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The map label for this gene is ureC

Identifier: 161751095

GI number: 161751095

Start: 1011144

End: 1012817

Strand: Reverse

Name: ureC

Synonym: ST1028

Alternate gene names: 161751095

Gene position: 1012817-1011144 (Counterclockwise)

Preceding gene: 15921276

Following gene: 15921274

Centisome position: 37.58

GC content: 36.38

Gene sequence:

>1674_bases
TTGAGAATAAGTAGGGAAAGATATTTTGAGTTGTATGGACCAACTGAAGGAGACAAAATTAGGCTAGGAGATACTAATCT
TTACATAACAATAGAAAAGGACTTAATTGCAAAAGGAGATGAGCTGGTTTTTGGAGCTGGCAAAACGGCTAGAGATGGTT
TGGGATTGTTACCAAACGTTAGGGAGGAAGAGGTGATGGATTTAATAATTACCAATGTAGTAATTCTCGACCCTTTATTA
GGAGTTATAAAAGCAGATATTGGGATAAAAGATGGTTTAATTGTTGGGATTGGTCATGGTGGCAATCCTTTTACAATGGA
TGGTGTAAATTTTGTTTTAGGCTCTTCAACTGAAATCATTTCCGGAGAAGGGTTAATTGCTACACCAGGTTTTATTGATA
CTCACATACATTGGGTTGCTCCACAGCAAGTTTTTGATGCTTTGTCAGCCGGATTTACAACACTAATTGGTGGTGGTACT
GGTCCAGCTGAAGGGACTAAGGCAACTACTGTAACTCCAGGGAGTTGGAATATTAAAATTATTGCTGAATCACTTGATTA
TTTCCCATTAAACTTTGCATTAACAGCTAAAGGTTCATCTAGTAGGATTACTATGGAAGAAGTATTAAGAAATGGTGCAT
CTGGTTTTAAGATTCATGAAGATTGGGGGGCTATGCCTAGAGTAATAGATGAAACTTTAACAGTTGCTGATGAATACGAT
GTTCAAGTAACAATACATACTGATACTTCAAATGAAAGTGGTTACTTAGAAGATACCCTTAATGCTATTAATGGTAGAAC
AATTCACGCTTACCACGTAGAAGGGGCTGGAGGAGGACATGCCCCAGATATTATTAAAATTTGTGCAGAACCAAATGTCT
TACCTTCATCGACAAATCCTACAAAACCTTATACAATACACACTTATGAGGAGCATTTGGAAATGTTAATGGCCGTGCAC
CATTTAAATCCAAAGGTTCCAGAAGATGTTGCTTATGCAGAATCAAGAATTAGGGAAGAGACAATGATGGCAGAGGATTA
TTTACATGATTTAGGAGCAATAAGTATGATGTCTTCAGATTCCCAAGCTATGGGAAGAGTTGGAGAAACTGGAATAAGAA
CTTTCCAACTTGCACACAAAATGAAAGATCTAGGGCTAATCCAAATAAATGATAATGAAAGGGTACTAAGATATTTAGCT
AAAATAACAATTAATCCAGCAATAACCCATGGAATTTCTGATTACGTAGGCACTTTAGCACCAGGACATATTGCTGATAT
TGTTCTGTGGGATCCAAGATTCTTTCCAGTAAAGCCTTACATGGTTATTAAAGGTGGTGCAATAACTTGGGCATTAATGG
GAGATACAAACGCTTCAATTGCTTATGCACAGCCAGTACTTTACAAACCAATGTTTGGATATTACTCTGCTAAAAGCGTC
TCATTCTTCTTCTCCGCGACTGATGGAGTAGAGAACTTATCGAAGATTGTAAGAAGAAGAGTCTTACCAGTCAAGAATAC
TAGGCATCTAACCAAAAAGGATATGAAATATAATGATATTTTACCAAAGATTGAGGTTAACCCAGATACTTATGAAGTTA
AAATTAATGGTATTGTACCAAAAGTTCCTCCTTCAAAATCATTACCGTTAACTCAATTATATTTCATATATTAG

Upstream 100 bases:

>100_bases
GAGGTGGAAGAAGAGTTACCGGGTTAAACGGTTTAACAGAAGGTTCTCTAGAACATAATAAGGAAGAATCTATTAAAAGA
GCAAAGGAGAGGGGGTTTGC

Downstream 100 bases:

