYFCELGTEVMVKRNDELQLTDIEQLAPSHVVISPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCEEEECHHHCCCCEEEEECCCCCCCCCC
ISLAVIRHFADKLPILGVCLGHQALGQAFGARVVRARQVMHGKTSAICHSGQGVFRGLNQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCHHHHCCCC
PLTVTRYHSLVIATDSLPGRFELTAWTERGGEMDEIMGIRHRTLPLEGVQFHPESILSEQ
CEEEEEEEEEEEEECCCCCEEEEEEECCCCCCHHHHHCCHHCCCCCCCCEECHHHHHHHH
GHQLLDNFLKN
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3894673 [H]