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The map label for this gene is trpB2

Identifier: 161751092

GI number: 161751092

Start: 1562905

End: 1564200

Strand: Reverse

Name: trpB2

Synonym: ST1567

Alternate gene names: 161751092

Gene position: 1564200-1562905 (Counterclockwise)

Preceding gene: 15921871

Following gene: 15921863

Centisome position: 58.05

GC content: 36.96

Gene sequence:

>1296_bases
ATGCTCGAAAAAGTTAGATTCGACTTACCGCAAGATGAGATACCAACAGAGTGGTATAACATTTTACCAGATCTACCGGA
ACCATTACCAGAACCCCAGGATCCTACTGGAAAATCATTTGAAATATTAAAACAAGTATTACCAAGTAAAGTTCTTGAAC
TCGAATTCTCAAAAGAGAGATATATAAAGATACCGGAAGAGGTTCTTCAACGATATTTACAAGTTGGAAGACCAACACCA
ATAATAAGGGCTAGAAAACTGGAGGAATACCTAGGAGGATATATAAAGATATATATGAAAATGGAAAGTCACACTTATAC
TGGTTCACACAAGATAAATAGTGCATTAGCTCACGTATATTTTGCAAAACTTGATAATGCTAAATTCGTTTCAACTGAAA
CTGGTGCAGGGCAATGGGGATCTGCAGTAGCGTTAGCTTCTGCATTATTTAATATTCAAGCTCACATTTTCATGGTCAGA
ACTAGTTACTACGCAAAACCCTATAGAAGGTATCTAATGCAAATGTATAATGCACAAGTACATCCAAGTCCTTCAGAATT
CACCAGATACGGAAGAGAAGTTTTAGCTAAAGATCCCAACACACCGGGGTCATTAGGAATTGCTATATCAGAGGCTGTCT
ATTACGCCCTAGAAAATGGAGGAAAATACGTTGTAGGTAGTGTGGTAAACTCAGACATTCTCTTTAAAACAATTGCCGGA
ATGGAGGCAAAGAAGCAAATGGAAATGATTGGTGAAGACCCAGATTATATTATAGGAGTTGTTGGCGGAGGTTCAAATTA
CGCTGCTTTAGCTTATCCATTCTTAGGTGAAGAATTAAGAAAAGGTAAAGTAAGAAGAAAGTACATAGCATCTGGAGCAA
TAGAAGTACCAAAAATGACAAAAGGAGTTTATAAATACGATTATCCAGATACAGCAAAGATTTTGCCAATGCTAAAGATG
TATACTATTGGATCTGACTTCATACCAGCACCAGTTTATGCTGGAGGCTTAAGATATCATGCAGTAGCACCAACATTATC
GTTATTAATGTACAAAGGGATTGTACAAGCTAGGGATTATTCACAAGAAGAAGCATTTTCGTGGGCTAAATTGTTTAGTC
AAATTGAAGGATGGGTACCGGCACCAGAAACTAGTCATGCATTACCAATCTTAAAAGAAATAGTTGAGGAAGCTAAGAAG
AGTGGCGAAAAGAAAACAGTACTAATAAGCTTCTCAGGCCATGGATTATTGGATCTAGCTAACTACGCTGATGTGTTAGG
TTTTAATAAGGAATAA

Upstream 100 bases:

>100_bases
CTTACTCTATCAATTATGTCTTCCATCATTAAAATTACTACTAAAGGTGTATAAAAGAATTTCGAAAACGATAATAAAGG
GAAATAACATTAAATATCAC

Downstream 100 bases:

>100_bases
ATACGTGTTTGTTACACTAAATCTTATGATAGTTAACGAGGCTACAGAGTTTTCAAAATTGAGAAATGCCTTTTTATTGT
TAACAGTAACAGAAATTGTA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MLEKVRFDLPQDEIPTEWYNILPDLPEPLPEPQDPTGKSFEILKQVLPSKVLELEFSKERYIKIPEEVLQRYLQVGRPTP
IIRARKLEEYLGGYIKIYMKMESHTYTGSHKINSALAHVYFAKLDNAKFVSTETGAGQWGSAVALASALFNIQAHIFMVR
TSYYAKPYRRYLMQMYNAQVHPSPSEFTRYGREVLAKDPNTPGSLGIAISEAVYYALENGGKYVVGSVVNSDILFKTIAG
MEAKKQMEMIGEDPDYIIGVVGGGSNYAALAYPFLGEELRKGKVRRKYIASGAIEVPKMTKGVYKYDYPDTAKILPMLKM
YTIGSDFIPAPVYAGGLRYHAVAPTLSLLMYKGIVQARDYSQEEAFSWAKLFSQIEGWVPAPETSHALPILKEIVEEAKK
SGEKKTVLISFSGHGLLDLANYADVLGFNKE

Sequences:

>Translated_431_residues
MLEKVRFDLPQDEIPTEWYNILPDLPEPLPEPQDPTGKSFEILKQVLPSKVLELEFSKERYIKIPEEVLQRYLQVGRPTP
IIRARKLEEYLGGYIKIYMKMESHTYTGSHKINSALAHVYFAKLDNAKFVSTETGAGQWGSAVALASALFNIQAHIFMVR
TSYYAKPYRRYLMQMYNAQVHPSPSEFTRYGREVLAKDPNTPGSLGIAISEAVYYALENGGKYVVGSVVNSDILFKTIAG
MEAKKQMEMIGEDPDYIIGVVGGGSNYAALAYPFLGEELRKGKVRRKYIASGAIEVPKMTKGVYKYDYPDTAKILPMLKM
YTIGSDFIPAPVYAGGLRYHAVAPTLSLLMYKGIVQARDYSQEEAFSWAKLFSQIEGWVPAPETSHALPILKEIVEEAKK
SGEKKTVLISFSGHGLLDLANYADVLGFNKE
>Mature_431_residues
MLEKVRFDLPQDEIPTEWYNILPDLPEPLPEPQDPTGKSFEILKQVLPSKVLELEFSKERYIKIPEEVLQRYLQVGRPTP
IIRARKLEEYLGGYIKIYMKMESHTYTGSHKINSALAHVYFAKLDNAKFVSTETGAGQWGSAVALASALFNIQAHIFMVR
TSYYAKPYRRYLMQMYNAQVHPSPSEFTRYGREVLAKDPNTPGSLGIAISEAVYYALENGGKYVVGSVVNSDILFKTIAG
MEAKKQMEMIGEDPDYIIGVVGGGSNYAALAYPFLGEELRKGKVRRKYIASGAIEVPKMTKGVYKYDYPDTAKILPMLKM
YTIGSDFIPAPVYAGGLRYHAVAPTLSLLMYKGIVQARDYSQEEAFSWAKLFSQIEGWVPAPETSHALPILKEIVEEAKK
SGEKKTVLISFSGHGLLDLANYADVLGFNKE

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

COG id: COG1350

COG function: function code R; Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family

Homologues:

Organism=Escherichia coli, GI1787515, Length=405, Percent_Identity=27.1604938271605, Blast_Score=92, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6321412, Length=404, Percent_Identity=30.6930693069307, Blast_Score=129, Evalue=1e-30,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPB2_SULTO (Q970N1)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_377533.2
- ProteinModelPortal:   Q970N1
- SMR:   Q970N1
- GeneID:   1459606
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST1567
- NMPDR:   fig|273063.1.peg.1701
- HOGENOM:   HBG303148
- ProtClustDB:   PRK12391
- BioCyc:   STOK273063:ST1567-MONOMER
- BRENDA:   4.2.1.20
- HAMAP:   MF_00133
- InterPro:   IPR001926
- InterPro:   IPR006316
- InterPro:   IPR006653
- InterPro:   IPR023026
- TIGRFAMs:   TIGR01415

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.2.1.20

Molecular weight: Translated: 48335; Mature: 48335

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKVRFDLPQDEIPTEWYNILPDLPEPLPEPQDPTGKSFEILKQVLPSKVLELEFSKER
CCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCH
YIKIPEEVLQRYLQVGRPTPIIRARKLEEYLGGYIKIYMKMESHTYTGSHKINSALAHVY
HEECHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEEECCCEECCCHHHHHHHHHHH
FAKLDNAKFVSTETGAGQWGSAVALASALFNIQAHIFMVRTSYYAKPYRRYLMQMYNAQV
HHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHHHHHHHCCCC
HPSPSEFTRYGREVLAKDPNTPGSLGIAISEAVYYALENGGKYVVGSVVNSDILFKTIAG
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHCCHHHHHHHHC
MEAKKQMEMIGEDPDYIIGVVGGGSNYAALAYPFLGEELRKGKVRRKYIASGAIEVPKMT
CHHHHHHHHHCCCCCEEEEEEECCCCCEEEECHHHHHHHHHCHHHHHHHHCCCCCCCHHH
KGVYKYDYPDTAKILPMLKMYTIGSDFIPAPVYAGGLRYHAVAPTLSLLMYKGIVQARDY
CCCEECCCCCHHHHHHHHHHHHCCCCCCCCCHHCCCEEEEHHHHHHHHHHHHHHHHHCCC
SQEEAFSWAKLFSQIEGWVPAPETSHALPILKEIVEEAKKSGEKKTVLISFSGHGLLDLA
CHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHH
NYADVLGFNKE
HHHHHHCCCCC
>Mature Secondary Structure
MLEKVRFDLPQDEIPTEWYNILPDLPEPLPEPQDPTGKSFEILKQVLPSKVLELEFSKER
CCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCH
YIKIPEEVLQRYLQVGRPTPIIRARKLEEYLGGYIKIYMKMESHTYTGSHKINSALAHVY
HEECHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEEECCCEECCCHHHHHHHHHHH
FAKLDNAKFVSTETGAGQWGSAVALASALFNIQAHIFMVRTSYYAKPYRRYLMQMYNAQV
HHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHHHHHHHCCCC
HPSPSEFTRYGREVLAKDPNTPGSLGIAISEAVYYALENGGKYVVGSVVNSDILFKTIAG
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHCCHHHHHHHHC
MEAKKQMEMIGEDPDYIIGVVGGGSNYAALAYPFLGEELRKGKVRRKYIASGAIEVPKMT
CHHHHHHHHHCCCCCEEEEEEECCCCCEEEECHHHHHHHHHCHHHHHHHHCCCCCCCHHH
KGVYKYDYPDTAKILPMLKMYTIGSDFIPAPVYAGGLRYHAVAPTLSLLMYKGIVQARDY
CCCEECCCCCHHHHHHHHHHHHCCCCCCCCCHHCCCEEEEHHHHHHHHHHHHHHHHHCCC
SQEEAFSWAKLFSQIEGWVPAPETSHALPILKEIVEEAKKSGEKKTVLISFSGHGLLDLA
CHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHH
NYADVLGFNKE
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479