>100_bases
GGTGATACCATGATTTTAGCTAAAAAGTTAGGAAAAGAAAGTGAAGCACATGAATTGATAGAGAAGGCTAAGGCATTAGG
GATTTTTAGAATAGTGGAGC

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MRISRERYFELYGPTEGDKIRLGDTNLYITIEKDLIAKGDELVFGAGKTARDGLGLLPNVREEEVMDLIITNVVILDPLL
GVIKADIGIKDGLIVGIGHGGNPFTMDGVNFVLGSSTEIISGEGLIATPGFIDTHIHWVAPQQVFDALSAGFTTLIGGGT
GPAEGTKATTVTPGSWNIKIIAESLDYFPLNFALTAKGSSSRITMEEVLRNGASGFKIHEDWGAMPRVIDETLTVADEYD
VQVTIHTDTSNESGYLEDTLNAINGRTIHAYHVEGAGGGHAPDIIKICAEPNVLPSSTNPTKPYTIHTYEEHLEMLMAVH
HLNPKVPEDVAYAESRIREETMMAEDYLHDLGAISMMSSDSQAMGRVGETGIRTFQLAHKMKDLGLIQINDNERVLRYLA
KITINPAITHGISDYVGTLAPGHIADIVLWDPRFFPVKPYMVIKGGAITWALMGDTNASIAYAQPVLYKPMFGYYSAKSV
SFFFSATDGVENLSKIVRRRVLPVKNTRHLTKKDMKYNDILPKIEVNPDTYEVKINGIVPKVPPSKSLPLTQLYFIY

Sequences:

>Translated_557_residues
MRISRERYFELYGPTEGDKIRLGDTNLYITIEKDLIAKGDELVFGAGKTARDGLGLLPNVREEEVMDLIITNVVILDPLL
GVIKADIGIKDGLIVGIGHGGNPFTMDGVNFVLGSSTEIISGEGLIATPGFIDTHIHWVAPQQVFDALSAGFTTLIGGGT
GPAEGTKATTVTPGSWNIKIIAESLDYFPLNFALTAKGSSSRITMEEVLRNGASGFKIHEDWGAMPRVIDETLTVADEYD
VQVTIHTDTSNESGYLEDTLNAINGRTIHAYHVEGAGGGHAPDIIKICAEPNVLPSSTNPTKPYTIHTYEEHLEMLMAVH
HLNPKVPEDVAYAESRIREETMMAEDYLHDLGAISMMSSDSQAMGRVGETGIRTFQLAHKMKDLGLIQINDNERVLRYLA
KITINPAITHGISDYVGTLAPGHIADIVLWDPRFFPVKPYMVIKGGAITWALMGDTNASIAYAQPVLYKPMFGYYSAKSV
SFFFSATDGVENLSKIVRRRVLPVKNTRHLTKKDMKYNDILPKIEVNPDTYEVKINGIVPKVPPSKSLPLTQLYFIY
>Mature_557_residues
MRISRERYFELYGPTEGDKIRLGDTNLYITIEKDLIAKGDELVFGAGKTARDGLGLLPNVREEEVMDLIITNVVILDPLL
GVIKADIGIKDGLIVGIGHGGNPFTMDGVNFVLGSSTEIISGEGLIATPGFIDTHIHWVAPQQVFDALSAGFTTLIGGGT
GPAEGTKATTVTPGSWNIKIIAESLDYFPLNFALTAKGSSSRITMEEVLRNGASGFKIHEDWGAMPRVIDETLTVADEYD
VQVTIHTDTSNESGYLEDTLNAINGRTIHAYHVEGAGGGHAPDIIKICAEPNVLPSSTNPTKPYTIHTYEEHLEMLMAVH
HLNPKVPEDVAYAESRIREETMMAEDYLHDLGAISMMSSDSQAMGRVGETGIRTFQLAHKMKDLGLIQINDNERVLRYLA
KITINPAITHGISDYVGTLAPGHIADIVLWDPRFFPVKPYMVIKGGAITWALMGDTNASIAYAQPVLYKPMFGYYSAKSV
SFFFSATDGVENLSKIVRRRVLPVKNTRHLTKKDMKYNDILPKIEVNPDTYEVKINGIVPKVPPSKSLPLTQLYFIY

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URE1_SULTO (Q972W0)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_376944.2
- ProteinModelPortal:   Q972W0
- SMR:   Q972W0
- GeneID:   1459007
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST1028
- NMPDR:   fig|273063.1.peg.1112
- HOGENOM:   HBG357507
- ProtClustDB:   PRK13207
- BioCyc:   STOK273063:ST1028-MONOMER
- BRENDA:   3.5.1.5
- GO:   GO:0005737
- HAMAP:   MF_01953
- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- PRINTS:   PR01752
- TIGRFAMs:   TIGR01792

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha; SSF51338 Metalo_hydrolase

