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The map label for this gene is nagA [H]

Identifier: 15922880

GI number: 15922880

Start: 2555627

End: 2556742

Strand: Direct

Name: nagA [H]

Synonym: ST2546

Alternate gene names: 15922880

Gene position: 2555627-2556742 (Clockwise)

Preceding gene: 15922878

Following gene: 15922881

Centisome position: 94.84

GC content: 34.68

Gene sequence:

>1116_bases
ATGGAGTTAAAATTAACAAACGCTAAGATCATAACACCTTATAAAGAAATTGAAAGGGGTAGTGTGATAATTAAAGATGG
TATAATTAGTGAAATATTAGAGGAAAGGACTGAGGGGGAAGACTTAGAGGGAATGCTCTTACTTCCAGCGTTTGTTGATA
TTCATACTCACGGAATTGGTGGATATGATTATACATCATGGGATAGTGAGGATGATTTCATAAAAAACGCTATAGGGATG
AAAAAGAAACTGATCCAACATGGTGTAACAACTTTCTTACCTACAACAGTTACAATGCCTAGAGAAAGTCTGTTGGAGGC
TTGTAAGGCTATATCACAGACAGATATTTTAGGACTCCACTTAGAAGGTCCTTATATAAGTGAAAAACATGCTGGTGCAC
AAGATGTAAGATATATAAGAAACCCAGACAAGAATGAAGTGTTGGAGTGTGTCAGAGAGAGTAATAATAAAGTAATAACA
ATAACTTATTCTCCCGAAAAAGATCTGGATTTTATTCCATTCATGTTAAGTCTGGGAATTTACCCTTCAATAGGACATAC
AGATGCAGATTATGAGACAGCAGTTAAAGCATTCCTCTTAGGTGCTAGTAGGGTTACACATTTATTTAATGCAATGAGGG
CATTTCATCATAGAGATCCAGGCGTAATTTTAGCTAGTATTAATTTTTCTCCATTTATTGAAATAATTCCAGACTTTATA
CACGTTGATAAAGAGGTGGTGAGGTTTTTAACTAAAATAGTTGATATAAAAAGAATTGTTGCAGTAACAGATTCTATAAT
AGCTACTGATCTTCAAGATGGTACTTATACTTTGGGTAAAATGAGGATAAGGGTTGAAAATGGTATTGCAAGGACTGAGG
ATGGAAAATTGGCCGGGAGTACTTTAACAATGGATAAGGCATTTAAAAATCTATCAAGTATTATAGGAATAAGGGAGGCT
TCACTCATATGTTCATATAATCCAGCAAGGGCAATAGGACTTAGTGACAGAGGGATTATTGAAAAGGGGAAGAGGGCTGA
CTTAATCGTAATGGATGAAAAGTTGAATGTTAAAAAAGTATTTATAAATGGAGAGGAGATTTTTTCTAGCAGTTAG

Upstream 100 bases:

>100_bases
TAAACCAATATTAATAATAGAAACATCCCTAGGATTTTTACATATAAACCCAAAAATCCCTCCCATACATTTTATACCTC
TCTAACTTTAATAAACCTTA

Downstream 100 bases:

>100_bases
ACAAAGAAGTGTTTCAACTGAGATTATAATCCTTAATATTTTCTAAAGTTAACTATTACCTTTCTTCATCGGAGTTGTAA
AAACTTGAAAAGGATATTAA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MELKLTNAKIITPYKEIERGSVIIKDGIISEILEERTEGEDLEGMLLLPAFVDIHTHGIGGYDYTSWDSEDDFIKNAIGM
KKKLIQHGVTTFLPTTVTMPRESLLEACKAISQTDILGLHLEGPYISEKHAGAQDVRYIRNPDKNEVLECVRESNNKVIT
ITYSPEKDLDFIPFMLSLGIYPSIGHTDADYETAVKAFLLGASRVTHLFNAMRAFHHRDPGVILASINFSPFIEIIPDFI
HVDKEVVRFLTKIVDIKRIVAVTDSIIATDLQDGTYTLGKMRIRVENGIARTEDGKLAGSTLTMDKAFKNLSSIIGIREA
SLICSYNPARAIGLSDRGIIEKGKRADLIVMDEKLNVKKVFINGEEIFSSS

Sequences:

>Translated_371_residues
MELKLTNAKIITPYKEIERGSVIIKDGIISEILEERTEGEDLEGMLLLPAFVDIHTHGIGGYDYTSWDSEDDFIKNAIGM
KKKLIQHGVTTFLPTTVTMPRESLLEACKAISQTDILGLHLEGPYISEKHAGAQDVRYIRNPDKNEVLECVRESNNKVIT
ITYSPEKDLDFIPFMLSLGIYPSIGHTDADYETAVKAFLLGASRVTHLFNAMRAFHHRDPGVILASINFSPFIEIIPDFI
HVDKEVVRFLTKIVDIKRIVAVTDSIIATDLQDGTYTLGKMRIRVENGIARTEDGKLAGSTLTMDKAFKNLSSIIGIREA
SLICSYNPARAIGLSDRGIIEKGKRADLIVMDEKLNVKKVFINGEEIFSSS
>Mature_371_residues
MELKLTNAKIITPYKEIERGSVIIKDGIISEILEERTEGEDLEGMLLLPAFVDIHTHGIGGYDYTSWDSEDDFIKNAIGM
KKKLIQHGVTTFLPTTVTMPRESLLEACKAISQTDILGLHLEGPYISEKHAGAQDVRYIRNPDKNEVLECVRESNNKVIT
ITYSPEKDLDFIPFMLSLGIYPSIGHTDADYETAVKAFLLGASRVTHLFNAMRAFHHRDPGVILASINFSPFIEIIPDFI
HVDKEVVRFLTKIVDIKRIVAVTDSIIATDLQDGTYTLGKMRIRVENGIARTEDGKLAGSTLTMDKAFKNLSSIIGIREA
SLICSYNPARAIGLSDRGIIEKGKRADLIVMDEKLNVKKVFINGEEIFSSS

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=426, Percent_Identity=28.8732394366197, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI224922791, Length=420, Percent_Identity=29.0476190476191, Blast_Score=149, Evalue=4e-36,
Organism=Escherichia coli, GI1786892, Length=382, Percent_Identity=28.2722513089005, Blast_Score=153, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17553768, Length=363, Percent_Identity=33.0578512396694, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI19920392, Length=394, Percent_Identity=29.9492385786802, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281361140, Length=408, Percent_Identity=29.1666666666667, Blast_Score=145, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41345; Mature: 41345

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKLTNAKIITPYKEIERGSVIIKDGIISEILEERTEGEDLEGMLLLPAFVDIHTHGIG
CCEEECCCEEECCHHHHCCCCEEEECHHHHHHHHHHCCCCCCCCEEEEEHEEEHEECCCC
GYDYTSWDSEDDFIKNAIGMKKKLIQHGVTTFLPTTVTMPRESLLEACKAISQTDILGLH
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCEECCCHHHHHHHHHHHCCCCEEEEE
LEGPYISEKHAGAQDVRYIRNPDKNEVLECVRESNNKVITITYSPEKDLDFIPFMLSLGI
ECCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHCCC
YPSIGHTDADYETAVKAFLLGASRVTHLFNAMRAFHHRDPGVILASINFSPFIEIIPDFI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
HVDKEVVRFLTKIVDIKRIVAVTDSIIATDLQDGTYTLGKMRIRVENGIARTEDGKLAGS
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCC
TLTMDKAFKNLSSIIGIREASLICSYNPARAIGLSDRGIIEKGKRADLIVMDEKLNVKKV
EEHHHHHHHHHHHHHHHHHHEEEEECCCCEEECCCCCCHHCCCCCCCEEEECCCCCEEEE
FINGEEIFSSS
EECHHHHHCCC
>Mature Secondary Structure
MELKLTNAKIITPYKEIERGSVIIKDGIISEILEERTEGEDLEGMLLLPAFVDIHTHGIG
CCEEECCCEEECCHHHHCCCCEEEECHHHHHHHHHHCCCCCCCCEEEEEHEEEHEECCCC
GYDYTSWDSEDDFIKNAIGMKKKLIQHGVTTFLPTTVTMPRESLLEACKAISQTDILGLH
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCEECCCHHHHHHHHHHHCCCCEEEEE
LEGPYISEKHAGAQDVRYIRNPDKNEVLECVRESNNKVITITYSPEKDLDFIPFMLSLGI
ECCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHCCC
YPSIGHTDADYETAVKAFLLGASRVTHLFNAMRAFHHRDPGVILASINFSPFIEIIPDFI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
HVDKEVVRFLTKIVDIKRIVAVTDSIIATDLQDGTYTLGKMRIRVENGIARTEDGKLAGS
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCC
TLTMDKAFKNLSSIIGIREASLICSYNPARAIGLSDRGIIEKGKRADLIVMDEKLNVKKV
EEHHHHHHHHHHHHHHHHHHEEEEECCCCEEECCCCCCHHCCCCCCCEEEECCCCCEEEE
FINGEEIFSSS
EECHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA