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The map label for this gene is coxL [H]

Identifier: 15922814

GI number: 15922814

Start: 2485140

End: 2487332

Strand: Direct

Name: coxL [H]

Synonym: ST2484

Alternate gene names: 15922814

Gene position: 2485140-2487332 (Clockwise)

Preceding gene: 15922812

Following gene: 15922815

Centisome position: 92.22

GC content: 36.3

Gene sequence:

>2193_bases
GTGTACGTGGGTCAACGCGTTAAAAGGAAGGAAGACCTTAAATTAATAACTGGATCTGGTAGATATATTGATGATATAGA
AATTCCTGGAAATCTTTATATAGCAATTTTAAGAAGTAGTGTTGCCCATGCAAAATTAAAGAAAATAGAGTATAGTGACG
TATTAAAATTGAACGGTGTTTATGGAGTAATAACCGGTTTAACAATTCCAGTTGAGAATAGACCAAGAAACTTTCCAATG
GCAAAAGACGAAATCTTGTATATGGGACAACCTATAGCTGCCGTTCTGGCTAAAGATAGGTACGTTGCGGTTGATGCTCT
CGATTATATTTCATATGATTATGAAGAATTGCCAGCCGTTATAGACCCAGAAGAAGCTATAAATAGTAAGGTAAAAGCTA
TAGAGGATTACGATAATATAATTTATAAGAAGACTTATTCTGGTGGAAATGCCGAAGAAGCTTATGAAAAATCTGACGTA
AAAATTGAGGAGAAATTAGTAATTTCAAGGGTTTACGCCGCACCGATGGAACCTAGAGGGTTAGTAGTAGATTATCAACA
AGATAGATTAACAGTATATGCCTCTACACAATCTCCACACTATATGAGATCTTTCTTGCTTTCAGCATTCGGAGATAAGG
TAAATGATATTAGAGTGATTCAAGCAGATGTTGGAGGTGCTTTTGGTTCAAAACTATTCCCATATCCAGAAGATTATATA
GCTGTATTCGCCGCGTTAACTTATAAAAGACCAGTTAAGCTAGTAAATACTAGAAGAGATGACTTATTTTCAACTTATCA
TTCGAGAGGTCAAATTCACAAGGTTAAGGTTGGTGCTTCTAAGGATGGTAAAATAAATTCCATATTAGATGATTTAATCA
TTGACCTTGGTGCTGCTTGGCATGGTACATACTTAGCTGATATTCCAGCAACTCTAATTACCGGTCCTTATGACATTAAG
AATGCTAAAGTTAATGTATTTGGTGTTTTAACAAACAAAACCCCTCTTGACCAATACAGAGGTGCTGGAAGACCTGAAGC
AGCATTTGTTTATGAGAGGATAATGGATATTGTTGCTGATGAACTAAAGATTGATCCAATTGAATTGAGGAGAAAGAATA
TAATTCAATCGACACCTTACAAGAACGTCATGGGTTTAACATACGATAGCGGCGATTATAATGCTTTACTTACTAAGGCT
GAAAGTTACTATAGGGAAATGGAGCAAAGAGCGGAAGAATTAAGAAGACAAGGAAAGAGAGTTGGTGTTGGTCTTTCATT
TTATATTGAGCAAAATAACTTCGGCCCTTGGGAAAGTGCATCAGTTAGACTTCTTTCCAATGGGAAAGTTGAGGTTGTGA
TAGGTGCTGCACCTCATGGTCAAGGCACAGCGACTGGAATAGCTCAAATAGTTGCTGATGAATTAGAAATTAGTATTGAC
GATGTTGAAGTCACATGGGGTGACACCGATAAGATATCCAATGCGTTTGGAACTTATGGTAGTAGAAGCCTAACATTAGC
TGGAAATGCTGCACTTCTTGCAAGTAGAAAATTAAAAGAAAATATAATGAAGTTAGCTGCACAATTCATGAAGAGTGATG
TTGAAGAACTGCAATATAAAGATGGTAAAGTATTTAATCCTAAGACTGGTAAATCAATGACACTGAAAGAAATAGCTATA
AAAGTTACAAGCAATCTAGGTGGAGTTTGGAGGTATAAAGCAGAACCTACATTAGAGGCTACGGCATCTTTTGGGTTTGA
TAATTATACCTTCCCCTATGGTTCACATATAGCTATGGTTGAAGTTACTGATGAAGGAGTAGTTAAAGTTCTAGATTATG
TTGCTATAGATGATATTGGTGTCGTTGTTAATCCAATGTTAGCTGAAGGTCAAGTACACGGTGGAGTAATTCAAGGATTT
GGAGAAACCTTGCTAGAGCAAATTGTTTATGATAATAACGGTAATTTATTAACATCGACGTTTGCAGATTATCTAATTCC
CTCAGCCGTTGAATCGTTTAACATGAAATGGTTCTACACAGAAATTGGTAAATCTAACGCGCCATTACCAGCAAAAGGAA
TAGGTGAAGGTGCTACAATTGGTGCACCACCAGCGTTAATTAGAGCTATAGAAAGGGCAATAGGTAAAAGATTAACTGCC
TTACCGGTAAAAATGGAAGAATTAAGTAAATAA

Upstream 100 bases:

>100_bases
ACTTATCTGTTTAAACGTGTTACGGAATCTTATCCTTTTTCATTTACTTGACTAAGTAAAAAGGCAAAATTTTTATGTAA
TGTATGATTTTTCATAAAAT

Downstream 100 bases:

>100_bases
TGTCTTTTTACTGGTTAAATAATCTTCTTTGAGAATAACTTAAAAAATTTTATTACATAAATTTAAAAGTAATGAAATCG
CACTATTATTTATGCCAAAA

Product: aldehyde oxidoreductase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 730; Mature: 730

Protein sequence:

>730_residues
MYVGQRVKRKEDLKLITGSGRYIDDIEIPGNLYIAILRSSVAHAKLKKIEYSDVLKLNGVYGVITGLTIPVENRPRNFPM
AKDEILYMGQPIAAVLAKDRYVAVDALDYISYDYEELPAVIDPEEAINSKVKAIEDYDNIIYKKTYSGGNAEEAYEKSDV
KIEEKLVISRVYAAPMEPRGLVVDYQQDRLTVYASTQSPHYMRSFLLSAFGDKVNDIRVIQADVGGAFGSKLFPYPEDYI
AVFAALTYKRPVKLVNTRRDDLFSTYHSRGQIHKVKVGASKDGKINSILDDLIIDLGAAWHGTYLADIPATLITGPYDIK
NAKVNVFGVLTNKTPLDQYRGAGRPEAAFVYERIMDIVADELKIDPIELRRKNIIQSTPYKNVMGLTYDSGDYNALLTKA
ESYYREMEQRAEELRRQGKRVGVGLSFYIEQNNFGPWESASVRLLSNGKVEVVIGAAPHGQGTATGIAQIVADELEISID
DVEVTWGDTDKISNAFGTYGSRSLTLAGNAALLASRKLKENIMKLAAQFMKSDVEELQYKDGKVFNPKTGKSMTLKEIAI
KVTSNLGGVWRYKAEPTLEATASFGFDNYTFPYGSHIAMVEVTDEGVVKVLDYVAIDDIGVVVNPMLAEGQVHGGVIQGF
GETLLEQIVYDNNGNLLTSTFADYLIPSAVESFNMKWFYTEIGKSNAPLPAKGIGEGATIGAPPALIRAIERAIGKRLTA
LPVKMEELSK

Sequences:

>Translated_730_residues
MYVGQRVKRKEDLKLITGSGRYIDDIEIPGNLYIAILRSSVAHAKLKKIEYSDVLKLNGVYGVITGLTIPVENRPRNFPM
AKDEILYMGQPIAAVLAKDRYVAVDALDYISYDYEELPAVIDPEEAINSKVKAIEDYDNIIYKKTYSGGNAEEAYEKSDV
KIEEKLVISRVYAAPMEPRGLVVDYQQDRLTVYASTQSPHYMRSFLLSAFGDKVNDIRVIQADVGGAFGSKLFPYPEDYI
AVFAALTYKRPVKLVNTRRDDLFSTYHSRGQIHKVKVGASKDGKINSILDDLIIDLGAAWHGTYLADIPATLITGPYDIK
NAKVNVFGVLTNKTPLDQYRGAGRPEAAFVYERIMDIVADELKIDPIELRRKNIIQSTPYKNVMGLTYDSGDYNALLTKA
ESYYREMEQRAEELRRQGKRVGVGLSFYIEQNNFGPWESASVRLLSNGKVEVVIGAAPHGQGTATGIAQIVADELEISID
DVEVTWGDTDKISNAFGTYGSRSLTLAGNAALLASRKLKENIMKLAAQFMKSDVEELQYKDGKVFNPKTGKSMTLKEIAI
KVTSNLGGVWRYKAEPTLEATASFGFDNYTFPYGSHIAMVEVTDEGVVKVLDYVAIDDIGVVVNPMLAEGQVHGGVIQGF
GETLLEQIVYDNNGNLLTSTFADYLIPSAVESFNMKWFYTEIGKSNAPLPAKGIGEGATIGAPPALIRAIERAIGKRLTA
LPVKMEELSK
>Mature_730_residues
MYVGQRVKRKEDLKLITGSGRYIDDIEIPGNLYIAILRSSVAHAKLKKIEYSDVLKLNGVYGVITGLTIPVENRPRNFPM
AKDEILYMGQPIAAVLAKDRYVAVDALDYISYDYEELPAVIDPEEAINSKVKAIEDYDNIIYKKTYSGGNAEEAYEKSDV
KIEEKLVISRVYAAPMEPRGLVVDYQQDRLTVYASTQSPHYMRSFLLSAFGDKVNDIRVIQADVGGAFGSKLFPYPEDYI
AVFAALTYKRPVKLVNTRRDDLFSTYHSRGQIHKVKVGASKDGKINSILDDLIIDLGAAWHGTYLADIPATLITGPYDIK
NAKVNVFGVLTNKTPLDQYRGAGRPEAAFVYERIMDIVADELKIDPIELRRKNIIQSTPYKNVMGLTYDSGDYNALLTKA
ESYYREMEQRAEELRRQGKRVGVGLSFYIEQNNFGPWESASVRLLSNGKVEVVIGAAPHGQGTATGIAQIVADELEISID
DVEVTWGDTDKISNAFGTYGSRSLTLAGNAALLASRKLKENIMKLAAQFMKSDVEELQYKDGKVFNPKTGKSMTLKEIAI
KVTSNLGGVWRYKAEPTLEATASFGFDNYTFPYGSHIAMVEVTDEGVVKVLDYVAIDDIGVVVNPMLAEGQVHGGVIQGF
GETLLEQIVYDNNGNLLTSTFADYLIPSAVESFNMKWFYTEIGKSNAPLPAKGIGEGATIGAPPALIRAIERAIGKRLTA
LPVKMEELSK

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=731, Percent_Identity=25.5813953488372, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI91823271, Length=707, Percent_Identity=25.1768033946252, Blast_Score=128, Evalue=2e-29,
Organism=Escherichia coli, GI1789246, Length=780, Percent_Identity=25.3846153846154, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1789230, Length=747, Percent_Identity=26.6398929049531, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1786478, Length=730, Percent_Identity=25.8904109589041, Blast_Score=145, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI17540638, Length=752, Percent_Identity=24.7340425531915, Blast_Score=151, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI32566215, Length=726, Percent_Identity=24.6556473829201, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17539860, Length=748, Percent_Identity=22.9946524064171, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI17737937, Length=745, Percent_Identity=24.8322147651007, Blast_Score=136, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24647199, Length=697, Percent_Identity=23.2424677187948, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24647193, Length=706, Percent_Identity=24.3626062322946, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24647201, Length=765, Percent_Identity=22.6143790849673, Blast_Score=97, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 80715; Mature: 80715