EC number: =3.5.1.5

Molecular weight: Translated: 61124; Mature: 61124

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS01120 UREASE_1; PS00145 UREASE_2; PS51368 UREASE_3

Important sites: ACT_SITE 320-320 BINDING 219-219

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRISRERYFELYGPTEGDKIRLGDTNLYITIEKDLIAKGDELVFGAGKTARDGLGLLPNV
CCCCCCCEEEEECCCCCCEEEECCCEEEEEEEHHHHCCCCEEEEECCCCCCCCCCCCCCC
REEEVMDLIITNVVILDPLLGVIKADIGIKDGLIVGIGHGGNPFTMDGVNFVLGSSTEII
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEECCCEEEECCCCEEE
SGEGLIATPGFIDTHIHWVAPQQVFDALSAGFTTLIGGGTGPAEGTKATTVTPGSWNIKI
CCCCEEECCCCEECCEEEECHHHHHHHHHCCCEEEECCCCCCCCCCEEEEECCCCEEEEE
IAESLDYFPLNFALTAKGSSSRITMEEVLRNGASGFKIHEDWGAMPRVIDETLTVADEYD
EEECCCCEEEEEEEEECCCCCEEEHHHHHHCCCCCCEEECCCCCCHHHHHHHHEEECCCE
VQVTIHTDTSNESGYLEDTLNAINGRTIHAYHVEGAGGGHAPDIIKICAEPNVLPSSTNP
EEEEEEECCCCCCCCHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHEECCCCCCCCCCCC
TKPYTIHTYEEHLEMLMAVHHLNPKVPEDVAYAESRIREETMMAEDYLHDLGAISMMSSD
CCCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
SQAMGRVGETGIRTFQLAHKMKDLGLIQINDNERVLRYLAKITINPAITHGISDYVGTLA
HHHHHCCCHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHCCCHHHHHCHHHHHHCCC
PGHIADIVLWDPRFFPVKPYMVIKGGAITWALMGDTNASIAYAQPVLYKPMFGYYSAKSV
CCCEEEEEEECCCEECCCCEEEEECCEEEEEEECCCCCCEEEECCCCCCCCCCCCCCCEE
SFFFSATDGVENLSKIVRRRVLPVKNTRHLTKKDMKYNDILPKIEVNPDTYEVKINGIVP
EEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHCCCEEEECCCEEEEEECCCCC
KVPPSKSLPLTQLYFIY
CCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MRISRERYFELYGPTEGDKIRLGDTNLYITIEKDLIAKGDELVFGAGKTARDGLGLLPNV
CCCCCCCEEEEECCCCCCEEEECCCEEEEEEEHHHHCCCCEEEEECCCCCCCCCCCCCCC
REEEVMDLIITNVVILDPLLGVIKADIGIKDGLIVGIGHGGNPFTMDGVNFVLGSSTEII
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEECCCEEEECCCCEEE
SGEGLIATPGFIDTHIHWVAPQQVFDALSAGFTTLIGGGTGPAEGTKATTVTPGSWNIKI
CCCCEEECCCCEECCEEEECHHHHHHHHHCCCEEEECCCCCCCCCCEEEEECCCCEEEEE
IAESLDYFPLNFALTAKGSSSRITMEEVLRNGASGFKIHEDWGAMPRVIDETLTVADEYD
EEECCCCEEEEEEEEECCCCCEEEHHHHHHCCCCCCEEECCCCCCHHHHHHHHEEECCCE
VQVTIHTDTSNESGYLEDTLNAINGRTIHAYHVEGAGGGHAPDIIKICAEPNVLPSSTNP
EEEEEEECCCCCCCCHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHEECCCCCCCCCCCC
TKPYTIHTYEEHLEMLMAVHHLNPKVPEDVAYAESRIREETMMAEDYLHDLGAISMMSSD
CCCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
SQAMGRVGETGIRTFQLAHKMKDLGLIQINDNERVLRYLAKITINPAITHGISDYVGTLA
HHHHHCCCHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHCCCHHHHHCHHHHHHCCC
PGHIADIVLWDPRFFPVKPYMVIKGGAITWALMGDTNASIAYAQPVLYKPMFGYYSAKSV
CCCEEEEEEECCCEECCCCEEEEECCEEEEEEECCCCCCEEEECCCCCCCCCCCCCCCEE
SFFFSATDGVENLSKIVRRRVLPVKNTRHLTKKDMKYNDILPKIEVNPDTYEVKINGIVP
EEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHCCCEEEECCCEEEEEECCCCC
KVPPSKSLPLTQLYFIY
CCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479