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The map label for this gene is uxaA [H]

Identifier: 15922893

GI number: 15922893

Start: 2570721

End: 2571884

Strand: Direct

Name: uxaA [H]

Synonym: ST2560

Alternate gene names: 15922893

Gene position: 2570721-2571884 (Clockwise)

Preceding gene: 15922892

Following gene: 15922894

Centisome position: 95.4

GC content: 36.51

Gene sequence:

>1164_bases
ATGGAAAAGGTTACTATTAAAGGTTATATAAGGGAAAACGGTAGTGTTGGAATAAGGAATCATGTTGCGATAATACCGGT
TGATGATTTATCAAATAGTGCAGCAGTAGCAGTTTCAAGAATTATTAGGGGCACAATTGCTTTACCTCATCCTTATGGTA
GGTTACAATTTGGGAAAGATTTAGATTTACTCTTCCACATATTGTCTGGGACCGGAGCAAACCCGAATGTTGCTGGAGCT
ATTGTTATTGGAATTGAGGATAACTGGGCTCATAAAGTTGCTGATAAAATCGCTGAAACCGGTAAACCAGTGGAAGTTTT
TCCAATTGAAGGAAATGGTGATTTAAGAGTAATTGAGAAAGCGTCTAGAAAGGCTAAAGAATTTGTTCAATACGCAAGTG
AGAAACAAAGGACAGAAGTTGACTTATCATCAATTGTTGTGAGTATAAAGTGTGGAGAGAGTGATACAACATCTGGTTTA
GCATCAAACCCAGCAACAGGCTATGCTGTAGATAAATTAATTGATTATGGTGCTACAGTTCTATTTGGTGAGACTTCAGA
GTTAACGGGAGCTGAGGACATAGTTGCTAATAGGATTCCAGATCTAACATTAAGAGAAAAATTCATGAAGATTTATAAAG
AGTACGTTAGTTTTATTGAATCACAAGGAGTTGATCTATTAGGCTCTCAGCCTACGGAAGGAAATATTAAAGGCGGTTTA
TCTACGATTGAAGAAAAGGCTTTAGGAAATATACAGAAACTTGGTACCAAACCAATCACATGTGTATTGGACTACTTAGA
TCCTCTTCCTTCCGGATCATCTCGCTTATGTTTCGTAAACACCTCTTCTGCTGCAGCTGAAGCAGTAACGTTATTTGCTG
CTAAAGGTTCTGTTCTACATTTATTCACAACTGGGCAGGGAAATGTTGTTGGTCATCCTATTATTCCAGTAATAAAAATA
TCGGCAAATCCTAAAACTGTAACAACAATGGCTGAACACATAGATGTTGATGTATCGGACTTACTTCAACTTAAGGTTTC
ATTAAAAGAGGCTGGAGAAAGAATATTTAATTATGCTTTAAGGGTAATGAATGGAAGATTAACATCAGCAGAAGTACTTC
AGCATGATGAATTCTCTCCTATAAAATTATACATAAGTGCATAA

Upstream 100 bases:

>100_bases
GACCTATAGGGATTGCTATATCCGATATCAAAGCTGGTGAGCACGTTCATATACATAATATAAAATCGATTAGGTGGGGA
AATTTAAAGAGGTGAGGTAA

Downstream 100 bases:

>100_bases
AAAATGAAGGTTTCTATTTTACCAGCGTCAATACCTTATGTAGATAATCCTATGCCAGAATGGGTTGATGAGTGGGGAGT
ACAATTATTTACAAAAGTTA

Product: hypothetical protein

Products: NA

Alternate protein names: Altronic acid hydratase [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MEKVTIKGYIRENGSVGIRNHVAIIPVDDLSNSAAVAVSRIIRGTIALPHPYGRLQFGKDLDLLFHILSGTGANPNVAGA
IVIGIEDNWAHKVADKIAETGKPVEVFPIEGNGDLRVIEKASRKAKEFVQYASEKQRTEVDLSSIVVSIKCGESDTTSGL
ASNPATGYAVDKLIDYGATVLFGETSELTGAEDIVANRIPDLTLREKFMKIYKEYVSFIESQGVDLLGSQPTEGNIKGGL
STIEEKALGNIQKLGTKPITCVLDYLDPLPSGSSRLCFVNTSSAAAEAVTLFAAKGSVLHLFTTGQGNVVGHPIIPVIKI
SANPKTVTTMAEHIDVDVSDLLQLKVSLKEAGERIFNYALRVMNGRLTSAEVLQHDEFSPIKLYISA

Sequences:

>Translated_387_residues
MEKVTIKGYIRENGSVGIRNHVAIIPVDDLSNSAAVAVSRIIRGTIALPHPYGRLQFGKDLDLLFHILSGTGANPNVAGA
IVIGIEDNWAHKVADKIAETGKPVEVFPIEGNGDLRVIEKASRKAKEFVQYASEKQRTEVDLSSIVVSIKCGESDTTSGL
ASNPATGYAVDKLIDYGATVLFGETSELTGAEDIVANRIPDLTLREKFMKIYKEYVSFIESQGVDLLGSQPTEGNIKGGL
STIEEKALGNIQKLGTKPITCVLDYLDPLPSGSSRLCFVNTSSAAAEAVTLFAAKGSVLHLFTTGQGNVVGHPIIPVIKI
SANPKTVTTMAEHIDVDVSDLLQLKVSLKEAGERIFNYALRVMNGRLTSAEVLQHDEFSPIKLYISA
>Mature_387_residues
MEKVTIKGYIRENGSVGIRNHVAIIPVDDLSNSAAVAVSRIIRGTIALPHPYGRLQFGKDLDLLFHILSGTGANPNVAGA
IVIGIEDNWAHKVADKIAETGKPVEVFPIEGNGDLRVIEKASRKAKEFVQYASEKQRTEVDLSSIVVSIKCGESDTTSGL
ASNPATGYAVDKLIDYGATVLFGETSELTGAEDIVANRIPDLTLREKFMKIYKEYVSFIESQGVDLLGSQPTEGNIKGGL
STIEEKALGNIQKLGTKPITCVLDYLDPLPSGSSRLCFVNTSSAAAEAVTLFAAKGSVLHLFTTGQGNVVGHPIIPVIKI
SANPKTVTTMAEHIDVDVSDLLQLKVSLKEAGERIFNYALRVMNGRLTSAEVLQHDEFSPIKLYISA

Specific function: D-galactarate metabolism; first step. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789516, Length=396, Percent_Identity=26.7676767676768, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1789475, Length=391, Percent_Identity=25.8312020460358, Blast_Score=121, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.7 [H]

Molecular weight: Translated: 41562; Mature: 41562

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKVTIKGYIRENGSVGIRNHVAIIPVDDLSNSAAVAVSRIIRGTIALPHPYGRLQFGKD
CCEEEEEEEEECCCCEEECCCEEEEEECCCCCHHHHHHHHHHHCCEECCCCCCCCCCCCC
LDLLFHILSGTGANPNVAGAIVIGIEDNWAHKVADKIAETGKPVEVFPIEGNGDLRVIEK
HHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEHHH
ASRKAKEFVQYASEKQRTEVDLSSIVVSIKCGESDTTSGLASNPATGYAVDKLIDYGATV
HHHHHHHHHHHHHHHHHHHEEHHHEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEE
LFGETSELTGAEDIVANRIPDLTLREKFMKIYKEYVSFIESQGVDLLGSQPTEGNIKGGL
EEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCH
STIEEKALGNIQKLGTKPITCVLDYLDPLPSGSSRLCFVNTSSAAAEAVTLFAAKGSVLH
HHHHHHHHCCHHHHCCCCHHHHHHHHCCCCCCCCCEEEEECCCHHHHEEEEEEECCCEEE
LFTTGQGNVVGHPIIPVIKISANPKTVTTMAEHIDVDVSDLLQLKVSLKEAGERIFNYAL
EEECCCCCEECCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
RVMNGRLTSAEVLQHDEFSPIKLYISA
HHHCCCCCHHHHHHCCCCCCEEEEEEC
>Mature Secondary Structure
MEKVTIKGYIRENGSVGIRNHVAIIPVDDLSNSAAVAVSRIIRGTIALPHPYGRLQFGKD
CCEEEEEEEEECCCCEEECCCEEEEEECCCCCHHHHHHHHHHHCCEECCCCCCCCCCCCC
LDLLFHILSGTGANPNVAGAIVIGIEDNWAHKVADKIAETGKPVEVFPIEGNGDLRVIEK
HHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEHHH
ASRKAKEFVQYASEKQRTEVDLSSIVVSIKCGESDTTSGLASNPATGYAVDKLIDYGATV
HHHHHHHHHHHHHHHHHHHEEHHHEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEE
LFGETSELTGAEDIVANRIPDLTLREKFMKIYKEYVSFIESQGVDLLGSQPTEGNIKGGL
EEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCH
STIEEKALGNIQKLGTKPITCVLDYLDPLPSGSSRLCFVNTSSAAAEAVTLFAAKGSVLH
HHHHHHHHCCHHHHCCCCHHHHHHHHCCCCCCCCCEEEEECCCHHHHEEEEEEECCCEEE
LFTTGQGNVVGHPIIPVIKISANPKTVTTMAEHIDVDVSDLLQLKVSLKEAGERIFNYAL
EEECCCCCEECCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
RVMNGRLTSAEVLQHDEFSPIKLYISA
HHHCCCCCHHHHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]