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVGQRVKRKEDLKLITGSGRYIDDIEIPGNLYIAILRSSVAHAKLKKIEYSDVLKLNGV
CCCCCCCCCCCCCEEEECCCCEEEEEECCCCEEEEEHHHHHHHHHHHHCCHHHEEEECCC
YGVITGLTIPVENRPRNFPMAKDEILYMGQPIAAVLAKDRYVAVDALDYISYDYEELPAV
EEEEECCEEEECCCCCCCCCCCCCEEECCCCHHHHHHCCCEEEEEHHHHHCCCHHHCCCC
IDPEEAINSKVKAIEDYDNIIYKKTYSGGNAEEAYEKSDVKIEEKLVISRVYAAPMEPRG
CCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
LVVDYQQDRLTVYASTQSPHYMRSFLLSAFGDKVNDIRVIQADVGGAFGSKLFPYPEDYI
EEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCHHHH
AVFAALTYKRPVKLVNTRRDDLFSTYHSRGQIHKVKVGASKDGKINSILDDLIIDLGAAW
HHHHHHHHCCCHHHHCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCC
HGTYLADIPATLITGPYDIKNAKVNVFGVLTNKTPLDQYRGAGRPEAAFVYERIMDIVAD
CCCCHHCCCHHHCCCCCCCCCCEEEEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHH
ELKIDPIELRRKNIIQSTPYKNVMGLTYDSGDYNALLTKAESYYREMEQRAEELRRQGKR
HHCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCE
VGVGLSFYIEQNNFGPWESASVRLLSNGKVEVVIGAAPHGQGTATGIAQIVADELEISID
ECCEEEEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHEEEEE
DVEVTWGDTDKISNAFGTYGSRSLTLAGNAALLASRKLKENIMKLAAQFMKSDVEELQYK
EEEEEECCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DGKVFNPKTGKSMTLKEIAIKVTSNLGGVWRYKAEPTLEATASFGFDNYTFPYGSHIAMV
CCCEECCCCCCCEEHHHHHEEEECCCCCEEEEECCCCHHHHHHCCCCCCCCCCCCEEEEE
EVTDEGVVKVLDYVAIDDIGVVVNPMLAEGQVHGGVIQGFGETLLEQIVYDNNGNLLTST
EECCCCHHHHHHHHHHCCCCCEECCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEHHH
FADYLIPSAVESFNMKWFYTEIGKSNAPLPAKGIGEGATIGAPPALIRAIERAIGKRLTA
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEE
LPVKMEELSK
CCCCHHHHCC
>Mature Secondary Structure
MYVGQRVKRKEDLKLITGSGRYIDDIEIPGNLYIAILRSSVAHAKLKKIEYSDVLKLNGV
CCCCCCCCCCCCCEEEECCCCEEEEEECCCCEEEEEHHHHHHHHHHHHCCHHHEEEECCC
YGVITGLTIPVENRPRNFPMAKDEILYMGQPIAAVLAKDRYVAVDALDYISYDYEELPAV
EEEEECCEEEECCCCCCCCCCCCCEEECCCCHHHHHHCCCEEEEEHHHHHCCCHHHCCCC
IDPEEAINSKVKAIEDYDNIIYKKTYSGGNAEEAYEKSDVKIEEKLVISRVYAAPMEPRG
CCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
LVVDYQQDRLTVYASTQSPHYMRSFLLSAFGDKVNDIRVIQADVGGAFGSKLFPYPEDYI
EEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCHHHH
AVFAALTYKRPVKLVNTRRDDLFSTYHSRGQIHKVKVGASKDGKINSILDDLIIDLGAAW
HHHHHHHHCCCHHHHCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCC
HGTYLADIPATLITGPYDIKNAKVNVFGVLTNKTPLDQYRGAGRPEAAFVYERIMDIVAD
CCCCHHCCCHHHCCCCCCCCCCEEEEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHH
ELKIDPIELRRKNIIQSTPYKNVMGLTYDSGDYNALLTKAESYYREMEQRAEELRRQGKR
HHCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCE
VGVGLSFYIEQNNFGPWESASVRLLSNGKVEVVIGAAPHGQGTATGIAQIVADELEISID
ECCEEEEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHEEEEE
DVEVTWGDTDKISNAFGTYGSRSLTLAGNAALLASRKLKENIMKLAAQFMKSDVEELQYK
EEEEEECCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DGKVFNPKTGKSMTLKEIAIKVTSNLGGVWRYKAEPTLEATASFGFDNYTFPYGSHIAMV
CCCEECCCCCCCEEHHHHHEEEECCCCCEEEEECCCCHHHHHHCCCCCCCCCCCCEEEEE
EVTDEGVVKVLDYVAIDDIGVVVNPMLAEGQVHGGVIQGFGETLLEQIVYDNNGNLLTST
EECCCCHHHHHHHHHHCCCCCEECCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEHHH
FADYLIPSAVESFNMKWFYTEIGKSNAPLPAKGIGEGATIGAPPALIRAIERAIGKRLTA
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEE
LPVKMEELSK
CCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 12515558; 10430865; 12475995 [H]